N,N-Diethyl-2-methylbenzamide (BioDeep_00000181382)

Main id: BioDeep_00000001143

 

human metabolite blood metabolite


代谢物信息卡片


N,N-Diethyl-2,5-dimethylbenzamide

化学式: C12H17NO (191.131)
中文名称: N,N-二乙基-2-甲基苯甲酰胺
谱图信息: 最多检出来源 Danio rerio(blood) 100%

分子结构信息

SMILES: CCN(CC)C(=O)C1=CC=CC=C1C
InChI: InChI=1S/C12H17NO/c1-4-13(5-2)12(14)11-9-7-6-8-10(11)3/h6-9H,4-5H2,1-3H3

描述信息

D010575 - Pesticides > D007302 - Insect Repellents
D020011 - Protective Agents
D016573 - Agrochemicals

同义名列表

13 个代谢物同义名

N,N-Diethyl-2,5-dimethylbenzamide; Benzamide,N,N-diethyl-2-methyl-; N,N Diethyl 3 methylbenzamide; N,N-Diethyl-2-methylbenzamide; N,N-Diethyl-3-methylbenzamide; N,N Diethyl m toluamide; N,N-Diethyl-m-toluamide; DEET, 2,5-di-me-analog; N,N Diethyltoluamide; N,N-Diethyltoluamide; DETA; Deet; DET



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Anais Le Mauff, Edmund J Norris, Andrew Y Li, Daniel R Swale. Repellent activity of essential oils to the Lone Star tick, Amblyomma americanum. Parasites & vectors. 2024 May; 17(1):202. doi: 10.1186/s13071-024-06246-0. [PMID: 38711138]
  • Lingling Ma, Tao Wu, Peiling Liu, Dongying Chen, Shengliang Cai, Hefeng Chen, Jingtao Zhou, Chaoyi Zhu, Shuang Li. Green Production of a High-value Mosquito Insecticide of Nootkatone from Seaweed Hydrolysates. Journal of agricultural and food chemistry. 2023 Dec; 71(48):18919-18927. doi: 10.1021/acs.jafc.3c06708. [PMID: 37991146]
  • Addison Ribeiro Almeida, Nicolas Dantas Oliveira, Francisco Ayrton Senna Domingos Pinheiro, Waldenice Alencar de Morais, Leandro De Santis Ferreira. Challenges encountered by natural repellents: Since obtaining until the final product. Pesticide biochemistry and physiology. 2023 Sep; 195(?):105538. doi: 10.1016/j.pestbp.2023.105538. [PMID: 37666610]
  • Jia Liu, Simin Ge, Peng Shao, Jianfeng Wang, Yanju Liu, Wei Wei, Can He, Lilan Zhang. Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China. Chemosphere. 2023 Jul; 339(?):139644. doi: 10.1016/j.chemosphere.2023.139644. [PMID: 37495050]
  • Cédric Akeumbiwo Tchumkam, Loick Pradel Kojom Foko, Cyrille Ndo, Estelle Essangui Same, Glwadys Cheteug Nguetsa, François Eya'Ane Meva, Lawrence Ayong, Carole Else Eboumbou Moukoko. Chemical composition and repellent activity of essential oils of Tithonia diversifolia (Asteraceae) leaves against the bites of Anopheles coluzzii. Scientific reports. 2023 04; 13(1):6001. doi: 10.1038/s41598-023-31791-6. [PMID: 37045885]
  • Maryani Paramita Astuti, Suprihanto Notodarmojo, Cindy Rianti Priadi, Lokesh P Padhye. Contaminants of emerging concerns (CECs) in a municipal wastewater treatment plant in Indonesia. Environmental science and pollution research international. 2023 Feb; 30(8):21512-21532. doi: 10.1007/s11356-022-23567-8. [PMID: 36272003]
  • Nieves R Colás-Ruiz, Frédérique Courant, Elena Gomez, Pablo A Lara-Martín, Miriam Hampel. Transcriptomic and metabolomic integration to assess the response of gilthead sea bream (Sparus aurata) exposed to the most used insect repellent: DEET. Environmental pollution (Barking, Essex : 1987). 2023 Jan; 316(Pt 2):120678. doi: 10.1016/j.envpol.2022.120678. [PMID: 36403875]
  • Immacolata Iovinella, Beniamino Caputo, Pietro Cobre, Mattia Manica, Alessandro Mandoli, Francesca Romana Dani. Advances in mosquito repellents: effectiveness of citronellal derivatives in laboratory and field trials. Pest management science. 2022 Dec; 78(12):5106-5112. doi: 10.1002/ps.7127. [PMID: 36102335]
  • Jeong Sik Choi, Yun Hwan Park, Sok Kim, Jino Son, Jaewon Park, Yoon-E Choi. Strategies to control the growth of cyanobacteria and recovery using adsorption and desorption. Bioresource technology. 2022 Dec; 365(?):128133. doi: 10.1016/j.biortech.2022.128133. [PMID: 36252763]
