Lypressin (BioDeep_00000016490)

Main id: BioDeep_00000006422

 

PANOMIX_OTCML-2023


代谢物信息卡片


[Lys8]-Vasopressin TFA

化学式: C46H65N13O12S2 (1055.431685)
中文名称: 赖氨加压素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N
InChI: InChI=1S/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29-,30-,31-,32-,33-,34-,35-/m0/s1

描述信息

H - Systemic hormonal preparations, excl. sex hormones and insulins > H01 - Pituitary and hypothalamic hormones and analogues > H01B - Posterior pituitary lobe hormones > H01BA - Vasopressin and analogues
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C80212 - Antidiuretic Hormone Analogue
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents > D014667 - Vasopressins
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D045283 - Natriuretic Agents > D050034 - Antidiuretic Agents
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase[1][2].
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase[1][2].

同义名列表

5 个代谢物同义名

[Lys8]-Vasopressin TFA; Lypressin; Lysine vasopressin; [Lys8]-Vasopressin; Lysipressin



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Justin M Belcher, Xavier Vela Parada, Douglas A Simonetto, Luis A Juncos, Nithin Karakala, Hani M Wadei, Pratima Sharma, Kevin R Regner, Mitra K Nadim, Guadalupe Garcia-Tsao, Juan Carlos Q Velez, Samir M Parikh, Raymond T Chung, Andrew S Allegretti. Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2022 05; 79(5):737-745. doi: 10.1053/j.ajkd.2021.08.016. [PMID: 34606933]
  • Luciana Marcondes Ferreira, Débora Raquel Terrabuio, Caroline Marcondes Ferreira, Daniel Ferraz de Campos Mazo, Luciana Bertocco de Paiva Haddad. COST EFFECTIVENESS OF USING TERLIPRESSIN TO TREAT HEPATORENAL SYNDROME. Arquivos de gastroenterologia. 2022 Apr; 59(2):268-274. doi: 10.1590/s0004-2803.202202000-48. [PMID: 35830040]
  • Anand V Kulkarni, Sowmya Tirumalige Ravikumar, Harshvardhan Tevethia, Madhumita Premkumar, Karan Kumar, Mithun Sharma, Rajesh Gupta, Padaki Nagaraja Rao, Duvvuru Nageshwar Reddy. Safety and efficacy of terlipressin in acute-on-chronic liver failure with hepatorenal syndrome-acute kidney injury (HRS-AKI): a prospective cohort study. Scientific reports. 2022 04; 12(1):5503. doi: 10.1038/s41598-022-09505-1. [PMID: 35365736]
  • Mladena Glavaš, Agata Gitlin-Domagalska, Dawid Dębowski, Natalia Ptaszyńska, Anna Łęgowska, Krzysztof Rolka. Vasopressin and Its Analogues: From Natural Hormones to Multitasking Peptides. International journal of molecular sciences. 2022 Mar; 23(6):. doi: 10.3390/ijms23063068. [PMID: 35328489]
  • Paul J Gow, Marie Sinclair, Phoebe A Thwaites, Peter W Angus, Brooke Chapman, Ryma Terbah, Adam G Testro. Safety and efficacy of outpatient continuous terlipressin infusion for the treatment of portal hypertensive complications in cirrhosis. European journal of gastroenterology & hepatology. 2022 02; 34(2):206-212. doi: 10.1097/meg.0000000000001950. [PMID: 32976193]
  • Shengtao Lin, Da Dorothy Zhang, Yuan Gao, Yueke Zhu, Bing Hou. Letter to Editor: The Synergistic Effect of Albumin on Terlipressin in Acute-on-Chronic Liver Failure With Acute Kidney Injury. Hepatology (Baltimore, Md.). 2019 04; 69(4):1845. doi: 10.1002/hep.30539. [PMID: 30706495]
  • P Karaaslan, S Sevmis. Effect of terlipressin infusion therapy on recipient's hepatic and renal functions in living donor liver transplantations: Experience from a tertiary hospital. Nigerian journal of clinical practice. 2019 Feb; 22(2):265-269. doi: 10.4103/njcp.njcp_268_17. [PMID: 30729953]
  • Abhinav Anand, Shalimar. Is Terlipressin Superior to Noradrenaline in the Treatment of Acute Kidney Injury in Acute-on-Chronic Liver Failure?. Hepatology (Baltimore, Md.). 2019 01; 69(1):463-464. doi: 10.1002/hep.30299. [PMID: 30281816]
  • Sapana Verma, Shaleen Agarwal, Shweta Singh, Nivedita Pandey, Subhash Gupta. Letter To Editor: Terlipressin is Superior to Noradrenaline in the Management of Acute Kidney Injury in Acute On Chronic Liver Failure. Hepatology (Baltimore, Md.). 2018 12; 68(6):2442-2443. doi: 10.1002/hep.30269. [PMID: 30216483]
