Desaminotyrosine (BioDeep_00000405517)
Main id: BioDeep_00000001224
PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
化学式: C9H10O3 (166.063)
中文名称: 对羟基苯丙酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C=CC(=C1)O)CCC(O)=O
InChI: InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)
描述信息
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:32980
- KEGG: C01744
- PubChem: 10394
- DrugBank: DB03897
- ChEMBL: CHEMBL1172560
- CAS: 501-97-3
- MoNA: HMDB0002199_ms_ms_2025
- MoNA: HMDB0002199_ms_ms_2026
- MoNA: HMDB0002199_ms_ms_2027
- ChEBI: CHEBI:16331
- PubChem: 4878
- KNApSAcK: C00029471
- PDB-CCD: HPP
- 3DMET: B00339
- NIKKAJI: J1.565B
- RefMet: Desaminotyrosine
- medchemexpress: HY-W015346
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-978
- KNApSAcK: 16331
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
26 个相关的物种来源信息
- 1080010 - Aloe africana: 10.1021/JF071110T
- 95948 - Anigozanthos preissii:
- 49314 - Annona cherimola:
- 210954 - Bulbine frutescens: 10.1002/CHEM.200701328
- 4442 - Camellia sinensis: 10.1016/S0731-7085(00)00272-7
- 142762 - Cestrum parqui: 10.1021/JF049847V
- 1640932 - Chenopodium formosanum: 10.1002/PCA.924
- 1222053 - Cinnamomum reticulatum:
- 1094085 - Colchicum kotschyi: 10.1016/0031-9422(90)87143-I
- 3663 - Cucurbita pepo: 10.1016/0031-9422(82)83018-5
- 1928361 - Cytospora ceratosperma: 10.1271/BBB1961.46.2101
- 1508135 - Dendrobium plicatile: 10.1248/CPB.41.1346
- 3311 - Ginkgo biloba: 10.1016/S0731-7085(00)00272-7
- 215659 - Hornstedtia reticulata:
- 597310 - Iryanthera sagotiana: 10.1016/S0031-9422(97)00306-3
- 699669 - Lepisorus contortus: 10.1021/NP100373F
- 3750 - Malus domestica: 10.1016/0308-8146(92)90223-O
- 283210 - Malus pumila: 10.1016/0308-8146(92)90223-O
- 145754 - Malva sylvestris: 10.1016/J.PHYTOCHEM.2005.11.023
- 4146 - Olea europaea: 10.1016/B978-0-12-374420-3.00099-1
- 3435 - Persea americana: 10.1007/S11418-006-0122-7
- 3330 - Picea glauca: 10.1016/S0031-9422(96)00388-3
- 150529 - Polyscias murrayi: 10.1016/J.PHYTOCHEM.2004.12.022
- 117406 - Spiranthes sinensis: 10.1248/CPB.49.1098
- 126265 - Spiranthes vernalis: 10.1248/CPB.49.1098
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Qianwen Wang, Zhifeng Fang, Yue Xiao, Hongchao Wang, Pinghu Zhang, Wenwei Lu, Hao Zhang, Xiuwen Zhou. Lactiplantibacillus pentoses CCFM1227 Produces Desaminotyrosine to Protect against Influenza Virus H1N1 Infection through the Type I Interferon in Mice.
Nutrients.
2023 Aug; 15(16):. doi:
10.3390/nu15163659
. [PMID: 37630849] - Ibrahim E Sallam, Ulrike Rolle-Kampczyk, Stephanie Serena Schäpe, Soumaya S Zaghloul, Riham S El-Dine, Ping Shao, Martin von Bergen, Mohamed A Farag. Evaluation of Antioxidant Activity and Biotransformation of Opuntia Ficus Fruit: The Effect of In Vitro and Ex Vivo Gut Microbiota Metabolism.
Molecules (Basel, Switzerland).
2022 Nov; 27(21):. doi:
10.3390/molecules27217568
. [PMID: 36364395] - Samar Rezq, Mona F Mahmoud, Assem M El-Shazly, Mohamed A El Raey, Mansour Sobeh. Anti-Inflammatory, Antipyretic, and Analgesic Properties of Potamogeton perfoliatus Extract: In Vitro and In Vivo Study.
Molecules (Basel, Switzerland).
2021 Aug; 26(16):. doi:
10.3390/molecules26164826
. [PMID: 34443414] - Feng Li, Liping Wang, Yilei Cai, Yihuo Luo, Xianai Shi. Safety assessment of desaminotyrosine: Acute, subchronic oral toxicity, and its effects on intestinal microbiota in rats.
