Rupestonic acid (BioDeep_00000277046)
Main id: BioDeep_00000231483
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C15H20O3 (248.14123700000002)
中文名称: 一枝蒿酮酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=C(C(=O)O)C1CCC(C)C2CC(=O)C(C)=C2C1
InChI: InChI=1S/C15H20O3/c1-8-4-5-11(9(2)15(17)18)6-13-10(3)14(16)7-12(8)13/h8,11-12H,2,4-7H2,1,3H3,(H,17,18)/t8-,11+,12-/m0/s1
描述信息
Rupestonic acid, a sesquiterpene, can inhibit influenza virus[1].
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:183941
- PubChem: 24094149
- PubChem: 3081082
- PubChem: 71761007
- ChEMBL: CHEMBL1956398
- MeSH: rupestonic acid
- ChemIDplus: 0115473637
- CAS: 83161-56-2
- CAS: 115473-63-7
- medchemexpress: HY-N3016
- PMhub: MS000011930
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gen Li, Mamateli Obul, Jiang-Yu Zhao, Ge-Yu Liu, Wei Lu, Haji Akber Aisa. Novel amides modified rupestonic acid derivatives as anti-influenza virus reagents.
Bioorganic & medicinal chemistry letters.
2019 10; 29(19):126605. doi:
10.1016/j.bmcl.2019.08.009. [PMID: 31439378] - Mamateli Obul, Xincheng Wang, Jiangyu Zhao, Gen Li, Haji Akber Aisa, Guozheng Huang. Structural modification on rupestonic acid leads to highly potent inhibitors against influenza virus.
Molecular diversity.
2019 Feb; 23(1):1-9. doi:
10.1007/s11030-018-9840-5. [PMID: 29971616] - Gen Li, Jiang-Yu Zhao, Chao Niu, Li-Fei Nie, Chang-Zhi Dong, Haji Akber Aisa. Structure-activity relationship studies of 1-(1'-hydroxyalkyl)rupestonic acid methyl esters against influenza viruses.
Bioorganic & medicinal chemistry letters.
2017 03; 27(6):1484-1487. doi:
10.1016/j.bmcl.2016.06.011. [PMID: 28196702] - Dongyu Gu, Yi Yang, Qibin Chen, Madina Habasi, Jiangyu Zhao, Haji Akber Aisa. Identification of metabolites of rupestonic acid in rat urine by liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
Biomedical chromatography : BMC.
2015 Apr; 29(4):595-603. doi:
10.1002/bmc.3319. [PMID: 25187340] - Yao-Wu He, Chang-Zhi Dong, Jiang-Yu Zhao, Lin-Lin Ma, Yu-Huan Li, Haji Akber Aisa. 1,2,3-Triazole-containing derivatives of rupestonic acid: click-chemical synthesis and antiviral activities against influenza viruses.
European journal of medicinal chemistry.
2014 Apr; 76(?):245-55. doi:
10.1016/j.ejmech.2014.02.029. [PMID: 24583605] - Zhengyi Gu, Jinhua He, Xi Yang, Xianyi Sha. Quantitative determination of rupestonic acid in rat plasma by high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.
Biomedical chromatography : BMC.
2013 May; 27(5):563-7. doi:
10.1002/bmc.2828. [PMID: 23037995] - Jianping Yong, Canzhong Lu, Haji Akber Aisa. Advances in studies on the rupestonic acid derivatives as anti-influenza agents.
Mini reviews in medicinal chemistry.
2013 Feb; 13(2):310-5. doi:
". [PMID: 22625417] - Yi Yang, Dongyu Gu, Abulimiti Yili, Yongxin Zhao, Dajun He, Haji Akber Aisa. One-step separation and purification of rupestonic acid and chrysosptertin B from Artemisia rupestris L. by high-speed counter-current chromatography.
Phytochemical analysis : PCA.
2010 Mar; 21(2):205-9. doi:
10.1002/pca.1169. [PMID: 19821258] - Yanming Ma, Haji Akber Aisha, Lixin Liao, Sirafil Aibai, Tianyou Zhang, Yoichiro Ito. Preparative isolation and purification of rupestonic acid from the Chinese medicinal plant Artemisia rupestris L. by high-speed counter-current chromatography.
Journal of chromatography. A.
2005 May; 1076(1-2):198-201. doi:
10.1016/j.chroma.2005.04.040. [PMID: 15974089]