Daptomycin (BioDeep_00000016774)
Secondary id: BioDeep_00000177750, BioDeep_00000897184
natural product Chemicals and Drugs
代谢物信息卡片
Daptomycin
化学式: C72H101N17O26 (1619.7103326)
中文名称: 达托霉素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1NC([C@H]([C@H](OC([C@@H](NC([C@@H](NC([C@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC(=O)O)NC(=O)[C@H](NC1=O)CCCN)=O)C)=O)CC(=O)O)=O)=O)CO)=O)[C@H](CC(=O)O)C)=O)CC(C2=CC=CC=C2N)=O)=O)C)NC([C@@H](NC([C@H](NC([C@H](CC3=CNC4=C3C=CC=C4)NC(CCCCCCCCC)=O)=O)CC(N)=O)=O)CC(=O)O)=O)=O
InChI: InChI=1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43+,44+,45-,46+,47+,48+,49+,50-,60+,61+/m1/s1
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
Same as: D01080
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
同义名列表
3 个代谢物同义名
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:600103
- KEGG: C12013
- KEGGdrug: D01080
- PubChem: 21585658
- Metlin: METLIN69252
- DrugBank: DB00080
- ChEMBL: CHEMBL4744444
- MeSH: Daptomycin
- CAS: 103060-53-3
- CAS: 103060-53-3, 500872-31-1
- MoNA: CCMSLIB00000078118
- PubChem: 14171
- NIKKAJI: J359.001A
- medchemexpress: HY-B0108
- KNApSAcK: 600103
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Diship Srivastava, Niladri Patra. Elucidating Daptomycin's Antibacterial Efficacy: Insights into the Tripartite Complex with Lipid II and Phospholipids in Bacterial Septum Membrane.
The journal of physical chemistry. B.
2024 May; 128(18):4414-4427. doi:
10.1021/acs.jpcb.4c00332. [PMID: 38690887] - Tatyana V Kravchenko, Alexander S Paramonov, Arsen M Kudzhaev, Svetlana S Efimova, Alexey S Khorev, Gulnara Kh Kudryakova, Igor A Ivanov, Alexey A Chistov, Anna A Baranova, Maxim S Krasilnikov, Olda A Lapchinskaya, Anton P Tyurin, Olga S Ostroumova, Ivan V Smirnov, Stanislav S Terekhov, Olga A Dontsova, Zakhar O Shenkarev, Vera A Alferova, Vladimir A Korshun. Gausemycin Antibiotic Family Acts via Ca2+-Dependent Membrane Targeting.
Journal of natural products.
2024 Apr; 87(4):664-674. doi:
10.1021/acs.jnatprod.3c00612. [PMID: 38362867] - Brianne R Zbylicki, Claire E Murphy, Jennifer A Petsche, Ute Müh, Horia A Dobrila, Theresa D Ho, Mikaela N Daum, Anthony G Pannullo, David S Weiss, Craig D Ellermeier. Identification of Clostridioides difficile mutants with increased daptomycin resistance.
Journal of bacteriology.
2024 Mar; 206(3):e0036823. doi:
10.1128/jb.00368-23. [PMID: 38376203] - Agathe Faure, Sylvie Manuse, Mathilde Gonin, Christophe Grangeasse, Jean-Michel Jault, Cédric Orelle. Daptomycin avoids drug resistance mediated by the BceAB transporter in Streptococcus pneumoniae.
Microbiology spectrum.
2024 Feb; 12(2):e0363823. doi:
10.1128/spectrum.03638-23. [PMID: 38214521] - Samavi Farnush Bint-E-Naser, Zeinab Jushkun Mohamed, Zhongmou Chao, Karan Bali, Róisín M Owens, Susan Daniel. Gram-Positive Bacterial Membrane-Based Biosensor for Multimodal Investigation of Membrane-Antibiotic Interactions.
Biosensors.
2024 Jan; 14(1):. doi:
10.3390/bios14010045. [PMID: 38248423] - Emilia Krok, Mareike Stephan, Rumiana Dimova, Lukasz Piatkowski. Tunable biomimetic bacterial membranes from binary and ternary lipid mixtures and their application in antimicrobial testing.
Biochimica et biophysica acta. Biomembranes.
2023 10; 1865(7):184194. doi:
10.1016/j.bbamem.2023.184194. [PMID: 37328023] - Anthony G Pannullo, Brianne R Zbylicki, Craig D Ellermeier. Identification of DraRS in Clostridioides difficile, a Two-Component Regulatory System That Responds to Lipid II-Interacting Antibiotics.
Journal of bacteriology.
2023 Jul; ?(?):e0016423. doi:
10.1128/jb.00164-23. [PMID: 37439672] - Deseree J Reid, Tapasyatanu Dash, Zhihan Wang, Craig A Aspinwall, Michael T Marty. Investigating Daptomycin-Membrane Interactions Using Native MS and Fast Photochemical Oxidation of Peptides in Nanodiscs.
Analytical chemistry.
2023 03; 95(11):4984-4991. doi:
10.1021/acs.analchem.2c05222. [PMID: 36888920] - Anthony G Pannullo, Ziqiang Guan, Howard Goldfine, Craig D Ellermeier. HexSDF Is Required for Synthesis of a Novel Glycolipid That Mediates Daptomycin and Bacitracin Resistance in C. difficile.
mBio.