Toxicology and applied pharmacology.
2021 04; 417(?):115464. doi:
10.1016/j.taap.2021.115464
. [PMID: 33636197] - Xianyu Liang, Fan Liu, Yiqun Wan, Xiaoying Yin, Weiting Liu. Facile synthesis of molecularly imprinted polymers for selective extraction of tyrosine metabolites in human urine.
Journal of chromatography. A.
2019 Feb; 1587(?):34-41. doi:
10.1016/j.chroma.2018.12.014
. [PMID: 30551942] - Mark Levisson, Constantinos Patinios, Sascha Hein, Philip A de Groot, Jean-Marc Daran, Robert D Hall, Stefan Martens, Jules Beekwilder. Engineering de novo anthocyanin production in Saccharomyces cerevisiae.
Microbial cell factories.
2018 Jul; 17(1):103. doi:
10.1186/s12934-018-0951-6
. [PMID: 29970082] - Weiqun Lin, Wenting Wang, Hai Yang, Dongliang Wang, Wenhua Ling. Influence of Intestinal Microbiota on the Catabolism of Flavonoids in Mice.
Journal of food science.
2016 Dec; 81(12):H3026-H3034. doi:
10.1111/1750-3841.13544
. [PMID: 27792839] - Wei Zou, Yulong Luo, Menghua Liu, Si Chen, Sheng Wang, Yichu Nie, Guohua Cheng, Weiwei Su, Kejian Zhang. Human intestinal microbial metabolism of naringin.
European journal of drug metabolism and pharmacokinetics.
2015 Sep; 40(3):363-7. doi:
10.1007/s13318-014-0193-x
. [PMID: 24935725] - Claudia Axel, Bettina Röcker, Brid Brosnan, Emanuele Zannini, Ambrose Furey, Aidan Coffey, Elke K Arendt. Application of Lactobacillus amylovorus DSM19280 in gluten-free sourdough bread to improve the microbial shelf life.
Food microbiology.
2015 May; 47(?):36-44. doi:
10.1016/j.fm.2014.10.005
. [PMID: 25583336] - Zehra Can, Barbaros Dincer, Huseyin Sahin, Nimet Baltas, Oktay Yildiz, Sevgi Kolayli. Polyphenol oxidase activity and antioxidant properties of Yomra apple (Malus communis L.) from Turkey.
Journal of enzyme inhibition and medicinal chemistry.
2014 Dec; 29(6):829-35. doi:
10.3109/14756366.2013.858144
. [PMID: 24246090] - Kathleen Trautwein, Heinz Wilkes, Ralf Rabus. Proteogenomic evidence for β-oxidation of plant-derived 3-phenylpropanoids in "Aromatoleum aromaticum" EbN1.
Proteomics.
2012 May; 12(9):1402-13. doi:
10.1002/pmic.201100279
. [PMID: 22589189] - Xiaoyu Fan, Haitao Li, Jie Zhao, Fanbo Lin, Lingli Zhang, Youyu Zhang, Shouzhuo Yao. A novel label-free fluorescent sensor for the detection of potassium ion based on DNAzyme.
Talanta.
2012 Jan; 89(?):57-62. doi:
10.1016/j.talanta.2011.11.056
. [PMID: 22284459] - Mijin Kim, Sang Mi An, Jae-Sook Koh, Dong-Il Jang, Yong Chool Boo. Use of non-melanocytic HEK293 cells stably expressing human tyrosinase for the screening of anti-melanogenic agents.
Journal of cosmetic science.
2011 Sep; 62(5):515-23. doi:
. [PMID: 22152495]
- Jian-Hong Yang, Tamara P Kondratyuk, Katherine C Jermihov, Laura E Marler, Xi Qiu, Yongsoo Choi, Hongmei Cao, Rui Yu, Megan Sturdy, Rong Huang, Ying Liu, Li-Qin Wang, Andrew D Mesecar, Richard B van Breemen, John M Pezzuto, Harry H S Fong, Ye-Gao Chen, Hong-Jie Zhang. Bioactive compounds from the fern Lepisorus contortus.
Journal of natural products.
2011 Feb; 74(2):129-36. doi:
10.1021/np100373f
. [PMID: 21261296] - Annett Braune, Michael Blaut. Deglycosylation of puerarin and other aromatic C-glucosides by a newly isolated human intestinal bacterium.