  • Jin-Xin Yu, Qian Xiang, Jia-Bao Qu, Yan-Min Hui, Tao Lin, Xin-Nian Zeng, Jia-Li Liu. Octopaminergic neurons function in appetitive but not aversive olfactory learning and memory in Bactrocera dorsalis. Insect science. 2022 Dec; 29(6):1747-1760. doi: 10.1111/1744-7917.13023. [PMID: 35189034]
  • Agustín Alvarez Costa, Paula V Gonzalez, Laura V Harburguer, Hector M Masuh. A rapid method for screening mosquito repellents on Anopheles pseudopunctipennis and Aedes aegypti. Parasitology research. 2022 Sep; 121(9):2713-2723. doi: 10.1007/s00436-022-07600-w. [PMID: 35867157]
  • Raziye Ergun, Cagri Akin Sekerci, Yiloren Tanidir, Naime İpek Ozturk, Tufan Tarcan, Selcuk Yucel. The results of three times repeated filling cystometry and pressure flow studies in children with non-neurogenic lower urinary tract dysfunction. Neurourology and urodynamics. 2022 06; 41(5):1157-1164. doi: 10.1002/nau.24934. [PMID: 35419875]
  • Wasana Boonyuan, Alex Ahebwa, Jirod Nararak, Sunaiyana Sathantriphop, Theeraphap Chareonviriyaphap. Enhanced Excito-Repellency of Binary Mixtures of Plant-Based Mosquito Repellents Against Culex quinquefasciatus Say (Diptera: Culicidae), a Night Biting Mosquito Species. Journal of medical entomology. 2022 05; 59(3):891-902. doi: 10.1093/jme/tjac002. [PMID: 35094070]
  • Vidhan Jain, Trilok Thomas, Sanjay Basak, Ravendra Kumar Sharma, Neeru Singh. Sequential dysregulated plasma levels of angiopoietins (ANG-2 and ratios of ANG-2/ANG-1) are associated with malaria severity and mortality among hospital admitted cases in South Bastar Region of Chhattisgarh, Central India. Pathogens and global health. 2022 Feb; 116(1):47-58. doi: 10.1080/20477724.2021.1953685. [PMID: 34308785]
  • Paula A Santos, Márcio R M DA Silva, Melanie Tavares, Eduardo Ricci-Junior. Microencapsulation of DEET in Solid Lipid Microparticles: production, characterization and safety evaluation. Anais da Academia Brasileira de Ciencias. 2022; 94(suppl 3):e20211166. doi: 10.1590/0001-3765202220211166. [PMID: 36074427]
  • Jiaqiao Zhang, Yan Yan, Hongjun Ni, Zhonghua Ni. Lung detection and severity prediction of pneumonia patients based on COVID-19 DET-PRE network. Expert review of medical devices. 2022 Jan; 19(1):97-106. doi: 10.1080/17434440.2022.2014319. [PMID: 34894969]
  • Cody W Koloski, Bryan J Cassone. Transcriptional profiling of Dermacentor variabilis (Acari: Ixodidae) provides insights into the role of the Haller's organ in spatial DEET recognition. Ticks and tick-borne diseases. 2022 01; 13(1):101827. doi: 10.1016/j.ttbdis.2021.101827. [PMID: 34610525]
  • Jennifer Hogenbom, Mouaz Istanbouli, Nicoletta Faraone. Novel β-Cyclodextrin and Catnip Essential Oil Inclusion Complex and Its Tick Repellent Properties. Molecules (Basel, Switzerland). 2021 Dec; 26(23):. doi: 10.3390/molecules26237391. [PMID: 34885973]
  • Valentina Pirota, Enrico Lunghi, Alessandra Benassi, Emmanuele Crespan, Mauro Freccero, Filippo Doria. Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26165025. [PMID: 34443620]
  • ". Insect repellents. The Medical letter on drugs and therapeutics. 2021 Jul; 63(1628):108-112. doi: ". [PMID: 34543260]
  • Xianhui Shi, Changlu Wang, James E Simon, William Reichert, Qingli Wu. Repellency of Novel Catnip Oils Against the Bed Bug (Hemiptera: Cimicidae). Journal of medical entomology. 2021 03; 58(2):528-534. doi: 10.1093/jme/tjaa218. [PMID: 33140831]
  • Colin Wong, Kylie Crystal, Joel Coats. Three molecules found in rosemary or nutmeg essential oils repel ticks (Dermacentor variabilis) more effectively than DEET in a no-human assay. Pest management science. 2021 Mar; 77(3):1348-1354. doi: 10.1002/ps.6149. [PMID: 33089620]
  • Jennifer L M Thorson, Daniel Beck, Millissia Ben Maamar, Eric E Nilsson, Michael K Skinner. Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease. Environmental health : a global access science source. 2020 11; 19(1):109. doi: 10.1186/s12940-020-00666-y. [PMID: 33148267]
