7-Aminobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (BioDeep_00000183373)
human metabolite blood metabolite
代谢物信息卡片
化学式: C7H6N2O3S (198.0099)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 86.47%
分子结构信息
SMILES: C1=CC2=C(C(=C1)N)S(=O)(=O)NC2=O
InChI: InChI=1S/C7H6N2O3S/c8-5-3-1-2-4-6(5)13(11,12)9-7(4)10/h1-3H,8H2,(H,9,10)
数据库引用编号
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tomohiro Osaki, Kazuo Azuma, Seiji Kurozumi, Yoshimori Takamori, Takeshi Tsuka, Tomohiro Imagawa, Yoshiharu Okamoto, Saburo Minami. Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs.
Marine drugs.
2012 Aug; 10(8):1873-82. doi:
10.3390/md10081873
. [PMID: 23015778] - H Wu, M Liu, S Wang, H Zhao, W Yao, W Feng, M Yan, Y Tang, M Wei. Comparative fasting bioavailability and pharmacokinetic properties of 2 formulations of glucosamine hydrochloride in healthy Chinese adult male volunteers.
Arzneimittel-Forschung.
2012 Aug; 62(8):367-71. doi:
10.1055/s-0032-1312650
. [PMID: 22791244] - Lucio C Rovati, Federica Girolami, Stefano Persiani. Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties.
Therapeutic advances in musculoskeletal disease.
2012 Jun; 4(3):167-80. doi:
10.1177/1759720x12437753
. [PMID: 22850875] - Kazuo Azuma, Tomohiro Osaki, Takeshi Tsuka, Tomohiro Imagawa, Yoshiharu Okamoto, Yoshimori Takamori, Saburo Minami. Effects of oral glucosamine hydrochloride administration on plasma free amino acid concentrations in dogs.
Marine drugs.
2011; 9(5):712-8. doi:
10.3390/md9050712
. [PMID: 21673884] - Sheng Zhong, Dafang Zhong, Xiaoyan Chen. Improved and simplified liquid chromatography/electrospray ionization mass spectrometry method for the analysis of underivatized glucosamine in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Jul; 854(1-2):291-8. doi:
10.1016/j.jchromb.2007.04.043
. [PMID: 17544344] - A Derfoul, A D Miyoshi, D E Freeman, R S Tuan. Glucosamine promotes chondrogenic phenotype in both chondrocytes and mesenchymal stem cells and inhibits MMP-13 expression and matrix degradation.
Osteoarthritis and cartilage.
2007 Jun; 15(6):646-55. doi:
10.1016/j.joca.2007.01.014
. [PMID: 17337215] - J F Lu-Suguro, J Hua, K Sakamoto, I Nagaoka. Inhibitory action of glucosamine on platelet activation in guinea pigs.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2005 Dec; 54(12):493-9. doi:
10.1007/s00011-005-1384-3
. [PMID: 16389570] - Kirsten M Neil, Michael W Orth, Paul M Coussens, Pooi-See Chan, John P Caron. Effects of glucosamine and chondroitin sulfate on mediators of osteoarthritis in cultured equine chondrocytes stimulated by use of recombinant equine interleukin-1beta.
American journal of veterinary research.
2005 Nov; 66(11):1861-9. doi:
10.2460/ajvr.2005.66.1861
. [PMID: 16334941] - J Hua, S Suguro, S Hirano, K Sakamoto, I Nagaoka. Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2005 Mar; 54(3):127-32. doi:
10.1007/s00011-004-1333-6
. [PMID: 15883746] - J Hua, S Suguro, K Iwabuchi, Y Tsutsumi-Ishii, K Sakamoto, I Nagaoka. Glucosamine, a naturally occurring amino monosaccharide, suppresses the ADP-mediated platelet activation in humans.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2004 Dec; 53(12):680-8. doi:
10.1007/s00011-004-1312-y
. [PMID: 15654516] - Jian Hua, Koji Sakamoto, Isao Nagaoka. Inhibitory actions of glucosamine, a therapeutic agent for osteoarthritis, on the functions of neutrophils.
Journal of leukocyte biology.
2002 Apr; 71(4):632-40. doi:
. [PMID: 11927650]