CARTEOLOL (BioDeep_00000408906)
Main id: BioDeep_00000001928
代谢物信息卡片
CARTEOLOL
化学式: C16H24N2O3 (292.17868339999995)
中文名称: 卡替洛尔
谱图信息:
最多检出来源 Homo sapiens(urine) 95.83%
分子结构信息
SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O
InChI: InChI=1S/C16H24N2O3/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20)
描述信息
C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AA - Beta blocking agents, non-selective
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01ED - Beta blocking agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013565 - Sympatholytics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Riku Arai, Daisuke Fukamachi, Masaki Monden, Naotaka Akutsu, Nobuhiro Murata, Yasuo Okumura. Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease.
Internal medicine (Tokyo, Japan).
2021 Jan; 60(1):79-83. doi:
10.2169/internalmedicine.5598-20. [PMID: 32830185] - Dzmitry Shcharbin, Maria Bryszewska, Serge Mignani, Xiangyang Shi, Jean-Pierre Majoral. Phosphorus dendrimers as powerful nanoplatforms for drug delivery, as fluorescent probes and for liposome interaction studies: A concise overview.
European journal of medicinal chemistry.
2020 Dec; 208(?):112788. doi:
10.1016/j.ejmech.2020.112788. [PMID: 32883637] - Jia Wu, Xue Xiao, Zhenqun Li, Li Jia. Enantioseparation of chiral β-blockers using polynorepinephrine-coated nanoparticles and chiral capillary electrophoresis.
Analytical and bioanalytical chemistry.
2019 Apr; 411(10):2121-2129. doi:
10.1007/s00216-019-01641-4. [PMID: 30734853] - Dongsheng Xu, Huikai Shao, Rongying Luo, Qiqin Wang, Elena Sánchez-López, Salvatore Fanali, Maria Luisa Marina, Zhengjin Jiang. A facile and efficient single-step approach for the fabrication of vancomycin functionalized polymer-based monolith as chiral stationary phase for nano-liquid chromatography.
Journal of chromatography. A.
2018 Jul; 1557(?):43-50. doi:
10.1016/j.chroma.2018.05.004. [PMID: 29739612] - Ming Shan, Ting-Jun Fan. Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway.
Toxicology in vitro : an international journal published in association with BIBRA.
2016 Sep; 35(?):36-42. doi:
10.1016/j.tiv.2016.05.008. [PMID: 27216471] - Qing Yao, Xianyong Yu, Tongyin Zheng, Heting Liu, Ying Yang, Pinggui Yi. Spectroscopic studies on the interaction of carteolol hydrochloride and urea-induced bovine serum albumin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2013 Sep; 113(?):447-51. doi:
10.1016/j.saa.2013.04.129. [PMID: 23747387] - Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
10.1124/dmd.112.047068. [PMID: 22961681] - Imju Jeong, Bok Hee Choi, Shin Hee Yoon, Sang June Hahn. Carvedilol blocks the cloned cardiac Kv1.5 channels in a β-adrenergic receptor-independent manner.
Biochemical pharmacology.
2012 Feb; 83(4):497-505. doi:
10.1016/j.bcp.2011.11.019. [PMID: 22146582] - V A Badar, Sachin K Hiware, Meena P Shrivastava, V R Thawani, M M Hardas. Comparison of nebivolol and atenolol on blood pressure, blood sugar, and lipid profile in patients of essential hypertension.
Indian journal of pharmacology.
2011 Jul; 43(4):437-40. doi:
10.4103/0253-7613.83117. [PMID: 21845001] - Ling Zou, Ashwin Nair, Hong Weng, Yi-Ting Tsai, Zhibing Hu, Liping Tang. Intraocular pressure changes: an important determinant of the biocompatibility of intravitreous implants.
PloS one.
2011; 6(12):e28720. doi:
10.1371/journal.pone.0028720. [PMID: 22194895] - Kazuhide Kawase, Tetsuya Yamamoto, Tomoyuki Muramatsu, Junji Ono, Toru Nakajima, Atsuko Matsuhisa, Torao Sugiura, Masayoshi Migita, Yuji Ishikawa. [Long-acting carteolol hydrochloride 2\% ophthalmic solution phase IV study--investigation of the effectiveness, safety and plasma concentration].
Nippon Ganka Gakkai zasshi.
