nicotinic acid mononucleotide (BioDeep_00000398295)
Main id: BioDeep_00000018643
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C11H14NO9P (335.0406)
中文名称: β-NicotinicAcidMononucleotide
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)O
InChI: InChI=1S/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/m1/s1
描述信息
Acquisition and generation of the data is financially supported in part by CREST/JST.
同义名列表
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Federica Zamporlini, Silverio Ruggieri, Francesca Mazzola, Adolfo Amici, Giuseppe Orsomando, Nadia Raffaelli. Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD(+) biosynthetic machinery in mammalian cells.
The FEBS journal.
2014 Nov; 281(22):5104-19. doi:
10.1111/febs.13050. [PMID: 25223558] - Sathisha Upparahalli Venkateshaiah, Sharmin Khan, Wen Ling, Rakesh Bam, Xin Li, Frits van Rhee, Saad Usmani, Bart Barlogie, Joshua Epstein, Shmuel Yaccoby. NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
Experimental hematology.
2013 Jun; 41(6):547-557.e2. doi:
10.1016/j.exphem.2013.02.008. [PMID: 23435312] - Hyung-Seop Youn, Mun-Kyoung Kim, Gil Bu Kang, Tae Gyun Kim, Jung-Gyu Lee, Jun Yop An, Kyoung Ryoung Park, Youngjin Lee, Jung Youn Kang, Hye-Eun Song, Inju Park, Chunghee Cho, Shin-Ichi Fukuoka, Soo Hyun Eom. Crystal structure of Sus scrofa quinolinate phosphoribosyltransferase in complex with nicotinate mononucleotide.
PloS one.
2013; 8(4):e62027. doi:
10.1371/journal.pone.0062027. [PMID: 23626766] - Hyung-Seop Youn, Mun-Kyoung Kim, Gil Bu Kang, Tae Gyun Kim, Jun Yop An, Jung-Gyu Lee, Kyoung Ryoung Park, Youngjin Lee, Shin-Ichi Fukuoka, Soo Hyun Eom. Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase from porcine kidney in complex with nicotinate mononucleotide.
Acta crystallographica. Section F, Structural biology and crystallization communications.
2012 Dec; 68(Pt 12):1488-90. doi:
10.1107/s1744309112040638. [PMID: 23192029] - Hiroshi Ashihara, Yuling Yin, Riko Katahira, Shin Watanabe, Tetsuro Mimura, Hamako Sasamoto. Comparison of the formation of nicotinic acid conjugates in leaves of different plant species.
Plant physiology and biochemistry : PPB.
2012 Nov; 60(?):190-5. doi:
10.1016/j.plaphy.2012.08.007. [PMID: 22983143] - Shin-nosuke Hashida, Hideyuki Takahashi, Maki Kawai-Yamada, Hirofumi Uchimiya. Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth.
The Plant journal : for cell and molecular biology.
2007 Feb; 49(4):694-703. doi:
10.1111/j.1365-313x.2006.02989.x. [PMID: 17270012] - Keri Wang, Kenneth Conn, George Lazarovits. Involvement of quinolinate phosphoribosyl transferase in promotion of potato growth by a Burkholderia strain.
Applied and environmental microbiology.
2006 Jan; 72(1):760-8. doi:
10.1128/aem.72.1.760-768.2006. [PMID: 16391116] - Graham Noctor, Guillaume Queval, Bertrand Gakière. NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.
Journal of experimental botany.
2006; 57(8):1603-20. doi:
10.1093/jxb/erj202. [PMID: 16714307] - K Shibata, T Fukuwatari, E Sugimoto. Reversed-phase high-performance liquid chromatography of nicotinic acid mononucleotide for measurement of quinolinate phosphoribosyltransferase.
Journal of chromatography. B, Biomedical sciences and applications.
2000 Dec; 749(2):281-5. doi:
10.1016/s0378-4347(00)00406-0. [PMID: 11145065] - A C Foster, E Okuno, D S Brougher, R Schwarcz. A radioenzymatic assay for quinolinic acid.
Analytical biochemistry.
1986 Oct; 158(1):98-103. doi:
10.1016/0003-2697(86)90595-6. [PMID: 2948416] - A C Foster, R Schwarcz. Characterization of quinolinic acid phosphoribosyltransferase in human blood and observations in Huntington's disease.
Journal of neurochemistry.
1985 Jul; 45(1):199-205. doi:
10.1111/j.1471-4159.1985.tb05493.x. [PMID: 2582090]