Environmental microbiology.
2011 Feb; 13(2):482-94. doi:
10.1111/j.1462-2920.2010.02352.x
. [PMID: 20946528] - Maja Jakesevic, Kjersti Aaby, Grethe-Iren A Borge, Bengt Jeppsson, Siv Ahrné, Göran Molin. Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion.
BMC complementary and alternative medicine.
2011 Jan; 11(?):8. doi:
10.1186/1472-6882-11-8
. [PMID: 21272305] - Chris I R Gill, Gordon J McDougall, Sheila Glidewell, Derek Stewart, Qing Shen, Kieran Tuohy, Aine Dobbin, Adele Boyd, Emma Brown, Sumanto Haldar, Ian R Rowland. Profiling of phenols in human fecal water after raspberry supplementation.
Journal of agricultural and food chemistry.
2010 Oct; 58(19):10389-95. doi:
10.1021/jf1017143
. [PMID: 20809621] - Yunbao Liu, Muraleedharan G Nair. An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
Journal of natural products.
2010 Jul; 73(7):1193-5. doi:
10.1021/np1000945
. [PMID: 20565070] - D Kridelbaugh, S Hughes, T Allen, K C Doerner. Production of 4-ethylphenol from 4-hydroxycinnamic acid by Lactobacillus sp. isolated from a swine waste lagoon.
Journal of applied microbiology.
2010 Jul; 109(1):190-8. doi:
10.1111/j.1365-2672.2009.04642.x
. [PMID: 20028439] - Fulgencio Saura-Calixto, Jara Pérez-Jiménez, Sonia Touriño, José Serrano, Elisabet Fuguet, Josep Lluis Torres, Isabel Goñi. Proanthocyanidin metabolites associated with dietary fibre from in vitro colonic fermentation and proanthocyanidin metabolites in human plasma.
Molecular nutrition & food research.
2010 Jul; 54(7):939-46. doi:
10.1002/mnfr.200900276
. [PMID: 20087856] - Jun-Fang Wu, Elaine Holmes, Jian Xue, Shu-Hua Xiao, Burton H Singer, Hui-Ru Tang, Jürg Utzinger, Yu-Lan Wang. Metabolic alterations in the hamster co-infected with Schistosoma japonicum and Necator americanus.
International journal for parasitology.
2010 May; 40(6):695-703. doi:
10.1016/j.ijpara.2009.11.003
. [PMID: 19951707] - Philippe A Guy, Mathieu Renouf, Denis Barron, Christophe Cavin, Fabiola Dionisi, Sunil Kochhar, Serge Rezzi, Gary Williamson, Heike Steiling. Quantitative analysis of plasma caffeic and ferulic acid equivalents by liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Dec; 877(31):3965-74. doi:
10.1016/j.jchromb.2009.10.006
. [PMID: 19879819] - Akira Tokumura, Laura D Carbone, Yasuko Yoshioka, Junichi Morishige, Masaki Kikuchi, Arnold Postlethwaite, Mitchell A Watsky. Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis.
International journal of medical sciences.
2009 Jun; 6(4):168-76. doi:
10.7150/ijms.6.168
. [PMID: 19521548] - Chao-Feng Zhang, Li Shao, Wei-Hua Huang, Lei Wang, Zheng-Tao Wang, Luo-Shan Xu. [Phenolic components from herbs of Dendrobium aphyllum].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Dec; 33(24):2922-5. doi:
. [PMID: 19294851]
- S M An, S I Lee, S W Choi, S-W Moon, Y C Boo. p-Coumaric acid, a constituent of Sasa quelpaertensis Nakai, inhibits cellular melanogenesis stimulated by alpha-melanocyte stimulating hormone.
The British journal of dermatology.
2008 Aug; 159(2):292-9. doi:
10.1111/j.1365-2133.2008.08653.x
. [PMID: 18544081] - Eleni Skordi, Ivan K S Yap, Sandrine P Claus, François-Pierre J Martin, Olivier Cloarec, Johan Lindberg, Ina Schuppe-Koistinen, Elaine Holmes, Jeremy K Nicholson. Analysis of time-related metabolic fluctuations induced by ethionine in the rat.
Journal of proteome research.