  • Lotte Borg Lange, Kristine Borg. [Severe reversible penile ischaemia after terlipressin treatment of hepatorenal syndrome]. Ugeskrift for laeger. 2018 Oct; 180(43):. doi: NULL. [PMID: 30375954]
  • Wanqi Tang, Xiaoyuan Ma, Wei Ma, Xue Yang, Yuhao Yi, Li Luo, Jun Yan, Huaping Liang. [Effects of terlipressin on blood pressure and survival in septic mice following trauma and its mechanism]. Zhonghua wei zhong bing ji jiu yi xue. 2018 Jul; 30(7):619-624. doi: 10.3760/cma.j.issn.2095-4352.2018.07.001. [PMID: 30045786]
  • Qun-Qun Jiang, Mei-Fang Han, Ke Ma, Guang Chen, Xiao-Yang Wan, Semvua Bukheti Kilonzo, Wen-Yu Wu, Yong-Li Wang, Jie You, Qin Ning. Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis. World journal of gastroenterology. 2018 Jun; 24(21):2300-2310. doi: 10.3748/wjg.v24.i21.2300. [PMID: 29881239]
  • Georgios N Kalambokis, Ilias Tsiakas, Maria Christaki, Christina Koustousi, Leonidas Christou, Gerasimos Baltayiannis, Dimitrios Christodoulou. Systemic hemodynamic response to terlipressin predicts development of hepatorenal syndrome and survival in advanced cirrhosis. European journal of gastroenterology & hepatology. 2018 06; 30(6):659-667. doi: 10.1097/meg.0000000000001088. [PMID: 29432366]
  • Haiqing Wang, Aixiang Liu, Wentao Bo, Xielin Feng, Yong Hu. Terlipressin in the treatment of hepatorenal syndrome: A systematic review and meta-analysis. Medicine. 2018 Apr; 97(16):e0431. doi: 10.1097/md.0000000000010431. [PMID: 29668606]
  • Salvatore Piano, Marta Tonon, Paolo Angeli. Management of ascites and hepatorenal syndrome. Hepatology international. 2018 Feb; 12(Suppl 1):122-134. doi: 10.1007/s12072-017-9815-0. [PMID: 28836115]
  • Isabelle Colle, Pierre-François Laterre. Hepatorenal syndrome: the clinical impact of vasoactive therapy. Expert review of gastroenterology & hepatology. 2018 Feb; 12(2):173-188. doi: 10.1080/17474124.2018.1417034. [PMID: 29258378]
  • François Durand, Jody C Olson, Mitra K Nadim. Renal dysfunction and cirrhosis. Current opinion in critical care. 2017 Dec; 23(6):457-462. doi: 10.1097/mcc.0000000000000457. [PMID: 29023314]
  • Ji-Na Zheng, Yi-Jing Han, Tian-Tian Zou, Yu-Jie Zhou, Dan-Qin Sun, Jian-Hong Zhong, Martin Braddock, Ming-Hua Zheng. Comparative efficacy of vasoconstrictor therapies for type 1 hepatorenal syndrome: a network meta-analysis. Expert review of gastroenterology & hepatology. 2017 Nov; 11(11):1009-1018. doi: 10.1080/17474124.2017.1356223. [PMID: 28708431]
  • Tom Florian Ulmer, Anne Weiland, Georg Lurje, Christian Klink, Anne Andert, Hamid Alizai, Christoph Heidenhain, Ulf Neumann. Comparative study of the effects of terlipressin versus splenectomy on liver regeneration after partial hepatectomy in rats. Hepatobiliary & pancreatic diseases international : HBPD INT. 2017 Oct; 16(5):506-511. doi: 10.1016/s1499-3872(17)60036-5. [PMID: 28992883]
  • Mettu Srinivas Reddy, Ilankumaran Kaliamoorthy, Akila Rajakumar, Selvakumar Malleeshwaran, Ellango Appuswamy, Sukanya Lakshmi, Joy Varghese, Mohamed Rela. Double-blind randomized controlled trial of the routine perioperative use of terlipressin in adult living donor liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2017 08; 23(8):1007-1014. doi: 10.1002/lt.24759. [PMID: 28294557]
  • Mohamed A Kandil, Khalid M Abouelenain, Ayman Alsebaey, Hanaa S Rashed, Mohamed H Afifi, Mohamed A Mahmoud, Khaled A Yassen. Impact of terlipressin infusion during and after live donor liver transplantation on incidence of acute kidney injury and neutrophil gelatinase-associated lipocalin serum levels: A randomized controlled trial. Clinical transplantation. 2017 08; 31(8):. doi: 10.1111/ctr.13019. [PMID: 28564127]
  • Ladan Golestaneh, Joel Neugarten. Dual Organ Duel: The Hepatorenal Axis. Advances in chronic kidney disease. 2017 07; 24(4):253-260. doi: 10.1053/j.ackd.2017.05.009. [PMID: 28778366]
