Dextrothyroxine (BioDeep_00000033240)
Main id: BioDeep_00000001625
human metabolite PANOMIX_OTCML-2023 blood metabolite
代谢物信息卡片
(2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
化学式: C15H11I4NO4 (776.6867)
中文名称: D-甲状腺素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N
InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m1/s1
描述信息
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism. [PubChem]
C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1553 - Thyroid Agent
D-Thyroxine (D-T4) is a thyroid hormone that can inhibit TSH secretion. D-Thyroxine can be used for the research of hypercholesterolemia[1][2].
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:30659
- PubChem: 8730
- HMDB: HMDB0014651
- DrugBank: DB00509
- ChEMBL: CHEMBL559
- Wikipedia: Dextrothyroxine
- MeSH: Dextrothyroxine
- chemspider: 8402
- CAS: 51-49-0
- medchemexpress: HY-A0152
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
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COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yanjun Wang, Ping Guo, Lu Liu, Yanan Zhang, Ping Zeng, Zhongshang Yuan. Mendelian Randomization Highlights the Causal Role of Normal Thyroid Function on Blood Lipid Profiles.
Endocrinology.
2021 05; 162(5):. doi:
10.1210/endocr/bqab037. [PMID: 33587120] - Christopher Hine, Hyo-Jeong Kim, Yan Zhu, Eylul Harputlugil, Alban Longchamp, Marina Souza Matos, Preeti Ramadoss, Kevin Bauerle, Lear Brace, John M Asara, C Keith Ozaki, Sheue-Yann Cheng, Subhankar Singha, Kyo Han Ahn, Alec Kimmelman, Ffolliott M Fisher, Pavlos Pissios, Dominic J Withers, Colin Selman, Rui Wang, Kelvin Yen, Valter D Longo, Pinchas Cohen, Andrzej Bartke, John J Kopchick, Richard Miller, Anthony N Hollenberg, James R Mitchell. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.
Cell metabolism.
2017 Jun; 25(6):1320-1333.e5. doi:
10.1016/j.cmet.2017.05.003. [PMID: 28591635] - Simon H S Pearce, Salman Razvi, Mohammad E Yadegarfar, Carmen Martin-Ruiz, Andrew Kingston, Joanna Collerton, Theo J Visser, Tom B Kirkwood, Carol Jagger. Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study.
The Journal of clinical endocrinology and metabolism.
2016 11; 101(11):4385-4394. doi:
10.1210/jc.2016-1935. [PMID: 27552542] - Shuai Yang, Feng-Tao Shi, Peter C K Leung, He-Feng Huang, Jianxia Fan. Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus.
The Journal of clinical endocrinology and metabolism.
2016 11; 101(11):4237-4243. doi:
10.1210/jc.2016-1506. [PMID: 27583471] - Tolga Unüvar, Ahmet Anık, Gönül Catlı, Ihsan Esen, Ayhan Abacı, Atilla Büyükgebiz, Ece Böber. Isolated hyperthyrotropinemia in childhood obesity and its relation with metabolic parameters.
Journal of endocrinological investigation.
2014 Sep; 37(9):799-804. doi:
10.1007/s40618-014-0100-y. [PMID: 24920280] - Rolf Bambauer, Carolin Bambauer, Boris Lehmann, Reinhard Latza, Ralf Schiel. LDL-apheresis: technical and clinical aspects.
TheScientificWorldJournal.
2012; 2012(?):314283. doi:
10.1100/2012/314283. [PMID: 22654591] - B Sjouke, D M Kusters, J J P Kastelein, G K Hovingh. Familial hypercholesterolemia: present and future management.
Current cardiology reports.
2011 Dec; 13(6):527-36. doi:
10.1007/s11886-011-0219-9. [PMID: 21938413] - Iordanis Mourouzis, Francesca Forini, Constantinos Pantos, Giorgio Iervasi. Thyroid hormone and cardiac disease: from basic concepts to clinical application.
Journal of thyroid research.
2011; 2011(?):958626. doi:
10.4061/2011/958626. [PMID: 21765997] - Adie Viljoen, Anthony S Wierzbicki. Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.
Drug, healthcare and patient safety.
