Zeranol (BioDeep_00000406064)
Main id: BioDeep_00000002605
natural product PANOMIX_OTCML-2023 Volatile Flavor Compounds
代谢物信息卡片
alpha-Zearalanol
化学式: C18H26O5 (322.1780146)
中文名称: 乙腈中α-玉米赤霉醇溶液标准物质, 折仑诺
谱图信息:
最多检出来源 Viridiplantae(plant) 12.5%
分子结构信息
SMILES: CC1CCCC(CCCCCC2=C(C(=CC(=C2)O)O)C(=O)O1)O
InChI: InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
Same as: D06362
CONFIDENCE Reference Standard (Level 1)
同义名列表
3 个代谢物同义名
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:35064
- KEGG: C14752
- KEGGdrug: D06362
- PubChem: 2999413
- DrugBank: DB11478
- ChEMBL: CHEMBL450613
- MeSH: Zeranol
- CAS: 26538-44-3
- MoNA: PM006303
- MoNA: AC000646
- MoNA: AC000645
- MoNA: AC000644
- MoNA: AC000643
- MoNA: AC000642
- MoNA: FiehnHILIC003059
- MoNA: FiehnHILIC001585
- MoNA: FiehnHILIC000867
- PubChem: 17395750
- PDB-CCD: 27J
- NIKKAJI: J10.434E
- KNApSAcK: 35064
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Honglei Qu, Yunduo Zheng, Ruifen Kang, Yulong Feng, Pengshuai Li, Yantao Wang, Jie Cheng, Cheng Ji, Wenqiong Chai, Qiugang Ma. Toxicokinetics of Zearalenone following Oral Administration in Female Dezhou Donkeys.
Toxins.
2024 Jan; 16(1):. doi:
10.3390/toxins16010051. [PMID: 38251267] - Yanrong Su, Julia Santucci-Pereira, Nhi M Dang, Joice Kanefsky, Vishnuprabha Rahulkannan, Meardey Hillegass, Shalina Joshi, Hafsa Gurdogan, Zhen Chen, Vincent Bessonneau, Ruthann Rudel, Jennifer Ser-Dolansky, Sallie S Schneider, Jose Russo. Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats.
International journal of molecular sciences.
2022 Jan; 23(3):. doi:
10.3390/ijms23031398. [PMID: 35163327] - Carolyn W Kinkade, Zorimar Rivera-Núñez, Ludwik Gorcyzca, Lauren M Aleksunes, Emily S Barrett. Impact of Fusarium-Derived Mycoestrogens on Female Reproduction: A Systematic Review.
Toxins.
2021 05; 13(6):. doi:
10.3390/toxins13060373. [PMID: 34073731] - Jennifer Duringer, Rajarshi Mazumder, Valerie Palmer, A Morrie Craig, Peter Spencer. Case-Control Study of Nodding Syndrome in Acholiland: Urinary Multi-Mycotoxin Screening.
Toxins.
2021 04; 13(5):. doi:
10.3390/toxins13050313. [PMID: 33925470] - Ana Juan-García, Giovanni Caprioli, Gianni Sagratini, Jordi Mañes, Cristina Juan. Coffee Silverskin and Spent Coffee Suitable as Neuroprotectors against Cell Death by Beauvericin and α-Zearalenol: Evaluating Strategies of Treatment.
Toxins.
2021 02; 13(2):. doi:
10.3390/toxins13020132. [PMID: 33579040] - Tim Birr, Tolke Jensen, Nils Preußke, Frank D Sönnichsen, Marthe De Boevre, Sarah De Saeger, Mario Hasler, Joseph-Alexander Verreet, Holger Klink. Occurrence of Fusarium Mycotoxins and Their Modified Forms in Forage Maize Cultivars.
Toxins.
2021 02; 13(2):. doi:
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Toxins.
2021 01; 13(2):. doi:
10.3390/toxins13020084. [PMID: 33499402] - Yan Qin Tan, Qing Li, Lin Wang, Leo C Chiu-Leung, Lai K Leung. The livestock growth-promoter zeranol facilitates GLUT4 translocation in 3T3 L1 adipocytes.
Chemosphere.
2020 Aug; 253(?):126772. doi:
10.1016/j.chemosphere.2020.126772. [PMID: 32464760] - Shupeng Yang, Yanshen Li, Marthe De Boevre, Sarah De Saeger, Jinhui Zhou, Yi Li, Huiyan Zhang, Feifei Sun. Toxicokinetics of α-zearalenol and its masked form in rats and the comparative biotransformation in liver microsomes from different livestock and humans.