  • Bhanu Shrestha, Youngseok Lee. Cellular and molecular mechanisms of DEET toxicity and disease-carrying insect vectors: a review. Genes & genomics. 2020 10; 42(10):1131-1144. doi: 10.1007/s13258-020-00991-z. [PMID: 32889681]
  • Zuhair M Haleem, Sandhya Yadav, Minor L Cushion, Rebecca J Tanner, Peter J Carek, Arch G Mainous. Exposure to N,N-Diethyl-Meta-Toluamide Insect Repellent and Human Health Markers: Population Based Estimates from the National Health and Nutrition Examination Survey. The American journal of tropical medicine and hygiene. 2020 08; 103(2):812-814. doi: 10.4269/ajtmh.20-0226. [PMID: 32458781]
  • Roger D Lawrie, Robert D Mitchell, Anirudh Dhammi, Andrew Wallace, Ernest Hodgson, R Michael Roe. Role of long non-coding RNA in DEET- and fipronil-mediated alteration of transcripts associated with Phase I and Phase II xenobiotic metabolism in human primary hepatocytes. Pesticide biochemistry and physiology. 2020 Jul; 167(?):104607. doi: 10.1016/j.pestbp.2020.104607. [PMID: 32527422]
  • Ali Afify, Christopher J Potter. Insect repellents mediate species-specific olfactory behaviours in mosquitoes. Malaria journal. 2020 Mar; 19(1):127. doi: 10.1186/s12936-020-03206-8. [PMID: 32228701]
  • Giovanni Benelli, Roman Pavela, Rianasoambolanoro Rakotosaona, Franks Kamgang Nzekoue, Angelo Canale, Marcello Nicoletti, Filippo Maggi. Insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of Hazomalania voyronii. Journal of ethnopharmacology. 2020 Feb; 248(?):112333. doi: 10.1016/j.jep.2019.112333. [PMID: 31654797]
  • Pingxi Xu, Fangfang Zeng, Robert H Bedoukian, Walter S Leal. DEET and other repellents are inhibitors of mosquito odorant receptors for oviposition attractants. Insect biochemistry and molecular biology. 2019 10; 113(?):103224. doi: 10.1016/j.ibmb.2019.103224. [PMID: 31446031]
  • S Jiang, L Yang, J R Bloomquist. High-throughput screening method for evaluating spatial repellency and vapour toxicity to mosquitoes. Medical and veterinary entomology. 2019 09; 33(3):388-396. doi: 10.1111/mve.12377. [PMID: 30907445]
  • Kaiming Tan, Gabriel B Faierstein, Pingxi Xu, Rosângela M R Barbosa, Garrison K Buss, Walter S Leal. A popular Indian clove-based mosquito repellent is less effective against Culex quinquefasciatus and Aedes aegypti than DEET. PloS one. 2019; 14(11):e0224810. doi: 10.1371/journal.pone.0224810. [PMID: 31689339]
  • Lindsay T Michalovicz, Alicia R Locker, Kimberly A Kelly, Julie V Miller, Zachary Barnes, Mary Ann Fletcher, Diane B Miller, Nancy G Klimas, Mariana Morris, Stephen M Lasley, James P O'Callaghan. Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness. Neurotoxicology. 2019 01; 70(?):26-32. doi: 10.1016/j.neuro.2018.10.006. [PMID: 30339781]
  • Samuel E Baker, Amanda Bishop Serafim, Pilar Morales-Agudelo, Meghan Vidal, Antonia M Calafat, Maria Ospina. Quantification of DEET and neonicotinoid pesticide biomarkers in human urine by online solid-phase extraction high-performance liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. 2019 Jan; 411(3):669-678. doi: 10.1007/s00216-018-1481-0. [PMID: 30483854]
  • John F Anderson, Francis J Ferrandino, Michael P Vasil, Robert H Bedoukian, Marie Maher, Karen McKenzie. Repellency of Naturally Occurring or Related Compounds, DEET, and Para-Menthane-3,8-Diol to Bed Bugs (Hemiptera: Cimicidae). Journal of medical entomology. 2018 05; 55(3):666-672. doi: 10.1093/jme/tjx253. [PMID: 29415167]
  • Penelope Goode, Lauren Ellse, Richard Wall. Preventing tick attachment to dogs using essential oils. Ticks and tick-borne diseases. 2018 05; 9(4):921-926. doi: 10.1016/j.ttbdis.2018.03.029. [PMID: 29606618]
  • Fangfang Zeng, Pingxi Xu, Kaiming Tan, Paulo H G Zarbin, Walter S Leal. Methyl dihydrojasmonate and lilial are the constituents with an 'off-label' insect repellence in perfumes. PloS one. 2018; 13(6):e0199386. doi: 10.1371/journal.pone.0199386. [PMID: 29920544]