2010; 2(?):61-71. doi:
10.2147/dhps.s7302. [PMID: 21701618] - Beatrice Hamon, Patrick Hamon, Michel Bovier-Lapierre, Michel Pugeat, Frederique Savagner, Patrice Rodien, Jacques Orgiazzi. A child with resistance to thyroid hormone without thyroid hormone receptor gene mutation: a 20-year follow-up.
Thyroid : official journal of the American Thyroid Association.
2008 Jan; 18(1):35-44. doi:
10.1089/thy.2007.0079. [PMID: 18302516] - Samita Kundu, Mitali Pramanik, Sumedha Roy, Jhuma De, Angshuman Biswas, Arun K Ray. Maintenance of brain thyroid hormone level during peripheral hypothyroid condition in adult rat.
Life sciences.
2006 Sep; 79(15):1450-5. doi:
10.1016/j.lfs.2006.04.006. [PMID: 16698041] - Anna M Giudetti, Monica Leo, Math J H Geelen, Gabriele V Gnoni. Short-term stimulation of lipogenesis by 3,5-L-diiodothyronine in cultured rat hepatocytes.
Endocrinology.
2005 Sep; 146(9):3959-66. doi:
10.1210/en.2005-0345. [PMID: 15932927] - Edith C H Friesema, Sumita Ganguly, Amal Abdalla, Jocelyn E Manning Fox, Andrew P Halestrap, Theo J Visser. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter.
The Journal of biological chemistry.
2003 Oct; 278(41):40128-35. doi:
10.1074/jbc.m300909200. [PMID: 12871948] - Hiroshi Uchino, Yoshikatsu Kanai, Do Kyung Kim, Michael F Wempe, Arthit Chairoungdua, Emiko Morimoto, M W Anders, Hitoshi Endou. Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition.
Molecular pharmacology.
2002 Apr; 61(4):729-37. doi:
10.1124/mol.61.4.729. [PMID: 11901210] - G Sarkissian, A Dace, A Mesmacque, H Bony-Trifunovic, C Malezet-Desmoulins, J Torresani, A Margotat. A novel resistance to thyroid hormone associated with a new mutation (T329N) in the thyroid hormone receptor beta gene.
Thyroid : official journal of the American Thyroid Association.
1999 Feb; 9(2):165-71. doi:
10.1089/thy.1999.9.165. [PMID: 10090317] - C Bommer, E Werle, I Walter-Sack, C Keller, F Gehlen, C Wanner, M Nauck, W März, H Wieland, J Bommer. D-thyroxine reduces lipoprotein(a) serum concentration in dialysis patients.
Journal of the American Society of Nephrology : JASN.
1998 Jan; 9(1):90-6. doi:
10.1681/asn.v9190. [PMID: 9440092] - N Yokoyama, G N Walker, A J Main, J L Stanton, M M Morrissey, C Boehm, A Engle, A D Neubert, J M Wasvary, Z F Stephan. Synthesis and structure-activity relationships of oxamic acid and acetic acid derivatives related to L-thyronine.
Journal of medicinal chemistry.
1995 Feb; 38(4):695-707. doi:
10.1021/jm00004a015. [PMID: 7861417] - I D Schwartz, B B Bercu. Dextrothyroxine in the treatment of generalized thyroid hormone resistance in a boy homozygous for a defect in the T3 receptor.
Thyroid : official journal of the American Thyroid Association.
1992; 2(1):15-9. doi:
10.1089/thy.1992.2.15. [PMID: 1525565] - F Dorey, G Strauch, J P Gayno. Thyrotoxicosis due to pituitary resistance to thyroid hormones. Successful control with D thyroxine: a study in three patients.
Clinical endocrinology.
1990 Feb; 32(2):221-8. doi:
10.1111/j.1365-2265.1990.tb00858.x. [PMID: 2189602] - D R Illingworth, S Bacon. Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs.
Arteriosclerosis (Dallas, Tex.).
1989 Jan; 9(1 Suppl):I121-34. doi:
. [PMID: 2492189] - K S Ritter. Steinernema feltiae (= Neoaplectana carpocapsae): effect of sterols and hypolipidemic agents on development.
