S-Sulfocysteine (BioDeep_00000400345)
Main id: BioDeep_00000001364
natural product PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C3H7NO5S2 (200.97656519999998)
中文名称: S-磺基-L-半胱氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(=O)O)N)SS(=O)(=O)O
InChI: InChI=1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:27891
- KEGG: C05824
- PubChem: 115015
- DrugBank: DB04370
- ChEMBL: CHEMBL457665
- CAS: 1637-71-4
- MoNA: PT209910
- MoNA: PT109910
- PubChem: 8119
- PDB-CCD: CSU
- 3DMET: B01899
- NIKKAJI: J832.997D
- KNApSAcK: 27891
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yi Jiang, Brandon Mistretta, Sarah H Elsea, Qin Sun. Development of a rapid UPLC-MS/MS determination of urine sulfocysteine for diagnosis of sulfocysteinuria and molybdenum co-factor deficiencies.
Bioanalysis.
2018 May; 10(10):747-756. doi:
10.4155/bio-2017-0278
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The Journal of clinical investigation.
2017 12; 127(12):4365-4378. doi:
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Human genetics.
2016 07; 135(7):813-26. doi:
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. [PMID: 27138983] - H Westerlinck, L Meylaerts, M R Van Hoestenberghe, A Rossi. Sulfite oxidase deficiency in a newborn.
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10.5334/jbr-btr.40
. [PMID: 25073245] - Cecilia Gotor, Luis C Romero. S-sulfocysteine synthase function in sensing chloroplast redox status.
Plant signaling & behavior.
2013 Mar; 8(3):e23313. doi:
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Advances in experimental medicine and biology.
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Phytochemistry.
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Journal of inherited metabolic disease.
2012 Nov; 35(6):1031-6. doi:
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. [PMID: 22403017] - Kenjiro Kikuchi, Shin-ichiro Hamano, Hiroshi Mochizuki, Kimiyoshi Ichida, Hiroyuki Ida. Molybdenum cofactor deficiency mimics cerebral palsy: differentiating factors for diagnosis.
Pediatric neurology.
2012 Aug; 47(2):147-9. doi:
10.1016/j.pediatrneurol.2012.04.013
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Journal of inherited metabolic disease.
2011 Apr; 34(2):529-38. doi:
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. [PMID: 21305354] - Maria Angeles Bermúdez, Maria Angeles Páez-Ochoa, Cecilia Gotor, Luis C Romero. Arabidopsis S-sulfocysteine synthase activity is essential for chloroplast function and long-day light-dependent redox control.
The Plant cell.
2010 Feb; 22(2):403-16. doi:
10.1105/tpc.109.071985
. [PMID: 20179139] - Ingrid Brucknerova, Darina Behulova, Vladimir Bzduch, Mojmir Mach, Michal Dubovicky, Eduard Ujhazy. Newborn with neonatal form of molybdenum cofactor deficiency - the first patient in the Slovak Republic.
Neuro endocrinology letters.
2010; 31 Suppl 2(?):5-7. doi:
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- L H Ngu, B Afroze, B C Chen, O Affandi, M Y Zabedah. Molybdenum cofactor deficiency in a Malaysian child.
Singapore medical journal.
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Drug design, development and therapy.
2009 Sep; 3(?):119-29. doi:
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. [PMID: 19920928] - A Macaya, L Brunso, N Fernández-Castillo, J A Arranz, H B Ginjaar, E Cuenca-León, R Corominas, M Roig, B Cormand. Molybdenum cofactor deficiency presenting as neonatal hyperekplexia: a clinical, biochemical and genetic study.
Neuropediatrics.
2005 Dec; 36(6):389-94. doi:
10.1055/s-2005-872877
. [PMID: 16429380] - Emma E Hobson, Sumesh Thomas, Patricia M Crofton, Alison D Murray, John C S Dean, David Lloyd. Isolated sulphite oxidase deficiency mimics the features of hypoxic ischaemic encephalopathy.
European journal of pediatrics.