Journal of hazardous materials.
2020 Jul; 393(?):121403. doi:
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Toxicology letters.
2020 Jun; 326(?):52-60. doi:
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Journal of agricultural and food chemistry.
2020 Jan; 68(1):351-357. doi:
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Scientific reports.
2019 10; 9(1):14214. doi:
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Food additives & contaminants. Part B, Surveillance.
2019 Jun; 12(2):105-115. doi:
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Journal of agricultural and food chemistry.
2019 Mar; 67(12):3448-3458. doi:
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Environmental health : a global access science source.
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2019 Mar; 43(2):126-133. doi:
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Archives of toxicology.
2018 08; 92(8):2691-2700. doi:
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2018 Jul; 47(4):615-620. doi:
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Metabolomics : Official journal of the Metabolomic Society.
2018 02; 14(3):33. doi:
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2018 Feb; 53(1):68-73. doi:
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2017 04; 61(4):. doi:
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Toxins.
2017 02; 9(2):. doi:
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Environmental science and pollution research international.
2016 Aug; 23(15):15504-14. doi:
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Journal of animal science.
2016 Jul; 94(7):3051-60. doi:
10.2527/jas.2016-0470. [PMID: 27482692] - Shaohui Zong, Gaofeng Zeng, Ye Fang, Jinzhen Peng, Bin Zou, Taihang Gao, Jingmin Zhao. The effects of α-zearalanol on the proliferation of bone-marrow-derived mesenchymal stem cells and their differentiation into osteoblasts.
Journal of bone and mineral metabolism.
2016 Mar; 34(2):151-60. doi:
10.1007/s00774-015-0659-1. [PMID: 25944420] - Dudu Demir, Nahit Gencer, Oktay Arslan. An alternative purification method for human serum paraoxonase 1 and its interactions with anabolic compounds.
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Environmental toxicology and chemistry.
2015 Dec; 34(12):2906-13. doi:
10.1002/etc.3166. [PMID: 26184466] - Urara Nakamura, Hiroya Kadokawa. The nonsteroidal mycoestrogen zearalenone and its five metabolites suppress LH secretion from the bovine anterior pituitary cells via the estradiol receptor GPR30 in vitro.
Theriogenology.
2015 Nov; 84(8):1342-9. doi:
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Environmental toxicology and pharmacology.
2015 Nov; 40(3):722-8. doi:
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Toxins.
2015 Aug; 7(9):3465-80. doi:
10.3390/toxins7093465. [PMID: 26343724] - Maxim A Yunin, Pavel S Metalnikov, Alexander A Komarov, Alexander N Panin. Development of a rapid method for the analysis of trenbolone, nortestosterone, and zeranol in bovine liver using liquid chromatography tandem mass spectrometry.
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2015 Jun; 407(15):4363-71. doi:
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2014 Dec; 68(6):492-506. doi:
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Molecular nutrition & food research.
2014 Dec; 58(12):2358-68. doi:
10.1002/mnfr.201400406. [PMID: 25243722] - Matías Regiart, Sirley V Pereira, Viviana G Spotorno, Franco A Bertolino, Julio Raba. Food safety control of zeranol through voltammetric immunosensing on Au-Pt bimetallic nanoparticle surfaces.
The Analyst.
2014 Sep; 139(18):4702-9. doi:
10.1039/c4an00686k. [PMID: 25057514] - Juan M Echarte, Damián C Fernández, Carlos A Chiacchio, Verónica M Torres Leedham. Comparison of a Validated LC/MS/MS Method with a Validated GC/MS Method for the Analysis of Zeranol and its Related Mycotoxin Residues in Bovine Urine Samples Collected During Argentina's Residue Monitoring Control Program (2005-2012).
Journal of AOAC International.
2014 Sep; 97(5):1470-5. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Jul; 962(?):68-74. doi:
10.1016/j.jchromb.2014.05.019. [PMID: 24907545] - Yilong Dong, Aimei Jiang, Hongju Yang, Huicheng Chen, Yanmei Wang. Phytoestrogen α-zearalanol improves memory impairment and hippocampal neurogenesis in ovariectomized mice.
TheScientificWorldJournal.
2014; 2014(?):862019. doi:
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BioMed research international.
2014; 2014(?):143192. doi:
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PloS one.
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2013 Jul; 57-58(?):50-9. doi:
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Toxicology letters.