2023 Feb; ?(?):e0339722. doi:
10.1128/mbio.03397-22. [PMID: 36786594] - Rutan Zhang, Hari Polenakovik, Ismael A Barreras Beltran, Adam Waalkes, Stephen J Salipante, Libin Xu, Brian J Werth. Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2022 10; 75(9):1641-1644. doi:
10.1093/cid/ciac341. [PMID: 35510938] - Greg A Somerville, Allison A Parrett, Joseph M Reed, Stewart G Gardner, Martha Morton, Robert Powers. Human Serum Alters the Metabolism and Antibiotic Susceptibility of Staphylococcus aureus.
Journal of proteome research.
2022 06; 21(6):1467-1474. doi:
10.1021/acs.jproteome.2c00073. [PMID: 35537087] - Takaaki Yamada, Midori Soda, Ruriko Nishida, Noriko Miyake, Yasutaka Maeshiro, Yasuhisa Oida, Yuji Yamashita, Nobuaki Egashira, Nobuyuki Shimono, Kiyoyuki Kitaichi, Ichiro Ieiri. Simplified daptomycin dosing regimen for adult patients with methicillin-resistant Staphylococcus aureus infections based on population pharmacokinetic analysis.
Drug metabolism and pharmacokinetics.
2022 Jun; 44(?):100444. doi:
10.1016/j.dmpk.2022.100444. [PMID: 35462110] - Elizabeth V K Ledger, Stéphane Mesnage, Andrew M Edwards. Human serum triggers antibiotic tolerance in Staphylococcus aureus.
Nature communications.
2022 04; 13(1):2041. doi:
10.1038/s41467-022-29717-3. [PMID: 35440121] - Ryan Moreira, Scott D Taylor. The Chiral Target of Daptomycin Is the 2R,2'S Stereoisomer of Phosphatidylglycerol.
Angewandte Chemie (International ed. in English).
2022 01; 61(4):e202114858. doi:
10.1002/anie.202114858. [PMID: 34843157] - Christoph J Slavetinsky, Janna N Hauser, Cordula Gekeler, Jessica Slavetinsky, André Geyer, Alexandra Kraus, Doris Heilingbrunner, Samuel Wagner, Michael Tesar, Bernhard Krismer, Sebastian Kuhn, Christoph M Ernst, Andreas Peschel. Sensitizing Staphylococcus aureus to antibacterial agents by decoding and blocking the lipid flippase MprF.
eLife.
2022 01; 11(?):. doi:
10.7554/elife.66376. [PMID: 35044295] - Shengnan Jiang, Hemu Zhuang, Feiteng Zhu, Xiang Wei, Junxiong Zhang, Lu Sun, Shujuan Ji, Haiping Wang, Dandan Wu, Feng Zhao, Rushuang Yan, Yunsong Yu, Yan Chen. The Role of mprF Mutations in Seesaw Effect of Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus Isolates.
Antimicrobial agents and chemotherapy.
2022 01; 66(1):e0129521. doi:
10.1128/aac.01295-21. [PMID: 34662187] - Rajalakshmi Valaiyapathi, Meng-San Wu, Alastair McGregor. Ground glass opacities are not always COVID-19: a case of acute eosinophilic pneumonitis caused by daptomycin.
Lancet (London, England).
2022 01; 399(10321):270. doi:
10.1016/s0140-6736(22)00009-5. [PMID: 35033220] - Chang-Hun Ji, Hiyoung Kim, Hyun-Woo Je, Haeun Kwon, Dongho Lee, Hahk-Soo Kang. Top-down synthetic biology approach for titer improvement of clinically important antibiotic daptomycin in Streptomyces roseosporus.
Metabolic engineering.
2022 01; 69(?):40-49. doi:
10.1016/j.ymben.2021.10.013. [PMID: 34737068] - Carla C C R de Carvalho, Agustina Taglialegna, Adriana E Rosato. Impact of PrsA on membrane lipid composition during daptomycin-resistance-mediated β-lactam sensitization in clinical MRSA strains.
The Journal of antimicrobial chemotherapy.
2021 12; 77(1):135-147. doi:
10.1093/jac/dkab356. [PMID: 34618036] - Carlo Pallotto, Francesco Sbrana, Andrea Ripoli, Tommaso Lupia, Silvia Corcione, Francesco Paciosi, Daniela Francisci, Maria Bruna Pasticci, Emanuela Sozio, Giacomo Bertolino, Novella Carannante, Carolina Rescigno, Antonio Carozza, Giovanni Di Caprio, Eleonora Taddei, Rita Murri, Massimo Fantoni, Michele Emdin, Alberto Aimo, Francesco Giuseppe De Rosa, Carlo Tascini. Daptomycin-based aminoglycoside-sparing therapy for streptococcal endocarditis: a retrospective multicenter study.
Journal of chemotherapy (Florence, Italy).
2021 Oct; 33(6):435-439. doi:
10.1080/1120009x.2020.1838830. [PMID: 33103614] - Yi-Hu Yi, Jiang-Lin Wang, Wen-Jun Yin, Wei-Hua Xu. Vancomycin or Daptomycin Plus a β-Lactam Versus Vancomycin or Daptomycin Alone for Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: A Systematic Review and Meta-Analysis.
Microbial drug resistance (Larchmont, N.Y.).
2021 Aug; 27(8):1044-1056. doi:
10.1089/mdr.2020.0350. [PMID: 33728980] - Pilar Blasco, Chunlei Zhang, Hoi Yee Chow, Guanhua Chen, Yongsheng Wu, Xuechen Li. An atomic perspective on improving daptomycin's activity.
Biochimica et biophysica acta. General subjects.
