Trilobatin (BioDeep_00000026542)
Main id: BioDeep_00000230226
human metabolite PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C21H24O10 (436.13694039999996)
中文名称: 三叶苷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)OC3C(C(C(C(O3)CO)O)O)O)O)O
InChI: InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2
描述信息
Trilobatin is found in pomes. Trilobatin is isolated from apple leaves.
Isolated from apple leaves. Trilobatin is found in pomes.
Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].
Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd[1], Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope[2]. Neuroprotective effects[1]. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells[3].
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- PubChem: 13188898
- HMDB: HMDB0037505
- KNApSAcK: C00007991
- foodb: FDB016580
- chemspider: 24846091
- CAS: 4192-90-9
- PMhub: MS000227562
- medchemexpress: HY-N4100
- LOTUS: LTS0003865
- LOTUS: LTS0037546
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
62 个相关的物种来源信息
- 25674 - Balanophora: LTS0003865
- 25674 - Balanophora: LTS0037546
- 447008 - Balanophora harlandii: 10.1002/HLCA.200900036
- 447008 - Balanophora harlandii: LTS0003865
- 447008 - Balanophora harlandii: LTS0037546
- 1128104 - Balanophora tobiracola: 10.1016/J.PHYTOCHEM.2004.10.018
- 1128104 - Balanophora tobiracola: LTS0003865
- 1128104 - Balanophora tobiracola: LTS0037546
- 25673 - Balanophoraceae: LTS0003865
- 25673 - Balanophoraceae: LTS0037546
- 193306 - Eriolobus: LTS0003865
- 193306 - Eriolobus: LTS0037546
- 193307 - Eriolobus trilobatus: 10.1039/JR9610004133
- 193307 - Eriolobus trilobatus: LTS0003865
- 193307 - Eriolobus trilobatus: LTS0037546
- 2759 - Eukaryota: LTS0003865
- 2759 - Eukaryota: LTS0037546
- 3503 - Fagaceae: LTS0003865
- 3503 - Fagaceae: LTS0037546
- 292393 - Gentiana scabra var. buesgeri: -
- 9606 - Homo sapiens: -
- 82113 - Lithocarpus: LTS0003865
- 82113 - Lithocarpus: LTS0037546
- 425828 - Lithocarpus litseifolius: 10.1080/00021369.1982.10865357
- 425828 - Lithocarpus litseifolius: LTS0003865
- 425828 - Lithocarpus litseifolius: LTS0037546
- 167412 - Lithocarpus pachyphyllus: 10.1515/ZNC-2003-9-1029
- 167412 - Lithocarpus pachyphyllus: LTS0037546
- 2518020 - Lithocarpus polystachyus: 10.1080/00021369.1982.10865357
- 2518020 - Lithocarpus polystachyus: 10.3390/12030552
- 2518020 - Lithocarpus polystachyus: LTS0003865
- 2518020 - Lithocarpus polystachyus: LTS0037546
- 3398 - Magnoliopsida: LTS0003865
- 3398 - Magnoliopsida: LTS0037546
- 3749 - Malus: LTS0003865
- 3749 - Malus: LTS0037546
- 106570 - Malus trilobata: 10.1039/JR9610004133
- 106570 - Malus trilobata: LTS0003865
- 106570 - Malus trilobata: LTS0037546
- 33090 - Plants: -
- 3745 - Rosaceae: LTS0003865
- 3745 - Rosaceae: LTS0037546
- 35493 - Streptophyta: LTS0003865
- 35493 - Streptophyta: LTS0037546
- 239704 - Symplocos lancifolia: 10.1055/S-2008-1075008
- 58023 - Tracheophyta: LTS0003865
- 58023 - Tracheophyta: LTS0037546
- 33090 - Viridiplantae: LTS0003865
- 33090 - Viridiplantae: LTS0037546
- 3602 - Vitaceae: LTS0003865
- 3602 - Vitaceae: LTS0037546
- 3603 - Vitis: LTS0003865
- 3603 - Vitis: LTS0037546
- 228411 - Vitis piasezkii: 10.1271/BBB1961.47.2403
- 228411 - Vitis piasezkii: LTS0003865
- 228411 - Vitis piasezkii: LTS0037546
- 694579 - Vitis saccharifera: 10.1271/BBB1961.47.2403
- 694579 - Vitis saccharifera: LTS0003865
- 694579 - Vitis saccharifera: LTS0037546
- 29760 - Vitis vinifera: 10.1186/S12870-016-0760-1
- 29760 - Vitis vinifera: 10.3389/FPLS.2017.01124
- 29760 - Vitis vinifera: LTS0037546
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Thomas Dugé de Bernonville, Sylvain Guyot, Jean-Pierre Paulin, Matthieu Gaucher, Laurent Loufrani, Daniel Henrion, Séverine Derbré, David Guilet, Pascal Richomme, James F Dat, Marie-Noëlle Brisset. Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction.
Phytochemistry.
2010 Mar; 71(4):443-52. doi:
10.1016/j.phytochem.2009.11.004
. [PMID: 20022617] - Wei-Min Yang, Ji-Kai Liu, Xiang-Dong Qin, Wan-Lin Wu, Zhi-He Chen. Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2004 Jul; 59(7-8):481-4. doi:
10.1515/znc-2004-7-805
. [PMID: 15813365] - Xiang-Dong Qin, Ji-Kai Liu. A new sweet dihydrochalcone-glucoside from leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae).
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2003 Sep; 58(9-10):759-61. doi:
10.1515/znc-2003-9-1029
. [PMID: 14577645] - Jochen M Scher, Josef Zapp, Hans Becker. Lignan derivatives from the liverwort Bazzania trilobata.
Phytochemistry.
2003 Mar; 62(5):769-77. doi:
10.1016/s0031-9422(02)00626-x
. [PMID: 12620330]