Experimental parasitology.
1988 Dec; 67(2):257-67. doi:
10.1016/0014-4894(88)90073-2. [PMID: 3191959] - P Hamon, M Bovier-Lapierre, M Robert, D Peynaud, M Pugeat, J Orgiazzi. Hyperthyroidism due to selective pituitary resistance to thyroid hormones in a 15-month-old boy: efficacy of D-thyroxine therapy.
The Journal of clinical endocrinology and metabolism.
1988 Nov; 67(5):1089-93. doi:
10.1210/jcem-67-5-1089. [PMID: 3182960] - B Busnardo, N Simioni, M E Girelli, T Rampazzo, A Pagnan, G Zanetti, S Dotto, N Ciuccio. Acute and chronic effects of dextro-thyroxine on pituitary thyroid axis and on reverse triiodothyronine production in euthyroid subjects.
Journal of endocrinological investigation.
1987 Feb; 10(1):73-7. doi:
10.1007/bf03347158. [PMID: 3598077] - P L Canner, K G Berge, N K Wenger, J Stamler, L Friedman, R J Prineas, W Friedewald. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin.
Journal of the American College of Cardiology.
1986 Dec; 8(6):1245-55. doi:
10.1016/s0735-1097(86)80293-5. [PMID: 3782631] - R S Perry. Contemporary recommendations for evaluating and treating hyperlipidemia.
Clinical pharmacy.
1986 Feb; 5(2):113-27. doi:
NULL. [PMID: 3514084] - ". Lipid-lowering drugs.
The Medical letter on drugs and therapeutics.
1985 Aug; 27(695):74-6. doi:
". [PMID: 3860714] - F Parker. Xanthomas and hyperlipidemias.
Journal of the American Academy of Dermatology.
1985 Jul; 13(1):1-30. doi:
10.1016/s0190-9622(85)70139-9. [PMID: 4031142] - I D Hay, C A Gorman, K D Burman, N S Jiang. Stereospecific determination and in vivo monodeiodination of thyroxine enantiomers in euthyroid man.
Metabolism: clinical and experimental.
1985 Mar; 34(3):266-71. doi:
10.1016/0026-0495(85)90011-3. [PMID: 3974453] - W F Young, C A Gorman, N S Jiang, D Machacek, I D Hay. L-thyroxine contamination of pharmaceutical D-thyroxine: probable cause of therapeutic effect.
Clinical pharmacology and therapeutics.
1984 Dec; 36(6):781-7. doi:
10.1038/clpt.1984.257. [PMID: 6499357] - S Yosha, C Longcope, L E Braverman. The effect of D- and L-thyroxine on sex hormone-binding globulin in rabbits.
Endocrinology.
1984 Oct; 115(4):1446-50. doi:
10.1210/endo-115-4-1446. [PMID: 6541121] - J P Bantle, D B Hunninghake, I D Frantz, K Kuba, C N Mariash, J H Oppenheimer. Comparison of effectiveness of thyrotropin-suppressive doses of D- and L-thyroxine in treatment of hypercholesterolemia.
The American journal of medicine.
1984 Sep; 77(3):475-81. doi:
10.1016/0002-9343(84)90107-4. [PMID: 6475988] - W V Brown, I J Goldberg, H N Ginsberg. Treatment of common lipoprotein disorders.
Progress in cardiovascular diseases.
1984 Jul; 27(1):1-20. doi:
10.1016/0033-0620(84)90017-3. [PMID: 6330792] - A Pagnan, B Busnardo, G Zanetti, N Simioni, M Braggion, L Ziron, M E Girelli. Effects of dextro-thyroxine, a preparation almost free of levo-thyroxine, on thyroid function, serum lipids and apolipoprotein A-I in 'double pre-beta lipoproteinemia'.
Atherosclerosis.
1984 Feb; 50(2):191-202. doi:
10.1016/0021-9150(84)90022-4. [PMID: 6424687] - J H Hankins, C M Heise, R J Cowan. Iatrogenic hyperthyroidism secondary to dextrothyroxine administration.
Clinical nuclear medicine.