2021 08; 1865(8):129918. doi:
10.1016/j.bbagen.2021.129918. [PMID: 33965439] - Simona De Gregori, Annalisa De Silvestri, Maria Delfina Molinaro, Vincenzina Monzillo, Simona Biscarini, Marta Colaneri, Ilaria Gallazzi, Antonella Bartoli, Raffaele Bruno, Elena Seminari. Daptomycin Pharmacokinetics and Pharmacodynamics in Patients on Methadone Substitution Therapy.
European journal of drug metabolism and pharmacokinetics.
2021 Jul; 46(4):547-554. doi:
10.1007/s13318-021-00690-4. [PMID: 34231117] - Yan Lou, Yi-Xi Liu, Jiali Wang, Liefeng Cai, Lingjuan He, Xi Yang, Haoxiang Xu, Xiaoying He, Xiuyan Yang, Chunchun Wei, Hongfeng Huang. Population pharmacokinetics and individual analysis of daptomycin in kidney transplant recipients.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 Jul; 162(?):105818. doi:
10.1016/j.ejps.2021.105818. [PMID: 33771717] - Alaina Howe, Stavroula Sofou. Daptomycin-Induced Lipid Phases on Model Lipid Bilayers: Effect of Lipid Type and of Lipid Leaflet Order on Membrane Permeability.
The journal of physical chemistry. B.
2021 06; 125(22):5775-5785. doi:
10.1021/acs.jpcb.1c02047. [PMID: 34038100] - Masaru Samura, Keisuke Takada, Risako Yamamoto, Hayato Ito, Fumio Nagumo, Masaki Uchida, Takenori Kurata, Sakura Koshioka, Yuki Enoki, Kazuaki Taguchi, Ryuji Higashita, Norifumi Kunika, Koji Tanikawa, Kazuaki Matsumoto. Population Pharmacokinetic Analysis and Dosing Optimization Based on Unbound Daptomycin Concentration and Cystatin C in Nonobese Elderly Patients with Hypoalbuminemia and Chronic Kidney Disease.
Pharmaceutical research.
2021 Jun; 38(6):1041-1055. doi:
10.1007/s11095-021-03058-0. [PMID: 34013390] - Cameron C Hanna, Yann O Hermant, Paul W R Harris, Margaret A Brimble. Discovery, Synthesis, and Optimization of Peptide-Based Antibiotics.
Accounts of chemical research.
2021 04; 54(8):1878-1890. doi:
10.1021/acs.accounts.0c00841. [PMID: 33750106] - Makoto Kai, Ryota Tanaka, Yosuke Suzuki, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. Simultaneous quantification of plasma levels of 12 antimicrobial agents including carbapenem, anti-methicillin-resistant Staphylococcus aureus agent, quinolone and azole used in intensive care unit using UHPLC-MS/MS method.
Clinical biochemistry.
2021 Apr; 90(?):40-49. doi:
10.1016/j.clinbiochem.2021.01.012. [PMID: 33539809] - Olga O Vlashyn, Ashley M Lorenz, Mohammad M Sobhanie, Jessica M Smith, Megan Bond, Lynn Wardlow. Safety outcomes with high-dose daptomycin in patients with acute kidney injury and/or end-stage renal disease.
Journal of clinical pharmacy and therapeutics.
2021 Apr; 46(2):363-368. doi:
10.1111/jcpt.13289. [PMID: 33016513] - Nicolas Gregoire, Alexia Chauzy, Julien Buyck, Blandine Rammaert, William Couet, Sandrine Marchand. Clinical Pharmacokinetics of Daptomycin.
Clinical pharmacokinetics.
2021 03; 60(3):271-281. doi:
10.1007/s40262-020-00968-x. [PMID: 33313994] - Ryota Tanaka, Makoto Kai, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. High-throughput and wide-range simultaneous determination of linezolid, daptomycin and tedizolid in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2021 Feb; 194(?):113764. doi:
10.1016/j.jpba.2020.113764. [PMID: 33298382] - Antje Pokorny, Paulo F Almeida. The Antibiotic Peptide Daptomycin Functions by Reorganizing the Membrane.
The Journal of membrane biology.
2021 02; 254(1):97-108. doi:
10.1007/s00232-021-00175-0. [PMID: 33620544] - Andreas Körtge, Jolanta Majcher-Peszynska, Benjamin Heskamp, Reinhold Wasserkort, Steffen Mitzner. Antibiotics Removal by Continuous Venovenous Hemofiltration with a Novel Asymmetric Triacetate Membrane Hemofilter: An in vitro Study.
Blood purification.
2021; 50(6):899-905. doi:
10.1159/000513417. [PMID: 33631754] - Yutaro Yamamoto, Tetsuya Saita, Asuki Oka, Hiroto Kataoka, Yuta Yamamoto, Masashi Shin. [Development of a Sensitive Enzyme-linked Immunosorbent Assay for Daptomycin].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2021; 141(3):427-431. doi:
10.1248/yakushi.20-00224. [PMID: 33642512] - Asim Ali Shah, Shahid Ahmad Abbasi, Yasir Ali, Ayesha Maqbool. In vitro efficacy of Daptomycin against clinical isolates of Methicillin-resistant Staphylococcus aureus (MRSA).
JPMA. The Journal of the Pakistan Medical Association.
2021 Jan; 71(1(B)):338-340. doi:
10.47391/jpma.145. [PMID: 35157675] - Francesca Zuttion, Adai Colom, Stefan Matile, Denes Farago, Frédérique Pompeo, Janos Kokavecz, Anne Galinier, James Sturgis, Ignacio Casuso. High-speed atomic force microscopy highlights new molecular mechanism of daptomycin action.