  • Thalia R Segal, Lidia Mínguez-Alarcón, Yu-Han Chiu, Paige L Williams, Feiby L Nassan, Ramace Dadd, María Ospina, Antonia M Calafat, Russ Hauser. Urinary concentrations of 3-(diethylcarbamoyl)benzoic acid (DCBA), a major metabolite of N,N-diethyl-m-toluamide (DEET) and semen parameters among men attending a fertility center. Human reproduction (Oxford, England). 2017 Dec; 32(12):2532-2539. doi: 10.1093/humrep/dex327. [PMID: 29077936]
  • Robert D Mitchell, Andrew D Wallace, Ernest Hodgson, R Michael Roe. Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure. International journal of molecular sciences. 2017 10; 18(10):. doi: 10.3390/ijms18102104. [PMID: 28991164]
  • Wasana Boonyuan, Sunaiyana Sathantriphop, Krajana Tainchum, Vithee Muenworn, Atchariya Prabaripai, Michael J Bangs, Theeraphap Chareonviriyaphap. Insecticidal and Behavioral Avoidance Responses of Anopheles minimus and Culex quinquefasciatus (Diptera: Culicidae) to Three Synthetic Repellents. Journal of medical entomology. 2017 09; 54(5):1312-1322. doi: 10.1093/jme/tjx081. [PMID: 28419272]
  • Albert Kimutai, Moses Ngeiywa, Margaret Mulaa, Peter G N Njagi, Johnstone Ingonga, Lydia B Nyamwamu, Cyprian Ombati, Philip Ngumbi. Repellent effects of the essential oils of Cymbopogon citratus and Tagetes minuta on the sandfly, Phlebotomus duboscqi. BMC research notes. 2017 Feb; 10(1):98. doi: 10.1186/s13104-017-2396-0. [PMID: 28202077]
  • Cameron E Webb, Isabel Mr Hess. A review of recommendations on the safe and effective use of topical mosquito repellents. Public health research & practice. 2016 Dec; 26(5):. doi: 10.17061/phrp2651657. [PMID: 27997936]
  • Eugene K Blythe, Nurhayat Tabanca, Betul Demirci, Maia Tsikolia, Jeffrey R Bloomquist, Ulrich R Bernier. Lantana montevidensis Essential Oil: Chemical Composition and Mosquito Repellent Activity against Aedes aegypti. Natural product communications. 2016 Nov; 11(11):1713-1716. doi: . [PMID: 30475514]
  • A K Murchie, S Clawson, I Rea, I W N Forsythe, A W Gordon, S Jess. DEET (N,N-diethyl-meta-toluamide)/PMD (para-menthane-3,8-diol) repellent-treated mesh increases Culicoides catches in light traps. Parasitology research. 2016 Sep; 115(9):3543-9. doi: 10.1007/s00436-016-5119-x. [PMID: 27179956]
  • Valentín Uc-Puc, Josué Herrera-Bojórquez, Carolina Carmona-Carballo, Azael Che-Mendoza, Anuar Medina-Barreiro, Juan Chablé-Santos, Juan I Arredondo-Jiménez, Adriana E Flores-Suárez, Pablo Manrique-Saide. [Effectiveness of commercial repellents against Aedes aegypti (L.) in Yucatan, México]. Salud publica de Mexico. 2016 Aug; 58(4):472-5. doi: . [PMID: 27599081]
  • Antonia M Calafat, Samuel E Baker, Lee-Yang Wong, Amanda M Bishop, Pilar Morales-A, Liza Valentin-Blasini. Novel exposure biomarkers of N,N-diethyl-m-toluamide (DEET): Data from the 2007-2010 National Health and Nutrition Examination Survey. Environment international. 2016 Jul; 92-93(?):398-404. doi: 10.1016/j.envint.2016.04.021. [PMID: 27138630]
  • Diana Campos, Carlos Gravato, Carla Quintaneiro, Olga Koba, Tomas Randak, Amadeu M V M Soares, João L T Pestana. Are insect repellents toxic to freshwater insects? A case study using caddisflies exposed to DEET. Chemosphere. 2016 Apr; 149(?):177-82. doi: 10.1016/j.chemosphere.2016.01.098. [PMID: 26855222]
  • Diana Campos, Carlos Gravato, Carla Quintaneiro, Amadeu M V M Soares, João L T Pestana. Responses of the aquatic midge Chironomus riparius to DEET exposure. Aquatic toxicology (Amsterdam, Netherlands). 2016 Mar; 172(?):80-5. doi: 10.1016/j.aquatox.2015.12.020. [PMID: 26773354]
  • Temitope F Adams, Chatchawal Wongchai, Anchalee Chaidee, Wolfgang Pfeiffer. 'Singing in the Tube'--audiovisual assay of plant oil repellent activity against mosquitoes (Culex pipiens). Parasitology research. 2016 Jan; 115(1):225-39. doi: 10.1007/s00436-015-4739-x. [PMID: 26412058]