1984 Jan; 9(1):17-9. doi:
10.1097/00003072-198401000-00007. [PMID: 6697613] - D B Hunninghake. Pharmacologic therapy for the hyperlipidemic patient.
The American journal of medicine.
1983 May; 74(5A):19-22. doi:
10.1016/s0002-9343(18)30278-x. [PMID: 6846378] - D Sailer, S Kolb. [Treatment of coronary heart disease with diet and lipid-reducing agents].
Fortschritte der Medizin.
1982 Nov; 100(43):2005-10. doi:
". [PMID: 7152437] - K H Vogelberg, T Koschinsky, H Hein, F A Gries. Effect of neomycin sulphate alone and in combination with D-thyroxine on serum lipoproteins in hypercholesterolaemic subjects.
European journal of clinical pharmacology.
1982; 22(1):33-8. doi:
10.1007/bf00606422. [PMID: 7094972] - G Leb, E P Lankmayr, R Goebel, H Pristautz, F Nachtmann, G Knapp. Stereospecific determination of D-thyroxin and L-thyroxin in serum.
Klinische Wochenschrift.
1981 Aug; 59(15):861-3. doi:
10.1007/bf01721057. [PMID: 6790815] - S R Srinivasan, D Patton, B Radhakrishnamurthy, T A Foster, M R Malinow, P McLaughlin, G S Berenson. Lipid changes in atherosclerotic aortas of Macaca fascicularis after various regression regimens.
Atherosclerosis.
1980 Dec; 37(4):591-601. doi:
10.1016/0021-9150(80)90066-0. [PMID: 7459002] - L D Brun, C Gagné, P Coulombe, P J Lupien, J H Dussault, S Moorjani. Effects of dextrothyroxine on the pituitary-thyroid axis in hypercholesterolemic children and goitrous adults.
The Journal of clinical endocrinology and metabolism.
1980 Dec; 51(6):1306-10. doi:
10.1210/jcem-51-6-1306. [PMID: 6777394] - P Schwandt, P Weisweiler. The effect of D-thyroxine on lipoprotein lipids and apolipoproteins in primary type IIa hyperlipoproteinemia.
Atherosclerosis.
1980 Mar; 35(3):301-6. doi:
10.1016/0021-9150(80)90128-8. [PMID: 6987993] - H Pristautz, G Leb, J Raber, R Goebel, R Steinberger, J Borkenstein. [Influence of a highly purified D-thyroxine medication on thyroid iodine uptake and in vitro tests of thyroid function (author's transl)].
MMW, Munchener medizinische Wochenschrift.
1980 Feb; 122(6):199-202. doi:
NULL. [PMID: 6767955] - V Schreiber, T Pribyl, J Jahodová. Reactions of hypothalamic ascorbic acid, serum ceruloplasmin and the adenohypophysis to oestradiol: inhibition by L-thyroxine.
Physiologia Bohemoslovaca.
1980; 29(1):11-20. doi:
. [PMID: 6444734] - K H Vogelberg. [Lipid-lowering drugs. Therapeutics and adverse effects].
Medizinische Klinik.
1979 Aug; 74(32-33):1171-8. doi:
". [PMID: 224293] - R Beckmann. [Expeimental studies in animals on a new lipid lowering compound: etiroxate hydrochloride (author's transl)].
Arzneimittel-Forschung.
1979; 29(3):499-508. doi:
NULL. [PMID: 582735] - L R Garibaldi, C Borrone, I de Martini, E Battistini. Dextrothyroxine treatment of phosphorylase-kinase deficiency glycogenosis in four boys.
Helvetica paediatrica acta.
1978 Nov; 33(4-5):435-41. doi:
NULL. [PMID: 280544] - M R Malinow, P McLaughlin, W P McNulty, H K Naito, L A Lewis. Treatment of established atherosclerosis during cholesterol feeding in monkeys.
Atherosclerosis.
1978 Oct; 31(2):185-93. doi:
10.1016/0021-9150(78)90164-8. [PMID: 103561] - J Schneider, R Schubotz, E v Manteuffel, H Kaffarnik. [Drug treatment of hypercholesterolemia. Experience with a combination of dextrothyroxine and betapyridylcarbinol (author's transel)].
Medizinische Klinik.
