Docosapentaenoate (DPA; 22:5n3) (BioDeep_00000018220)

 

Secondary id: BioDeep_00000628823

human metabolite Endogenous blood metabolite Volatile Flavor Compounds


代谢物信息卡片


(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid

化学式: C22H34O2 (330.2558664)
中文名称: 二十二碳五烯酸 (DPA), 4Z,7Z,10Z,13Z,16Z-二十二碳五烯酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.99%

Reviewed

Last reviewed on 2024-09-25.

Cite this Page

Docosapentaenoate (DPA; 22:5n3). BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/docosapentaenoate_(dpa;_22:5n3) (retrieved 2024-11-25) (BioDeep RN: BioDeep_00000018220). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O
InChI: InChI=1S/C22H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16,18-19H,2-5,8,11,14,17,20-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-,19-18-

描述信息

Docosapentaenoic acid is an unsaturated fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans. Docosapentaenoic acid (22n-6) is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Docosapentaenoic acid (22n-6) can be found in blood and urine, as well as in human adipose tissue, fibroblasts, and platelet tissues. Within the cell, docosapentaenoic acid (22n-6) is primarily located in the membrane (predicted from logP). It can also be found in the extracellular space. In humans, docosapentaenoic acid (22n-6) is involved in alpha-linolenic acid and linoleic acid metabolism. Docosapentaenoic acid (22n-6) is found to be associated with thyroid cancer.
fatty acids, Unsaturated

同义名列表

26 个代谢物同义名

(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid; (4Z,7Z,10Z,13Z,16Z)-4,7,10,13,16-Docosapentaenoic acid; Docosa-4,7,10,13,16-pentaenoic acid, (all-Z)-isomer; all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6; (all-Z)-7, 10, 13, 16, 19-Docosapentaenoic acid; all-cis-Docosa-4,7,10,13,16-pentaenoic acid; (all-Z)-4,7,10,13,16-Docosapentaenoic acid; all-cis-Docosa-4,7,10,13,16-pentaenoate; 4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid; (all-Z)-4,7,10,13,16-Docosapentaenoate; Docosapentaenoic acid, (all Z)-isomer; Docosa-4,7,10,13,16-pentaenoic acid; 4Z,7Z,10Z,13Z,16Z-Docosapentaenoate; Docosapentaenoic acid (C22:5 N6); Docosapentaenoic acid (22n-6); FA(22:5(4Z,7Z,10Z,13Z,16Z)); Docosapentaenoate (22N-6); 22:5(4Z,7Z,10Z,13Z,16Z); docosapentaenoic acid; Docosapentaenoate; Osbond acid; FA(22:5n6); DPAn-6; DPA; 4Z,7Z,10Z,13Z,16Z-Docosapentaenoic Acid; (7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(6)

BioCyc(0)

PlantCyc(0)