Nature communications.
2020 12; 11(1):6312. doi:
10.1038/s41467-020-19710-z. [PMID: 33298927] - Takuhei Yamamoto, Kousuke Sakamoto, Yukihiro Esaka, Bunji Uno. Highly Sensitive Fluorescence Detection of Daptomycin in Murine Samples through Derivatization with 2,3-Naphthalenedialdehyde.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2020 Oct; 36(10):1285-1288. doi:
10.2116/analsci.20n010. [PMID: 32378527] - Andrea Mescola, Gregorio Ragazzini, Andrea Alessandrini. Daptomycin Strongly Affects the Phase Behavior of Model Lipid Bilayers.
The journal of physical chemistry. B.
2020 10; 124(39):8562-8571. doi:
10.1021/acs.jpcb.0c06640. [PMID: 32886515] - William Brewer, Johnathan Harrison, Holly E Saito, Elizabeth M Fozo. Induction of Daptomycin Tolerance in Enterococcus faecalis by Fatty Acid Combinations.
Applied and environmental microbiology.
2020 10; 86(20):. doi:
10.1128/aem.01178-20. [PMID: 32801181] - Takehiro Yamada, Shuhei Ishikawa, Nobuhisa Ishiguro, Masaki Kobayashi, Ken Iseki. Evaluation of Daptomycin-Induced Cellular Membrane Injury in Skeletal Muscle.
Biological & pharmaceutical bulletin.
2020 Sep; 43(9):1338-1345. doi:
10.1248/bpb.b20-00217. [PMID: 32581153] - Keishi Yamasaki, Keiki Sakurama, Koji Nishi, Hiroshi Watanabe, Toru Maruyama, Hakaru Seo, Masaki Otagiri, Kazuaki Taguchi. Characterization of the Interaction of Daptomycin With Site II on Human Serum Albumin.
Journal of pharmaceutical sciences.
2020 09; 109(9):2919-2924. doi:
10.1016/j.xphs.2020.06.011. [PMID: 32565355] - Daniel Balleza, Andrea Mescola, Andrea Alessandrini. Model lipid systems and their use to evaluate the phase state of biomembranes, their mechanical properties and the effect of non-conventional antibiotics: the case of daptomycin.
European biophysics journal : EBJ.
2020 Jul; 49(5):401-408. doi:
10.1007/s00249-020-01445-w. [PMID: 32632743] - David Beriashvili, Norman R Spencer, Thorsten Dieckmann, Michael Overduin, Michael Palmer. Characterization of multimeric daptomycin bound to lipid nanodiscs formed by calcium-tolerant styrene-maleic acid copolymer.
Biochimica et biophysica acta. Biomembranes.
2020 06; 1862(6):183234. doi:
10.1016/j.bbamem.2020.183234. [PMID: 32145282] - M A Zimmer, E Haffner, C W Weisser, G Mols. [Daptomycin-induced eosinophilic pneumonia associated with an early endoprosthesis infection].
Der Anaesthesist.
2020 06; 69(6):414-420. doi:
10.1007/s00101-020-00765-y. [PMID: 32270225] - Yingzi Huang, Guozhong Lv, Linlin Hu, Yunfu Wu, Nan Guo, Yugang Zhu, Lingtao Ding, Qing Li, Songqiao Liu, Yi Yang, Hua Shao. Efficacy and Safety of High Vs Standard Daptomycin Doses Examined in Chinese Patients With Severe Burn Injuries by Pharmacokinetic Evaluation.
Journal of burn care & research : official publication of the American Burn Association.
2020 05; 41(3):705-713. doi:
10.1093/jbcr/iraa020. [PMID: 32006005] - Alexia S Alvarez, Oluseyi Oyerinde, Justin P Reinert. Drug-Induced Kidney Disease Associated With Selected Antibiotics.
The Senior care pharmacist.
2020 May; 35(5):225-229. doi:
10.4140/tcp.n.2020.225. [PMID: 32340659] - Giacomo Luci, Federico Cucchiara, Laura Ciofi, Marianna Lastella, Romano Danesi, Antonello Di Paolo. A new validated HPLC-UV method for therapeutic monitoring of daptomycin in comparison with reference mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2020 Apr; 182(?):113132. doi:
10.1016/j.jpba.2020.113132. [PMID: 32004774] - Motozumi Ando, Hiroaki Nishioka, Shinji Nakasako, Eriko Kuramoto, Mai Ikemura, Hiroki Kamei, Yumi Sono, Nobuyuki Sugioka, Shoji Fukushima, Tohru Hashida. Observational retrospective single-centre study in Japan to assess the clinical significance of serum daptomycin levels in creatinine phosphokinase elevation.
Journal of clinical pharmacy and therapeutics.
2020 Apr; 45(2):290-297. doi:
10.1111/jcpt.13061. [PMID: 31696963] - Tomoyuki Yamada, Yukimasa Ooi, Kazutaka Oda, Yuriko Shibata, Fumiko Kawanishi, Kaoru Suzuki, Masami Nishihara, Takashi Nakano, Miyako Yoshida, Takahiro Uchida, Takahiro Katsumata, Akira Ukimura. Observational study to determine the optimal dose of daptomycin based on pharmacokinetic/pharmacodynamic analysis.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2020 Apr; 26(4):379-384. doi:
10.1016/j.jiac.2019.11.002. [PMID: 31836287] - Ariane Roujansky, Mathieu Martin, Camille Gomart, Anne Hulin, Roman Mounier. Multidrug-Resistant Staphylococcus epidermidis Ventriculostomy-Related Infection Successfully Treated by Intravenous Ceftaroline after Failure of Daptomycin Treatment.