1978 Jun; 73(23):874-7. doi:
". [PMID: 661731] - G Klose, R Mordasini, G Middelhoff, J Augustin, H Greten. [Drug treatment of primary hyperlipoproteinemia (author's transl)].
Klinische Wochenschrift.
1978 Feb; 56(3):99-110. doi:
10.1007/bf01478565. [PMID: 628199] - K Sterling, P O Milch, M A Brenner, J H Lazarus. Thyroid hormone action: the mitochondrial pathway.
Science (New York, N.Y.).
1977 Sep; 197(4307):996-9. doi:
10.1126/science.196334. [PMID: 196334] - N O Borhani. Primary prevention of coronary heart disease: a critique.
The American journal of cardiology.
1977 Aug; 40(2):251-9. doi:
10.1016/0002-9149(77)90016-9. [PMID: 195453] - R D Hempel, G Müller, U Burchardt. [D-thyroxin in the therapy of type IIa and IIb hyperlipoproteinemias].
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete.
1977 Jun; 32(11):suppl 175-6. doi:
NULL. [PMID: 201111] - K H Gless, P Oster, M Hüfner. Influence of D-thyroxine on plasma thyroid hormone levels and TSH secretion.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1977 Jan; 9(1):69-73. doi:
10.1055/s-0028-1093587. [PMID: 403117] - R I Levy. The effect of hypolipidemic drugs on plasma lipoproteins.
Annual review of pharmacology and toxicology.
1977; 17(?):499-510. doi:
10.1146/annurev.pa.17.040177.002435. [PMID: 326171] - I D Frantz. Results of treatment of hyperlipidemias: long-term compliance and effect of lipid metabolism.
Advances in experimental medicine and biology.
1977; 82(?):649-55. doi:
10.1007/978-1-4613-4220-5_136. [PMID: 920422] - D Yeshurun, A M Gotto. Drug treatment of hyperlipidemia.
The American journal of medicine.
1976 Mar; 60(3):379-96. doi:
10.1016/0002-9343(76)90755-5. [PMID: 1258886] - R Nandan, J D Fisher, E P Towery, D R Brown, E Ganote, R B Jennings. Effects of dextrothyroxine on hyperlipidemia and experimental atherosclerosis in beagle dogs.
Atherosclerosis.
1975 Sep; 22(2):299-311. doi:
10.1016/0021-9150(75)90011-8. [PMID: 172095] - G Schettler. [Serum lipid-lowering drugs following myocardial infarction].
Deutsche medizinische Wochenschrift (1946).
1975 Aug; 100(31):1611-2. doi:
NULL. [PMID: 168052] - P F Hansen. The efficacy of lipid lowering drugs alone and in combination.
Postgraduate medical journal.
1975; 51(8):63-5. doi:
". [PMID: 768949] - E N Wardle, W Schardt, P R Uldall, A Brown, D Jonfiah, A Moore, R Park, E Wood. Study of the lipid-lowering action of choloxin and nilevar in patients with chronic renal failure.
Postgraduate medical journal.
1974 Dec; 50(590):737-40. doi:
10.1136/pgmj.50.590.737. [PMID: 4469041] - K M Detre, L Shaw. Long-term changes of serum cholesterol with cholesterol-altering drugs in patients with coronary heart disease. Veterans Administration Drug-Lipid Cooperative Study.
Circulation.
1974 Nov; 50(5):998-1005. doi:
10.1161/01.cir.50.5.998. [PMID: 4609636] - A Notarbartolo, G Di Fede, G Cupidi, G B Rini. [Changes induced by D-thyroxine treatment in blood lipid indices in arteriosclerotic subjects].
Bollettino della Societa italiana di biologia sperimentale.
1974 Aug; 50(13):979-83. doi:
". [PMID: 4463989] - D Berkowitz. Management of the hyperlipidemic patient.
The Medical clinics of North America.
1973 Jul; 57(4):881-92. doi:
10.1016/s0025-7125(16)32239-8. [PMID: 4576152] - A Bernstein, F Simon, T H Schmitz, W L Warner. The effect of sodium dextrothyroxine on serum cholesterol and mortality rates in cardiac patients.
Angiology.