代谢反应

54 个相关的代谢反应过程信息。

Reactome(53)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Satoshi Hirako, Takahiro Hirabayashi, Junko Shibato, Ai Kimura, Michio Yamashita, Yuzuru Iizuka, Nobuhiro Wada, Naoko Kaibara, Fumiko Takenoya, Seiji Shioda. Docosapentaenoic acid-rich oil lowers plasma glucose and lipids in a mouse model of diabetes and mild obesity. Nutrition research (New York, N.Y.). 2023 Aug; 118(?):128-136. doi: 10.1016/j.nutres.2023.08.004. [PMID: 37660501]
  • Kenta Furutani, Ouyang Chen, Aidan McGinnis, Yuqing Wang, Charles N Serhan, Trond Vidar Hansen, Ru-Rong Ji. Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice. Pain. 2023 06; 164(6):1340-1354. doi: 10.1097/j.pain.0000000000002824. [PMID: 36378290]
  • Kevin C Maki, Harold E Bays, Christie M Ballantyne, James A Underberg, John J P Kastelein, Judith B Johnson, James J Ferguson. A Head-to-Head Comparison of a Free Fatty Acid Formulation of Omega-3 Pentaenoic Acids Versus Icosapent Ethyl in Adults With Hypertriglyceridemia: The ENHANCE-IT Study. Journal of the American Heart Association. 2022 03; 11(6):e024176. doi: 10.1161/jaha.121.024176. [PMID: 35232215]
  • Chang-Yu Wu, Tomoyo Okuda, Akinori Ando, Ayami Hatano, Hiroshi Kikukawa, Jun Ogawa. Isolation and characterization of the ω3-docosapentaenoic acid-producing microorganism Aurantiochytrium sp. T7. Journal of bioscience and bioengineering. 2022 Mar; 133(3):229-234. doi: 10.1016/j.jbiosc.2021.10.011. [PMID: 34893429]
  • Lifang Wang, Hack Sun Choi, Yan Su, Jung-Hyun Ju, Sun-Yeon Heo, Jong-Jae Yi, Back-Rock Oh, Yong-Suk Jang, Jeong-Woo Seo. The docosahexaenoic acid derivatives, diHEP-DPA and TH-DPA, synthesized via recombinant lipoxygenase, ameliorate disturbances in lipid metabolism and liver inflammation in high fat diet-fed mice. Life sciences. 2022 Feb; 291(?):120219. doi: 10.1016/j.lfs.2021.120219. [PMID: 35041834]
  • Srinivas Belide, Pushkar Shrestha, Yoko Kennedy, Antonio Leonforte, Malcolm D Devine, James R Petrie, Surinder P Singh, Xue-Rong Zhou. Engineering docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) in Brassica juncea. Plant biotechnology journal. 2022 01; 20(1):19-21. doi: 10.1111/pbi.13739. [PMID: 34694688]
  • Alicia Leikin-Frenkel, Aya Mohr-Sasson, Matan Anteby, Michal Kandel-Kfir, Ayelet Harari, Roni Rahav, Yehuda Kamari, Aviv Shaish, Dror Harats, Hofit Cohen, Israel Hendler. Blood fatty acid analysis reveals similar n-3 fatty acid composition in non-pregnant and pregnant women and their neonates in an Israeli pilot study. Prostaglandins, leukotrienes, and essential fatty acids. 2021 10; 173(?):102339. doi: 10.1016/j.plefa.2021.102339. [PMID: 34487973]
  • Jeffery L Heileson, Anthony J Anzalone, Aaron F Carbuhn, Andrew T Askow, Jason D Stone, Stephanie M Turner, Lyn M Hillyer, David W L Ma, Joel A Luedke, Andrew R Jagim, Jonathan M Oliver. The effect of omega-3 fatty acids on a biomarker of head trauma in NCAA football athletes: a multi-site, non-randomized study. Journal of the International Society of Sports Nutrition. 2021 Sep; 18(1):65. doi: 10.1186/s12970-021-00461-1. [PMID: 34579748]
  • Devaraj Parasannanavar, Indraja Gaddam, Tulja Bukya, Ahamed Ibrahim S, Suryam Reddy K, Santosh Kumar Banjara, Blessy P Priyanka Salvadi, Naveen Kumar B, Sylvia Fernandez Rao, J J Babu Geddam, Hemalatha Rajkumar. Omega-3 polyunsaturated fatty acid intake and plasma fatty acids of school going Indian children - a cross-sectional study. Prostaglandins, leukotrienes, and essential fatty acids. 2021 07; 170(?):102294. doi: 10.1016/j.plefa.2021.102294. [PMID: 34052598]