World neurosurgery.
2020 Apr; 136(?):221-225. doi:
10.1016/j.wneu.2020.01.013. [PMID: 31931253] - Daniel Tuerff, Marina Nunez. More Frequent Premature Antibiotic Discontinuations and Acute Kidney Injury in the Outpatient Setting With Vancomycin Compared to Daptomycin.
Journal of clinical pharmacology.
2020 03; 60(3):384-390. doi:
10.1002/jcph.1536. [PMID: 31630403] - Steven Y C Tong, David C Lye, Dafna Yahav, Archana Sud, J Owen Robinson, Jane Nelson, Sophia Archuleta, Matthew A Roberts, Alan Cass, David L Paterson, Hong Foo, Mical Paul, Stephen D Guy, Adrian R Tramontana, Genevieve B Walls, Stephen McBride, Narin Bak, Niladri Ghosh, Benjamin A Rogers, Anna P Ralph, Jane Davies, Patricia E Ferguson, Ravindra Dotel, Genevieve L McKew, Timothy J Gray, Natasha E Holmes, Simon Smith, Morgyn S Warner, Shirin Kalimuddin, Barnaby E Young, Naomi Runnegar, David N Andresen, Nicholas A Anagnostou, Sandra A Johnson, Mark D Chatfield, Allen C Cheng, Vance G Fowler, Benjamin P Howden, Niamh Meagher, David J Price, Sebastiaan J van Hal, Matthew V N O'Sullivan, Joshua S Davis. Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial.
JAMA.
2020 02; 323(6):527-537. doi:
10.1001/jama.2020.0103. [PMID: 32044943] - Hiroko Tsukada, Yasuhiro Tsuji, Takuya Yamashina, Minako Tsuruta, Yoichi Hiraki, Moeko Tsuruyama, Chika Ogami, Hitoshi Kawasuji, Ippei Sakamaki, Yoshihiro Yamamoto. Pharmacokinetics and pharmacodynamics of daptomycin in a clinical setting.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2020 Feb; 26(2):230-235. doi:
10.1016/j.jiac.2019.08.017. [PMID: 31735632] - Yutaro Yamamoto, Yuta Yamamoto, Tetsuya Saita, Masashi Shin. [Localization and Accumulation Studies of Daptomycin in Rats Kidney Using Immunohistochemistry].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2020; 140(4):569-576. doi:
10.1248/yakushi.19-00233. [PMID: 32238639] - Chunyi Tong, Li Li, Feng Xiao, Jialong Fan, Xianghua Zhong, Xuanming Liu, Bin Liu, Zhaohui Wu, Jianqun Zhou. Daptomycin and AgNP co-loaded rGO nanocomposites for specific treatment of Gram-positive bacterial infection in vitro and in vivo.
Biomaterials science.
2019 Dec; 7(12):5097-5111. doi:
10.1039/c9bm01229j. [PMID: 31524205] - S Piva, Antonello Di Paolo, Laura Galeotti, Francesco Ceccherini, Francesco Cordoni, Liana Signorini, Tommaso Togni, Amedeo De Nicolò, Frank A Rasulo, Nazzareno Fagoni, N Latronico, Antonio D'Avolio. Daptomycin Plasma and CSF Levels in Patients with Healthcare-Associated Meningitis.
Neurocritical care.
2019 08; 31(1):116-124. doi:
10.1007/s12028-018-0657-y. [PMID: 30607829] - Toshiharu Urakami, Yohei Hamada, Yusuke Oka, Tomohide Okinaka, Hiroki Yamakuchi, Hiroki Magarifuchi, Yosuke Aoki. Clinical pharmacokinetic and pharmacodynamic analysis of daptomycin and the necessity of high-dose regimen in Japanese adult patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2019 Jun; 25(6):437-443. doi:
10.1016/j.jiac.2019.01.011. [PMID: 30782427] - Ayami Sato, Tetsuo Yamaguchi, Masakaze Hamada, Daisuke Ono, Shiro Sonoda, Takashi Oshiro, Makoto Nagashima, Keisuke Kato, Shinichi Okazumi, Ryoji Katoh, Yoshikazu Ishii, Kazuhiro Tateda. Morphological and Biological Characteristics of Staphylococcus aureus Biofilm Formed in the Presence of Plasma.
Microbial drug resistance (Larchmont, N.Y.).
2019 Jun; 25(5):668-676. doi:
10.1089/mdr.2019.0068. [PMID: 31099708] - Jun Taek Oh, Cara Cassino, Raymond Schuch. Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus.
Antimicrobial agents and chemotherapy.
2019 06; 63(6):. doi:
10.1128/aac.02616-18. [PMID: 30936103] - Ming-Tao Lee, Wei-Chin Hung, Huey W Huang. Rhombohedral trap for studying molecular oligomerization in membranes: application to daptomycin.
Soft matter.
2019 May; 15(21):4326-4333. doi:
10.1039/c9sm00323a. [PMID: 31070654] - Philippe Gaudard, Marine Saour, David Morquin, Hélène David, Jacob Eliet, Maxime Villiet, Jean-Pierre Daures, Pascal Colson. Acute kidney injury during daptomycin versus vancomycin treatment in cardiovascular critically ill patients: a propensity score matched analysis.
