Myricanone (BioDeep_00000616512)

PANOMIX_OTCML-2023 natural product

代谢物信息卡片

3,15-dihydroxy-16,17-dimethoxytricyclo[12.3.1.1^{2,6}]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one

化学式: C21H24O5 (356.1624)
中文名称: 杨梅酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C2C=C(CCCCC(=O)CCC3=CC2=C(C=C3)O)C(=C1OC)O
InChI: InChI=1S/C21H24O5/c1-25-20-17-12-14(19(24)21(20)26-2)5-3-4-6-15(22)9-7-13-8-10-18(23)16(17)11-13/h8,10-12,23-24H,3-7,9H2,1-2H3

描述信息

同义名列表

2 个代谢物同义名

3,15-dihydroxy-16,17-dimethoxytricyclo[12.3.1.1^{2,6}]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one; Myricanone

数据库引用编号

6 个数据库交叉引用编号

ChEBI: CHEBI:141540
PubChem: 161748
Metlin: METLIN87203
ChEMBL: CHEMBL2152655
CAS: 32492-74-3
LOTUS: LTS0086808

分类词条

Biaryl type diarylheptanoids

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

62 个相关的物种来源信息

2759 - Eukaryota: LTS0086808
3398 - Magnoliopsida: LTS0086808
190583 - Morella: LTS0086808
384999 - Morella adenophora: 10.1016/J.PHYTOCHEM.2014.04.003
3510 - Morella cerifera:
3510 - Morella cerifera: 10.1021/NP960230K
3510 - Morella cerifera: 10.1248/CPB.48.1427
3510 - Morella cerifera: LTS0086808
385002 - Morella esculenta: 10.1016/0031-9422(88)83145-5
385002 - Morella esculenta: LTS0086808
385008 - Morella nana: 10.1002/HLCA.200790175
385008 - Morella nana: LTS0086808
262757 - Morella rubra:
262757 - Morella rubra: 10.1002/CBDV.201600247
262757 - Morella rubra: 10.1016/J.JAMS.2013.05.003
262757 - Morella rubra: 10.1016/J.PHYTOCHEM.2014.04.003
262757 - Morella rubra: 10.1016/S0968-0896(02)00314-0
262757 - Morella rubra: 10.1021/NP300212C
262757 - Morella rubra: 10.1080/14786419.2010.516749
262757 - Morella rubra: 10.1159/000371738
262757 - Morella rubra: 10.1248/BPB.24.259
262757 - Morella rubra: 10.1248/CPB.35.2569
262757 - Morella rubra: 10.1248/CPB.50.208
262757 - Morella rubra: 10.1248/YAKUSHI1947.104.1_37
262757 - Morella rubra: 10.3390/MOLECULES22122266
262757 - Morella rubra: 10.3736/JINTEGRMED2013057
262757 - Morella rubra: LTS0086808
385014 - Morella salicifolia: 10.3390/MOLECULES22122266
3509 - Myrica: LTS0086808
29739 - Myrica gale: 10.1248/CPB.43.1674
29739 - Myrica gale: LTS0086808
385016 - Myrica gale var. tomentosa: 10.1248/CPB.43.1674
262756 - Myrica nagi:
262756 - Myrica nagi: 10.1002/CBDV.201600247
262756 - Myrica nagi: 10.1016/0031-9422(80)87049-X
262756 - Myrica nagi: 10.1016/J.JAMS.2013.05.003
262756 - Myrica nagi: 10.1016/J.PHYTOCHEM.2014.04.003
262756 - Myrica nagi: 10.1016/S0968-0896(02)00314-0
262756 - Myrica nagi: 10.1021/NP300212C
262756 - Myrica nagi: 10.1039/C29700001206
262756 - Myrica nagi: 10.1159/000371738
262756 - Myrica nagi: 10.1248/CPB.50.208
262756 - Myrica nagi: 10.3736/JINTEGRMED2013057
26766 - Myricaceae: LTS0086808
36011 - Nageia: LTS0086808
36012 - Nageia nagi:
36012 - Nageia nagi: 10.1002/CBDV.201600247
36012 - Nageia nagi: 10.1016/0031-9422(80)87049-X
36012 - Nageia nagi: 10.1016/J.JAMS.2013.05.003
36012 - Nageia nagi: 10.1016/J.PHYTOCHEM.2014.04.003
36012 - Nageia nagi: 10.1016/S0968-0896(02)00314-0
36012 - Nageia nagi: 10.1021/NP300212C
36012 - Nageia nagi: 10.1039/C29700001206
36012 - Nageia nagi: 10.1159/000371738
36012 - Nageia nagi: 10.1248/CPB.50.208
36012 - Nageia nagi: 10.3736/JINTEGRMED2013057
36012 - Nageia nagi: LTS0086808
58019 - Pinopsida: LTS0086808
3362 - Podocarpaceae: LTS0086808
35493 - Streptophyta: LTS0086808
58023 - Tracheophyta: LTS0086808
33090 - Viridiplantae: LTS0086808

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Corinne Vanucci-Bacqué, Florence Bedos-Belval. Anti-inflammatory activity of naturally occuring diarylheptanoids - A review. Bioorganic & medicinal chemistry. 2021 02; 31(?):115971. doi: 10.1016/j.bmc.2020.115971. [PMID: 33422907]
Edna Makule, Thomas J Schmidt, Jörg Heilmann, Birgit Kraus. Diarylheptanoid Glycosides of Morella salicifolia Bark. Molecules (Basel, Switzerland). 2017 Dec; 22(12):. doi: 10.3390/molecules22122266. [PMID: 29257058]
Ya-Chih Ting, Horng-Huey Ko, Hui-Chun Wang, Chien-Fang Peng, Hsun-Shuo Chang, Pei-Chen Hsieh, Ih-Sheng Chen. Biological evaluation of secondary metabolites from the roots of Myrica adenophora. Phytochemistry. 2014 Jul; 103(?):89-98. doi: 10.1016/j.phytochem.2014.04.003. [PMID: 24810013]
Avijit Paul, Sreemanti Das, Jayeeta Das, Asmita Samadder, Kausik Bishayee, Ratan Sadhukhan, Anisur Rahman Khuda-Bukhsh. Diarylheptanoid-myricanone isolated from ethanolic extract of Myrica cerifera shows anticancer effects on HeLa and PC3 cell lines: signalling pathway and drug-DNA interaction. Journal of integrative medicine. 2013 Nov; 11(6):405-15. doi: 10.3736/jintegrmed2013057. [PMID: 24299604]
Avijit Paul, Jayeeta Das, Sreemanti Das, Asmita Samadder, Anisur Rahman Khuda-Bukhsh. Anticancer potential of myricanone, a major bioactive component of Myrica cerifera: novel signaling cascade for accomplishing apoptosis. Journal of acupuncture and meridian studies. 2013 Aug; 6(4):188-98. doi: 10.1016/j.jams.2013.05.003. [PMID: 23972241]
Morio Yoshimura, Saori Yamakami, Yoshiaki Amakura, Takashi Yoshida. Diarylheptanoid sulfates and related compounds from Myrica rubra bark. Journal of natural products. 2012 Oct; 75(10):1798-802. doi: 10.1021/np300212c. [PMID: 23066712]
Jing Tao, Toshio Morikawa, Iwao Toguchida, Shin Ando, Hisashi Matsuda, Masayuki Yoshikawa. Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene. Bioorganic & medicinal chemistry. 2002 Dec; 10(12):4005-12. doi: 10.1016/s0968-0896(02)00314-0. [PMID: 12413852]