NotoginsenosideFc (BioDeep_00000230762)
Main id: BioDeep_00000018802
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C58H98O26 (1210.6346008)
中文名称: 三七皂苷 FC, 三七皂苷Fc
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)OC7C(C(C(CO7)O)O)O)C)C)O)C)OC8C(C(C(C(O8)COC9C(C(C(CO9)O)O)O)O)O)O)C
InChI: InChI=1S/C58H98O26/c1-24(2)10-9-14-58(8,84-51-46(74)41(69)40(68)31(80-51)23-77-49-44(72)36(64)27(62)21-75-49)25-11-16-57(7)35(25)26(61)18-33-55(5)15-13-34(54(3,4)32(55)12-17-56(33,57)6)81-52-47(42(70)38(66)29(19-59)78-52)83-53-48(43(71)39(67)30(20-60)79-53)82-50-45(73)37(65)28(63)22-76-50/h10,25-53,59-74H,9,11-23H2,1-8H3/t25-,26+,27+,28+,29+,30+,31+,32-,33+,34-,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45+,46+,47+,48+,49-,50-,51-,52-,53-,55-,56+,57+,58-/m0/s1
描述信息
Notoginsenoside Fc is a natural product found in Panax notoginseng and Panax japonicus with data available.
Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy[1].
Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy[1].
同义名列表
3 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhenghong Guo, Zhonghua Luo, Shao Wu, Chunhong Yang, Ting Xiao, Yuqing Zhao. Optimization of Extraction and Separation Process of Notoginsenoside Fc from Panax notoginseng Leaves.
Molecules (Basel, Switzerland).
2023 May; 28(9):. doi:
10.3390/molecules28093915. [PMID: 37175326] - Rufeng Wang, Zhongji Pu, Jonathan Joel Janke, Yu-Cong Zheng, Xu-Dong Kong, Tengfei Niu, Shujuan Zhao, Li Yang, Zhengtao Wang, Jian-He Xu. Engineered Glycosidase for Significantly Improved Production of Naturally Rare Vina-Ginsenoside R7.
Journal of agricultural and food chemistry.
2023 Mar; 71(8):3852-3861. doi:
10.1021/acs.jafc.2c09115. [PMID: 36790033] - Zhengcai Ju, Jia Li, Qian Lu, Yingbo Yang, Li Yang, Zhengtao Wang. Identification and quantitative investigation of the effects of intestinal microflora on the metabolism and pharmacokinetics of notoginsenoside Fc assayed by liquid chromatography with electrospray ionization tandem mass spectrometry.
Journal of separation science.
2019 May; 42(9):1740-1749. doi:
10.1002/jssc.201801237. [PMID: 30805999] - Chao Ma, Huida Guan, Zhengcai Ju, Shuping Li, Gang Deng, Yunpeng Zhang, Qiyan Lin, Xuemei Cheng, Li Yang, Zhengtao Wang, Changhong Wang. Identification and characterization of forced degradation products and stability-indicating assay for notoginsenosidefc by using UHPLC-Q-TOF-MS and UHPLC-MS/MS: Insights into stability profile and degradation pathways.
Journal of separation science.
2019 Apr; 42(8):1550-1563. doi:
10.1002/jssc.201801295. [PMID: 30768757] - Chunyong He, Jia Li, Niusheng Xu, Rufeng Wang, Zeyun Li, Li Yang, Zhengtao Wang. Pharmacokinetics, bioavailability, and metabolism of Notoginsenoside Fc in rats by liquid chromatography/electrospray ionization tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2015 May; 109(?):150-7. doi:
10.1016/j.jpba.2015.02.038. [PMID: 25770412] - J Wei, Y Chen, S Cao. [Saponins in the fruit pedicels of Panax notoginseng (Burk.) F.H. Chen (continue)].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
1992 Oct; 17(10):611-3, 639. doi:
". [PMID: 1294178]