BMC infectious diseases.
2019 May; 19(1):438. doi:
10.1186/s12879-019-4077-1. [PMID: 31109283] - Michele Dei Cas, Eleonora Casagni, Veniero Gambaro, Elena Cesari, Gabriella Roda. Determination of daptomycin in human plasma and breast milk by UPLC/MS-MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 May; 1116(?):38-43. doi:
10.1016/j.jchromb.2019.03.036. [PMID: 30953921] - Matthew Geriak, Fadi Haddad, Khulood Rizvi, Warren Rose, Ravina Kullar, Kerry LaPlante, Marie Yu, Logan Vasina, Krista Ouellette, Marcus Zervos, Victor Nizet, George Sakoulas. Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia.
Antimicrobial agents and chemotherapy.
2019 05; 63(5):. doi:
10.1128/aac.02483-18. [PMID: 30858203] - E Sweeney, A M Lovering, K E Bowker, A P MacGowan, S M Nelson. An in vitro biofilm model of Staphylococcus aureus infection of bone.
Letters in applied microbiology.
2019 Apr; 68(4):294-302. doi:
10.1111/lam.13131. [PMID: 30770577] - Ryota Tanaka, Yosuke Suzuki, Koji Goto, Norihisa Yasuda, Hironori Koga, Shinya Kai, Yoshifumi Ohchi, Yuhki Sato, Takaaki Kitano, Hiroki Itoh. Development and validation of sensitive and selective quantification of total and free daptomycin in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2019 Feb; 165(?):56-64. doi:
10.1016/j.jpba.2018.11.047. [PMID: 30502552] - Garyfallia Poulakou, Georgios Renieris, Labros Sabrakos, Olympia Zarkotou, Katherine Themeli-Digalaki, Efstathia Perivolioti, Eleni Kraniotaki, Evangelos J Giamarellos-Bourboulis, Nikolaos Zavras. Daptomycin as adjunctive treatment for experimental infection by Acinetobacter baumannii with resistance to colistin.
International journal of antimicrobial agents.
2019 Feb; 53(2):190-194. doi:
10.1016/j.ijantimicag.2018.10.024. [PMID: 30391645] - J Barberan, J Mensa, A Artero, F Epelde, J C Rodriguez, J Ruiz-Morales, J L Calleja, J M Guerra, I Martínez-Gil, M J Giménez, J J Granizo, L Aguilar. Factors associated with development of nephrotoxicity in patients treated with vancomycin versus daptomycin for severe Gram-positive infections: A practice-based study.
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia.
2019 Feb; 32(1):22-30. doi:
NULL. [PMID: 30630306] - Federica Andreoni, Masanori Toyofuku, Carmen Menzi, Ratchara Kalawong, Srikanth Mairpady Shambat, Patrice François, Annelies S Zinkernagel, Leo Eberl. Antibiotics Stimulate Formation of Vesicles in Staphylococcus aureus in both Phage-Dependent and -Independent Fashions and via Different Routes.
Antimicrobial agents and chemotherapy.
2019 02; 63(2):. doi:
10.1128/aac.01439-18. [PMID: 30509943] - Gabriela Seydlová, Albert Sokol, Petra Lišková, Ivo Konopásek, Radovan Fišer. Daptomycin Pore Formation and Stoichiometry Depend on Membrane Potential of Target Membrane.
Antimicrobial agents and chemotherapy.
2019 01; 63(1):. doi:
10.1128/aac.01589-18. [PMID: 30323037] - Nicolas Grégoire, Sandrine Marchand, Martine Ferrandière, Sigismond Lasocki, Philippe Seguin, Mickaël Vourc'h, Mathilde Barbaz, Thomas Gaillard, Yoann Launey, Karim Asehnoune, William Couet, Olivier Mimoz. Population pharmacokinetics of daptomycin in critically ill patients with various degrees of renal impairment.
The Journal of antimicrobial chemotherapy.
2019 01; 74(1):117-125. doi:
10.1093/jac/dky374. [PMID: 30295740] - Alicia Galar, Patricia Muñoz, Maricela Valerio, Emilia Cercenado, Xandra García-González, Almudena Burillo, Mar Sánchez-Somolinos, Miriam Juárez, Eduardo Verde, Emilio Bouza. Current use of daptomycin and systematic therapeutic drug monitoring: Clinical experience in a tertiary care institution.
International journal of antimicrobial agents.
2019 Jan; 53(1):40-48. doi:
10.1016/j.ijantimicag.2018.09.015. [PMID: 30243587] - Geeta Gyamlani, Praveen K Potukuchi, Fridtjof Thomas, Oguz Akbilgic, Melissa Soohoo, Elani Streja, Adnan Naseer, Keiichi Sumida, Miklos Z Molnar, Kamyar Kalantar-Zadeh, Csaba P Kovesdy. Vancomycin-Associated Acute Kidney Injury in a Large Veteran Population.
American journal of nephrology.
2019; 49(2):133-142. doi:
10.1159/000496484. [PMID: 30677750] - Christoph M Ernst, Christoph J Slavetinsky, Sebastian Kuhn, Janna N Hauser, Mulugeta Nega, Nagendra N Mishra, Cordula Gekeler, Arnold S Bayer, Andreas Peschel. Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance.
mBio.
2018 12; 9(6):. doi:
10.1128/mbio.01659-18. [PMID: 30563904] - David Beriashvili, Robert Taylor, Braden Kralt, Nooran Abu Mazen, Scott D Taylor, Michael Palmer. Mechanistic studies on the effect of membrane lipid acyl chain composition on daptomycin pore formation.