  • F J Gifford, J R Morling, J A Fallowfield. Systematic review with meta-analysis: vasoactive drugs for the treatment of hepatorenal syndrome type 1. Alimentary pharmacology & therapeutics. 2017 03; 45(5):593-603. doi: 10.1111/apt.13912. [PMID: 28052382]
  • Zhi Chen, Ping Zhou, Yuanhua Lu, Chunli Yang. [Comparison of effect of norepinephrine and terlipressin on patients with ARDS combined with septic shock: a prospective single-blind randomized controlled trial]. Zhonghua wei zhong bing ji jiu yi xue. 2017 Feb; 29(2):111-116. doi: 10.3760/cma.j.issn.2095-4352.2017.02.004. [PMID: 28625256]
  • Florence Wong, Stephen Chris Pappas, Thomas D Boyer, Arun J Sanyal, Jasmohan S Bajaj, Shannon Escalante, Khurram Jamil. Terlipressin Improves Renal Function and Reverses Hepatorenal Syndrome in Patients With Systemic Inflammatory Response Syndrome. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2017 02; 15(2):266-272.e1. doi: 10.1016/j.cgh.2016.07.016. [PMID: 27464593]
  • Kei Taniguchi, Yoshifuru Tamura, Takanori Kumagai, Shigeru Shibata, Shunya Uchida. Stimulation of V1a receptor increases renal uric acid clearance via urate transporters: insight into pathogenesis of hypouricemia in SIADH. Clinical and experimental nephrology. 2016 Dec; 20(6):845-852. doi: 10.1007/s10157-016-1248-x. [PMID: 26935049]
  • So Mi Kim, Il Han Song. [Acute Kidney Injury in Cirrhotic Patients with Portal Hypertension]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2016 Nov; 68(5):237-244. doi: 10.4166/kjg.2016.68.5.237. [PMID: 27871159]
  • Tsung-Hsing Hung, Chen-Chi Tsai, Chih-Wei Tseng, Kuo-Chih Tseng, Yu-Hsi Hsieh, Chih-Chun Tsai. No difference in mortality between terlipressin and somatostatin treatments in cirrhotic patients with esophageal variceal bleeding and renal functional impairment. European journal of gastroenterology & hepatology. 2016 Nov; 28(11):1275-9. doi: 10.1097/meg.0000000000000703. [PMID: 27455080]
  • Gaetano Bertino, Graziella Privitera, Francesco Purrello, Shirin Demma, Emanuele Crisafulli, Luisa Spadaro, Nikolaos Koukias, Emmanuel A Tsochatzis. Emerging hepatic syndromes: pathophysiology, diagnosis and treatment. Internal and emergency medicine. 2016 Oct; 11(7):905-16. doi: 10.1007/s11739-016-1478-7. [PMID: 27273018]
  • Florence Wong. Diagnosing and treating renal disease in cirrhotic patients. Minerva gastroenterologica e dietologica. 2016 Sep; 62(3):253-66. doi: . [PMID: 27096702]
  • Ángelo Zambam de Mattos, Angelo Alves de Mattos, Nahum Méndez-Sánchez. Hepatorenal syndrome: Current concepts related to diagnosis and management. Annals of hepatology. 2016 Jul; 15(4):474-81. doi: NULL. [PMID: 27236146]
  • Tary A Salman, Ahmed M Edrees, Hala H El-Said, Osama L El-Abd, Gasser I El-Azab. Effect of different therapeutic modalities on systemic, renal, and hepatic hemodynamics and short-term outcomes in cirrhotic patients with spontaneous bacterial peritonitis. European journal of gastroenterology & hepatology. 2016 Jul; 28(7):777-85. doi: 10.1097/meg.0000000000000635. [PMID: 27097354]
  • Thomas D Boyer, Arun J Sanyal, Florence Wong, R Todd Frederick, John R Lake, Jacqueline G O'Leary, Daniel Ganger, Khurram Jamil, Stephen Chris Pappas. Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1. Gastroenterology. 2016 Jun; 150(7):1579-1589.e2. doi: 10.1053/j.gastro.2016.02.026. [PMID: 26896734]
  • K Lenz, R Buder, G Lohr, P Piringer, M Voglmayr. [Hepatorenal syndrome in decompensated cirrhosis : A special form of acute renal failure]. Medizinische Klinik, Intensivmedizin und Notfallmedizin. 2016 Jun; 111(5):440-6. doi: 10.1007/s00063-016-0177-5. [PMID: 27241778]
  • Marta Cavallin, Salvatore Piano, Antonietta Romano, Silvano Fasolato, Anna Chiara Frigo, Gianpiero Benetti, Elisabetta Gola, Filippo Morando, Marialuisa Stanco, Silvia Rosi, Antonietta Sticca, Umberto Cillo, Paolo Angeli. Terlipressin given by continuous intravenous infusion versus intravenous boluses in the treatment of hepatorenal syndrome: A randomized controlled study. Hepatology (Baltimore, Md.). 2016 Mar; 63(3):983-92. doi: 10.1002/hep.28396. [PMID: 26659927]
