Potassium bromate(V) (KBrO3) (BioDeep_00000014912)
Secondary id: BioDeep_00001867754
human metabolite
代谢物信息卡片
Potassium bromic acid(V) (kbro3)
化学式: BrKO3 (165.86678899999998)
中文名称: 溴分析滴定液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [K+].[O-][Br](=O)=O
InChI: /q
描述信息
Dough conditioning agent used in bread making. Normally decomposed during the baking process; also used in barley malting
D000074385 - Food Ingredients > D005503 - Food Additives
D009676 - Noxae > D002273 - Carcinogens
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:38211
- KEGG: C19295
- PubChem: 23673461
- PubChem: 24444
- HMDB: HMDB0303536
- ChEMBL: CHEMBL2311074
- foodb: FDB015414
- chemspider: 22852
- CAS: 7758-01-2
- PubChem: 124489967
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Abeer A Mahmoud, Maha Zayed Mohamed, Ebtehal Z Hassen. Protective effects of Urtica dioica on the cerebral cortex damage induced by Potassium bromate in adult male albino rats.
Ultrastructural pathology.
2024 Mar; 48(2):81-93. doi:
10.1080/01913123.2023.2287664. [PMID: 38017656] - H Turan Akkoyun, Ahmet Uyar, Mahire Bayramoglu Akkoyun, Aydın Şükrü Bengü, Şule Melek, Fatma Karagözoğlu, Sevinç Aydın, Suat Ekin, Sinem Aslan Erdem. The protective effect of arbutin against potassium bromate-induced oxidative damage in the rat brain.
Journal of biochemical and molecular toxicology.
2023 Feb; 37(2):e23248. doi:
10.1002/jbt.23248. [PMID: 36284482] - Amr S Osman, Sally E Abu-Risha, Samaa M Bakr, Ahmed E Altyar, Eman Fayad, Mamdouh R El-Sawi, Wafaa M El-Kholy. Comparative study between effects of ginkgo biloba extract and extract loaded on gold nanoparticles on hepatotoxicity induced by potassium bromate.
Environmental science and pollution research international.
2023 Jan; 30(2):5027-5036. doi:
10.1007/s11356-022-22324-1. [PMID: 35978237] - Ali Abdullah Al-Mareed, Mohammed Abul Farah, Khalid Mashay Al-Anazi, Waleed A Q Hailan, M Ajmal Ali. Potassium bromate-induced oxidative stress, genotoxicity and cytotoxicity in the blood and liver cells of mice.
Mutation research. Genetic toxicology and environmental mutagenesis.
2022 Jun; 878(?):503481. doi:
10.1016/j.mrgentox.2022.503481. [PMID: 35649675] - Raouia Dhouibi, Hanen Affes, Maryem Ben Salem, Slim Charfi, Rim Marekchi, Serria Hammami, Khaled Zeghal, Kamilia Ksouda. Protective effect of Urtica dioica in induced neurobehavioral changes, nephrotoxicity and hepatotoxicity after chronic exposure to potassium bromate in rats.
Environmental pollution (Barking, Essex : 1987).
2021 Oct; 287(?):117657. doi:
10.1016/j.envpol.2021.117657. [PMID: 34435563] - Adeola Temitope Salami, Gloria Enevwo Okotie, Precious Nekachi Echendu, Uwaifoh Akpamu, Samuel Babafemi Olaleye. Potassium bromate (KBrO3) modulates oxidative stress and inflammatory biomarkers in sodium hydroxide (NaOH) - induced Crohn's colitis in Wistar rats.
Canadian journal of physiology and pharmacology.
2021 Oct; 99(10):989-999. doi:
10.1139/cjpp-2020-0678. [PMID: 33848442] - Karthikeyan Rajamani, Somasundaram S Thirugnanasambandan, Chidambaram Natesan, Sethupathy Subramaniam, Balasubramanian Thangavel, Natarajan Aravindan. Squalene deters drivers of RCC disease progression beyond VHL status.
Cell biology and toxicology.
2021 08; 37(4):611-631. doi:
10.1007/s10565-020-09566-w. [PMID: 33219891] - Ahmed S Abdel-Latif, Sally E Abu-Risha, Samaa M Bakr, Wafaa M El-Kholy, Mamdouh R El-Sawi. Potassium bromate-induced nephrotoxicity and potential curative role of metformin loaded on gold nanoparticles.
Science progress.
2021 Jul; 104(3):368504211033703. doi:
10.1177/00368504211033703. [PMID: 34293965] - Ibrahim M Alhazza, Iftekhar Hassan, Hossam Ebaid, Jameel Al-Tamimi, Saleh H Alwasel. Chemopreventive effect of riboflavin on the potassium bromate-induced renal toxicity in vivo.