1973 Apr; 24(4):205-11. doi:
10.1177/000331977302400402. [PMID: 4699516] - D M Krikler. Therapy of lipid disorders.
Journal of clinical pathology. Supplement (Association of Clinical Pathologists).
1973; 5(?):72-7. doi:
10.1136/jcp.s1-5.1.72. [PMID: 4582173] - ". Lipid lowering agents.
British medical journal.
1972 Jun; 2(5814):642-3. doi:
". [PMID: 5031693] - R Calay, P Kocheleff, G Jonniaux, L Sohet, P A Bastenie. Dextrothyroxine therapy for the disordered lipid metabolism of preclinical hypothyroidism.
Lancet (London, England).
1971 Jan; 1(7692):205-6. doi:
10.1016/s0140-6736(71)90948-2. [PMID: 4099873] - L D Bechtol, W L Warner. Dextrothyroxine for lowering serum cholesterol. Analysis of data on 6066 patients.
Angiology.
1969 Nov; 20(10):565-79. doi:
10.1177/000331976902001001. [PMID: 5347944] - A Arteaga, H Cisternas, M C Torres, M E Alliende. [Effects of diet changes and use of dextrothyroxine and chlorphenisate on serum lipids].
Revista medica de Chile.
1969 May; 97(5):285-90. doi:
NULL. [PMID: 5386042] - W E Connor. Measures to reduce the serum lipid levels in coronary heart disease.
The Medical clinics of North America.
1968 Sep; 52(5):1249-60. doi:
NULL. [PMID: 4876837] - R L Searcy, D A Hungerford, E M Low. Effects of dextrothyroxine on serum lipoprotein and cholesterol levels.
Current therapeutic research, clinical and experimental.
1968 Apr; 10(4):177-86. doi:
NULL. [PMID: 4967872] - H Schindler. [The metabolic effect of dextrothyorxine in hypothyreoses].
Wiener medizinische Wochenschrift (1946).
1968 Feb; 118(5):98-100. doi:
NULL. [PMID: 4174089] - D Brox, O Selvaag. The effect of erythritol-tetra-nicotinate on serum-cholesterol levels in man.
Acta medica Scandinavica.
1967 Oct; 182(4):437-44. doi:
10.1111/j.0954-6820.1967.tb10868.x. [PMID: 6054827] - M M Best, C H Duncan. Effects of clofibrate and dextrothyroxine singly and in combination on serum lipids.
Archives of internal medicine.
1966 Aug; 118(2):97-102. doi:
NULL. [PMID: 5329616] - G Salvi, R I Portioli, A C Plancher, L Piacentini. [The plasma transport of levo- and dextrothyroxine studied by means of dialysis equilibrium].
Folia endocrinologica.
1965 Aug; 18(4):434-41. doi:
NULL. [PMID: 5898918] - A NAVA-RIVERA, L BERNAL-DIAZ, M AVENDANO-OLVERA. [RELATIONS BETWEEN THE METABOLISM OF CHOLESTEROL AND CARBOHYDRATES. II. ANTAGONISM OF NICOTINIC ACID AND D- THYROXINE IN EUTHYROID RATS].
Boletin del Instituto de Estudios Medicos y Biologicos, Universidad Nacional Autonoma de Mexico.
1964 Dec; 22(?):415-21. doi:
". [PMID: 14247452] - W J ZINN, L A SCHLEISSNER. THE EFFECTS OF DEXTROTHYROXINE IN DIABETES.
California medicine.
1964 Oct; 101(?):240-5. doi:
NULL. [PMID: 14204552] - A NAVARIVERA, L BERNALDIAZ, M AVENDANOOLVERA. [RELATION BETWEEN CHOLESTEROL AND CARBOHYDRATE METABOLISM. I. NICOTINIC ACID AND D-THYROXINE ANTAGONISM WITH INSULIN IN HYPOTHYROID RATS].
Boletin del Instituto de Estudios Medicos y Biologicos, Universidad Nacional Autonoma de Mexico.