  • Ankur Jindal, Ajeet S Bhadoria, Rakhi Maiwall, Shiv K Sarin. Evaluation of acute kidney injury and its response to terlipressin in patients with acute-on-chronic liver failure. Liver international : official journal of the International Association for the Study of the Liver. 2016 Jan; 36(1):59-67. doi: 10.1111/liv.12895. [PMID: 26081914]
  • Xudong Xiao, Jie Zhang, Yaoli Wang, Jian Zhou, Yu Zhu, Dongpo Jiang, Liangming Liu, Tao Li. Effects of terlipressin on patients with sepsis via improving tissue blood flow. The Journal of surgical research. 2016 Jan; 200(1):274-82. doi: 10.1016/j.jss.2015.07.016. [PMID: 26253455]
  • Martin Janicko, Eduard Veseliny, Gabriela Senajova, Peter Jarcuska. Predictors of hepatorenal syndrome in alcoholic liver cirrhosis. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 2015 Dec; 159(4):661-5. doi: 10.5507/bp.2015.010. [PMID: 25820623]
  • Ezequiel Rodriguez, Gustavo Henrique Pereira, Elsa Solà, Chiara Elia, Rogelio Barreto, Elisa Pose, Jordi Colmenero, Javier Fernandez, Miquel Navasa, Vicente Arroyo, Pere Ginès. Treatment of type 2 hepatorenal syndrome in patients awaiting transplantation: Effects on kidney function and transplantation outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2015 Nov; 21(11):1347-54. doi: 10.1002/lt.24210. [PMID: 26178066]
  • Sun Young Yim, Yeon Seok Seo, Chang Ho Jung, Tae Hyung Kim, Eun Sun Kim, Bora Keum, Ji Hoon Kim, Hyonggin An, Hyung Joon Yim, Jong Eun Yeon, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Kwan Soo Byun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu. Risk Factors for Developing Hyponatremia During Terlipressin Treatment: A Retrospective Analyses in Variceal Bleeding. Journal of clinical gastroenterology. 2015 Aug; 49(7):607-12. doi: 10.1097/mcg.0000000000000217. [PMID: 25216384]
  • Marta Cavallin, Patrick S Kamath, Manuela Merli, Silvano Fasolato, Pierluigi Toniutto, Francesco Salerno, Mauro Bernardi, Roberto Giulio Romanelli, Cosimo Colletta, Freddy Salinas, Antonio Di Giacomo, Lorenzo Ridola, Ezio Fornasiere, Paolo Caraceni, Filippo Morando, Salvatore Piano, Angelo Gatta, Paolo Angeli. Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial. Hepatology (Baltimore, Md.). 2015 Aug; 62(2):567-74. doi: 10.1002/hep.27709. [PMID: 25644760]
  • Vladimír Hrabovský, Alice Mendlová, Terezie Vavříčková. [Hepatorenal syndrome - pathophysiology, diagnosis and treatment]. Vnitrni lekarstvi. 2015 Jul; 61(7-8):649-54. doi: NULL. [PMID: 26375691]
  • Y J Won, H J Kim, B G Lim, H S Ahn, M H Hwang, I O Lee. Effect of Perioperative Terlipressin on Postoperative Renal Function in Patients Who Have Undergone Living Donor Liver Transplantation: A Meta-Analysis of Randomized Controlled Trials. Transplantation proceedings. 2015 Jul; 47(6):1917-25. doi: 10.1016/j.transproceed.2015.06.023. [PMID: 26293074]
  • Chiara Elia, Elsa Solà Vergés, Ezequiel Rodríguez, Pere Ginès. Transient increase in urine protein excretion during treatment with terlipressin and albumin for type-1 hepatorenal syndrome. Journal of hepatology. 2015 Feb; 62(2):493-5. doi: 10.1016/j.jhep.2014.09.030. [PMID: 25283143]
  • Mads Egerod Israelsen, Lise Lotte Gluud, Aleksander Krag. Acute kidney injury and hepatorenal syndrome in cirrhosis. Journal of gastroenterology and hepatology. 2015 Feb; 30(2):236-43. doi: 10.1111/jgh.12709. [PMID: 25160511]
  • Antoine G Schneider, Anthony Schelleman, Mark D Goodwin, Michael Bailey, Glenn M Eastwood, Rinaldo Bellomo. Contrast-enhanced ultrasound evaluation of the renal microcirculation response to terlipressin in hepato-renal syndrome: a preliminary report. Renal failure. 2015 Feb; 37(1):175-9. doi: 10.3109/0886022x.2014.977140. [PMID: 25365636]
  • Justin M Belcher, Steven G Coca, Chirag R Parikh. Creatinine Change on Vasoconstrictors as Mortality Surrogate in Hepatorenal Syndrome: Systematic Review & Meta-Analysis. PloS one. 2015; 10(8):e0135625. doi: 10.1371/journal.pone.0135625. [PMID: 26295585]
