3'-O-methyl-(-)-epicatechin (BioDeep_00000019709)

Main id: BioDeep_00000269868

Secondary id: BioDeep_00000270016, BioDeep_00000871748

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol

化学式: C16H16O6 (304.0946836)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C=CC(=C1)C2C(CC3=C(C=C(C=C3O2)O)O)O)O
InChI: InChI=1S/C16H16O6/c1-21-15-4-8(2-3-11(15)18)16-13(20)7-10-12(19)5-9(17)6-14(10)22-16/h2-6,13,16-20H,7H2,1H3

描述信息

3-O-methyl-(-)-epicatechin is an urinary and gut-derived metabolite of epicatechin.

同义名列表

5 个代谢物同义名

(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 3-O-methyl-(-)-epicatechin; 3-O-Methylepicatechin; Symplocosidin; Arachidoside



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lucas Actis-Goretta, Antoine Lévèques, Francesca Giuffrida, Fedor Romanov-Michailidis, Florian Viton, Denis Barron, Montserrat Duenas-Paton, Susana Gonzalez-Manzano, Celestino Santos-Buelga, Gary Williamson, Fabiola Dionisi. Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans. Free radical biology & medicine. 2012 Aug; 53(4):787-95. doi: 10.1016/j.freeradbiomed.2012.05.023. [PMID: 22664313]
  • Jack W Blount, Mario Ferruzzi, Dan Raftery, Giulio M Pasinetti, Richard A Dixon. Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders. Biochemical and biophysical research communications. 2012 Jan; 417(1):457-61. doi: 10.1016/j.bbrc.2011.11.139. [PMID: 22166210]
  • Cleber A Schmidt, Renato Murillo, Torsten Bruhn, Gerhard Bringmann, Marcia Goettert, Berta Heinzmann, Volker Brecht, Stefan A Laufer, Irmgard Merfort. Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties. Journal of natural products. 2010 Dec; 73(12):2035-41. doi: 10.1021/np100523s. [PMID: 21080642]
  • Swati Kalgaonkar, Hiroshi Nishioka, Heidrun B Gross, Hajime Fujii, Carl L Keen, Robert M Hackman. Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and indices of metabolic syndrome in animal models. Phytotherapy research : PTR. 2010 Aug; 24(8):1223-8. doi: 10.1002/ptr.3137. [PMID: 20309950]
  • Montserrat Dueñas, Susana González-Manzano, Ana González-Paramás, Celestino Santos-Buelga. Antioxidant evaluation of O-methylated metabolites of catechin, epicatechin and quercetin. Journal of pharmaceutical and biomedical analysis. 2010 Jan; 51(2):443-9. doi: 10.1016/j.jpba.2009.04.007. [PMID: 19442472]
  • Liwei Gu, Suzanne E House, Lloyd W Rooney, Ronald L Prior. Sorghum extrusion increases bioavailability of catechins in weanling pigs. Journal of agricultural and food chemistry. 2008 Feb; 56(4):1283-8. doi: 10.1021/jf072742i. [PMID: 18251504]
  • Liwei Gu, Suzanne E House, Lloyd Rooney, Ronald L Prior. Sorghum bran in the diet dose dependently increased the excretion of catechins and microbial-derived phenolic acids in female rats. Journal of agricultural and food chemistry. 2007 Jun; 55(13):5326-34. doi: 10.1021/jf070100p. [PMID: 17536823]
  • Qin Yan Zhu, Derek D Schramm, Heidrun B Gross, Roberta R Holt, Sun H Kim, Tomoko Yamaguchi, Catherine L Kwik-Uribe, Carl L Keen. Influence of cocoa flavanols and procyanidins on free radical-induced human erythrocyte hemolysis. Clinical & developmental immunology. 2005 Mar; 12(1):27-34. doi: 10.1080/17402520512331329514. [PMID: 15712596]
  • Yumiko Nakamura, Yasuhide Tonogai. Metabolism of grape seed polyphenol in the rat. Journal of agricultural and food chemistry. 2003 Nov; 51(24):7215-25. doi: 10.1021/jf030250+. [PMID: 14611196]
  • Manal M Abd El Mohsen, Gunter Kuhnle, Andreas R Rechner, Hagen Schroeter, Sarah Rose, Peter Jenner, Catherine A Rice-Evans. Uptake and metabolism of epicatechin and its access to the brain after oral ingestion. Free radical biology & medicine. 2002 Dec; 33(12):1693-702. doi: 10.1016/s0891-5849(02)01137-1. [PMID: 12488137]
  • H Schroeter, J P Spencer, C Rice-Evans, R J Williams. Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3. The Biochemical journal. 2001 Sep; 358(Pt 3):547-57. doi: 10.1042/0264-6021:3580547. [PMID: 11535118]