2013 Jun; 219(3):218-22. doi:
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Biosensors & bioelectronics.
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The Analyst.
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European journal of pharmacology.
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The Science of the total environment.
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Drug testing and analysis.
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Analytical and bioanalytical chemistry.
2011 Nov; 401(9):2831-41. doi:
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Toxicology letters.
2011 Oct; 206(2):210-7. doi:
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Journal of molecular recognition : JMR.
2011 Sep; 24(5):815-23. doi:
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International journal of oncology.
2011 Apr; 38(4):985-92. doi:
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Atherosclerosis.
2011 Apr; 215(2):309-15. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Feb; 879(5-6):411-20. doi:
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Anticancer research.
2011 Feb; 31(2):481-6. doi:
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Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2010 Nov; 27(11):1558-65. doi:
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The Journal of veterinary medical science.
2010 Mar; 72(3):307-12. doi:
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Journal of biochemical and molecular toxicology.
2009 Jul; 23(4):233-43. doi:
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Analytica chimica acta.
2009 Apr; 637(1-2):47-54. doi:
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Toxicology.
2008 Oct; 252(1-3):72-7. doi:
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Animal reproduction science.
2008 Aug; 107(1-2):115-30. doi:
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The Journal of pediatrics.
2008 May; 152(5):690-5, 695.e1. doi:
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Journal of Zhejiang University. Science. B.
2007 Dec; 8(12):900-5. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2007 Nov; 24(3-4):381-7. doi:
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Animal reproduction science.
2007 Jun; 99(3-4):408-12. doi:
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Journal of chromatography. A.
2007 Jan; 1138(1-2):132-40. doi:
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Veterinary research communications.
2006 May; 30(4):445-53. doi:
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Analytical and bioanalytical chemistry.
2006 Mar; 384(5):1221-7. doi:
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Journal of natural products.
2006 Feb; 69(2):178-84. doi:
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Journal of animal physiology and animal nutrition.
2005 Aug; 89(7-8):268-76. doi:
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Applied microbiology and biotechnology.
2005 Jun; 67(6):838-44. doi:
10.1007/s00253-004-1816-y. [PMID: 15630583] - Stefanie Weber, Prisca Leuschner, Peter Kämpfer, Wolfgang Dott, Juliane Hollender. Degradation of estradiol and ethinyl estradiol by activated sludge and by a defined mixed culture.
Applied microbiology and biotechnology.
2005 Apr; 67(1):106-12. doi:
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Polish journal of veterinary sciences.
2005; 8(3):209-18. doi:
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Endocrine.
2004 Dec; 25(3):235-45. doi:
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Endocrine.
2004 Nov; 25(2):117-9. doi:
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Endocrine.
2004 Nov; 25(2):121-9. doi:
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Food additives and contaminants.
2004 Sep; 21(9):833-9. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2004 Aug; 18(4):467-74. doi:
10.1016/j.tiv.2003.12.011. [PMID: 15130604] - Wen Wang, Guang-jin Zhu, Shu-Yu Zu. Effects of 17beta-estradiol and phytoestrogen alpha-zearalanol on tissue factor in plasma of ovariectomized rats and HUVECs.
The Chinese journal of physiology.
2004 Jun; 47(2):67-72. doi:
NULL. [PMID: 15481788] - Suling Liu, Yasuro Sugimoto, Claudio Sorio, Cristina Tecchio, Young C Lin. Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7.
Oncogene.
2004 Feb; 23(6):1256-62. doi:
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Food additives and contaminants.
2004 Jan; 21(1):52-62. doi:
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Food additives and contaminants.
2003 Sep; 20(9):804-12. doi:
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Journal of AOAC International.
2003 Jul; 86(4):631-9. doi:
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Magnesium research.
2003 Jun; 16(2):106-10. doi:
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Domestic animal endocrinology.
2003 Apr; 24(3):243-55. doi:
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Human reproduction (Oxford, England).
2003 Mar; 18(3):487-94. doi:
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British poultry science.
2003 Mar; 44(1):113-26. doi:
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Journal of animal science.
2003 Jan; 81(1):135-42. doi:
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Food additives and contaminants.
2002 Dec; 19(12):1130-7. doi:
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Journal of agricultural and food chemistry.
2002 Aug; 50(17):4769-76. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2002 Aug; 32(8):641-51. doi:
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Journal of AOAC International.
2002 Jul; 85(4):841-7. doi:
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Journal of animal science.
2002 Jun; 80(6):1433-41. doi:
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