  • Michael A Crawford, Walter F Schmidt, C Leigh Broadhurst, Yiqun Wang. Lipids in the origin of intracellular detail and speciation in the Cambrian epoch and the significance of the last double bond of docosahexaenoic acid in cell signaling. Prostaglandins, leukotrienes, and essential fatty acids. 2021 03; 166(?):102230. doi: 10.1016/j.plefa.2020.102230. [PMID: 33588307]
  • Samaneh Ghasemi Fard, David Cameron-Smith, Andrew J Sinclair. n - 3 Docosapentaenoic acid: the iceberg n - 3 fatty acid. Current opinion in clinical nutrition and metabolic care. 2021 03; 24(2):134-138. doi: 10.1097/mco.0000000000000722. [PMID: 33315722]
  • Kei Hamazaki, Yutaka J Matsuoka, Taiki Yamaji, Norie Sawada, Masaru Mimura, Shoko Nozaki, Ryo Shikimoto, Shoichiro Tsugane. Plasma phospholipid n-3 polyunsaturated fatty acids and major depressive disorder in Japanese elderly: the Japan Public Health Center-based Prospective Study. Scientific reports. 2021 02; 11(1):4003. doi: 10.1038/s41598-021-83478-5. [PMID: 33597590]
  • Chen Zhang, Miao-Miao Zhou, Tian-Tian Zhang, Pei-Xu Cong, Jie Xu, Chang-Hu Xue, Teruyoshi Yanagita, Zi-Hao Wei, Yu-Ming Wang. Effects of Dietary Supplementation with EPA-enriched Phosphatidylcholine and Phosphatidylethanolamine on Glycerophospholipid Profile in Cerebral Cortex of SAMP8 Mice fed with High-fat Diet. Journal of oleo science. 2021 Feb; 70(2):275-287. doi: 10.5650/jos.ess20212. [PMID: 33456004]
  • Yongliang Fan, Abdelaziz Adam Idriss Arbab, Huimin Zhang, Yi Yang, Xubin Lu, Ziyin Han, Zhangping Yang. MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (FADS1) in Bovine Mammary Epithelial Cells. Biomolecules. 2021 01; 11(2):. doi: 10.3390/biom11020157. [PMID: 33504005]
  • Xingjun Meng, Bo Zhu, Yan Liu, Lei Fang, Binbin Yin, Yanni Sun, Mengni Ma, Yuli Huang, Yuning Zhu, Yunlong Zhang. Unique Biomarker Characteristics in Gestational Diabetes Mellitus Identified by LC-MS-Based Metabolic Profiling. Journal of diabetes research. 2021; 2021(?):6689414. doi: 10.1155/2021/6689414. [PMID: 34212051]
  • Juan Lei, Yu Zhou, Huakan Zhao, Yu Chen, Guifang Yan, Lei Wu, Yanquan Xu, Jiangang Zhang, Xiao Zhang, Jingchun Wang, Dingshan Li, Yongsheng Li. Dabigatran activates inflammation resolution by promoting fibrinogen-like protein 2 shedding and RvD5n-3 DPA production. Theranostics. 2021; 11(9):4251-4261. doi: 10.7150/thno.50182. [PMID: 33754059]
  • Anandita Pal, Adam H Metherel, Lauren Fiabane, Nicole Buddenbaum, Richard P Bazinet, Saame Raza Shaikh. Do Eicosapentaenoic Acid and Docosahexaenoic Acid Have the Potential to Compete against Each Other?. Nutrients. 2020 Dec; 12(12):. doi: 10.3390/nu12123718. [PMID: 33276463]
  • Siting Li, Zhangli Hu, Xuewei Yang, Yan Li. Effect of Nitrogen Sources on Omega-3 Polyunsaturated Fatty Acid Biosynthesis and Gene Expression in Thraustochytriidae sp. Marine drugs. 2020 Dec; 18(12):. doi: 10.3390/md18120612. [PMID: 33271856]
  • Kerry Flannagan, Sheila Gahagan, Arun Das, Raquel Burrows, Betsy Lozoff, Eduardo Villamor. Serum polyunsaturated fatty acids in infancy are associated with body composition in adolescence. Pediatric obesity. 2020 11; 15(11):e12656. doi: 10.1111/ijpo.12656. [PMID: 32426929]
