Physalin A (BioDeep_00000021396)

human metabolite PANOMIX_OTCML-2023 Endogenous natural product

代谢物信息卡片

5,7,18-trihydroxy-1,14,21-trimethyl-25-methylidene-4,20,23-trioxaheptacyclo[20.3.1.1²,⁵.0³,¹⁸.0³,²¹.0⁶,¹⁵.0⁹,¹⁴]heptacosa-8,11-diene-13,19,24,27-tetrone

化学式: C28H30O10 (526.183888)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1C(=O)OC2CC1(C)C1C(=O)C3(O)OC14C(O)(CCC1C3C(O)C=C3CC=CC(=O)C31C)C(=O)OC24C
InChI: InChI=1S/C28H30O10/c1-12-21(32)36-17-11-23(12,2)19-20(31)27(35)18-14(24(3)13(10-15(18)29)6-5-7-16(24)30)8-9-26(34)22(33)37-25(17,4)28(19,26)38-27/h5,7,10,14-15,17-19,29,34-35H,1,6,8-9,11H2,2-4H3

描述信息

Physalin A is found in fruits. Physalin A is from Physalis alkekengi (winter cherry).

同义名列表

6 个代谢物同义名

5,7,18-trihydroxy-1,14,21-trimethyl-25-methylidene-4,20,23-trioxaheptacyclo[20.3.1.1²,⁵.0³,¹⁸.0³,²¹.0⁶,¹⁵.0⁹,¹⁴]heptacosa-8,11-diene-13,19,24,27-tetrone; 20-Hydroxy-3-taraxastanone; Y-Taraxastanonol; g-Taraxastanonol; Γ-taraxastanonol; Physalin A

数据库引用编号

5 个数据库交叉引用编号

PubChem: 12314218
HMDB: HMDB0033773
CAS: 23027-91-0
PMhub: MS000062452
LOTUS: LTS0095002

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

33120 - Alkekengi officinarum: 10.1021/NP700713R
2759 - Eukaryota: LTS0095002
9606 - Homo sapiens: -
3398 - Magnoliopsida: LTS0095002
24663 - Physalis: LTS0095002
304149 - Physalis lagascae: 10.1016/0031-9422(93)80040-Y
304149 - Physalis lagascae: 10.1016/J.STEROIDS.2011.11.016
304149 - Physalis lagascae: 10.1016/S0031-9422(00)82495-4
304149 - Physalis lagascae: 10.1021/NP700713R
304149 - Physalis lagascae: LTS0095002
304153 - Physalis minima: 10.1016/0031-9422(93)80040-Y
304153 - Physalis minima: 10.1016/J.STEROIDS.2011.11.016
304153 - Physalis minima: 10.1016/S0031-9422(00)82495-4
304153 - Physalis minima: 10.1021/NP700713R
304153 - Physalis minima: LTS0095002
4070 - Solanaceae: LTS0095002
35493 - Streptophyta: LTS0095002
58023 - Tracheophyta: LTS0095002
33090 - Viridiplantae: LTS0095002

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Yunliang Zheng, Meihua Lin, Xingjiang Hu, You Zhai, Qiao Zhang, Yan Lou, Jianzhong ShenTu, Lihua Wu. Simultaneous pharmacokinetics and stability studies of physalins in rat plasma and intestinal bacteria culture media using liquid chromatography with mass spectrometry. Journal of separation science. 2018 Apr; 41(8):1781-1790. doi: 10.1002/jssc.201701089. [PMID: 29331063]
Hongxia Liu, Kai Wang, Guiyang Xia, Kun Wang, Liwei Chai, Paul Owusu Donkor, Liqin Ding, Feng Qiu. Two sulfonate metabolites of physalin A in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Jan; 48(1):11-17. doi: 10.1080/00498254.2016.1271961. [PMID: 28001472]
Xinchi Feng, Hongxia Liu, Liwei Chai, Liqin Ding, Guixiang Pan, Feng Qiu. Metabolic profiles of physalin A in rats using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Mar; 1046(?):102-109. doi: 10.1016/j.jchromb.2017.01.037. [PMID: 28157662]