2007 Dec; 6(12):4572-81. doi:
10.1021/pr070268q
. [PMID: 17966971] - Mi-Kyung Lee, Yong Bok Park, Surk-Sik Moon, Song Hae Bok, Dong-Ju Kim, Tae-Youl Ha, Tae-Sook Jeong, Kyu-Shik Jeong, Myung-Sook Choi. Hypocholesterolemic and antioxidant properties of 3-(4-hydroxyl)propanoic acid derivatives in high-cholesterol fed rats.
Chemico-biological interactions.
2007 Oct; 170(1):9-19. doi:
10.1016/j.cbi.2007.06.037
. [PMID: 17662703] - Hanna-Leena Alakomi, Riitta Puupponen-Pimiä, Anna-Marja Aura, Ilkka M Helander, Liisa Nohynek, Kirsi-Marja Oksman-Caldentey, Maria Saarela. Weakening of salmonella with selected microbial metabolites of berry-derived phenolic compounds and organic acids.
Journal of agricultural and food chemistry.
2007 May; 55(10):3905-12. doi:
10.1021/jf070190y
. [PMID: 17439151] - Yu Zhang, Xiaowei Tie, Bili Bao, Xiaoqin Wu, Ying Zhang. Metabolism of flavone C-glucosides and p-coumaric acid from antioxidant of bamboo leaves (AOB) in rats.
The British journal of nutrition.
2007 Mar; 97(3):484-94. doi:
10.1017/s0007114507336830
. [PMID: 17313710] - Seon-Min Jeon, Hae Kyung Kim, Hye-Jin Kim, Gyeong-Min Do, Tae-Sook Jeong, Yong Bok Park, Myung-Sook Choi. Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats.
Translational research : the journal of laboratory and clinical medicine.
2007 Jan; 149(1):15-21. doi:
10.1016/j.trsl.2006.08.001
. [PMID: 17196518] - Pernilla C Karlsson, Ulrika Huss, Andrew Jenner, Barry Halliwell, Lars Bohlin, Joseph J Rafter. Human fecal water inhibits COX-2 in colonic HT-29 cells: role of phenolic compounds.
The Journal of nutrition.
2005 Oct; 135(10):2343-9. doi:
10.1093/jn/135.10.2343
. [PMID: 16177193] - Andrew M Jenner, Joseph Rafter, Barry Halliwell. Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds.
Free radical biology & medicine.
2005 Mar; 38(6):763-72. doi:
10.1016/j.freeradbiomed.2004.11.020
. [PMID: 15721987] - Manal Abd El Mohsen, Joanne Marks, Gunter Kuhnle, Catherine Rice-Evans, Kevin Moore, Glenn Gibson, Edward Debnam, S Kaila Srai. The differential tissue distribution of the citrus flavanone naringenin following gastric instillation.
Free radical research.
2004 Dec; 38(12):1329-40. doi:
10.1080/10715760400017293
. [PMID: 15763957] - Kevin T Watts, Pyung Cheon Lee, Claudia Schmidt-Dannert. Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli.
Chembiochem : a European journal of chemical biology.
2004 Apr; 5(4):500-7. doi:
10.1002/cbic.200300783
. [PMID: 15185374] - Motomi Matsukawa, Toshikazu Hirai, Shoko Karita, Toshifumi Akizawa, Hidemitsu Pan-Hou, Masanori Yoshioka, Giichi Goto, Hasan Parvez, Moussa B H Youdim. A screening system of prodrugs selective for MAO-A or MAO-B.
Neurotoxicology.
2004 Jan; 25(1-2):293-302. doi:
10.1016/s0161-813x(03)00108-6
. [PMID: 14697904] - Mi-Kyung Lee, Eun-Mi Park, Song-Hae Bok, Un Ju Jung, Ji-Young Kim, Yong Bok Park, Tae-Lin Huh, Oh-Shin Kwon, Myung-Sook Choi. Two cinnamate derivatives produce similar alteration in mRNA expression and activity of antioxidant enzymes in rats.
Journal of biochemical and molecular toxicology.
2003; 17(5):255-62. doi:
10.1002/jbt.10087
. [PMID: 14595847] - Adam Wright, William A Bubb, Clare L Hawkins, Michael J Davies. Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues.
Photochemistry and photobiology.
2002 Jul; 76(1):35-46. doi:
10.1562/0031-8655(2002)076<0035:sompoe>2.0.co;2
. [PMID: 12126305] - Héctor M Alvarez, Heinrich Luftmann, Roxana A Silva, Ana C Cesari, Alberto Viale, Marc Wältermann, Alexander Steinbüchel. Identification of phenyldecanoic acid as a constituent of triacylglycerols and wax ester produced by Rhodococcus opacus PD630.
