Cyclomulberrin (BioDeep_00000270068)

Main id: BioDeep_00000025073

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3,8,10-Trihydroxy-11- (3-methyl-2-butenyl) -6- (2-methyl-1-propenyl) -6H,7H- [ 1 ] benzopyrano [ 4,3-b ] [ 1 ] benzopyran-7-one

化学式: C25H24O6 (420.1572804)
中文名称: 环桑素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C)(C)=CC(O4)C(=C1c(c43)ccc(O)c3)C(c(c2O)c(c(c(O)c2)CC=C(C)C)O1)=O
InChI: InChI=1S/C25H24O6/c1-12(2)5-7-15-17(27)11-18(28)21-23(29)22-20(9-13(3)4)30-19-10-14(26)6-8-16(19)25(22)31-24(15)21/h5-6,8-11,20,26-28H,7H2,1-4H3

描述信息

A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at positions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line.

同义名列表

2 个代谢物同义名

Cyclomulberrin; 3,8,10-Trihydroxy-11- (3-methyl-2-butenyl) -6- (2-methyl-1-propenyl) -6H,7H- [ 1 ] benzopyrano [ 4,3-b ] [ 1 ] benzopyran-7-one



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yan-Qiong Guo, Gui-Hua Tang, Lan-Lan Lou, Wei Li, Bei Zhang, Bo Liu, Sheng Yin. Prenylated flavonoids as potent phosphodiesterase-4 inhibitors from Morus alba: Isolation, modification, and structure-activity relationship study. European journal of medicinal chemistry. 2018 Jan; 144(?):758-766. doi: 10.1016/j.ejmech.2017.12.057. [PMID: 29291443]
  • Hak Ju Lee, Da Hyun Lyu, Uk Koo, Kung-Woo Nam, Seong Su Hong, Kem Ok Kim, Kyeong Ho Kim, Dongho Lee, Woongchon Mar. Protection of prenylated flavonoids from Mori Cortex Radicis (Moraceae) against nitric oxide-induced cell death in neuroblastoma SH-SY5Y cells. Archives of pharmacal research. 2012 Jan; 35(1):163-70. doi: 10.1007/s12272-012-0118-7. [PMID: 22297755]
  • Chang'an Geng, Shuying Yao, Duoqing Xue, Aixue Zuo, Xuemei Zhang, Zhiyong Jiang, Yunbao Ma, Jijun Chen. New isoprenylated flavonoid from Morus alba. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Jun; 35(12):1560-5. doi: . [PMID: 20815207]
  • Yan-Lan Xu, Xu-E Li, Yu-Xiao Zou, Ji-Jun Chen. [Studies on chemical constituents from twigs of Morus atropurpurea]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Nov; 33(21):2499-502. doi: . [PMID: 19149258]