N1-acetylspermine (BioDeep_00000405422)

Main id: BioDeep_00000001384

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


N1-acetylspermine

化学式: C12H28N4O (244.2262998)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)NCCCNCCCCNCCCN
InChI: InChI=1S/C12H28N4O/c1-12(17)16-11-5-10-15-8-3-2-7-14-9-4-6-13/h14-15H,2-11,13H2,1H3,(H,16,17)

描述信息

同义名列表

2 个代谢物同义名

N1-acetylspermine; N1-Acetylspermine



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Manuela Cervelli, Emanuela Angelucci, Pasquale Stano, Loris Leboffe, Rodolfo Federico, Giovanni Antonini, Paolo Mariottini, Fabio Polticelli. The Glu²¹⁶/Ser²¹⁸ pocket is a major determinant of spermine oxidase substrate specificity. The Biochemical journal. 2014 Aug; 461(3):453-9. doi: 10.1042/bj20140305. [PMID: 24854736]
  • Ran Liu, Ying Jia, Weiming Cheng, Junhong Ling, Lili Liu, Kaishun Bi, Qing Li. Determination of polyamines in human urine by precolumn derivatization with benzoyl chloride and high-performance liquid chromatography coupled with Q-time-of-flight mass spectrometry. Talanta. 2011 Jan; 83(3):751-6. doi: 10.1016/j.talanta.2010.10.039. [PMID: 21147316]
  • Masao Kawakita, Kyoko Hiramatsu, Mari Yanagiya, Yosuke Doi, Mieko Kosaka. Determination of N¹,N¹²-diacetylspermine in urine: a novel tumor marker. Methods in molecular biology (Clifton, N.J.). 2011; 720(?):367-78. doi: 10.1007/978-1-61779-034-8_23. [PMID: 21318886]
  • Toshiaki Miki, Kyoko Hiramatsu, Masao Kawakita. Interaction of N1,N12-diacetylspermine with polyamine transport systems of polarized porcine renal cell line LLC-PK1. Journal of biochemistry. 2005 Oct; 138(4):479-84. doi: 10.1093/jb/mvi141. [PMID: 16272143]
  • Toshio Tanabe, Masashi Shin, Kunio Fujiwara. Immunoelectron microscopy study of polyamines using a newly prepared monoclonal antibody against spermidine: use of a mixture of glutaraldehyde and paraformaldehyde as a cross-linking agent in the preparation of the antigen. Journal of biochemistry. 2004 Apr; 135(4):501-7. doi: 10.1093/jb/mvh066. [PMID: 15115775]
  • Tianyun Wu, Victoria Yankovskaya, William S McIntire. Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase. The Journal of biological chemistry. 2003 Jun; 278(23):20514-25. doi: 10.1074/jbc.m302149200. [PMID: 12660232]
  • K Fujiwara, Y Kaminishi, T Kitagawa, D Tsuru, M Yabuuchi, H Kanetake, K Nomata. Preparation of monoclonal antibodies against N-(gamma-maleimidobutyryloxy)succinimide (GMBS)-conjugated acetylspermine, and development of an enzyme-linked immunosorbent assay (ELISA) for N1,N12-diacetylspermine. Journal of biochemistry. 1998 Jul; 124(1):244-9. doi: 10.1093/oxfordjournals.jbchem.a022088. [PMID: 9644270]
  • K Fujiwara, H Kanetake, K Furukawa, Y Masuyama, G Bai, H Tanimori, T Kitagawa. Determination of urinary acetylpolyamines by a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Journal of biochemistry. 1995 Dec; 118(6):1211-5. doi: 10.1093/oxfordjournals.jbchem.a125009. [PMID: 8720137]
  • D L Bratton. Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost. The Journal of biological chemistry. 1994 Sep; 269(36):22517-23. doi: 10.1016/s0021-9258(17)31677-0. [PMID: 8077200]
  • L C Govaerts, G A van den Berg, A Theeuwes, F A Muskiet, L A Monnens. Urinary polyamine and metabolite excretion by children with Zellweger's syndrome. Clinica chimica acta; international journal of clinical chemistry. 1990 Nov; 192(1):61-7. doi: 10.1016/0009-8981(90)90272-t. [PMID: 2261698]
  • F N Bolkenius, P Bey, N Seiler. Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role. Biochimica et biophysica acta. 1985 Jan; 838(1):69-76. doi: 10.1016/0304-4165(85)90251-x. [PMID: 3967048]
  • W J Hrushesky, J Merdink, M M Abdel-Monem. Circadian rhythmicity of polyamine urinary excretion. Cancer research. 1983 Aug; 43(8):3944-7. doi: NULL. [PMID: 6861156]
  • C E Prussak, D H Russell. Single-step high-performance liquid chromatographic method for the analysis of acetylated polyamines. Journal of chromatography. 1982 Apr; 229(1):47-56. doi: 10.1016/s0378-4347(00)86035-1. [PMID: 7085834]
  • N Seiler, F N Bolkenius, S Sarhan. Formation of acetylpolyamines in the liver of fasting animals. The International journal of biochemistry. 1981; 13(12):1205-14. doi: 10.1016/0020-711x(81)90066-5. [PMID: 6172297]