  • Esteban A Gomez, Romain A Colas, Patricia R Souza, Rebecca Hands, Myles J Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli. Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Nature communications. 2020 10; 11(1):5420. doi: 10.1038/s41467-020-19176-z. [PMID: 33110080]
  • Sebastian Dams, Sandra Holasek, Melina Tsiountsioura, Martin Edelsbrunner, Pavel Dietz, Harald Koefeler, Daniela-Eugenia Malliga, Ayse Gürbüz, Nathalie Meier-Allard, Brigitte Poncza, Sonja Lackner, Elke Schwarzenberger, Yvonne Jansenberger, Manfred Lamprecht. Effects of a plant-based fatty acid supplement and a powdered fruit, vegetable and berry juice concentrate on omega-3-indices and serum micronutrient concentrations in healthy subjects. International journal of food sciences and nutrition. 2020 Sep; 71(6):769-780. doi: 10.1080/09637486.2020.1725960. [PMID: 32064970]
  • Melinda S Schaller, Mian Chen, Romain A Colas, Thomas A Sorrentino, Ann A Lazar, S Marlene Grenon, Jesmond Dalli, Michael S Conte. Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease. Journal of the American Heart Association. 2020 08; 9(15):e016113. doi: 10.1161/jaha.120.016113. [PMID: 32696697]
  • So-Ichiro Hirata, Takahiro Nagatake, Kento Sawane, Koji Hosomi, Tetsuya Honda, Sachiko Ono, Noriko Shibuya, Emiko Saito, Jun Adachi, Yuichi Abe, Junko Isoyama, Hidehiko Suzuki, Ayu Matsunaga, Takeshi Tomonaga, Hiroshi Kiyono, Kenji Kabashima, Makoto Arita, Jun Kunisawa. Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice. Allergy. 2020 08; 75(8):1939-1955. doi: 10.1111/all.14217. [PMID: 32027039]
  • Xiao-Fei Guo, Wen-Feng Tong, Yue Ruan, Andrew J Sinclair, Duo Li. Different metabolism of EPA, DPA and DHA in humans: A double-blind cross-over study. Prostaglandins, leukotrienes, and essential fatty acids. 2020 07; 158(?):102033. doi: 10.1016/j.plefa.2019.102033. [PMID: 31740197]
  • Maria K Pangopoulos, Jens M N Nolsøe, Simen G Antonsen, Romain A Colas, Jesmond Dalli, Marius Aursnes, Yngve Stenstrøm, Trond Vidar Hansen. Enzymatic studies with 3-oxa n-3 DPA. Bioorganic chemistry. 2020 03; 96(?):103653. doi: 10.1016/j.bioorg.2020.103653. [PMID: 32062066]
  • Ge Liu, Robert A Gibson, Damien Callahan, Xiao-Fei Guo, Duo Li, Andrew J Sinclair. Pure omega 3 polyunsaturated fatty acids (EPA, DPA or DHA) are associated with increased plasma levels of 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) in a short-term study in women. Food & function. 2020 Mar; 11(3):2058-2066. doi: 10.1039/c9fo02440a. [PMID: 32142084]
  • Xingyu Zhu, Shuangfei Li, Liangxu Liu, Siting Li, Yanqing Luo, Chuhan Lv, Boyu Wang, Christopher H K Cheng, Huapu Chen, Xuewei Yang. Genome Sequencing and Analysis of Thraustochytriidae sp. SZU445 Provides Novel Insights into the Polyunsaturated Fatty Acid Biosynthesis Pathway. Marine drugs. 2020 Feb; 18(2):. doi: 10.3390/md18020118. [PMID: 32085426]
  • Lauren A Roach, Kenneth G Russell, Kelly Lambert, Jane L Holt, Barbara J Meyer. Polyunsaturated fatty acid food frequency questionnaire validation in people with end stage renal disease on dialysis. Nutrition & dietetics: the journal of the Dietitians Association of Australia. 2020 02; 77(1):131-138. doi: 10.1111/1747-0080.12483. [PMID: 30338904]