Chemistry and physics of lipids.
2018 11; 216(?):73-79. doi:
10.1016/j.chemphyslip.2018.09.015. [PMID: 30278162] - Laure Peyro Saint Paul, Maxence Ficheux, Danièle Debruyne, Magalie Loilier, Nicolas Bouvier, Rémy Morello, Renaud Verdon, Elsa Le Blanc, Vincent Cattoir, Thierry Lobbedez. Pharmacokinetics of 300 mg/d Intraperitoneal Daptomycin: New Insight from the DaptoDP Study.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2018 Nov; 38(6):463-466. doi:
10.3747/pdi.2017.00256. [PMID: 30413641] - Raquel Ramírez-Martín, Patricia Pérez-Rodríguez, Alicia Rico-Nieto, Coro Mauleón-Ladrero. [Early onset rhabdomyolysis and acute renal failure associated with the administration of daptomycin. A Case report and literature review].
Revista espanola de geriatria y gerontologia.
2018 Nov; 53(6):362-363. doi:
10.1016/j.regg.2018.05.008. [PMID: 30025723] - Antje Pokorny, Tala O Khatib, Heather Stevenson. A Quantitative Model of Daptomycin Binding to Lipid Bilayers.
The journal of physical chemistry. B.
2018 10; 122(39):9137-9146. doi:
10.1021/acs.jpcb.8b07503. [PMID: 30247034] - Christen Ravn, Inês S Ferreira, Elena Maiolo, Søren Overgaard, Andrej Trampuz. Microcalorimetric detection of staphylococcal biofilm growth on various prosthetic biomaterials after exposure to daptomycin.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2018 10; 36(10):2809-2816. doi:
10.1002/jor.24040. [PMID: 29744925] - Chih-Ning Cheng, Shu-Wen Lin, Chien-Chih Wu. Early linezolid-associated lactic acidosis in a patient with Child's class C liver cirrhosis and end stage renal disease.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2018 Oct; 24(10):841-844. doi:
10.1016/j.jiac.2018.02.002. [PMID: 29503228] - Yukari Miyadera, Takafumi Naito, Takahiro Yamada, Junichi Kawakami. Simple LC-MS/MS Methods Using Core-Shell Octadecylsilyl Microparticulate for the Quantitation of Total and Free Daptomycin in Human Plasma.
Therapeutic drug monitoring.
2018 10; 40(5):589-595. doi:
10.1097/ftd.0000000000000535. [PMID: 30086083] - Ming-Tao Lee, Pei-Yin Yang, Nicholas E Charron, Meng-Hsuan Hsieh, Yu-Yung Chang, Huey W Huang. Comparison of the Effects of Daptomycin on Bacterial and Model Membranes.
Biochemistry.
2018 09; 57(38):5629-5639. doi:
10.1021/acs.biochem.8b00818. [PMID: 30153001] - Jill M Butterfield-Cowper, Thomas P Lodise, Manjunath P Pai. A Fixed versus Weight-Based Dosing Strategy of Daptomycin May Improve Safety in Obese Adults.
Pharmacotherapy.
2018 09; 38(9):981-985. doi:
10.1002/phar.2157. [PMID: 29906315] - Antonio C Arrieta, John S Bradley, Myra W Popejoy, Mekki Bensaci, Anjana Grandhi, Paula Bokesch, Chad Glasser, Lihong Du, Hernando Patino, Nicholas A Kartsonis. Randomized Multicenter Study Comparing Safety and Efficacy of Daptomycin Versus Standard-of-care in Pediatric Patients With Staphylococcal Bacteremia.
The Pediatric infectious disease journal.
2018 09; 37(9):893-900. doi:
10.1097/inf.0000000000001926. [PMID: 29406465] - Jennifer K Bender, Vincent Cattoir, Kristin Hegstad, Ewa Sadowy, Teresa M Coque, Henrik Westh, Anette M Hammerum, Kirsten Schaffer, Karen Burns, Stephen Murchan, Carla Novais, Ana R Freitas, Luísa Peixe, Maria Del Grosso, Annalisa Pantosti, Guido Werner. Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: Towards a common nomenclature.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
2018 09; 40(?):25-39. doi:
10.1016/j.drup.2018.10.002. [PMID: 30447411] - Nicholas K Goldner, Christopher Bulow, Kevin Cho, Meghan Wallace, Fong-Fu Hsu, Gary J Patti, C A Burnham, Paul Schlesinger, Gautam Dantas. Mechanism of High-Level Daptomycin Resistance in Corynebacterium striatum.
mSphere.
2018 08; 3(4):. doi:
10.1128/mspheredirect.00371-18. [PMID: 30089649] - Julian Hösl, André Gessner, Nahed El-Najjar. Liquid chromatography-tandem mass spectrometry for the quantification of moxifloxacin, ciprofloxacin, daptomycin, caspofungin, and isavuconazole in human plasma.
Journal of pharmaceutical and biomedical analysis.
2018 Aug; 157(?):92-99. doi:
10.1016/j.jpba.2018.05.015. [PMID: 29777985] - A Soraluce, E Asín-Prieto, A Rodríguez-Gascón, H Barrasa, J Maynar, E Carcelero, D Soy, A Isla. Population pharmacokinetics of daptomycin in critically ill patients.
International journal of antimicrobial agents.