  • Marc Nguyen-Tat, Esther Götz, Peter Scholz-Kreisel, Juliane Ahrens, Visvakanth Sivanathan, Jörn Schattenberg, Johannes W Rey, Marcus-Alexander Wörns, Peter R Galle, Jens U Marquardt. [Response to Terlipressin and albumin is associated with improved outcome in patients with cirrhosis and hepatorenal syndrome]. Deutsche medizinische Wochenschrift (1946). 2015 Jan; 140(2):e21-6. doi: 10.1055/s-0040-100444. [PMID: 25612289]
  • Ahmed Mukhtar, Ihab Mahmoud, Gihan Obayah, Ahmed Hasanin, Fawzia Aboul-Fetouh, Hany Dabous, Mohamed Bahaa, Amr Abdelaal, Mohamed Fathy, Mahmoud El Meteini. Intraoperative terlipressin therapy reduces the incidence of postoperative acute kidney injury after living donor liver transplantation. Journal of cardiothoracic and vascular anesthesia. 2015; 29(3):678-83. doi: 10.1053/j.jvca.2014.10.008. [PMID: 25620766]
  • A V Kutina, A S Marina, Yu V Natochin. The involvement of V1b-subtype vasopressin receptors in regulation of potassium ions excretion in the rat kidneys. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 2014 Nov; 459(?):338-40. doi: 10.1134/s001249661406009x. [PMID: 25560210]
  • Claire Francoz, François Durand. Type-1 hepatorenal syndrome in patients with cirrhosis and infection vs. sepsis-induced acute kidney injury: what matters?. Journal of hepatology. 2014 May; 60(5):907-9. doi: 10.1016/j.jhep.2014.02.001. [PMID: 24508549]
  • Ezequiel Rodríguez, Chiara Elia, Elsa Solà, Rogelio Barreto, Isabel Graupera, Alida Andrealli, Gustavo Pereira, Maria Poca, Jordi Sánchez, Mónica Guevara, Germán Soriano, Carlo Alessandria, Javier Fernández, Vicente Arroyo, Pere Ginès. Terlipressin and albumin for type-1 hepatorenal syndrome associated with sepsis. Journal of hepatology. 2014 May; 60(5):955-61. doi: 10.1016/j.jhep.2013.12.032. [PMID: 24447876]
  • Shiqian Wan, Xuefa Wan, Qingjing Zhu, Jianxin Peng. [A comparative study of high-or low-dose terlipressin therapy in patients with cirrhosis and type 1 hepatorenal syndrome]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2014 May; 22(5):349-53. doi: 10.3760/cma.j.issn.1007-3418.2014.05.006. [PMID: 25180869]
  • Fa-Yauh Lee, Sun-Sang Wang, Ming-Hung Tsai, Hui-Chun Huang, Han-Chieh Lin, Shou-Dong Lee. Adrenal dysfunction in portal hypertensive rats with acute hemorrhage. PloS one. 2014; 9(3):e92093. doi: 10.1371/journal.pone.0092093. [PMID: 24633079]
  • Chien-Chang Lee, Meng-Tse Gabriel Lee, Shy-Shin Chang, Si-Huei Lee, Yu-Chi Huang, Chia-Hung Yo, Shih-Hao Lee, Shyr-Chyr Chen. A comparison of vasopressin, terlipressin, and lactated ringers for resuscitation of uncontrolled hemorrhagic shock in an animal model. PloS one. 2014; 9(4):e95821. doi: 10.1371/journal.pone.0095821. [PMID: 24759799]
  • Yao-Kuang Wang, Daw-Yang Hwang, Sophie S W Wang, Shang-Jyh Hwang, Li-Tzong Chen, Mei-Chuan Kuo. Terlipressin-induced hyponatremic encephalopathy in a noncirrhotic patient. The Kaohsiung journal of medical sciences. 2013 Dec; 29(12):691-4. doi: 10.1016/j.kjms.2013.08.003. [PMID: 24296059]
  • Saubhik Ghosh, Narendra S Choudhary, Arun K Sharma, Baljinder Singh, Pradeep Kumar, Ritesh Agarwal, Navneet Sharma, Ashish Bhalla, Yogesh K Chawla, Virendra Singh. Noradrenaline vs terlipressin in the treatment of type 2 hepatorenal syndrome: a randomized pilot study. Liver international : official journal of the International Association for the Study of the Liver. 2013 Sep; 33(8):1187-93. doi: 10.1111/liv.12179. [PMID: 23601499]
  • Chao Ding, Xingjiang Wu, Xinxin Fan, Changsheng He, Jieshou Li. Hemodynamic effects of continuous versus bolus infusion of terlipressin for portal hypertension: a randomized comparison. Journal of gastroenterology and hepatology. 2013 Jul; 28(7):1242-6. doi: 10.1111/jgh.12195. [PMID: 23489113]
  • Elsa Solà, Andrés Cárdenas, Pere Ginès. Results of pretransplant treatment of hepatorenal syndrome with terlipressin. Current opinion in organ transplantation. 2013 Jun; 18(3):265-70. doi: 10.1097/mot.0b013e3283614c7a. [PMID: 23652609]