2010 Nov; 114(11):976-82. doi:
NULL. [PMID: 21141077] - Kwou-Yeung Wu, Cheng-Hsien Chang, Hwei-Zu Wang, Show-Jen Hong. Mechanism of carteolol-induced cytosolic Ca2+ mobilization in cultured vascular smooth muscle cells.
Vascular pharmacology.
2010 Sep; 53(3-4):88-93. doi:
10.1016/j.vph.2010.04.003. [PMID: 20416399] - Li Zhang, Xiaoli Su, Chenggong Zhang, Li Ouyang, Qingji Xie, Ming Ma, Shouzhuo Yao. Extraction and preconcentration of beta-blockers in human urine for analysis with high performance liquid chromatography by means of carrier-mediated liquid phase microextraction.
Talanta.
2010 Aug; 82(3):984-92. doi:
10.1016/j.talanta.2010.06.003. [PMID: 20678656] - E Pujos, C Cren-Olivé, O Paisse, M M Flament-Waton, M F Grenier-Loustalot. Comparison of the analysis of beta-blockers by different techniques.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Dec; 877(31):4007-14. doi:
10.1016/j.jchromb.2009.10.014. [PMID: 19879818] - Takahiro Horinouchi, Shigeru Morishima, Yoshio Tanaka, Katsuo Koike, Soichi Miwa, Ikunobu Muramatsu. Pharmacological evaluation of ocular beta-adrenoceptors in rabbit by tissue segment binding method.
Life sciences.
2009 Jan; 84(5-6):181-7. doi:
10.1016/j.lfs.2008.11.016. [PMID: 19087880] - Lu Huang, Jin-Ming Lin, Lishuang Yu, Liangjun Xu, Guonan Chen. Field-amplified on-line sample stacking for simultaneous enantioseparation and determination of some beta-blockers using capillary electrophoresis.
Electrophoresis.
2008 Sep; 29(17):3588-94. doi:
10.1002/elps.200700811. [PMID: 18803220] - Liangmin Shangguan, Wei Liu, Xiangyang Zheng, Lan Zhang. [Screening, quantification and confirmation of beta-blockers in urine using gas chromatography-mass spectrometry].
Se pu = Chinese journal of chromatography.
2008 Jul; 26(4):460-4. doi:
NULL. [PMID: 18959242] - Masayo Higashiyama, Tetsuya Tajika, Katsuhiro Inada, Akira Ohtori. Improvement of the ocular bioavailability of carteolol by ion pair.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2006 Oct; 22(5):333-9. doi:
10.1089/jop.2006.22.333. [PMID: 17076627] - Kwou-Yeung Wu, Hwei-Zu Wang, Show-Jen Hong. Effects of antiglaucoma drugs on cellular proliferation in cultured human corneal keratocytes.
The Kaohsiung journal of medical sciences.
2006 Mar; 22(3):120-5. doi:
10.1016/s1607-551x(09)70231-1. [PMID: 16602276] - P Renard, J L Kovalski, I Cochereau, S Jaulerry, W Williamson, P P Elena, M Lablache Combier, C Allaire, R Siou-Mermet. Comparison of carteolol plasmatic levels after repeated instillations of long-acting and regular formulations of carteolol 2\% in glaucoma patients.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
2005 Dec; 243(12):1221-7. doi:
10.1007/s00417-005-0024-5. [PMID: 16003515] - Hans H Maurer, Oliver Tenberken, Carsten Kratzsch, Armin A Weber, Frank T Peters. Screening for library-assisted identification and fully validated quantification of 22 beta-blockers in blood plasma by liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization.
Journal of chromatography. A.
2004 Nov; 1058(1-2):169-81. doi:
. [PMID: 15595665] - Magali Delamoye, Charlotte Duverneuil, François Paraire, Philippe de Mazancourt, Jean-Claude Alvarez. Simultaneous determination of thirteen beta-blockers and one metabolite by gradient high-performance liquid chromatography with photodiode-array UV detection.
Forensic science international.
2004 Apr; 141(1):23-31. doi:
10.1016/j.forsciint.2003.12.008. [PMID: 15066710] - Kenji Inoue, Kazuko Okugawa, Satoshi Kato, Yuji Inoue, Goji Tomita, Tetsuro Oshika, Shiro Amano. Ocular factors relevant to anti-glaucomatous eyedrop-related keratoepitheliopathy.
