Cleistanthin A (BioDeep_00000259003)

Main id: BioDeep_00000008149

 

PANOMIX_OTCML-2023


代谢物信息卡片


Cleistanthin A

化学式: C28H28O11 (540.1631538)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COc1cc2c(-c3ccc4c(c3)OCO4)c3c(cc2c(OC2OCC(OC)C(OC)C2O)c1OC)COC3=O
InChI: InChI=1S/C28H28O11/c1-31-18-8-14-15(9-19(18)32-2)25(39-28-24(29)26(34-4)21(33-3)11-36-28)16-10-35-27(30)23(16)22(14)13-5-6-17-20(7-13)38-12-37-17/h5-9,21,24,26,28-29H,10-12H2,1-4H3/t21-,24-,26+,28+/m1/s1

描述信息

A member of the class of cleistanthins that is the 4-O-3,4-di-O-methyl-beta-D-xylopyranoside of 1,3-dihydronaphtho[2,3-c]furan-4-ol which is substituted by an oxo group at position 1, methoxy groups at positions 6 and 7, and a 1,3-benzodioxol-5-yl group at position 9. It is one of the toxic principles in Cleistanthus collinus.

同义名列表

1 个代谢物同义名

Cleistanthin A



数据库引用编号

6 个数据库交叉引用编号

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相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Kawin Padmaja, Roshni Parameswaran, G Srisangeetha, Shikha Mary Zachariah, Neetu Prince, Soosai Manickam Amirtham, Uwe Beifuss, Juergen Conrad, Sathya Subramani. Cleistanthin A causes peripheral vasoconstriction and myocardial depression in isolated tissue preparations. Toxicology mechanisms and methods. 2023 Jul; ?(?):1-13. doi: 10.1080/15376516.2023.2237581. [PMID: 37461393]
  • Siddhartha Das, Abdoul Hamide, Manoj K Mohanty, Ravichandran Muthusamy. Fatal Cleistanthus collinus toxicity: a case report and review of literature. Journal of forensic sciences. 2014 Sep; 59(5):1441-7. doi: 10.1111/1556-4029.12519. [PMID: 25040437]
  • Lakana Himakoun, Patoomratana Tuchinda, Pranom Puchadapirom, Ratigon Tammasakchai, Vijittra Leardkamolkarn. Evaluation of genotoxic and anti-mutagenic properties of cleistanthin A and cleistanthoside A tetraacetate. Asian Pacific journal of cancer prevention : APJCP. 2011; 12(12):3271-5. doi: . [PMID: 22471465]
  • S P E Benjamin, M Edwin Fernando, J Jerene Jayanth, B Preetha. Cleistanthus collinus poisoning. The Journal of the Association of Physicians of India. 2006 Sep; 54(?):742-4. doi: . [PMID: 17212028]
  • Patoomratana Tuchinda, Anawat Kumkao, Manat Pohmakotr, Samaisukh Sophasan, Thawatchai Santisuk, Vichai Reutrakul. Cytotoxic arylnaphthalide lignan glycosides from the aerial parts of Phyllanthus taxodiifolius. Planta medica. 2006 Jan; 72(1):60-2. doi: 10.1055/s-2005-873141. [PMID: 16450297]
  • Vinu M Jose, K N Anand, L Jeyaseelan, Kalpana Ernest, Alice Kuruvilla. Effect of potassium channel modulators on toxicity of Cleistanthus collinus. Indian journal of experimental biology. 2004 Jan; 42(1):81-5. doi: NULL. [PMID: 15274486]
  • D K S Subrahmanyam, T Mooney, R Raveendran, B Zachariah. A clinical and laboratory profile of Cleistanthus collinus poisoning. The Journal of the Association of Physicians of India. 2003 Nov; 51(?):1052-4. doi: ". [PMID: 15260387]
  • Shashiraj Eswarappa, Amiya Ranjan Chakraborty, Babu Urumese Palatty, Mabel Vasnaik. Cleistanthus collinus poisoning: case reports and review of the literature. Journal of toxicology. Clinical toxicology. 2003; 41(4):369-72. doi: 10.1081/clt-120022005. [PMID: 12870879]
  • C P Pradheepkumar, G Shanmugam. Anticancer potential of cleistanthin A isolated from the tropical plant Cleistanthus collinus. Oncology research. 1999; 11(5):225-32. doi: . [PMID: 10608617]
  • G Ragupathi, P Prabhasankar, P C Sekharan, K S Annapoorani, C Damodaran. Novel solid-state fluorodensitometric method for the determination of haptens in protein-hapten conjugates. Demonstration with a toxic glycoside of Cleistanthus collinus. Journal of chromatography. 1992 Feb; 574(2):267-71. doi: 10.1016/0378-4347(92)80039-s. [PMID: 1618959]
  • G Ragupathi, P Prabhasankar, P C Sekharan, K S Annapoorani, C Damodaran. Enzyme-linked immunosorbent assay for the phytotoxin cleistanthin A. Journal of immunoassay. 1992; 13(3):321-38. doi: 10.1080/15321819208021236. [PMID: 1506455]
  • K S Annapoorani, P Periakali, S Ilangovan, C Damodaran, P C Sekharan. Spectrofluorometric determination of the toxic constituents of Cleistanthus collinus. Journal of analytical toxicology. 1984 Jul; 8(4):182-6. doi: 10.1093/jat/8.4.182. [PMID: 6471818]