1H-Imidazole, nitro- (BioDeep_00000173058)

Main id: BioDeep_00000009958

 

human metabolite blood metabolite


代谢物信息卡片


1-nitro-1H-imidazole

化学式: C3H3N3O2 (113.0225)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(not specific) 50%

分子结构信息

SMILES: C1=CN(C=N1)[N+](=O)[O-]
InChI: InChI=1S/C3H3N3O2/c7-6(8)5-2-1-4-3-5/h1-3H

描述信息

同义名列表

3 个代谢物同义名

1-nitro-1H-imidazole; 1H-Imidazole, nitro-; nitroimidazole



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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  • Jason M Swoger, Miguel Regueiro. Preventive therapy in postoperative Crohn's disease. Current opinion in gastroenterology. 2010 Jul; 26(4):337-43. doi: 10.1097/mog.0b013e328338f724. [PMID: 20571386]
  • Cristina Mahugo-Santana, Zoraida Sosa-Ferrera, Ma Esther Torres-Padrón, José Juan Santana-Rodríguez. Analytical methodologies for the determination of nitroimidazole residues in biological and environmental liquid samples: a review. Analytica chimica acta. 2010 Apr; 665(2):113-22. doi: 10.1016/j.aca.2010.03.022. [PMID: 20417321]
  • C P Lee, G S Payne, A Oregioni, R Ruddle, S Tan, F I Raynaud, D Eaton, M J Campbell, K Cross, G Halbert, M Tracy, J McNamara, B Seddon, M O Leach, P Workman, I Judson. A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy. British journal of cancer. 2009 Dec; 101(11):1860-8. doi: 10.1038/sj.bjc.6605425. [PMID: 19935799]
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  • Mark Cronly, Patrice Behan, Barry Foley, Edward Malone, Liam Regan. Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 May; 877(14-15):1494-500. doi: 10.1016/j.jchromb.2009.03.030. [PMID: 19345159]
  • Colin S Thompson, Imelda M Traynor, Terence L Fodey, Steven R H Crooks. Improved screening method for the detection of a range of nitroimidazoles in various matrices by optical biosensor. Analytica chimica acta. 2009 Apr; 637(1-2):259-64. doi: 10.1016/j.aca.2008.09.040. [PMID: 19286038]
  • Ming-gen Yang, Xiao-kun Zhao, Zhi-ping Wu, Ning Xiao, Chen Lü, Yi Hou. [Meta-analysis of antibiotic prophylaxis for postoperative bacteriuria in patients undergoing transrectal prostatic biopsy]. Zhonghua yi xue za zhi. 2009 Feb; 89(4):254-9. doi: NULL. [PMID: 19552843]
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  • Dorota Olender, Justyna Zwawiak, Victor Lukianchuk, Roman Lesyk, Aleksandra Kropacz, Andrzej Fojutowski, Lucjusz Zaprutko. Synthesis of some N-substituted nitroimidazole derivatives as potential antioxidant and antifungal agents. European journal of medicinal chemistry. 2009 Feb; 44(2):645-52. doi: 10.1016/j.ejmech.2008.05.016. [PMID: 18590938]
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  • Murat Muhsin Muhip Harputluoglu, U Demirel, N Karadag, D Karahan, M Aladag, M Karincaoglu, F Hilmioglu. Severe hepatitis with prolonged cholestasis and bile duct injury due the long-term use of ornidazole. Acta gastro-enterologica Belgica. 2007 Jul; 70(3):293-5. doi: NULL. [PMID: 18074740]
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  • Stéphanie Fraselle, Veerle Derop, Jean-Marie Degroodt, Joris Van Loco. Validation of a method for the detection and confirmation of nitroimidazoles and the corresponding hydroxy metabolites in pig plasma by high performance liquid chromatography-tandem mass spectrometry. Analytica chimica acta. 2007 Mar; 586(1-2):383-93. doi: 10.1016/j.aca.2007.01.009. [PMID: 17386738]
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  • Tao Ding, Jinzhong Xu, Chongyu Shen, Yuan Jiang, Huilan Chen, Bin Wu, Zengyun Zhao, Gonghai Li, Jing Zhang, Fei Liu. [Determination of three nitroimidazole residues in royal jelly by high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2006 Jul; 24(4):331-4. doi: ". [PMID: 17017153]
  • Daniel D Rossouw, Mattheus G Lötter, Hanlie du Raan, Susara E Jansen, Alexander Höhn, Ben V Burger. Radiosynthesis and evaluation of two novel 123I-labeled 2-methyl-4-nitroimidazole derivatives as potential infection imaging agents. Nuclear medicine and biology. 2005 May; 32(4):385-94. doi: 10.1016/j.nucmedbio.2005.02.001. [PMID: 15878508]
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  • H Barthel, H Wilson, D R Collingridge, G Brown, S Osman, S K Luthra, F Brady, P Workman, P M Price, E O Aboagye. In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography. British journal of cancer. 2004 Jun; 90(11):2232-42. doi: 10.1038/sj.bjc.6601862. [PMID: 15150578]
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