Journal of glaucoma.
2003 Dec; 12(6):480-5. doi:
10.1097/00061198-200312000-00007. [PMID: 14646683] - José Melena, Neville N Osborne. Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
2003 Oct; 241(10):827-33. doi:
10.1007/s00417-003-0726-5. [PMID: 12898280] - Catherine Blondin, Pascale Hamard, Béatrice Cholley, Nicole Haeffner-Cavaillon, Christophe Baudouin. In vitro effects of preserved or preservative-free antiglaucoma medications on human complement system.
Current eye research.
2003 Oct; 27(4):253-9. doi:
10.1076/ceyr.27.4.253.16603. [PMID: 14562177] - Kiyoshi Ishii, Hiroshi Matsuo, Yasuhiro Fukaya, Sumiyoshi Tanaka, Hideyuki Sakaki, Mitsunori Waki, Makoto Araie. Iganidipine, a new water-soluble Ca2+ antagonist: ocular and periocular penetration after instillation.
Investigative ophthalmology & visual science.
2003 Mar; 44(3):1169-77. doi:
10.1167/iovs.02-0482. [PMID: 12601046] - Yoko Ishii, Koichi Nakamura, Shunji Matsuki, Naoto Uemura, Ryoko Muraguchi, Mikiko Nakagawa, Shigeyuki Nakano, Kazuo Nakatsuka. Pharmacokinetic and pharmacodynamic differences between ocular and nasal instillation of carteolol on intraocular pressure and heart rate in Japanese men with high CYP2D6 activity.
Journal of clinical pharmacology.
2002 Sep; 42(9):1020-6. doi:
. [PMID: 12211218] - Shigeaki Kurita, Hiroyuki Tanaka, Michiyoshi Sanuki, Masashi Kawamoto, Osafumi Yuge. [Severe hypotension after removal of pheochromocytoma in a pediatric patient].
Masui. The Japanese journal of anesthesiology.
2002 Mar; 51(3):255-60. doi:
NULL. [PMID: 11925888] - B Washington, K Butler, A A Doye, M Jang, R J Hajjar, J K Gwathmey. Heart function challenged with beta-receptor agonism or antagonism in a heart failure model.
Cardiovascular drugs and therapy.
2001 Nov; 15(6):479-86. doi:
10.1023/a:1013755402109. [PMID: 11916356] - G E Mirza, S Karaküçük, E Temel. Comparison of the effects of 0.5\% timolol maleate, 2\% carteolol hydrochloride, and 0.3\% metipranolol on intraocular pressure and perimetry findings and evaluation of their ocular and systemic effects.
Journal of glaucoma.
2000 Feb; 9(1):45-50. doi:
10.1097/00061198-200002000-00009. [PMID: 10708231] - J D Bartlett, M Olivier, T Richardson, R Whitaker, D Pensyl, M R Wilson. Central nervous system and plasma lipid profiles associated with carteolol and timolol in postmenopausal black women.
Journal of glaucoma.
1999 Dec; 8(6):388-95. doi:
. [PMID: 10604299] - T Sugiyama, I Azuma, M Araie, S Fujisawa, H Urashima, M Nagasawa. Effect of continuous intravenous infusion of carteolol chloride on tissue blood flow in rabbit optic nerve head.
Japanese journal of ophthalmology.
1999 Nov; 43(6):490-4. doi:
10.1016/s0021-5155(99)00107-0. [PMID: 10672877] - S Isawa, M Murasaki, S Miura, M Yoshioka, M Uchiumi, Y Kumagai, S Aoki, H Hisazumi, S Kudo. Pharmacokinetic and pharmacodynamic interactions among haloperidol, carteolol hydrochloride and biperiden hydrochloride.
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology.
1999 Jul; 19(3):111-8. doi:
NULL. [PMID: 10495985] - W C Stewart, H B Dubiner, T K Mundorf, R A Laibovitz, K N Sall, L J Katz, K Singh, D G Shulman, L I Siegel, A C Hudgins, L Nussbaum, M Apostolaros. Effects of carteolol and timolol on plasma lipid profiles in older women with ocular hypertension or primary open-angle glaucoma.
American journal of ophthalmology.
