(S)-2-Propylpiperidine (BioDeep_00000395546)

human metabolite PANOMIX_OTCML-2023 Endogenous PANOMIX_OTCML-2025


Metabolite Card


Cicutin; Cicutine; Conicine;(S)-2-Propylpiperidine;(S)-beta-Propylpiperidine

  Formula: C8H17N (127.1361)
Chinese Names: 2-丙基哌啶, (S) -2-丙基哌啶
  Spectrum Hits: Top Source Viridiplantae(plant) 7.89%

Molecular Structure

SMILES: CCCC1CCCCN1
InChI: InChI=1S/C8H17N/c1-2-5-8-6-3-4-7-9-8/h8-9H,2-7H2,1H3

Description

Coniine is a natural product found in Conium, Sarracenia flava, and other organisms with data available.
(S)-2-Propylpiperidine is found in black elderberry. (S)-2-Propylpiperidine is an alkaloid of Amorphophalus rivieri (devils tongue). (S)-2-Propylpiperidine belongs to the family of Alkaloids and Derivatives. These are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus.
(S)-2-Propylpiperidine is found in black elderberry. (S)-2-Propylpiperidine is an alkaloid of Amorphophalus rivieri (devils tongue
Alkaloid of Amorphophalus rivieri (devils tongue). (S)-2-Propylpiperidine is found in pomegranate and black elderberry.

Synonyms

67 synonym names

Cicutin; Cicutine; Conicine;(S)-2-Propylpiperidine;(S)-beta-Propylpiperidine; 2-N-PropylpiperidinE;DL-Coniine;(2R)-2-Propylpiperidine; ( inverted exclamation markA)-Coniine; coniine hydrochloride, (+-)-isomer; coniine hydrochloride, (S)-isomer; coniine hydrobromide, (S)-isomer; (+/-)-Coniine, >=98\\%, liquid; PIPERIDINE, 2-PROPYL-, (+/-)-; Piperidine, 2-propyl-, (2S)-; Piperidine, 2-propyl-, (+-)-; Piperidine, 2-propyl-, (S)-; (S)-beta-Propylpiperidine; (2S)-2-Propylpiperidine; (R)-2-Propylpiperidine; (1)-2-Propylpiperidine; (S)-2-Propylpiperidine; coniine, (+-)-isomer; 2-N-propylpiperidine; 2-Propyl-piperidine; coniine, (S)-isomer; 2-Propylpiperidine; UNII-04R53ZF48T; CONIINE, (+/-)-; (S)-(+)-ConIIne; Tox21_112688_1; (+/-)-Coniine; Tox21_112688; (+-)-Coniine; CONIINE, DL-; alpha-Conine; (S)-Coniine; (±)-Coniine; (+)-Coniine; d-Conicine; dl-Coniine; 04R53ZF48T; CONIINUM; cicutine; conicine; Cicutin; Conicin; Coniine; Conine; koniin; Coniin; Coniine; (S)-2-Propylpiperidine; Coniine; (+)Coniine; (S)(+)Coniine; (S)2Propylpiperidine; (S)betaPropylpiperidine; (S)Coniine; 5-20-04-00205 (Beilstein Handbook Reference); CONIINE [HSDB]; CONIINE [MI]; CONIINE, D/L-(RG); CONIINUM [HPUS]; D-2-(n-Propyl)piperidine; d-Coniine; dConicine; NDNUANOUGZGEPO-QMMMGPOBSA-N; Piperidine, 2propyl, (S); (+/-)-Coniine, >=98%, liquid; 1ST158026; piperidine, 2-n-propyl-; piperidine, 2-propyl-



Cross Reference

26 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



Literature Reference

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  • Carlo Basile. [Rhabdomyolysis: have you considered food poisoning from quails?]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 2020 Apr; 37(2):. doi: . [PMID: 32281758]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • M V Karakasi, S Tologkos, V Papadatou, N Raikos, M Lambropoulou, P Pavlidis. Conium maculatum intoxication: Literature review and case report on hemlock poisoning. Forensic science review. 2019 Jan; 31(1):23-36. doi: ". [PMID: 30594904]
  • Hannu Hotti, Heiko Rischer. The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom. Molecules (Basel, Switzerland). 2017 Nov; 22(11):. doi: 10.3390/molecules22111962. [PMID: 29135964]
  • Hannu Hotti, Peddinti Gopalacharyulu, Tuulikki Seppänen-Laakso, Heiko Rischer. Metabolite profiling of the carnivorous pitcher plants Darlingtonia and Sarracenia. PloS one. 2017; 12(2):e0171078. doi: 10.1371/journal.pone.0171078. [PMID: 28222171]
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  • Benedict T Green, Stephen T Lee, Kevin D Welch, James A Pfister, Kip E Panter. Fetal muscle-type nicotinic acetylcholine receptor activation in TE-671 cells and inhibition of fetal movement in a day 40 pregnant goat model by optical isomers of the piperidine alkaloid coniine. The Journal of pharmacology and experimental therapeutics. 2013 Jan; 344(1):295-307. doi: 10.1124/jpet.112.199588. [PMID: 23086230]
  • Okan Arihan, Mustafa Boz, Alper B Iskit, Mustafa Ilhan. Antinociceptive activity of coniine in mice. Journal of ethnopharmacology. 2009 Sep; 125(2):274-8. doi: 10.1016/j.jep.2009.06.032. [PMID: 19580858]
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  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • K Suvardhan, K Suresh Kumar, L Krishnaiah, S Prabakhara Rao, P Chiranjeevi. The determination of nickel(II) after on-line sorbent preconcentration by inductively coupled plasma atomic emission spectrometry using Borassus Flabellifer inflorescence loaded with coniine dithiocarbamate. Journal of hazardous materials. 2004 Aug; 112(3):233-8. doi: 10.1016/j.jhazmat.2004.05.003. [PMID: 15302444]
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