  • Qiu-Lan Ma, Cansheng Zhu, Marco Morselli, Trent Su, Matteo Pelligrini, Zhengqi Lu, Mychica Jones, Paul Denver, Daniel Castro, Xuelin Gu, Frances Relampagos, Kaitlin Caoili, Bruce Teter, Sally A Frautschy, Gregory M Cole. The Novel Omega-6 Fatty Acid Docosapentaenoic Acid Positively Modulates Brain Innate Immune Response for Resolving Neuroinflammation at Early and Late Stages of Humanized APOE-Based Alzheimer's Disease Models. Frontiers in immunology. 2020; 11(?):558036. doi: 10.3389/fimmu.2020.558036. [PMID: 33178186]
  • Pablo Perez-Martinez, Niki Katsiki, Dimitri P Mikhailidis. The Role of n-3 Fatty Acids in Cardiovascular Disease: Back to the Future. Angiology. 2020 01; 71(1):10-16. doi: 10.1177/0003319719842005. [PMID: 30966756]
  • Hiroaki Saito, Hisashi Ioka. Lipids and Fatty Acids of Sea Hares Aplysia kurodai and Aplysia juliana: High Levels of Icosapentaenoic and n-3 Docosapentaenoic Acids. Journal of oleo science. 2019 Dec; 68(12):1199-1213. doi: 10.5650/jos.ess19137. [PMID: 31735747]
  • Nhien Nguyen, Michelle Dow, Blake Woodside, J Bruce German, Oswald Quehenberger, Pei-An Betty Shih. Food-Intake Normalization of Dysregulated Fatty Acids in Women with Anorexia Nervosa. Nutrients. 2019 Sep; 11(9):. doi: 10.3390/nu11092208. [PMID: 31540208]
  • D Carreño, P G Toral, E Pinloche, A Belenguer, D R Yáñez-Ruiz, G Hervás, N R McEwan, C J Newbold, P Frutos. Rumen bacterial community responses to DPA, EPA and DHA in cattle and sheep: A comparative in vitro study. Scientific reports. 2019 08; 9(1):11857. doi: 10.1038/s41598-019-48294-y. [PMID: 31413283]
  • Zhenxiao Zheng, Zhiyuan Dai, Yalun Cao, Qing Shen, Yiqi Zhang. Docosapentaenoic acid (DPA, 22:5n-3) ameliorates inflammation in an ulcerative colitis model. Food & function. 2019 Jul; 10(7):4199-4209. doi: 10.1039/c8fo02338g. [PMID: 31250861]
  • Gaetan Drouin, Vincent Rioux, Philippe Legrand. The n-3 docosapentaenoic acid (DPA): A new player in the n-3 long chain polyunsaturated fatty acid family. Biochimie. 2019 Apr; 159(?):36-48. doi: 10.1016/j.biochi.2019.01.022. [PMID: 30716358]
  • Chesney K Richter, Karl Stessy Bisselou, Tara M Nordgren, Lynette Smith, Adams Kusi Appiah, Nicholas Hein, Ann Anderson-Berry, Penny Kris-Etherton, Corrine Hanson, Ann C Skulas-Ray. n-3 Docosapentaenoic Acid Intake and Relationship with Plasma Long-Chain n-3 Fatty Acid Concentrations in the United States: NHANES 2003-2014. Lipids. 2019 04; 54(4):221-230. doi: 10.1002/lipd.12146. [PMID: 31025717]
  • Anne M van der Does, Marieke Heijink, Oleg A Mayboroda, Louise J Persson, Marianne Aanerud, Per Bakke, Tomas M Eagan, Pieter S Hiemstra, Martin Giera. Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019 03; 1864(3):224-233. doi: 10.1016/j.bbalip.2018.11.012. [PMID: 30528790]
  • Alok Patel, Leonidas Matsakas, Kateřina Hrůzová, Ulrika Rova, Paul Christakopoulos. Biosynthesis of Nutraceutical Fatty Acids by the Oleaginous Marine Microalgae Phaeodactylum tricornutum Utilizing Hydrolysates from Organosolv-Pretreated Birch and Spruce Biomass. Marine drugs. 2019 Feb; 17(2):. doi: 10.3390/md17020119. [PMID: 30781416]
  • Jørn Eivind Tungen, Lisa Gerstmann, Anders Vik, Roberta De Matteis, Romain Alexandre Colas, Jesmond Dalli, Nan Chiang, Charles Nicholas Serhan, Markus Kalesse, Trond Vidar Hansen. Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. Chemistry (Weinheim an der Bergstrasse, Germany). 2019 Jan; 25(6):1476-1480. doi: 10.1002/chem.201806029. [PMID: 30511787]