1999 Feb; 127(2):142-7. doi:
10.1016/s0002-9394(98)00328-6. [PMID: 10030554] - T Sugiyama, I Azuma, M Araie, S Fujisawa, H Urashima, M Nagasawa. [The effect of continuous and intravenous application of carteolol chloride on tissue blood flow in the rabbit optic nerve head].
Nippon Ganka Gakkai zasshi.
1998 Oct; 102(10):662-6. doi:
NULL. [PMID: 9834608] - B Takase, H Hikita, A Uehata, K Satomura, A Kurita, H Nakamura. Effect of carteolol on silent myocardial ischemia, variability in heart rate, and the pain-modulating system.
American heart journal.
1997 Nov; 134(5 Pt 1):945-54. doi:
10.1016/s0002-8703(97)80019-1. [PMID: 9398108] - Y Tamaki, M Araie, K Tomita, M Nagahara, A Tomidokoro. Effect of topical beta-blockers on tissue blood flow in the human optic nerve head.
Current eye research.
1997 Nov; 16(11):1102-10. doi:
10.1076/ceyr.16.11.1102.5101. [PMID: 9395769] - S Kudo, K Umehara, Y Abe, M Furukawa, M Odomi. Intracerebral penetration of carteolol hydrochloride in rats.
Psychopharmacology.
1997 Jun; 131(4):388-93. doi:
10.1007/s002130050307. [PMID: 9226741] - Y Saitoh, T Tani, Y Asahi, Z Man, K Kawano, H Ikunaga. Improving effect of carteolol on bodyweight and carbohydrate and lipid metabolic responses in the OLETF rat.
Clinical and experimental pharmacology & physiology.
1997 May; 24(5):321-5. doi:
10.1111/j.1440-1681.1997.tb01195.x. [PMID: 9143781] - T Yamamoto, Y Kitazawa, A Noma, S Maeda, A Kato, Y Ando, T Ido, K Inazumi, T Hayakawa, Y Goto, M Ichien. The effects of the beta-adrenergic-blocking agents, timolol and carteolol, on plasma lipids and lipoproteins in Japanese glaucoma patients.
Journal of glaucoma.
1996 Aug; 5(4):252-7. doi:
NULL. [PMID: 8795770] - T Yoshikawa, S Handa, T Anzai, H Nishimura, A Baba, M Akaishi, H Mitamura, S Ogawa. Early reduction of neurohumoral factors plays a key role in mediating the efficacy of beta-blocker therapy for congestive heart failure.
American heart journal.
1996 Feb; 131(2):329-36. doi:
10.1016/s0002-8703(96)90362-2. [PMID: 8579029] - Y Tamaki, K Tomita, M Araie, A Tomidokoro, M Nagahara. [Effect of topical adrenergic agents on tissue circulation in human optic nerve head evaluated with a laser speckle microcirculation analyser].
Nippon Ganka Gakkai zasshi.
1996 Jan; 100(1):55-62. doi:
. [PMID: 8644530] - M Nagasawa, M Kashimoto, M Sugawara, Y Kimura. Determination of the beta-blocker carteolol in human plasma by a sensitive gas chromatographic-negative-ion chemical ionization high-resolution mass spectrometric method.
Journal of chromatography. B, Biomedical applications.
1995 Nov; 673(2):294-8. doi:
10.1016/0378-4347(95)00278-7. [PMID: 8611964] - H Takahashi, K Nakano, T Yasuda, Y Komiyama, T Murakami, M Nishimura, T Nakanishi, M Sakamoto, A Nanbu, M Yoshimura. Anti-obesity and anti-diabetic effects of carteolol in non-insulin-dependent diabetic mice.
Clinical and experimental pharmacology & physiology.
1994 Jun; 21(6):477-83. doi:
10.1111/j.1440-1681.1994.tb02544.x. [PMID: 7982278] - A B Safran, F Simona, A Sansonetti, D Pometta, R James. Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level.
American journal of ophthalmology.
1994 May; 117(5):683. doi:
10.1016/s0002-9394(14)70091-1. [PMID: 8172288] - S F Freedman, N J Freedman, M B Shields, B Lobaugh, G P Samsa, E U Keates, A Ollie. Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level.
American journal of ophthalmology.
1993 Nov; 116(5):600-11. doi:
10.1016/s0002-9394(14)73203-9. [PMID: 8238221] - U Weber, L Michaelis. [The effect of carteolol. Prolonged and increased effect by liposome suspension].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.
