Gynosaponin I (BioDeep_00000017397)

 

Secondary id: BioDeep_00000395791, BioDeep_00000622800

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol

化学式: C47H80O17 (916.5395230000001)
中文名称: 三七皂苷 Fd, 绞股蓝提取物, 七叶胆皂甙
谱图信息: 最多检出来源 Escherichia coli(natural_products) 80%

分子结构信息

SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)OC6C(C(C(C(O6)COC7C(C(C(CO7)O)O)O)O)O)O)C
InChI: InChI=1S/C47H80O17/c1-22(2)10-9-14-47(8,64-42-39(58)36(55)34(53)27(62-42)21-60-40-37(56)32(51)25(50)20-59-40)23-11-16-46(7)31(23)24(49)18-29-44(5)15-13-30(43(3,4)28(44)12-17-45(29,46)6)63-41-38(57)35(54)33(52)26(19-48)61-41/h10,23-42,48-58H,9,11-21H2,1-8H3

描述信息

Notoginsenoside Fd is a natural product found in Panax ginseng and Panax notoginseng with data available.
Gynosaponin I is found in tea. Gynosaponin I is a constituent of Panax notoginseng (ginseng).
Constituent of Panax notoginseng (ginseng). Gynosaponin I is found in tea.
Gynostemma Extract (Ginsenoside C-Mx1) is a natural product.
Gynostemma Extract (Ginsenoside C-Mx1) is a natural product.

同义名列表

9 个代谢物同义名

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol; 2-(hydroxymethyl)-6-[[12-hydroxy-4,4,8,10,14-pentamethyl-17-[6-methyl-2-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol; 2-{[2-(16-hydroxy-2,6,6,10,11-pentamethyl-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl)-6-methylhept-5-en-2-yl]oxy}-6-{[(3,4,5-trihydroxyoxan-2-yl)oxy]methyl}oxane-3,4,5-triol; Notoginsenoside Fd; Gynosaponin I; Gypenoside IX; STEVENLEAF; Ginsenoside C-Mx1; Gynostemma Extract



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaoshuang Wang, Liu Yang, Li Yang, Faping Xing, Hua Yang, Liyue Qin, Yunyi Lan, Hui Wu, Beibei Zhang, Hailian Shi, Cheng Lu, Fei Huang, Xiaojun Wu, Zhengtao Wang. Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators. Inflammation. 2017 Dec; 40(6):2137-2150. doi: 10.1007/s10753-017-0654-x. [PMID: 28822019]
  • Weixin Huang, Jiannan Huang, Meizhen Liao, Jijun Guo, Yuzhen Yang. [Analysis on the septum correction and plasma radiofrequency ablation combination therapy for nasal septum deviation]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. 2011 Apr; 25(8):352-3. doi: NULL. [PMID: 21761708]
  • Gui-Ying Liu, Xu-Wen Li, Nian-Bin Wang, Hong-Yu Zhou, Wei Wei, Ming-Yu Gui, Bin Yang, Yong-Ri Jin. Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer. Journal of Asian natural products research. 2010 Oct; 12(10):865-73. doi: 10.1080/10286020.2010.508035. [PMID: 20924900]
  • Y H Liu, Y F Liu, X X Guo. Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China. Acta pharmacologica Sinica. 2001 Dec; 22(12):1071-7. doi: . [PMID: 11749802]
  • G Qi, L Zhang, C Li. [Influence of gypenoside on serum lipoprotein and atherosclerosis in hyperlipidaemia animals]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1996 Sep; 21(9):562-4 inside back cover. doi: NULL. [PMID: 9772651]