isofuranodiene (BioDeep_00000295547)
Main id: BioDeep_00000000693
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C15H20O (216.1514)
中文名称: 异莪术呋喃二烯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CCC2=C(CC(=CCC1)C)OC=C2C
InChI: InChI=1S/C15H20O/c1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/h6-7,10H,4-5,8-9H2,1-3H3/b11-7+,12-6-
描述信息
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- PubChem: 9601230
- CAS: 57566-47-9
- CAS: 19912-61-9
- PMhub: MS000054731
- KEGG: C16959
- PubChem: 96023446
- KNApSAcK: 80824
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Akhila Nair, Augustine Amalraj, Joby Jacob, Ajaikumar B Kunnumakkara, Sreeraj Gopi. Non-Curcuminoids from Turmeric and Their Potential in Cancer Therapy and Anticancer Drug Delivery Formulations.
Biomolecules.
2019 01; 9(1):. doi:
10.3390/biom9010013
. [PMID: 30609771] - Qi Kong, Yong Ma, Jie Yu, Xiuping Chen. Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach.
Scientific reports.
2017 Nov; 7(1):15543. doi:
10.1038/s41598-017-15812-9
. [PMID: 29138518] - Jianmei Zhang, Yunpeng He, Jianqi Jiang, Meng Li, Chenhao Jin, Lin Wang, Dongkai Wang. In vitro and in vivo evaluation of folate-mediated PEGylated nanostructured lipid carriers for the efficient delivery of furanodiene.
Drug development and industrial pharmacy.
2017 Oct; 43(10):1610-1618. doi:
10.1080/03639045.2017.1328429
. [PMID: 28481661] - Zhang-Feng Zhong, Wen Tan, Ke Tian, Hua Yu, Wen-An Qiang, Yi-Tao Wang. Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro.
Oncology reports.
2017 Apr; 37(4):2016-2024. doi:
10.3892/or.2017.5435
. [PMID: 28184941] - Zhang-Feng Zhong, Wen Tan, William W Qiang, Virginia L Scofield, Ke Tian, Chun-Ming Wang, Wen-An Qiang, Yi-Tao Wang. Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner.
Molecular bioSystems.
2016 04; 12(5):1626-37. doi:
10.1039/c6mb00003g
. [PMID: 26987443] - Baolian Wang, Shuang Yang, Li Sheng, Yan Li. Simultaneous quantification of curdione, furanodiene and germacrone in rabbit plasma using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.
Biomedical chromatography : BMC.
2015 Sep; 29(9):1393-8. doi:
10.1002/bmc.3436
. [PMID: 25678109] - Li-Feng Zhang, Tao-Tao Lu, Shu-Qiu Zhang, Wen-Han Lin, Qing-Shan Li. Pharmacokinetics and tissue distribution of furanodiene W/O/W multiple emulsions in rats by a fast and sensitive HPLC-APCI-MS/MS method.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 Dec; 43(12):1095-102. doi:
10.3109/00498254.2013.793434
. [PMID: 23638824] - Meng Chen, Yan Lou, Yaodong Wu, Zhaoke Meng, Liping Li, Lushan Yu, Su Zeng, Hui Zhou, Huidi Jiang. Characterization of in vivo and in vitro metabolites of furanodiene in rats by high performance liquid chromatography-electrospray ionization mass spectrometry and nuclear magnetic resonance spectra.
Journal of pharmaceutical and biomedical analysis.
2013 Dec; 86(?):161-8. doi:
10.1016/j.jpba.2013.08.008
. [PMID: 23998967] - Ilaria Bellezza, Annalisa Mierla, Silvia Grottelli, Maria Carla Marcotullio, Federica Messina, Luca Roscini, Gianluigi Cardinali, Massimo Curini, Alba Minelli. Furanodien-6-one from Commiphora erythraea inhibits the NF-κB signalling and attenuates LPS-induced neuroinflammation.
Molecular immunology.
2013 Jul; 54(3-4):347-54. doi:
10.1016/j.molimm.2013.01.003
. [PMID: 23357788] - Luana Quassinti, Massimo Bramucci, Giulio Lupidi, Luciano Barboni, Massimo Ricciutelli, Gianni Sagratini, Fabrizio Papa, Giovanni Caprioli, Dezemona Petrelli, Luca A Vitali, Sauro Vittori, Filippo Maggi. In vitro biological activity of essential oils and isolated furanosesquiterpenes from the neglected vegetable Smyrnium olusatrum L. (Apiaceae).
Food chemistry.
2013 Jun; 138(2-3):808-13. doi:
10.1016/j.foodchem.2012.11.075
. [PMID: 23411181] - Feng-Qing Yang, Jing Yang, Xue-Mei Zhang, Pan Xu, Zhi-Ning Xia. Analysis of volatile components in Curcuma rhizome by microemulsion electrokinetic chromatography.
Journal of chromatographic science.
2013 Feb; 51(2):155-60. doi:
10.1093/chromsci/bms120
. [PMID: 22824329] - Lixia Pei, Sheng Liu, Jin Zheng, Xiuping Chen. A sensitive method for determination of furanodiene in rat plasma using liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
Biomedical chromatography : BMC.
2012 Jul; 26(7):826-32. doi:
10.1002/bmc.1736
. [PMID: 22052715] - Zhang-Feng Zhong, Pui-Man Hoi, Guo-Sheng Wu, Zeng-Tao Xu, Wen Tan, Xiu-Ping Chen, Liao Cui, Tie Wu, Yi-Tao Wang. Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo.
Journal of ethnopharmacology.
2012 Jun; 141(2):721-7. doi:
10.1016/j.jep.2011.08.052
. [PMID: 21911050] - Yang Qu, Fengming Xu, Seikou Nakamura, Hisashi Matsuda, Yutana Pongpiriyadacha, Lijun Wu, Masayuki Yoshikawa. Sesquiterpenes from Curcuma comosa.
Journal of natural medicines.
2009 Jan; 63(1):102-4. doi:
10.1007/s11418-008-0282-8
. [PMID: 18663560] - Yu Xiao, Feng-Qing Yang, Shao-Ping Li, Jian-Li Gao, Guang Hu, Sin-Cheng Lao, Emilia Leong Conceição, Kwok-Pui Fung, Yi-Tao Wangl, Simon Ming-Yuen Lee. Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells.
Cancer biology & therapy.
2007 Jul; 6(7):1044-50. doi:
10.4161/cbt.6.7.4317
. [PMID: 17611410]