  • Gaetan Drouin, Daniel Catheline, Etienne Guillocheau, Pierre Gueret, Charlotte Baudry, Pascale Le Ruyet, Vincent Rioux, Philippe Legrand. Comparative effects of dietary n-3 docosapentaenoic acid (DPA), DHA and EPA on plasma lipid parameters, oxidative status and fatty acid tissue composition. The Journal of nutritional biochemistry. 2019 01; 63(?):186-196. doi: 10.1016/j.jnutbio.2018.09.029. [PMID: 30412907]
  • Quang Vu Nguyen, Hung Van Le, Don Viet Nguyen, Bunmi S Malau-Aduli, Peter D Nichols, Aduli E O Malau-Aduli. Enhancement of dairy sheep cheese eating quality with increased n-3 long-chain polyunsaturated fatty acids. Journal of dairy science. 2019 Jan; 102(1):211-222. doi: 10.3168/jds.2018-15215. [PMID: 30391173]
  • Aysegul Hanikoglu, Ertan Kucuksayan, Ferhat Hanikoglu, Tomris Ozben, Georgia Menounou, Anna Sansone, Chrys Chatgilialoglu, Giuseppe Di Bella, Carla Ferreri. Effects of Somatostatin and Vitamin C on the Fatty Acid Profile of Breast Cancer Cell Membranes. Anti-cancer agents in medicinal chemistry. 2019; 19(15):1899-1909. doi: 10.2174/1871520619666190930130732. [PMID: 31566138]
  • Natalie M Hohos, Kirstin J Cho, Delaney C Swindle, Amanda A Allshouse, Michael C Rudolph, Malgorzata E Skaznik-Wikiel. Fat-1 Transgene Is Associated With Improved Reproductive Outcomes. Endocrinology. 2018 12; 159(12):3981-3992. doi: 10.1210/en.2018-00723. [PMID: 30403782]
  • Xianrong Shao, Gizem Bor, Sabah Al-Hosayni, Stefan Salentinig, Anan Yaghmur. Structural characterization of self-assemblies of new omega-3 lipids: docosahexaenoic acid and docosapentaenoic acid monoglycerides. Physical chemistry chemical physics : PCCP. 2018 Oct; 20(37):23928-23941. doi: 10.1039/c8cp04256j. [PMID: 30209464]
  • Gaetan Drouin, Etienne Guillocheau, Daniel Catheline, Charlotte Baudry, Pascale Le Ruyet, Vincent Rioux, Philippe Legrand. Impact of n-3 Docosapentaenoic Acid Supplementation on Fatty Acid Composition in Rat Differs Depending upon Tissues and Is Influenced by the Presence of Dairy Lipids in the Diet. Journal of agricultural and food chemistry. 2018 Sep; 66(38):9976-9988. doi: 10.1021/acs.jafc.8b03069. [PMID: 30056717]
  • Xiao-Fei Guo, Andrew J Sinclair, Gunveen Kaur, Duo Li. Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice. Prostaglandins, leukotrienes, and essential fatty acids. 2018 09; 136(?):47-55. doi: 10.1016/j.plefa.2017.09.011. [PMID: 29113747]
  • Kimberly Pistorius, Patricia R Souza, Roberta De Matteis, Shani Austin-Williams, Karoline G Primdahl, Anders Vik, Francesca Mazzacuva, Romain A Colas, Raquel M Marques, Trond V Hansen, Jesmond Dalli. PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function. Cell chemical biology. 2018 06; 25(6):749-760.e9. doi: 10.1016/j.chembiol.2018.04.017. [PMID: 29805036]
  • Xiaoling Leng, Jacob J Kinnun, Andres T Cavazos, Samuel W Canner, Saame Raza Shaikh, Scott E Feller, Stephen R Wassall. All n-3 PUFA are not the same: MD simulations reveal differences in membrane organization for EPA, DHA and DPA. Biochimica et biophysica acta. Biomembranes. 2018 May; 1860(5):1125-1134. doi: 10.1016/j.bbamem.2018.01.002. [PMID: 29305832]
  • Romain A Colas, Patricia R Souza, Mary E Walker, Maudrian Burton, Zbigniew Zasłona, Annie M Curtis, Raquel M Marques, Jesmond Dalli. Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease. Circulation research. 2018 03; 122(6):855-863. doi: 10.1161/circresaha.117.312472. [PMID: 29437834]
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