  • Heon Ju Lee, Myung Jin Oh. A case of peripheral gangrene and osteomyelitis secondary to terlipressin therapy in advanced liver disease. Clinical and molecular hepatology. 2013 Jun; 19(2):179-84. doi: 10.3350/cmh.2013.19.2.179. [PMID: 23837143]
  • Mads Egerod Israelsen, Lise Lotte Gluud, Flemming Bendtsen, Søren Møller, Aleksander Ahm Krag. [Hepatorenal syndrome: diagnosis, treatment and prevention]. Ugeskrift for laeger. 2013 May; 175(22):1562-6. doi: NULL. [PMID: 23721840]
  • Binoy Shivanna, Danielle Rios, Joseph Rossano, Caraciolo J Fernandes, Mohan Pammi. Vasopressin and its analogues for the treatment of refractory hypotension in neonates. The Cochrane database of systematic reviews. 2013 Mar; ?(3):CD009171. doi: 10.1002/14651858.cd009171.pub2. [PMID: 23543571]
  • E Prakoso, C Jones, D J Koorey, S I Strasser, D Bowen, G W McCaughan, N A Shackel. Terlipressin therapy for moderate-to-severe hyponatraemia in patients with liver failure. Internal medicine journal. 2013 Mar; 43(3):240-6. doi: 10.1111/imj.12032. [PMID: 23176166]
  • Feng Hua, Xiang Wang, Lei Zhu. Terlipressin decreases vascular endothelial growth factor expression and improves oxygenation in patients with acute respiratory distress syndrome and shock. The Journal of emergency medicine. 2013 Feb; 44(2):434-9. doi: 10.1016/j.jemermed.2012.02.073. [PMID: 22921855]
  • Matthias Hinz, Alexander Wree, Christoph Jochum, Lars P Bechmann, Fuat Saner, Alexander L Gerbes, Guido Gerken, Ali Canbay. High age and low sodium urine concentration are associated with poor survival in patients with hepatorenal syndrome. Annals of hepatology. 2013 Jan; 12(1):92-9. doi: 10.1016/s1665-2681(19)31390-0. [PMID: 23293199]
  • Andrew Davenport. AKI in a patient with cirrhosis and ascites. Clinical journal of the American Society of Nephrology : CJASN. 2012 Dec; 7(12):2041-8. doi: 10.2215/cjn.03390412. [PMID: 22977213]
  • Vladimír Hrabovský, Alice Mendlová, Zdeněk Zadák, Vladimír Bláha, Radomír Hyšpler, Alena Tichá, Zdeněk Svagera. Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations. Wiener klinische Wochenschrift. 2012 Dec; 124(23-24):815-21. doi: 10.1007/s00508-012-0292-0. [PMID: 23179434]
  • Paolo Angeli, Pere Gines. Hepatorenal syndrome, MELD score and liver transplantation: an evolving issue with relevant implications for clinical practice. Journal of hepatology. 2012 Nov; 57(5):1135-40. doi: 10.1016/j.jhep.2012.06.024. [PMID: 22749942]
  • Ornella Piazza, Giuliana Scarpati, Fabio Rispoli, Michele Iannuzzi, Rosalba Tufano, Edoardo De Robertis. Terlipressin in brain-death donors. Clinical transplantation. 2012 Nov; 26(6):E571-5. doi: 10.1111/ctr.12038. [PMID: 23121213]
  • J Pascual-Ramírez, M Aguirre Sánchez-Covisa, F Araujo, S Gil Trujillo, L G Collar, S Bocharán. [Septic shock. Update of treatment using hypertonic saline and antidiuretic hormone-vasopressin]. Revista espanola de anestesiologia y reanimacion. 2012 Aug; 59(7):370-8. doi: 10.1016/j.redar.2012.05.037. [PMID: 22770759]
  • Virendra Singh, Souvik Ghosh, Baljinder Singh, Pradeep Kumar, Navneet Sharma, Ashish Bhalla, A K Sharma, N S Choudhary, Yogesh Chawla, C K Nain. Noradrenaline vs. terlipressin in the treatment of hepatorenal syndrome: a randomized study. Journal of hepatology. 2012 Jun; 56(6):1293-8. doi: 10.1016/j.jhep.2012.01.012. [PMID: 22322237]
  • Cláudia Fagundes, Pere Ginès. Hepatorenal syndrome: a severe, but treatable, cause of kidney failure in cirrhosis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012 Jun; 59(6):874-85. doi: 10.1053/j.ajkd.2011.12.032. [PMID: 22480795]
  • Florence Wong. Recent advances in our understanding of hepatorenal syndrome. Nature reviews. Gastroenterology & hepatology. 2012 May; 9(7):382-91. doi: 10.1038/nrgastro.2012.96. [PMID: 22614754]
  • Yoshiyuki Narahara, Hidenori Kanazawa, Choitsu Sakamoto, Hitoshi Maruyama, Osamu Yokosuka, Satoshi Mochida, Masahito Uemura, Hiroshi Fukui, Yasukiyo Sumino, Yasushi Matsuzaki, Naohiko Masaki, Shigehiro Kokubu, Kiwamu Okita. The efficacy and safety of terlipressin and albumin in patients with type 1 hepatorenal syndrome: a multicenter, open-label, explorative study. Journal of gastroenterology. 2012 Mar; 47(3):313-20. doi: 10.1007/s00535-011-0485-8. [PMID: 22038555]