  • Nutthanun Auysawasdi, Sawitri Chuntranuluck, Siriporn Phasomkusolsil, Vichien Keeratinijakal. Improving the effectiveness of three essential oils against Aedes aegypti (Linn.) and Anopheles dirus (Peyton and Harrison). Parasitology research. 2016 Jan; 115(1):99-106. doi: 10.1007/s00436-015-4725-3. [PMID: 26358103]
  • Sunaiyana Sathantriphop, Nicole L Achee, Unchalee Sanguanpong, Theeraphap Chareonviriyaphap. The effects of plant essential oils on escape response and mortality rate of Aedes aegypti and Anopheles minimus. Journal of vector ecology : journal of the Society for Vector Ecology. 2015 Dec; 40(2):318-26. doi: 10.1111/jvec.12170. [PMID: 26611967]
  • Tran Trung Hieu, Won Sil Choi, Soon-Il Kim, Mo Wang, Young-Joon Ahn. Enhanced repellency of binary mixtures of Calophyllum inophyllum nut oil fatty acids or their esters and three terpenoids to Stomoxys calcitrans. Pest management science. 2015 Sep; 71(9):1213-8. doi: 10.1002/ps.3904. [PMID: 25204729]
  • Anthony S Malamas, Erlei Jin, Qi Zhang, John Haaga, Zheng-Rong Lu. Anti-angiogenic Effects of Bumetanide Revealed by DCE-MRI with a Biodegradable Macromolecular Contrast Agent in a Colon Cancer Model. Pharmaceutical research. 2015 Sep; 32(9):3029-43. doi: 10.1007/s11095-015-1684-4. [PMID: 25840948]
  • Ephrem Abiy, Teshome Gebre-Michael, Meshesha Balkew, Girmay Medhin. Repellent efficacy of DEET, MyggA, neem (Azedirachta indica) oil and chinaberry (Melia azedarach) oil against Anopheles arabiensis, the principal malaria vector in Ethiopia. Malaria journal. 2015 May; 14(?):187. doi: 10.1186/s12936-015-0705-4. [PMID: 25935845]
  • Lih-Ming Yiin, Jia-Ni Tian, Chien-Che Hung. Assessment of dermal absorption of DEET-containing insect repellent and oxybenzone-containing sunscreen using human urinary metabolites. Environmental science and pollution research international. 2015 May; 22(9):7062-70. doi: 10.1007/s11356-014-3915-3. [PMID: 25491253]
  • Sylvain Merel, Andrey I Nikiforov, Shane A Snyder. Potential analytical interferences and seasonal variability in diethyltoluamide environmental monitoring programs. Chemosphere. 2015 May; 127(?):238-45. doi: 10.1016/j.chemosphere.2015.02.025. [PMID: 25748344]
  • S H Thany, F Tong, J R Bloomquist. Pre-treatment of Stegomyia aegypti mosquitoes with a sublethal dose of imidacloprid impairs behavioural avoidance induced by lemon oil and DEET. Medical and veterinary entomology. 2015 Mar; 29(1):99-103. doi: 10.1111/mve.12082. [PMID: 25155403]
  • Cameron E Webb. Are we doing enough to promote the effective use of mosquito repellents?. The Medical journal of Australia. 2015 Feb; 202(3):128-9. doi: 10.5694/mja14.01237. [PMID: 25669466]
  • Aly Abd-Ella, Maria Stankiewicz, Karolina Mikulska, Wieslaw Nowak, Cédric Pennetier, Mathilde Goulu, Carole Fruchart-Gaillard, Patricia Licznar, Véronique Apaire-Marchais, Olivier List, Vincent Corbel, Denis Servent, Bruno Lapied. The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases. PloS one. 2015; 10(5):e0126406. doi: 10.1371/journal.pone.0126406. [PMID: 25961834]
  • Kuo-Lin Huang, Te-San Chen, Pi-Hui Chen, Yi-Ming Kuo. Degradation of N,N-diethyl-m-toluamid (DEET) on lead dioxide electrodes in different environmental aqueous matrixes. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2015; 50(9):931-40. doi: 10.1080/10934529.2015.1030286. [PMID: 26061206]
  • Ryan C Lewis, David E Cantonwine, Liza V Anzalota Del Toro, Antonia M Calafat, Liza Valentin-Blasini, Mark D Davis, Samuel E Baker, Akram N Alshawabkeh, José F Cordero, John D Meeker. Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico. Environmental health : a global access science source. 2014 Nov; 13(?):97. doi: 10.1186/1476-069x-13-97. [PMID: 25409771]
  • Pingxi Xu, Young-Moo Choo, Alyssa De La Rosa, Walter S Leal. Mosquito odorant receptor for DEET and methyl jasmonate. Proceedings of the National Academy of Sciences of the United States of America. 2014 Nov; 111(46):16592-7. doi: 10.1073/pnas.1417244111. [PMID: 25349401]