2005 Nov; 164(11):655-9. doi:
10.1007/s00431-005-1729-5
. [PMID: 16025295] - Wen-Hann Tan, Florian S Eichler, Sadaf Hoda, Melissa S Lee, Hagit Baris, Catherine A Hanley, P Ellen Grant, Kalpathy S Krishnamoorthy, Vivian E Shih. Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature.
Pediatrics.
2005 Sep; 116(3):757-66. doi:
10.1542/peds.2004-1897
. [PMID: 16140720] - M Z Seidahmed, E A Alyamani, M S Rashed, A A Saadallah, O B Abdelbasit, M M Shaheed, A Rasheed, F A Hamid, M A Sabry. Total truncation of the molybdopterin/dimerization domains of SUOX protein in an Arab family with isolated sulfite oxidase deficiency.
American journal of medical genetics. Part A.
2005 Jul; 136(2):205-9. doi:
10.1002/ajmg.a.30796
. [PMID: 15952210] - Mohamed S Rashed, Amal A A Saadallah, Zuhair Rahbeeni, Wafaa Eyaid, Mohamed Z Seidahmed, Saad Al-Shahwan, Mustafa A M Salih, Mohammad E Osman, Mohamed Al-Amoudi, Lujane Al-Ahaidib, Minnie Jacob. Determination of urinary S-sulphocysteine, xanthine and hypoxanthine by liquid chromatography-electrospray tandem mass spectrometry.
Biomedical chromatography : BMC.
2005 Apr; 19(3):223-30. doi:
10.1002/bmc.439
. [PMID: 15558695] - Toyofumi Nakanishi, Takako Sato, Saburo Sakoda, Masanori Yoshioka, Akira Shimizu. Modification of cysteine residue in transthyretin and a synthetic peptide: analyses by electrospray ionization mass spectrometry.
Biochimica et biophysica acta.
2004 Apr; 1698(1):45-53. doi:
10.1016/j.bbapap.2003.10.005
. [PMID: 15063314] - H F Lee, B S C Mak, C S Chi, C R Tsai, C H Chen, S G Shu. A novel mutation in neonatal isolated sulphite oxidase deficiency.
Neuropediatrics.
2002 Aug; 33(4):174-9. doi:
10.1055/s-2002-34491
. [PMID: 12368985] - M Topcu, T Coskun, G Haliloglu, I Saatci. Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy.
Journal of child neurology.
2001 Apr; 16(4):264-70. doi:
10.1177/088307380101600406
. [PMID: 11332461] - J L Johnson, K V Rajagopalan. An HPLC assay for detection of elevated urinary S-sulphocysteine, a metabolic marker of sulphite oxidase deficiency.
Journal of inherited metabolic disease.
1995; 18(1):40-7. doi:
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Biochemistry and molecular biology international.
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Neuroscience.
1992 Sep; 50(1):107-15. doi:
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European journal of pediatrics.
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Journal of inherited metabolic disease.
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. [PMID: 2501590] - C L Weinstein, O W Griffith. Cysteinesulfonate and beta-sulfopyruvate metabolism. Partitioning between decarboxylation, transamination, and reduction pathways.
The Journal of biological chemistry.
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- C Vianey-Liaud, P Desjacques, J Gaulme, C Dorche, P Vanlieferinghen, P Dechelotte, P Divry. A new case of isolated sulphite oxidase deficiency with rapid fatal outcome.
Journal of inherited metabolic disease.
1988; 11(4):425-6. doi:
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. [PMID: 3149702] - W Moore, H L Wiener, A Meister. Inactivation of gamma-glutamylcysteine synthetase, but not of glutamine synthetase, by S-sulfocysteine and S-sulfohomocysteine.
The Journal of biological chemistry.
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Nutrition reviews.
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. [PMID: 3141849] - D A Keller, D B Menzel. Picomole analysis of glutathione, glutathione disulfide, glutathione S-sulfonate, and cysteine S-sulfonate by high-performance liquid chromatography.
Analytical biochemistry.
1985 Dec; 151(2):418-23. doi:
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Journal of analytical toxicology.
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