AI3-36426 (BioDeep_00000397367)

 

Secondary id: BioDeep_00000180863, BioDeep_00000268005

PANOMIX_OTCML-2023


代谢物信息卡片


Methyl 3,5-dimethoxy-4-hydroxybenzoate; Methyl syringate

化学式: C10H12O5 (212.06847019999998)
中文名称: 3,5-二甲氧基-4-羟基苯甲酸甲酯, 丁香酸甲酯
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 1.47%

分子结构信息

SMILES: COC1=CC(=CC(=C1O)OC)C(=O)OC
InChI: InChI=1S/C10H12O5/c1-13-7-4-6(10(12)15-3)5-8(14-2)9(7)11/h4-5,11H,1-3H3

描述信息

Methyl syringate is a benzoate ester obtained by the formal condensation of carboxy group of syringic acid with methanol. It has a role as a plant metabolite. It is a benzoate ester, a dimethoxybenzene and a member of phenols. It is functionally related to a syringic acid.
Methyl 4-hydroxy-3,5-dimethoxybenzoate is a natural product found in Buxus natalensis, Cestrum parqui, and other organisms with data available.
A benzoate ester obtained by the formal condensation of carboxy group of syringic acid with methanol.
Methyl syringate, a chemical marker of asphodel monofloral honey, is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a TRPA1 agonist[1][2][3].
Methyl syringate, a chemical marker of asphodel monofloral honey, is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a TRPA1 agonist[1][2][3].

同义名列表

14 个代谢物同义名

Methyl 3,5-dimethoxy-4-hydroxybenzoate; Methyl syringate; Benzoic acid, 4-hydroxy-3,5-dimethoxy-, methyl ester; 4-Hydroxy-3,5-dimethoxybenzoic Acid Methyl Ester; methyl (4-hydroxy-3,5-dimethoxy)benzoate; methyl 4-hydroxy-3,5-dimethoxy-benzoate; methyl 3,5-dimethoxy-4-hydroxy-benzoate; Methyl 3,5-dimethoxy-4-hydroxybenzoate; Methyl 4-hydroxy-3,5-dimethoxybenzoate; Syringic acid monomethyl ester; Syringic acid methyl ester; Methyl syringate; UNII-W5A196MP8A; W5A196MP8A; AI3-36426



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Youssef Elamine, Badiaa Lyoussi, Maria G Miguel, Ofélia Anjos, Letícia Estevinho, Manuel Alaiz, Julio Girón-Calle, Jesús Martín, Javier Vioque. Physicochemical characteristics and antiproliferative and antioxidant activities of Moroccan Zantaz honey rich in methyl syringate. Food chemistry. 2021 Mar; 339(?):128098. doi: 10.1016/j.foodchem.2020.128098. [PMID: 33152883]
  • Yoji Kato, Masaki Kawai, Shota Kawai, Yayako Okano, Natsumi Rokkaku, Akari Ishisaka, Kaeko Murota, Toshiyuki Nakamura, Yoshimasa Nakamura, Shinichi Ikushiro. Dynamics of the Cellular Metabolism of Leptosperin Found in Manuka Honey. Journal of agricultural and food chemistry. 2019 Oct; 67(39):10853-10862. doi: 10.1021/acs.jafc.9b03894. [PMID: 31496237]
  • Akari Ishisaka, Shinichi Ikushiro, Mie Takeuchi, Yukako Araki, Maki Juri, Yui Yoshiki, Yoshichika Kawai, Toshio Niwa, Noritoshi Kitamoto, Toshiyuki Sakaki, Hirohito Ishikawa, Yoji Kato. In vivo absorption and metabolism of leptosperin and methyl syringate, abundantly present in manuka honey. Molecular nutrition & food research. 2017 09; 61(9):. doi: 10.1002/mnfr.201700122. [PMID: 28444960]
  • Yoji Kato, Rie Fujinaka, Maki Juri, Yui Yoshiki, Akari Ishisaka, Noritoshi Kitamoto, Yoko Nitta, Hirohito Ishikawa. Characterization of a Monoclonal Antibody against Syringate Derivatives: Application of Immunochemical Detection of Methyl Syringate in Honey. Journal of agricultural and food chemistry. 2016 Aug; 64(33):6495-501. doi: 10.1021/acs.jafc.6b01328. [PMID: 27477590]
  • Shohei Sakuda, Tomoya Yoshinari, Tomohiro Furukawa, Usuma Jermnak, Keiko Takagi, Kurin Iimura, Toshiyoshi Yamamoto, Michio Suzuki, Hiromichi Nagasawa. Search for aflatoxin and trichothecene production inhibitors and analysis of their modes of action. Bioscience, biotechnology, and biochemistry. 2016; 80(1):43-54. doi: 10.1080/09168451.2015.1086261. [PMID: 26376763]
  • Min Jung Kim, Hee Jin Son, Seo Hyeon Song, Myungji Jung, Yiseul Kim, Mee-Ra Rhyu. The TRPA1 agonist, methyl syringate suppresses food intake and gastric emptying. PloS one. 2013; 8(8):e71603. doi: 10.1371/journal.pone.0071603. [PMID: 23990963]
  • Christy E Manyi-Loh, Roland N Ndip, Anna M Clarke. Volatile compounds in honey: a review on their involvement in aroma, botanical origin determination and potential biomedical activities. International journal of molecular sciences. 2011; 12(12):9514-32. doi: 10.3390/ijms12129514. [PMID: 22272147]
  • Igor Jerković, Gordana Hegić, Zvonimir Marijanović, Dragan Bubalo. Organic extractives from Mentha spp. honey and the bee-stomach: methyl syringate, vomifoliol, terpenediol I, hotrienol and other compounds. Molecules (Basel, Switzerland). 2010 Apr; 15(4):2911-24. doi: 10.3390/molecules15042911. [PMID: 20428087]
  • Saulo L Da Silva, Jamal da S Chaar, Tomomasa Yano. Chemotherapeutic potential of two gallic acid derivative compounds from leaves of Casearia sylvestris Sw (Flacourtiaceae). European journal of pharmacology. 2009 Apr; 608(1-3):76-83. doi: 10.1016/j.ejphar.2009.02.004. [PMID: 19222998]
  • Yao-Lan Li, Miao-Xian Su, Ying-Zhou Cen, Xiao-Qi Zhang, Yi Dai, Wen-Cai Ye. [Study on the chemical constituents of Ardisia chinensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2006 Apr; 29(4):331-3. doi: ". [PMID: 16913485]
  • Nicolas Tarbouriech, José A M Prates, Carlos M G A Fontes, Gideon J Davies. Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum. Acta crystallographica. Section D, Biological crystallography. 2005 Feb; 61(Pt 2):194-7. doi: 10.1107/s0907444904029695. [PMID: 15681871]