  • Y-Y Huang, J-Y Sun, J-Y Wang, C-X Bai, B-M He. Terlipressin resolves ascites of cirrhotic rats through downregulation of aquaporin 2. The Journal of international medical research. 2012; 40(5):1735-44. doi: 10.1177/030006051204000512. [PMID: 23206455]
  • S H Hong, J M Lee, J H Choi, H S Chung, J H Park, C S Park. Perioperative assessment of terlipressin infusion during living donor liver transplantation. The Journal of international medical research. 2012; 40(1):225-36. doi: 10.1177/147323001204000123. [PMID: 22429362]
  • Søren Møller, Niels Kristian Aagaard, Lars Schmidt, Henning Grønbaek, Jesper Bach Hansen, Flemming Bendtsen. Treatment of the hepatorenal syndrome and hyponatremia in cirrhosis - part II. Danish medical journal. 2012 Jan; 59(1):C4372. doi: NULL. [PMID: 22239848]
  • Ken Ishikawa, Li Wan, Paolo Calzavacca, Rinaldo Bellomo, Michael Bailey, Clive N May. The effects of terlipressin on regional hemodynamics and kidney function in experimental hyperdynamic sepsis. PloS one. 2012; 7(2):e29693. doi: 10.1371/journal.pone.0029693. [PMID: 22355305]
  • Basilio Fimiani, Domenico Della Guardia, Claudio Puoti, Giuseppe D'Adamo, Olimpia Cioffi, Anna Pagano, Maria Rosaria Tagliamonte, Antonio Izzi. The use of terlipressin in cirrhotic patients with refractory ascites and normal renal function: a multicentric study. European journal of internal medicine. 2011 Dec; 22(6):587-90. doi: 10.1016/j.ejim.2011.06.013. [PMID: 22075285]
  • Agata Furgala, Piotr J Thor, Daisy-Scarlett Maccallum, Lukasz Dobrek, Andrzej Matyja. Terlipressin facilitates gastric and autonomic system dysfunctions in liver cirrhosis. Hepato-gastroenterology. 2011 Nov; 58(112):2041-4. doi: 10.5754/hge10163. [PMID: 22234076]
  • Brijesh Srivastava, Graeme J M Alexander. Renal failure in chronic liver disease and the hepatorenal syndrome. British journal of hospital medicine (London, England : 2005). 2011 Sep; 72(9):497-503. doi: 10.12968/hmed.2011.72.9.497. [PMID: 22041830]
  • Salvatore Piano, Filippo Morando, Silvano Fasolato, Marta Cavallin, Novella Boscato, Patrizia Boccagni, Giacomo Zanus, Umberto Cillo, Angelo Gatta, Paolo Angeli. Continuous recurrence of type 1 hepatorenal syndrome and long-term treatment with terlipressin and albumin: a new exception to MELD score in the allocation system to liver transplantation?. Journal of hepatology. 2011 Aug; 55(2):491-6. doi: 10.1016/j.jhep.2011.02.002. [PMID: 21334405]
  • Thomas D Boyer, Arun J Sanyal, Guadalupe Garcia-Tsao, Andres Blei, Daniel Carl, Alice S Bexon, Peter Teuber. Predictors of response to terlipressin plus albumin in hepatorenal syndrome (HRS) type 1: relationship of serum creatinine to hemodynamics. Journal of hepatology. 2011 Aug; 55(2):315-21. doi: 10.1016/j.jhep.2010.11.020. [PMID: 21167235]
  • Ahmed Mukhtar, Maged Salah, Fawzia Aboulfetouh, Gihan Obayah, Maha Samy, Azza Hassanien, Mohamed Bahaa, Amr Abdelaal, Mohamed Fathy, Hany Saeed, Mohamed Rady, Ibrahim Mostafa, Mahmoud El-Meteini. The use of terlipressin during living donor liver transplantation: Effects on systemic and splanchnic hemodynamics and renal function. Critical care medicine. 2011 Jun; 39(6):1329-34. doi: 10.1097/ccm.0b013e3182120842. [PMID: 21336108]
  • Mihai Oltean, Gustaf Herlenius. Renal protection during liver transplantation: an ounce of prevention is worth a pound of cure. Critical care medicine. 2011 Jun; 39(6):1564-5. doi: 10.1097/ccm.0b013e318215bb31. [PMID: 21610624]
  • Matthias Lange, Christian Ertmer, Sebastian Rehberg, Andrea Morelli, Gabriele Köhler, Tim G Kampmeier, Hugo Van Aken, Martin Westphal. Effects of two different dosing regimens of terlipressin on organ functions in ovine endotoxemia. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2011 May; 60(5):429-37. doi: 10.1007/s00011-010-0299-9. [PMID: 21190124]