1964 Aug; 22(?):323-30. doi:
". [PMID: 14200269] - A LEPP, S R WAGLE, L OLINER. EFFECTS OF L- AND D-THYROXINE ON CHOLESTEROL SYNTHESIS AND TURNOVER IN THE CHICK.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1964 Feb; 115(?):517-21. doi:
10.3181/00379727-115-28956. [PMID: 14121653] - C H DUNCAN, M M BEST, R J LUBBE. EFFECTS OF L- AND D-THYROXINE AND OF THYROIDECTOMY ON TISSUE WEIGHTS AND CHOLESTEROL CONTENT OF THE RAT.
Metabolism: clinical and experimental.
1964 Jan; 13(?):1-7. doi:
10.1016/s0026-0495(64)80002-0. [PMID: 14105455] - G VERDONK. THE INFLUENCE OF NUTRITIONAL AND PHARMACOLOGICAL FACTORS ON THE BLOOD LIPID PATTERN IN ATHEROSCLEROTIC DISEASE AND IN THE TREATMENT OF PEPTIC ULCER.
Bibliotheca nutritio et dieta.
1964; 6(?):106-38. doi:
10.1159/000385031. [PMID: 14247430] - E B FELDMAN, A C CARTER. REDUCTION OF SERUM TRIGLYCERIDES IN PATIENTS TREATED WITH SODIUM D-THYROXINE.
Metabolism: clinical and experimental.
1963 Dec; 12(?):1132-40. doi:
NULL. [PMID: 14100284] - E V FLOCK, C DAVID, G A HALLENBECK, C A OWEN. METABOLISM OF D-THYROXINE.
Endocrinology.
1963 Dec; 73(?):764-74. doi:
10.1210/endo-73-6-764. [PMID: 14089635] - R L ROMERO, R RODRIGUEZ, F FERRARA, L MALJAR, J CACCIATORE, H V VELARDE. [INFLUENCE OF SODIUM DEXTROTHYROXIN IN THE HORMONAL IMBALANCE OF ATHEROSCLEROSIS].
Prensa medica argentina.
1963 Feb; 50(?):550-1. doi:
". [PMID: 14059107] - R MORGAN, W J GRACE. Effect of dextrothyroxine on serum cholesterol.
Current therapeutic research, clinical and experimental.
1962 Jun; 4(?):297-300. doi:
NULL. [PMID: 14475971] - C DUFAULT, G TREMBLAY, W NOWACZYNSKI, J GENEST. [The effect of dextrothyroxin and androsterone on serum cholesterol and the coagulation factors in atherosclerotics].
Medecine et hygiene.
1962 Apr; 20(?):307-11. doi:
NULL. [PMID: 13888220] - N G SCHNEEBERG, E HERMAN, H MENDUKE, N K ALTSCHULER. Reduction of serum cholesterol by sodium dextrothyroxine in euthyroid subjects.
Annals of internal medicine.
1962 Feb; 56(?):265-75. doi:
10.7326/0003-4819-56-2-265. [PMID: 13908890] - E M GOYETTE, A SAAD. The use of triparanol and sodium dextrothyroxine to lower serum cholesterol.
Angiology.
1962 Feb; 13(?):88-93. doi:
NULL. [PMID: 13900898] - W R OWEN, W B NEELY, J C OWENS. Effect of sodium dextrothyroxine on serum cholesterol in man.
JAMA.
1961 Dec; 178(?):1036-8. doi:
10.1001/jama.1961.73040490026015b. [PMID: 14482904] - R L SEARCY, J S CARLUCCI, V P CARROLL, G S GOUGH, L M BERGQUIST. Effect of d-thyroxine on serum lactescence.
Lancet (London, England).
1961 Aug; 2(7200):492-3. doi:
10.1016/s0140-6736(61)92466-7. [PMID: 13749497] - R GREENE, J F PEARCE, D F RIDEOUT. Effect of D-thyroxine on serum cholesterol.
British medical journal.
1961 Jun; 1(5239):1572-4. doi:
10.1136/bmj.1.5239.1572. [PMID: 13708306] - F C LARSON, K TOMITA, E C ALBRIGHT. In vitro metabolism of D-thyroxine.
Endocrinology.
1959 Aug; 65(2):336-9. doi:
10.1210/endo-65-2-336. [PMID: 13672158]