2018 Aug; 52(2):158-165. doi:
10.1016/j.ijantimicag.2018.03.008. [PMID: 29572042] - Charalampos Antachopoulos, Stavroula Ilia, Paschalis Kadiltzoglou, Eirini Baira, Aristides Dokoumetzidis, Evangelos Gikas, Eleni Volakli, Maria Sdougka, George Briassoulis, Emmanuel Roilides. Pharmacokinetics of Daptomycin in Critically Ill Pediatric Patients.
Antimicrobial agents and chemotherapy.
2018 06; 62(6):. doi:
10.1128/aac.02462-17. [PMID: 29610198] - Francisco Arnaiz de Las Revillas, Marta Fernandez-Sampedro, Ana María Arnaiz-García, Manuel Gutierrez-Cuadra, Carlos Armiñanzas, Ivana Pulitani, Alejandro Ponton, Valentin Tascon, Ivan García, María Carmen Fariñas. Daptomycin treatment in Gram-positive vascular graft infections.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2018 Mar; 68(?):69-73. doi:
10.1016/j.ijid.2018.01.009. [PMID: 29373845] - Yoshitsugu Higashi, Shigeki Nakamura, Yasuhiro Tsuji, Chika Ogami, Kaoru Matsumoto, Koyomi Kawago, Kotaro Tokui, Ryuji Hayashi, Ippei Sakamaki, Yoshihiro Yamamoto. Daptomycin-induced Eosinophilic Pneumonia and a Review of the Published Literature.
Internal medicine (Tokyo, Japan).
2018 Jan; 57(2):253-258. doi:
10.2169/internalmedicine.9010-17. [PMID: 29093391] - Mark A T Blaskovich, Karl A Hansford, Yujing Gong, Mark S Butler, Craig Muldoon, Johnny X Huang, Soumya Ramu, Alberto B Silva, Mu Cheng, Angela M Kavanagh, Zyta Ziora, Rajaratnam Premraj, Fredrik Lindahl, Tanya A Bradford, June C Lee, Tomislav Karoli, Ruby Pelingon, David J Edwards, Maite Amado, Alysha G Elliott, Wanida Phetsang, Noor Huda Daud, Johan E Deecke, Hanna E Sidjabat, Sefetogi Ramaologa, Johannes Zuegg, Jason R Betley, Andrew P G Beevers, Richard A G Smith, Jason A Roberts, David L Paterson, Matthew A Cooper. Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.
Nature communications.
2018 01; 9(1):22. doi:
10.1038/s41467-017-02123-w. [PMID: 29295973] - Yu-Jui Chang, Mel S Lee, Chen-Hsiang Lee, Po-Chun Lin, Feng-Chih Kuo. Daptomycin treatment in patients with resistant staphylococcal periprosthetic joint infection.
BMC infectious diseases.
2017 11; 17(1):736. doi:
10.1186/s12879-017-2842-6. [PMID: 29187163] - Mark A Kreutzberger, Antje Pokorny, Paulo F Almeida. Daptomycin-Phosphatidylglycerol Domains in Lipid Membranes.
Langmuir : the ACS journal of surfaces and colloids.
2017 11; 33(47):13669-13679. doi:
10.1021/acs.langmuir.7b01841. [PMID: 29130685] - Hideki Hashimoto, Makoto Saito, Naoki Kanda, Takehito Yamamoto, Makiko Mieno, Shuji Hatakeyama. Dose-dependent effect of daptomycin on the artificial prolongation of prothrombin time in coagulation abnormalities: in vitro verification.
BMC pharmacology & toxicology.
2017 11; 18(1):74. doi:
10.1186/s40360-017-0180-3. [PMID: 29179737] - Robert Taylor, David Beriashvili, Scott Taylor, Michael Palmer. Daptomycin Pore Formation Is Restricted by Lipid Acyl Chain Composition.
ACS infectious diseases.
2017 11; 3(11):797-801. doi:
10.1021/acsinfecdis.7b00138. [PMID: 29048870] - Jérémie Diolez, Nicolas Venisse, Simohamed Belmouaz, Marc-André Bauwens, Frank Bridoux, Guillaume Beraud. Pilot Pharmacokinetic Study of High-Dose Daptomycin in Hemodialysis Patients With Infected Medical Devices.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2017 11; 70(5):732-734. doi:
10.1053/j.ajkd.2017.05.011. [PMID: 28645706] - Jin Zhang, Walter R P Scott, Frank Gabel, Miao Wu, Ruqaiba Desmond, JungHwan Bae, Giuseppe Zaccai, W Russ Algar, Suzana K Straus. On the quest for the elusive mechanism of action of daptomycin: Binding, fusion, and oligomerization.
Biochimica et biophysica acta. Proteins and proteomics.
2017 Nov; 1865(11 Pt B):1490-1499. doi:
10.1016/j.bbapap.2017.07.020. [PMID: 28844744] - Elizabeth V K Ledger, Vera Pader, Andrew M Edwards. Enterococcus faecalis and pathogenic streptococci inactivate daptomycin by releasing phospholipids.
Microbiology (Reading, England).
2017 Oct; 163(10):1502-1508. doi:
10.1099/mic.0.000529. [PMID: 28942757] - Mengyao Wang, Yue Wu, Yong He, Xiaoxiao Su, Hui Ouyang, Zhifeng Fu. Antibiotic-affinity strategy for bioluminescent detection of viable Gram-positive bacteria using daptomycin as recognition agent.
Analytica chimica acta.
2017 Sep; 987(?):91-97. doi:
10.1016/j.aca.2017.08.030. [PMID: 28916044]