Naunyn-Schmiedeberg's archives of pharmacology.
2020 12; 393(12):2355-2364. doi:
10.1007/s00210-020-01938-7. [PMID: 32666286] - Gökçe Öztürk, Kültiğin Çavuşoğlu, Emine Yalçın. Dose-response analysis of potassium bromate-induced toxicity in Allium cepa L. meristematic cells.
Environmental science and pollution research international.
2020 Dec; 27(34):43312-43321. doi:
10.1007/s11356-020-10294-1. [PMID: 32737776] - Hikmet Memmedov, Latife Merve Oktay, Burak Durmaz, Nur Selvi Günel, Hatice Kalkan Yı Ldırım, Eser Yıldırım Sözmen. Propolis prevents inhibition of apoptosis by potassium bromate in CCD 841 human colon cell.
Cell biochemistry and function.
2020 Jun; 38(4):510-519. doi:
10.1002/cbf.3475. [PMID: 31990996] - Venu Shanmugavel, Kotturu Komala Santhi, Anjali H Kurup, Sureshkumar Kalakandan, Arunkumar Anandharaj, Ashish Rawson. Potassium bromate: Effects on bread components, health, environment and method of analysis: A review.
Food chemistry.
2020 May; 311(?):125964. doi:
10.1016/j.foodchem.2019.125964. [PMID: 31865111] - Iftekhar Hassan, Hossam Ebaid, Ibrahim M Alhazza, Jameel Al-Tamimi. The Alleviative Effect of Vitamin B2 on Potassium Bromate-Induced Hepatotoxicity in Male Rats.
BioMed research international.
2020; 2020(?):8274261. doi:
10.1155/2020/8274261. [PMID: 32802879] - Ahmed A Allam, Sarah I Othman, Ayman M Mahmoud. Deleterious effects of perinatal exposure to potassium bromate on the development of offspring of Swiss mice.
Toxicology and industrial health.
2019 Jan; 35(1):63-78. doi:
10.1177/0748233718814971. [PMID: 30803421] - P O Awoniran, D O Adeyemi. Ethanol extract of Curcuma longa rhizome mitigates potassium bromate-induced liver changes in the Wistar rat: Histological, histochemical and immunohistochemical assessments.
Morphologie : bulletin de l'Association des anatomistes.
2018 Dec; 102(339):276-288. doi:
10.1016/j.morpho.2018.07.004. [PMID: 30195667] - Alice Limonciel, Gamze Ates, Giada Carta, Anja Wilmes, Manfred Watzele, Peter J Shepard, Harper C VanSteenhouse, Bruce Seligmann, Joanne M Yeakley, Bob van de Water, Mathieu Vinken, Paul Jennings. Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq.
Archives of toxicology.
2018 08; 92(8):2517-2531. doi:
10.1007/s00204-018-2256-2. [PMID: 30008028] - Hajer Ben Saad, Dorra Driss, Imen Jaballi, Hanen Ghozzi, Ons Boudawara, Michael Droguet, Christian Magné, Monsef Nasri, Khaled Mounir Zeghal, Ahmed Hakim, Ibtissem Ben Amara. Potassium Bromate-induced Changes in the Adult Mouse Cerebellum Are Ameliorated by Vanillin.
Biomedical and environmental sciences : BES.
2018 Feb; 31(2):115-125. doi:
10.3967/bes2018.014. [PMID: 29606190] - Rahmat Ali Khan. Effect of Launaea procumbens on thyroid glands lipid peroxidation and hormonal dysfunction: a randomized control trial.
Lipids in health and disease.
2017 Sep; 16(1):168. doi:
10.1186/s12944-017-0557-8. [PMID: 28893262] - J Li, M Shi, B Ma, Y Zheng, R Niu, K Li. Protective effects of fraction 4a of polysaccharides isolated from Lycium barbarum against KBrO3-induced renal damage in rats.
Food & function.
2017 Jul; 8(7):2566-2572. doi:
10.1039/c6fo01818a. [PMID: 28671197] - Hajer Ben Saad, Nadia Kharrat, Dorra Driss, Manel Gargouri, Rim Marrakchi, Kamel Jammoussi, Christian Magné, Tahia Boudawara, Samia Ellouz Chaabouni, Khaled Mounir Zeghal, Ahmed Hakim, Ibtissem Ben Amara. Effects of vanillin on potassium bromate-induced neurotoxicity in adult mice: impact on behavior, oxidative stress, genes expression, inflammation and fatty acid composition.
Archives of physiology and biochemistry.
