1-(Carboxyethylthio)tetradecane (BioDeep_00000172127)
human metabolite blood metabolite
代谢物信息卡片
化学式: C17H34O2S (302.2279)
中文名称: 3-(十四烷基硫基)丙酸
谱图信息:
最多检出来源 Homo sapiens(blood) 14.29%
分子结构信息
SMILES: CCCCCCCCCCCCCCSCCC(=O)O
InChI: InChI=1S/C17H34O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-20-16-14-17(18)19/h2-16H2,1H3,(H,18,19)
数据库引用编号
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Rolf K Berge, Daniel Cacabelos, Rosa Señarís, Jan Erik Nordrehaug, Ottar Nygård, Jon Skorve, Bodil Bjørndal. Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio.
Lipids in health and disease.
2020 May; 19(1):94. doi:
10.1186/s12944-020-01271-1. [PMID: 32410680] - Rolf K Berge, Bodil Bjørndal, Elin Strand, Pavol Bohov, Carine Lindquist, Jan Erik Nordrehaug, Asbjørn Svardal, Jon Skorve, Ottar Nygård. Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice.
Lipids in health and disease.
2016 Feb; 15(?):24. doi:
10.1186/s12944-016-0192-9. [PMID: 26846427] - Nataša Nikolić, Magdalena Rhedin, Arild C Rustan, Len Storlien, G Hege Thoresen, Maria Strömstedt. Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells.
Biochemistry research international.
2012; 2012(?):714074. doi:
10.1155/2012/714074. [PMID: 21904680] - Rolf K Berge, Jon Skorve, Karl Johan Tronstad, Kjetil Berge, Oddrun Anita Gudbrandsen, Hans Grav. Metabolic effects of thia fatty acids.
Current opinion in lipidology.
2002 Jun; 13(3):295-304. doi:
10.1097/00041433-200206000-00010. [PMID: 12045400] - D K Asiedu, A Demoz, J Skorve, H J Grav, R K Berge. Acute modulation of rat hepatic lipid metabolism by sulphur-substituted fatty acid analogues.
Biochemical pharmacology.
1995 Mar; 49(7):1013-22. doi:
10.1016/0006-2952(94)00460-4. [PMID: 7741757] - D K Asiedu, A al-Shurbaji, A C Rustan, I Björkhem, L Berglund, R K Berge. Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids.
European journal of biochemistry.
1995 Feb; 227(3):715-22. doi:
10.1111/j.1432-1033.1995.tb20193.x. [PMID: 7867630] - S Skrede, P Wu, H Osmundsen. Effects of tetradecylthiopropionic acid and tetradecylthioacrylic acid on rat liver lipid metabolism.
The Biochemical journal.
1995 Jan; 305 ( Pt 2)(?):591-7. doi:
10.1042/bj3050591. [PMID: 7832778] - H J Grav, D K Asiedu, R K Berge. Gas chromatographic measurement of 3- and 4-thia fatty acids incorporated into various classes of rat liver lipids during feeding experiments.
Journal of chromatography. B, Biomedical applications.
1994 Aug; 658(1):1-10. doi:
10.1016/0378-4347(94)00224-x. [PMID: 7952108] - A Demoz, A Svardal, R K Berge. Relationship between peroxisome-proliferating sulfur-substituted fatty acid analogs, hepatic lipid peroxidation and hydrogen peroxide metabolism.
Biochemical pharmacology.
1993 Jan; 45(1):257-9. doi:
10.1016/0006-2952(93)90400-q. [PMID: 8424818] - H Kryvi, A Aarsland, R K Berge. Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria.
Journal of structural biology.
1990 May; 103(3):257-65. doi:
10.1016/1047-8477(90)90044-d. [PMID: 2261310] - R K Berge, A Aarsland, H Kryvi, J Bremer, N Aarsaether. Alkylthio acetic acids (3-thia fatty acids)--a new group of non-beta-oxidizable peroxisome-inducing fatty acid analogues--II. Dose-response studies on hepatic peroxisomal- and mitochondrial changes and long-chain fatty acid metabolizing enzymes in rats.
Biochemical pharmacology.
1989 Nov; 38(22):3969-79. doi:
10.1016/0006-2952(89)90676-x. [PMID: 2574577] - A Aarsland, N Aarsaether, J Bremer, R K Berge. Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the induction of peroxisomal beta-oxidation.
Journal of lipid research.
1989 Nov; 30(11):1711-8. doi:
. [PMID: 2614273]
