LPlasCho (BioDeep_00000597761)

 

Secondary id: BioDeep_00000031497


代谢物信息卡片


3,5,9-Trioxa-4-phosphapentacos-10-en-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, [R-(Z)]-

化学式: C24H50NO6P (479.33755700000006)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 66.67%

分子结构信息

SMILES: CCCCCCCCCCCCCC/C=C\OC[C@@H](O)COP(=O)([O-])OCC[N+](C)(C)C
InChI: InChI=1S/C24H50NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h18,20,24,26H,5-17,19,21-23H2,1-4H3/b20-18-/t24-/m1/s1

描述信息

同义名列表

8 个代谢物同义名

1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine; Lysoplasmenylcholine; PC(P-16:0/0:0); LPC(P-16:0); LPC O-16:1; LPlasCho; 3,5,9-Trioxa-4-phosphapentacos-10-en-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, [R-(Z)]-; GPCho(O-16:1(1Z)/0:0)



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Haruka Hakoi, Yoshimi Miki, Saki Nomura, Kimiko Nakajima, Chiaki Terashima-Murase, Takuya Takeichi, Shigetoshi Sano, Masashi Akiyama, Shin-Ichi Sakasegawa, Makoto Murakami, Kei Yamamoto. Lysophospholipase D from Thermocrispum limits psoriatic inflammation by hydrolyzing epidermal lysoplasmalogen produced by group IIF secreted phospholipase A2. Biochimie. 2023 Oct; ?(?):. doi: 10.1016/j.biochi.2023.09.027. [PMID: 37802209]
  • Suzanne A E van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J A Hendriks, Jeroen F J Bogie, Jan B van Klinken, Frederic M Vaz, Aldo Jongejan, Menno P J de Winther, Noam Zelcer. Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages. Journal of lipid research. 2023 Feb; 64(2):100325. doi: 10.1016/j.jlr.2022.100325. [PMID: 36592658]
  • Iffat Ara Sonia Rahman, Kazuhito Tsuboi, Zahir Hussain, Ryouhei Yamashita, Yoko Okamoto, Toru Uyama, Naoshi Yamazaki, Tamotsu Tanaka, Akira Tokumura, Natsuo Ueda. Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE7. Biochimica et biophysica acta. 2016 12; 1861(12 Pt A):1881-1892. doi: 10.1016/j.bbalip.2016.09.008. [PMID: 27637550]
  • Max T Bourdillon, Benjamin A Ford, Ashley T Knulty, Colleen N Gray, Miao Zhang, David Ford, Ryan D McCulla. Oxidation of Plasmalogen, Low-Density Lipoprotein and RAW 264.7 Cells by Photoactivatable Atomic Oxygen Precursors. Photochemistry and photobiology. 2014 Mar; 90(2):386-93. doi: 10.1111/php.12201. [PMID: 27096146]
  • Bradley D Martinson, Carolyn J Albert, John A Corbett, Robert B Wysolmerski, David A Ford. Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells. Journal of lipid research. 2003 Sep; 44(9):1686-91. doi: 10.1194/jlr.m300018-jlr200. [PMID: 12810819]
  • Carolyn J Albert, Jan R Crowley, Fong-Fu Hsu, Arun K Thukkani, David A Ford. Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes. The Journal of biological chemistry. 2002 Feb; 277(7):4694-703. doi: 10.1074/jbc.m110875200. [PMID: 11836259]
  • C J Albert, J R Crowley, F F Hsu, A K Thukkani, D A Ford. Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal. The Journal of biological chemistry. 2001 Jun; 276(26):23733-41. doi: 10.1074/jbc.m101447200. [PMID: 11301330]
  • D Reiss, K Beyer, B Engelmann. Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro. The Biochemical journal. 1997 May; 323 ( Pt 3)(?):807-14. doi: 10.1042/bj3230807. [PMID: 9169616]
  • M Schonefeld, S Noble, A M Bertorello, L J Mandel, M H Creer, D Portilla. Hypoxia-induced amphiphiles inhibit renal Na+, K(+)-ATPase. Kidney international. 1996 May; 49(5):1289-96. doi: 10.1038/ki.1996.184. [PMID: 8731093]
  • D J Hanahan, T Nouchi, S T Weintraub, M S Olson. Novel route to preparation of high purity lysoplasmenylethanolamine. Journal of lipid research. 1990 Nov; 31(11):2113-7. doi: 10.1016/s0022-2275(20)42276-x. [PMID: 2086708]
  • R A Wolf, R W Gross. Semi-synthetic approach for the preparation of homogeneous plasmenylethanolamine utilizing phospholipase D from Streptomyces chromofuscus. Journal of lipid research. 1985 May; 26(5):629-33. doi: 10.1016/s0022-2275(20)34351-0. [PMID: 4020302]
  • . . . . doi: . [PMID: 21515882]