1992 Dec; 89(6):449-51. doi:
". [PMID: 1486258] - M Amemiya, K Tabei, H Furuya, Y Sakairi, Y Asano. Pharmacokinetics of carteolol in patients with impaired renal function.
European journal of clinical pharmacology.
1992; 43(4):417-21. doi:
10.1007/bf02220619. [PMID: 1451723] - W Krümke, A Mader, H Michael, B M Giannetti, W Hollmann. An examination of the hemodynamic and metabolic effects of carteolol during different workloads on a bicycle ergometer.
International journal of sports medicine.
1991 Dec; 12(6):548-56. doi:
10.1055/s-2007-1024732. [PMID: 1797696] - H Saxenhofer, D Morger, P Weidmann, C Ferrier, S G Shaw. Modulation of noradrenergic but not angiotensinergic blood pressure control by beta-blockade with carteolol.
Journal of hypertension.
1991 Nov; 9(11):1049-56. doi:
10.1097/00004872-199111000-00011. [PMID: 1661763] - M Kohno, K Yokokawa, K Yasunari, K Murakawa, N Kurihara, T Takeda. Acute effects of alpha- and beta-adrenoceptor blockade on plasma atrial natriuretic peptides during exercise in elderly patients with mild hypertension.
Chest.
1991 Apr; 99(4):847-54. doi:
10.1378/chest.99.4.847. [PMID: 1826253] - K Hasui, T Ohmoto, T Tamaki, K Fukui, H Iwao, Y Abe. Effects of prolonged treatment with beta-adrenoceptor antagonist, carteolol on systemic and regional hemodynamics in stroke-prone spontaneously hypertensive rats.
Journal of pharmacobio-dynamics.
1991 Feb; 14(2):94-100. doi:
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Clinical science (London, England : 1979).
1990 Dec; 79(6):613-8. doi:
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Endocrinologia japonica.
1990 Aug; 37(4):471-8. doi:
10.1507/endocrj1954.37.471. [PMID: 1707360] - K Shimada, A Kawamoto, K Matsubayashi, T Chikamori, O Kuzume, T Ozawa. Effects of long-term treatment with low doses of carteolol on cardiovascular regulatory functions in elderly patients with mild hypertension.
Clinical therapeutics.
1990 Mar; 12(2):118-24. doi:
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Journal of pharmacobio-dynamics.
1990 Jan; 13(1):64-9. doi:
10.1248/bpb1978.13.64. [PMID: 1971305] - T Baba, S Murabayashi, T Tomiyama, K Takebe. Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension.
European journal of clinical pharmacology.
1990; 38(3):305-7. doi:
10.1007/bf00315037. [PMID: 2187701] - K Tabei, H Furuya, Y Asano, S Hosoda. Effect of carteolol on renal function in healthy subjects and patients with hypertension.
European journal of clinical pharmacology.
1989; 36(1):83-6. doi:
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Journal of cardiovascular pharmacology.
1987 Dec; 10(6):667-74. doi:
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British journal of clinical pharmacology.
1987 Mar; 23(3):339-43. doi:
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The Tohoku journal of experimental medicine.
1985 Aug; 146(4):385-90. doi:
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Journal of cardiovascular pharmacology.
1985 Jul; 7(4):805-8. doi:
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Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1985 May; 105(5):459-63. doi:
10.1248/yakushi1947.105.5_459. [PMID: 4032235] - R Katori, M Tashi, M Ohno, T Oogai, M Morishita, S Morii. Effects of long use of a beta-blocker, carteolol, on exercise hemodynamics in hypertensives.
Japanese circulation journal.
1985 Jan; 49(1):52-60. doi:
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European journal of clinical pharmacology.
1985; 29(4):461-5. doi:
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Clinical pharmacology and therapeutics.
1984 Mar; 35(3):301-6. doi:
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European journal of clinical pharmacology.
1984; 27(5):545-53. doi:
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European journal of clinical pharmacology.
1983; 25(6):749-57. doi:
10.1007/bf00542514. [PMID: 6141053] - T Ishizaki, A Ohnishi, T Sasaki, K Kushida, Y Horai, K Chiba, T Suganuma. Pharmacokinetics and absolute bioavailability of carteolol, a new beta-adrenergic receptor blocking agent.
European journal of clinical pharmacology.
1983; 25(1):95-101. doi:
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