  • Devin Wiles, Justin Yee, Uvidelio Castillo, Jason Russell, Henry Spiller, Marcel Casavant. A lethal case of DEET toxicity due to intentional ingestion. Journal of analytical toxicology. 2014 Nov; 38(9):696-8. doi: 10.1093/jat/bku082. [PMID: 25002457]
  • Ubol Phukerd, Mayura Soonwera. Repellency of essential oils extracted from Thai native plants against Aedes aegypti (Linn.) and Culex quinquefasciatus (Say). Parasitology research. 2014 Sep; 113(9):3333-40. doi: 10.1007/s00436-014-3996-4. [PMID: 25088471]
  • Jodi M Scott, Tanjim Hossain, Claudia Davidson, Michael L Smith, Rui-De Xue. Laboratory evaluation of citronella, picaridin, and deet repellents against Psorophora ciliata and Psorophora howardii. Journal of the American Mosquito Control Association. 2014 Jun; 30(2):136-7. doi: 10.2987/13-6368.1. [PMID: 25102599]
  • Haribalan Perumalsamy, Jae Yeon Kim, Jun-Ran Kim, Kum Na Ra Hwang, Young-Joon Ahn. Toxicity of basil oil constituents and related compounds and the efficacy of spray formulations to Dermatophagoides farinae (Acari: Pyroglyphidae). Journal of medical entomology. 2014 May; 51(3):650-7. doi: 10.1603/me13235. [PMID: 24897858]
  • Immacolata Iovinella, Paolo Pelosi, Barbara Conti. A rationale to design longer lasting mosquito repellents. Parasitology research. 2014 May; 113(5):1813-20. doi: 10.1007/s00436-014-3827-7. [PMID: 24599300]
  • Mostafa I Hassan, Mohamad A Fouda, Kotb M Hammad, Mohamad A Tanani, Ahmed Z Shehata. Repellent effect of Lagenaria siceraria extracts against Culex pipiens. Journal of the Egyptian Society of Parasitology. 2014 Apr; 44(1):243-8. doi: 10.12816/0006464. [PMID: 24961030]
  • J H Raymer, W B Studabaker, M Gardner, J Talton, S A Quandt, H Chen, L C Michael, M McCombs, T A Arcury. Pesticide exposures to migrant farmworkers in Eastern NC: detection of metabolites in farmworker urine associated with housing violations and camp characteristics. American journal of industrial medicine. 2014 Mar; 57(3):323-37. doi: 10.1002/ajim.22284. [PMID: 24273087]
  • S P Frances, L M Rigby, W K Chow. Comparative laboratory and field evaluation of repellent formulations containing deet and lemon eucalyptus oil against mosquitoes in Queensland, Australia. Journal of the American Mosquito Control Association. 2014 Mar; 30(1):65-7. doi: 10.2987/13-6366.1. [PMID: 24772681]
  • Frédéric Pages, Hans Dautel, Gérard Duvallet, Olaf Kahl, Ludovic de Gentile, Nathalie Boulanger. Tick repellents for human use: prevention of tick bites and tick-borne diseases. Vector borne and zoonotic diseases (Larchmont, N.Y.). 2014 Feb; 14(2):85-93. doi: 10.1089/vbz.2013.1410. [PMID: 24410143]
  • B W Bissinger, J P Schmidt, J J Owens, S M Mitchell, M K Kennedy. Activity of the plant-based repellent, TT-4302 against the ticks Amblyomma americanum, Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus (Acari: Ixodidae). Experimental & applied acarology. 2014 Jan; 62(1):105-13. doi: 10.1007/s10493-013-9719-1. [PMID: 23907554]
  • Andrea Slaninova, Helena Modra, Martin Hostovsky, Eliska Sisperova, Jana Blahova, Iveta Matejova, Monika Vicenova, Martin Faldyna, Lenka Zelnickova, Frantisek Tichy, Zdenka Svobodova. Effects of subchronic exposure to N,N-diethyl-m-toluamide on selected biomarkers in common carp (Cyprinus carpio L.). BioMed research international. 2014; 2014(?):828515. doi: 10.1155/2014/828515. [PMID: 24795897]
  • Jia-Ni Tian, Lih-Ming Yiin. Urinary metabolites of DEET after dermal application on child and adult subjects. Journal of environmental health. 2014 Jan; 76(6):162-9. doi: NULL. [PMID: 24645428]
  • Changlu Wang, Lihua Lü, Aijun Zhang, Chaofeng Liu. Repellency of selected chemicals against the bed bug (Hemiptera: Cimicidae). Journal of economic entomology. 2013 Dec; 106(6):2522-9. doi: 10.1603/ec13155. [PMID: 24498754]