Microbiology (Reading, England).
2002 May; 148(Pt 5):1407-12. doi:
10.1099/00221287-148-5-1407
. [PMID: 11988514] - N G Coldham, C Darby, M Hows, L J King, A Q Zhang, M J Sauer. Comparative metabolism of genistin by human and rat gut microflora: detection and identification of the end-products of metabolism.
Xenobiotica; the fate of foreign compounds in biological systems.
2002 Jan; 32(1):45-62. doi:
10.1080/00498250110085809
. [PMID: 11820509] - R Debowska, A Podstolski. Properties of diphenolase from Vanilla planifolia (Andr.) shoot primordia cultured in vitro.
Journal of agricultural and food chemistry.
2001 Jul; 49(7):3432-7. doi:
10.1021/jf001180z
. [PMID: 11453787] - J Meyer, U Karst. Enzyme-linked immunosorbent assays based on peroxidase labels and enzyme-amplified lanthanide luminescence detection.
The Analyst.
2001 Feb; 126(2):175-8. doi:
10.1039/b008293g
. [PMID: 11235099] - B Schmitt, B Schneider. Phenylpropanoid interconversion in Anigozanthos preissii observed by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy.
Phytochemical analysis : PCA.
2001 Jan; 12(1):43-7. doi:
10.1002/1099-1565(200101/02)12:1<43::aid-pca546>3.0.co;2-z
. [PMID: 11704960] - J D Cremin, J K Drackley, L R Hansen, D E Grum, J Odle, G C Fahey. Effects of glycine and bovine serum albumin on inhibition of propionate metabolism in ovine hepatocytes caused by reduced phenolic monomers.
Journal of animal science.
1995 Oct; 73(10):3009-21. doi:
10.2527/1995.73103009x
. [PMID: 8617672] - I M Roberts, S L Jones, R R Premier, J C Cox. A comparison of the sensitivity and specificity of enzyme immunoassays and time-resolved fluoroimmunoassay.
Journal of immunological methods.
1991 Sep; 143(1):49-56. doi:
10.1016/0022-1759(91)90271-g
. [PMID: 1919036] - R Ekman, L Salford, A Brun, I Larsson. Hydra head activator-like immunoreactivity in human brain astrocytomas grade III-IV and the surrounding brain tissue.
Peptides.
1990 Mar; 11(2):271-5. doi:
10.1016/0196-9781(90)90081-f
. [PMID: 2162530] - T Matsumoto, T Furuta, Y Nimura, O Suzuki. 3-(p-hydroxyphenyl)propionic acid as a new fluorogenic reagent for amine oxidase assays.
Analytical biochemistry.
1984 Apr; 138(1):133-6. doi:
10.1016/0003-2697(84)90780-2
. [PMID: 6428269] - R Ekman, I Larsson, M Malmquist, J I Thorell. Radioimmunoassay of delta sleep-inducing peptide using an iodinated p-hydroxyphenylpropionic acid derivative as tracer.
Regulatory peptides.
1983 Aug; 6(4):371-8. doi:
10.1016/0167-0115(83)90266-5
. [PMID: 6688882] - H Kosuge, M Maeda, A Tsuji. Enzyme immunoassay of cyclazocine using peroxidase as label.
Journal of pharmacobio-dynamics.
1982 Jun; 5(6):373-8. doi:
10.1248/bpb1978.5.373
. [PMID: 6750077] - W M Williams, K C Huang. Structural specificity in the renal tubular transport of tyrosine.
The Journal of pharmacology and experimental therapeutics.
1981 Oct; 219(1):69-74. doi:
. [PMID: 7288617]
- M Fuchs-Mettler, H C Curtius, K Baerlocher, L Ettlinger. A new rearrangement reaction in tyrosine metabolism.
European journal of biochemistry.
1980 Jul; 108(2):527-34. doi:
10.1111/j.1432-1033.1980.tb04749.x
. [PMID: 7408866] - F M Finn, G Titus, J A Montibeller, K Hofmann. Hormone-receptor studies with avidin and biotinylinsulin-avidin complexes.
The Journal of biological chemistry.
1980 Jun; 255(12):5742-6. doi:
10.1016/s0021-9258(19)70692-9
. [PMID: 6991497] - L Pijewska. Isolation of phloretic acid from plant material.
Polish journal of pharmacology and pharmacy.
1973; 25(5):465-7. doi:
"
. [PMID: 4777351]