  • M Lehmann, T Bruns, A Herrmann, M Fritzenwanger, A Stallmach. [54-year-old male with hepatic cirrhosis and therapy-associated torsade de pointes tachycardia]. Der Internist. 2011 Apr; 52(4):445-8, 450. doi: 10.1007/s00108-010-2667-5. [PMID: 20938628]
  • Aleksander Krag, Erling B Pedersen, Søren Møller, Flemming Bendtsen. Effects of the vasopressin agonist terlipressin on plasma cAMP and ENaC excretion in the urine in patients with cirrhosis and water retention. Scandinavian journal of clinical and laboratory investigation. 2011 Apr; 71(2):112-6. doi: 10.3109/00365513.2010.537369. [PMID: 21080762]
  • Sascha Meyer, William McGuire, Sven Gottschling, Ghiath Mohammed Shamdeen, Ludwig Gortner. The role of vasopressin and terlipressin in catecholamine-resistant shock and cardio-circulatory arrest in children: review of the literature. Wiener medizinische Wochenschrift (1946). 2011 Apr; 161(7-8):192-203. doi: 10.1007/s10354-010-0853-7. [PMID: 21253815]
  • Mirela Dobre, Sevag Demirjian, Ashwini R Sehgal, Sankar D Navaneethan. Terlipressin in hepatorenal syndrome: a systematic review and meta-analysis. International urology and nephrology. 2011 Mar; 43(1):175-84. doi: 10.1007/s11255-010-9725-8. [PMID: 20306131]
  • Elif Ari, Yusuf Yilmaz, Alla Elden Kedrah, Yesim Alahdab, Fulya Cakalagaoglu, Hakki Arikan, Hüseyin Kocak, Beyza Macunluoglu, Aydin Atakan, Arzu Kahveci, Ebru Asicioglu, Serhan Tuglular, Cetin Ozener. Protective effect of the vasopressin agonist terlipressin in a rat model of contrast-induced nephropathy. American journal of nephrology. 2011; 33(3):269-76. doi: 10.1159/000324764. [PMID: 21372562]
  • Harshal Rajekar, Yogesh Chawla. Terlipressin in hepatorenal syndrome: Evidence for present indications. Journal of gastroenterology and hepatology. 2011 Jan; 26 Suppl 1(?):109-14. doi: 10.1111/j.1440-1746.2010.06583.x. [PMID: 21199521]
  • David D Bañuelos Ramírez, Silvia Sánchez Alonso, María Magdalena Ramírez Palma. Sildenafil in severe peripheral ischemia induced by terlipressin. A case report. Reumatologia clinica. 2011 Jan; 7(1):59-60. doi: 10.1016/j.reuma.2010.05.005. [PMID: 21794781]
  • Ahmed A Magan, Atif A Khalil, Mohamed H Ahmed. Terlipressin and hepatorenal syndrome: what is important for nephrologists and hepatologists. World journal of gastroenterology. 2010 Nov; 16(41):5139-47. doi: 10.3748/wjg.v16.i41.5139. [PMID: 21049548]
  • Elsa Solà, Sabela Lens, Mónica Guevara, Marta Martín-Llahí, Claudia Fagundes, Gustavo Pereira, Marco Pavesi, Javier Fernández, Juan González-Abraldes, Angels Escorsell, Antoni Mas, Jaume Bosch, Vicente Arroyo, Pere Ginès. Hyponatremia in patients treated with terlipressin for severe gastrointestinal bleeding due to portal hypertension. Hepatology (Baltimore, Md.). 2010 Nov; 52(5):1783-90. doi: 10.1002/hep.23893. [PMID: 20931555]
  • J M King, S D Bradshaw. Stress in an Island kangaroo? The Barrow Island euro, Macropus robustus isabellinus. General and comparative endocrinology. 2010 May; 167(1):60-7. doi: 10.1016/j.ygcen.2010.02.018. [PMID: 20178800]
  • Sashidhar V Sagi, Sahil Mittal, Krishna S Kasturi, Gagan K Sood. Terlipressin therapy for reversal of type 1 hepatorenal syndrome: a meta-analysis of randomized controlled trials. Journal of gastroenterology and hepatology. 2010 May; 25(5):880-5. doi: 10.1111/j.1440-1746.2009.06132.x. [PMID: 20074149]
  • Christos K Triantos, Dimitrios Samonakis, Ulrich Thalheimer, Evangelos Cholongitas, Marco Senzolo, Laura Marelli, Gioacchino Leandro, David Patch, Andrew K Burroughs. Terlipressin therapy for renal failure in cirrhosis. European journal of gastroenterology & hepatology. 2010 Apr; 22(4):481-6. doi: 10.1097/meg.0b013e3283345524. [PMID: 19952764]
  • Jong Jin Hyun, Yeon Seok Seo, Kwang Gyun Lee, Bora Keum, Hyung Joon Yim, Yoon Tae Jeen, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu. Terlipressin-induced hyponatremic seizure. Scandinavian journal of gastroenterology. 2010 Apr; 45(4):501-4. doi: 10.3109/00365520903477355. [PMID: 20302535]