  • Kumudini M Meepagala, Ulrich R Bernier, Charles Burandt, Stephen O Duke. Mosquito repellents based on a natural chromene analogue with longer duration of action than N,N-diethyl-meta-toluamide (DEET). Journal of agricultural and food chemistry. 2013 Oct; 61(39):9293-7. doi: 10.1021/jf402635z. [PMID: 24006960]
  • H Wu, C C Fu, D D Yu, J T Feng, X Zhang, Z Q Ma. Repellent activity screening of 11 kinds of essential oils against Aedes albopictus Skuse: microcapsule preparation of Herba Schizonepetae oil and repellent bioassay on hand skin. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2013 Aug; 107(8):471-9. doi: 10.1093/trstmh/trt045. [PMID: 23740242]
  • Peter Kuklenyik, Samuel E Baker, Amanda M Bishop, Pilar Morales-A, Antonia M Calafat. On-line solid phase extraction-high performance liquid chromatography-isotope dilution-tandem mass spectrometry approach to quantify N,N-diethyl-m-toluamide and oxidative metabolites in urine. Analytica chimica acta. 2013 Jul; 787(?):267-73. doi: 10.1016/j.aca.2013.05.055. [PMID: 23830449]
  • Trine Eggen, Eldbjørg S Heimstad, Arne O Stuanes, Hans Ragnar Norli. Uptake and translocation of organophosphates and other emerging contaminants in food and forage crops. Environmental science and pollution research international. 2013 Jul; 20(7):4520-31. doi: 10.1007/s11356-012-1363-5. [PMID: 23250727]
  • M D Wilson, M Osei-Atweneboana, D A Boakye, I Osei-Akoto, E Obuobi, C Wiafe, A Kiszewski. Efficacy of DEET and non-DEET-based insect repellents against bites of Simulium damnosum vectors of onchocerciasis. Medical and veterinary entomology. 2013 Jun; 27(2):226-31. doi: 10.1111/j.1365-2915.2012.01054.x. [PMID: 23167529]
  • Stefan Trapp, Trine Eggen. Simulation of the plant uptake of organophosphates and other emerging pollutants for greenhouse experiments and field conditions. Environmental science and pollution research international. 2013 Jun; 20(6):4018-29. doi: 10.1007/s11356-012-1337-7. [PMID: 23212267]
  • Nurhayat Tabanca, Mei Wang, Cristina Avonto, Amar G Chittiboyina, Jon F Parcher, John F Carroll, Matthew Kramer, Ikhlas A Khan. Bioactivity-guided investigation of geranium essential oils as natural tick repellents. Journal of agricultural and food chemistry. 2013 May; 61(17):4101-7. doi: 10.1021/jf400246a. [PMID: 23528036]
  • J A Terriquez, S A Klotz, E A Meister, J H Klotz, J O Schmidt. Repellency of DEET, picaridin, and three essential oils to Triatoma rubida (Hemiptera: Reduviidae: Triatominae). Journal of medical entomology. 2013 May; 50(3):664-7. doi: 10.1603/me12282. [PMID: 23802464]
  • K R Chauhan, J R Aldrich, P W McCardle, G B White, R E Webb. A field bioassay to evaluate potential spatial repellents against natural mosquito populations. Journal of the American Mosquito Control Association. 2012 Dec; 28(4):301-6. doi: 10.2987/11-6199r.1. [PMID: 23393752]
  • Mohan Manikkam, Rebecca Tracey, Carlos Guerrero-Bosagna, Michael K Skinner. Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations. Reproductive toxicology (Elmsford, N.Y.). 2012 Dec; 34(4):708-19. doi: 10.1016/j.reprotox.2012.08.010. [PMID: 22975477]
  • Laila Abdullah, James E Evans, Alex Bishop, Jon M Reed, Gogce Crynen, John Phillips, Robert Pelot, Myles A Mullan, Austin Ferro, Christopher M Mullan, Michael J Mullan, Ghania Ait-Ghezala, Fiona C Crawford. Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents. Neuromolecular medicine. 2012 Dec; 14(4):349-61. doi: 10.1007/s12017-012-8192-z. [PMID: 22798222]
  • Chanda Vongsombath, Katinka Pålsson, Lars Björk, Anna-Karin Borg-Karlson, Thomas G T Jaenson. Mosquito (Diptera: Culicidae) repellency field tests of essential oils from plants traditionally used in Laos. Journal of medical entomology. 2012 Nov; 49(6):1398-404. doi: 10.1603/me12025. [PMID: 23270168]
