Perilla ketone (BioDeep_00000619682)

Main id: BioDeep_00000017667

 

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


1-(furan-3-yl)-4-methylpentan-1-one

化学式: C10H14O2 (166.09937440000002)
中文名称: 紫苏酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)CCC(=O)C1=COC=C1
InChI: InChI=1S/C10H14O2/c1-8(2)3-4-10(11)9-5-6-12-7-9/h5-8H,3-4H2,1-2H3

描述信息

Perilla ketone is a naturally occurring xenobiotic compound. Perilla ketone is activated by pulmonary P450 cytochrome enzymes in the lung, resulting in severe pulmonary damage and development of diffuse pulmonary edema[1].
Perilla ketone is a naturally occurring xenobiotic compound. Perilla ketone is activated by pulmonary P450 cytochrome enzymes in the lung, resulting in severe pulmonary damage and development of diffuse pulmonary edema[1].

同义名列表

10 个代谢物同义名

1-(furan-3-yl)-4-methylpentan-1-one; 1-Pentanone,1-(3-furanyl)-4-methyl-; 1-(3-Furanyl)-4-methyl-1-pentanone; 1-furan-3-yl-4-methylpentan-1-one; 1-(3-Furyl)-4-methyl-1-pentanone; Purple Mint Plant Isolate; beta-Furyl isoamyl ketone; Purple mint plant extract; Perilla ketone; Perilla ketone



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

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23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Peina Zhou, Yongfang Shao, Zheng Jiang, Jingjie Dang, Cheng Qu, Qinan Wu. The revealing of a novel double bond reductase related to perilla ketone biosynthesis in Perilla frutescens. BMC plant biology. 2023 Jun; 23(1):345. doi: 10.1186/s12870-023-04345-1. [PMID: 37391700]
  • A Bassoli, G Borgonovo, G Morini, L De Petrocellis, A Schiano Moriello, V Di Marzo. Analogues of perillaketone as highly potent agonists of TRPA1 channel. Food chemistry. 2013 Dec; 141(3):2044-51. doi: 10.1016/j.foodchem.2013.05.063. [PMID: 23870926]
  • Won Ho Seo, Hyung Hee Baek. Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf. Journal of agricultural and food chemistry. 2009 Dec; 57(24):11537-42. doi: 10.1021/jf902669d. [PMID: 20000853]
  • Angela Bassoli, Gigliola Borgonovo, Sara Caimi, Leonardo Scaglioni, Gabriella Morini, Aniello Schiano Moriello, Vincenzo Di Marzo, Luciano De Petrocellis. Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens. Bioorganic & medicinal chemistry. 2009 Feb; 17(4):1636-9. doi: 10.1016/j.bmc.2008.12.057. [PMID: 19162486]
  • Michiho Ito, Gisho Honda, Kongmany Sydara. Perilla frutescens var. frutescens in northern Laos. Journal of natural medicines. 2008 Apr; 62(2):251-8. doi: 10.1007/s11418-007-0213-0. [PMID: 18404336]
  • Jonathan R Sanders, N Adrienne Pou, Robert J Roselli. Neutral and DEAE dextrans as tracers for assessing lung microvascular barrier permeability and integrity. Journal of applied physiology (Bethesda, Md. : 1985). 2002 Jul; 93(1):251-62. doi: 10.1152/japplphysiol.00635.2000. [PMID: 12070212]
  • V J Abernathy, N A Pou, R E Parker, R J Roselli. Evaluation of perilla ketone-induced unilateral lung injury using external gamma scanning. Journal of applied physiology (Bethesda, Md. : 1985). 1994 Jan; 76(1):138-45. doi: 10.1152/jappl.1994.76.1.138. [PMID: 8175497]
  • V J Abernathy, R J Roselli, R E Parker, N A Pou. Effects of Perilla ketone on the in situ sheep lung. Journal of applied physiology (Bethesda, Md. : 1985). 1992 Feb; 72(2):505-14. doi: 10.1152/jappl.1992.72.2.505. [PMID: 1559925]
  • J W Coggeshall, P L Lefferts, M J Butterfield, G R Bernard, F E Carroll, N A Pou, J R Snapper. Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep. The American review of respiratory disease. 1987 Dec; 136(6):1453-8. doi: 10.1164/ajrccm/136.6.1453. [PMID: 3688648]
  • Y Koezuka, G Honda, M Tabata. An intestinal propulsion promoting substance from Perilla frutescens and its mechanism of action. Planta medica. 1985 Dec; ?(6):480-2. doi: ". [PMID: 4095195]
  • R Breeze. Respiratory disease in adult cattle. The Veterinary clinics of North America. Food animal practice. 1985 Jul; 1(2):311-46. doi: 10.1016/s0749-0720(15)31329-3. [PMID: 3907777]
  • J E Garst, W C Wilson, N C Kristensen, P C Harrison, J E Corbin, J Simon, R M Philpot, R R Szabo. Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system. Journal of animal science. 1985 Jan; 60(1):248-57. doi: 10.2527/jas1985.601248x. [PMID: 3972746]
  • R G Breeze, J R Carlson. Chemical-induced lung injury in domestic animals. Advances in veterinary science and comparative medicine. 1982; 26(?):201-31. doi: ". [PMID: 6758539]
  • B J Wilson, J E Garst, R D Linnabary, R B Channell. Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton. Science (New York, N.Y.). 1977 Aug; 197(4303):573-4. doi: 10.1126/science.877573. [PMID: 877573]