Ganoderic acid B (BioDeep_00000020386)

Main id: BioDeep_00000230384

 

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


6-(3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid

化学式: C30H44O7 (516.3086874)
中文名称: 灵芝酸B
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@@H](C([C@H]2[C@](C1)(C1=C([C@H](C2)O)[C@]2([C@@](CC1=O)(C)[C@H](CC2=O)[C@H](C)CC(=O)C[C@H](C(=O)O)C)C)C)(C)C)O
InChI: InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21-22,32,34H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,22+,28+,29-,30+/m1/s1

描述信息

Ganoderic acid B is found in mushrooms. Ganoderic acid B is a constituent of Ganoderma lucidum (reishi)
Constituent of Ganoderma lucidum (reishi). Ganoderic acid B is found in mushrooms.
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease[1][2][3].
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease[1][2][3].

同义名列表

5 个代谢物同义名

6-(3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid; 6-{5,9-dihydroxy-2,6,6,11,15-pentamethyl-12,17-dioxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-14-yl}-2-methyl-4-oxoheptanoic acid; 6-{5,9-dihydroxy-2,6,6,11,15-pentamethyl-12,17-dioxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-14-yl}-2-methyl-4-oxoheptanoate; Ganoderic acid B; Ganoderate b



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Changda Liu, Mingzhuo Cao, Nan Yang, Jessica Reid-Adam, Jody Tversky, Jixun Zhan, Xiu-Min Li. Time-dependent dual beneficial modulation of interferon-γ, interleukin 5, and Treg cytokines in asthma patient peripheral blood mononuclear cells by ganoderic acid B. Phytotherapy research : PTR. 2022 Mar; 36(3):1231-1240. doi: 10.1002/ptr.7266. [PMID: 35112740]
  • M Ramakrishna, D Rajesh Babu, S S Veena, Meera Pandey, Nageswara Rao. A Validated Reverse-Phase HPLC Method for Quantitative Determination of Ganoderic Acids A and B in Cultivated Strains of Ganoderma spp. (Agaricomycetes) Indigenous to India. International journal of medicinal mushrooms. 2017; 19(5):457-465. doi: 10.1615/intjmedmushrooms.v19.i5.70. [PMID: 28845774]
  • Xiaoyu Guo, Xuan Shen, Jie Long, Jian Han, Qingming Che. Structural identification of the metabolites of ganoderic acid B from Ganoderma lucidum in rats based on liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry. Biomedical chromatography : BMC. 2013 Sep; 27(9):1177-87. doi: 10.1002/bmc.2924. [PMID: 23723086]
  • Xiao-Qi Zhang, Fanny C F Ip, Dong-Mei Zhang, Li-Xin Chen, Wei Zhang, Yao-Lan Li, Nancy Y Ip, Wen-Cai Ye. Triterpenoids with neurotrophic activity from Ganoderma lucidum. Natural product research. 2011 Oct; 25(17):1607-13. doi: 10.1080/14786419.2010.496367. [PMID: 21671206]
  • P Ding, Y Zhen, X Lai, H Xu. [Effects of places and stages on the contents of ganoderic acid B from Ganoderma lucidum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 1999 Jun; 22(6):271-2. doi: ". [PMID: 12575063]