  • Daryl J Fediuk, Tao Wang, Yufei Chen, Fiona E Parkinson, Michael P Namaka, Keith J Simons, Frank J Burczynski, Xiaochen Gu. Metabolic disposition of the insect repellent DEET and the sunscreen oxybenzone following intravenous and skin administration in rats. International journal of toxicology. 2012 Sep; 31(5):467-76. doi: 10.1177/1091581812459893. [PMID: 23064701]
  • J J Zhu, D R Berkebile, C A Dunlap, A Zhang, D Boxler, K Tangtrakulwanich, R W Behle, F Baxendale, G Brewer. Nepetalactones from essential oil of Nepeta cataria represent a stable fly feeding and oviposition repellent. Medical and veterinary entomology. 2012 Jun; 26(2):131-8. doi: 10.1111/j.1365-2915.2011.00972.x. [PMID: 21781140]
  • Jonathan D Bohbot, Joseph C Dickens. Odorant receptor modulation: ternary paradigm for mode of action of insect repellents. Neuropharmacology. 2012 Apr; 62(5-6):2086-95. doi: 10.1016/j.neuropharm.2012.01.004. [PMID: 22269900]
  • J A Weeks, P D Guiney, A I Nikiforov. Assessment of the environmental fate and ecotoxicity of N,N-diethyl-m-toluamide (DEET). Integrated environmental assessment and management. 2012 Jan; 8(1):120-34. doi: 10.1002/ieam.1246. [PMID: 22006575]
  • Dallas Aronson, John Weeks, Bill Meylan, Patrick D Guiney, Philip H Howard. Environmental release, environmental concentrations, and ecological risk of N,N-Diethyl-m-toluamide (DEET). Integrated environmental assessment and management. 2012 Jan; 8(1):135-66. doi: 10.1002/ieam.271. [PMID: 21913321]
  • Fitsum Fikru Dube, Kassahun Tadesse, Göran Birgersson, Emiru Seyoum, Habte Tekie, Rickard Ignell, Sharon R Hill. Fresh, dried or smoked? Repellent properties of volatiles emitted from ethnomedicinal plant leaves against malaria and yellow fever vectors in Ethiopia. Malaria journal. 2011 Dec; 10(?):375. doi: 10.1186/1475-2875-10-375. [PMID: 22182798]
  • Whitney A Qualls, Rui-De Xue, J Adam Holt, Mike L Smith, Jeanne J Moeller. Field evaluation of commercial repellents against the floodwater mosquito Psorophora columbiae (Diptera: Culicidae) in St. Johns County, Florida. Journal of medical entomology. 2011 Nov; 48(6):1247-9. doi: 10.1603/me11072. [PMID: 22238886]
  • Daryl J Fediuk, Tao Wang, Yufei Chen, Fiona E Parkinson, Michael P Namaka, Keith J Simons, Frank J Burczynski, Xiaochen Gu. Tissue disposition of the insect repellent DEET and the sunscreen oxybenzone following intravenous and topical administration in rats. Biopharmaceutics & drug disposition. 2011 Oct; 32(7):369-79. doi: 10.1002/bdd.765. [PMID: 21812003]
  • C Kongkaew, I Sakunrag, N Chaiyakunapruk, A Tawatsin. Effectiveness of citronella preparations in preventing mosquito bites: systematic review of controlled laboratory experimental studies. Tropical medicine & international health : TM & IH. 2011 Jul; 16(7):802-10. doi: 10.1111/j.1365-3156.2011.02781.x. [PMID: 21481108]
  • Marlies Van de Wouwer, Sabine André, Hans-J Gabius, Antonio Villalobo. Nitric oxide changes distinct aspects of the glycophenotype of human neuroblastoma NB69 cells. Nitric oxide : biology and chemistry. 2011 Mar; 24(2):91-101. doi: 10.1016/j.niox.2010.12.007. [PMID: 21182976]
  • Michael A Birkett, Ahmed Hassanali, Solveig Hoglund, Jan Pettersson, John A Pickett. Repellent activity of catmint, Nepeta cataria, and iridoid nepetalactone isomers against Afro-tropical mosquitoes, ixodid ticks and red poultry mites. Phytochemistry. 2011 Jan; 72(1):109-14. doi: 10.1016/j.phytochem.2010.09.016. [PMID: 21056438]
  • Azima Laili Hanifah, Siti Hazar Awang Ismail, Ho Tze Ming. Laboratory evaluation of four commercial repellents against larval Leptotrombidium deliense (Acari: Trombiculidae). The Southeast Asian journal of tropical medicine and public health. 2010 Sep; 41(5):1082-7. doi: ". [PMID: 21073028]
  • Dawn Reinhold, Saritha Vishwanathan, Jung Jae Park, David Oh, F Michael Saunders. Assessment of plant-driven removal of emerging organic pollutants by duckweed. Chemosphere. 2010 Aug; 80(7):687-92. doi: 10.1016/j.chemosphere.2010.05.045. [PMID: 20580410]