2017 Jul; 123(3):165-174. doi:
10.1080/13813455.2017.1283527. [PMID: 28276710] - Hajer Ben Saad, Manel Gargouri, Fatma Kallel, Rim Chaabene, Tahia Boudawara, Kamel Jamoussi, Christian Magné, Khaled Mounir Zeghal, Ahmed Hakim, Ibtissem Ben Amara. Flavonoid compounds from the red marine alga Alsidium corallinum protect against potassium bromate-induced nephrotoxicity in adult mice.
Environmental toxicology.
2017 May; 32(5):1475-1486. doi:
10.1002/tox.22368. [PMID: 27658546] - Hiroshi Matsumoto, Fumiyo Saito, Masahiro Takeyoshi. Investigation of the early-response genes in chemical-induced renal carcinogenicity for the prediction of chemical carcinogenicity in rats.
The Journal of toxicological sciences.
2017; 42(2):175-181. doi:
10.2131/jts.42.175. [PMID: 28321044] - Hajer Ben Saad, Dorra Driss, Ibtissem Ben Amara, Ons Boudawara, Tahia Boudawara, Samia Ellouz Chaabouni, Khaled Mounir Zeghal, Ahmed Hakim. Altered hepatic mRNA expression of immune response-associated DNA damage in mice liver induced by potassium bromate: Protective role of vanillin.
Environmental toxicology.
2016 Dec; 31(12):1796-1807. doi:
10.1002/tox.22181. [PMID: 26296324] - Naglaa A Bayomy, Gehan M Soliman, Eman Z Abdelaziz. Effect of Potassium Bromate on the Liver of Adult Male Albino Rat and A Possible Protective Role of Vitamin C: Histological, Immunohistochemical, and Biochemical Study.
Anatomical record (Hoboken, N.J. : 2007).
2016 09; 299(9):1256-69. doi:
10.1002/ar.23386. [PMID: 27373450] - Hajer Ben Saad, Dorra Driss, Samia Ellouz Chaabouni, Tahia Boudawara, Khaled Mounir Zeghal, Ahmed Hakim, Ibtissem Ben Amara. Vanillin mitigates potassium bromate-induced molecular, biochemical and histopathological changes in the kidney of adult mice.
Chemico-biological interactions.
2016 May; 252(?):102-13. doi:
10.1016/j.cbi.2016.04.015. [PMID: 27074584] - Mir Kaisar Ahmad, Riaz Mahmood. Protective effect of taurine against potassium bromate-induced hemoglobin oxidation, oxidative stress, and impairment of antioxidant defense system in blood.
Environmental toxicology.
2016 Mar; 31(3):304-13. doi:
10.1002/tox.22045. [PMID: 25213677] - Hajer Ben Saad, Nadia Kharrat, Najeh Krayem, Ons Boudawara, Tahia Boudawara, Najiba Zeghal, Ibtissem Ben Amara. Biological properties of Alsidium corallinum and its potential protective effects against damage caused by potassium bromate in the mouse liver.
Environmental science and pollution research international.
2016 Feb; 23(4):3809-23. doi:
10.1007/s11356-015-5620-2. [PMID: 26498820] - Daisuke Matsuda, Takuya Matsumoto, Kenichi Honma, Ayae Ikawa-Yoshida, Mitsuho Onimaru, Tadashi Furuyama, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Yoshihiko Maehara. BUBR1 Insufficiency in Mice Increases their Sensitivity to Oxidative Stress.
In vivo (Athens, Greece).
2016 11-; 30(6):769-776. doi:
10.21873/invivo.10993. [PMID: 27815460] - H Ben Saad, I Ben Amara, N Krayem, T Boudawara, C Kallel, K M Zeghal, A Hakim. Ameliorative effects of vanillin on potassium bromate induces bone and blood disorders in vivo.
Cellular and molecular biology (Noisy-le-Grand, France).
2015 Nov; 61(7):12-22. doi:
. [PMID: 26567599] - Muhammad Tauseef Sultan, Masood Sadiq Butt, Roselina Karim, Waqas Ahmed, Ubedullah Kaka, Shakeel Ahmad, Saikat Dewanjee, Hawa Z E Jaafar, M Zia-Ul-Haq. Nigella sativa fixed and essential oil modulates glutathione redox enzymes in potassium bromate induced oxidative stress.
BMC complementary and alternative medicine.
2015 Sep; 15(?):330. doi:
10.1186/s12906-015-0853-7. [PMID: 26385559] - Mille Løhr, Annie Jensen, Louise Eriksen, Morten Grønbæk, Steffen Loft, Peter Møller. Association between age and repair of oxidatively damaged DNA in human peripheral blood mononuclear cells.
Mutagenesis.
2015 Sep; 30(5):695-700. doi:
10.1093/mutage/gev031. [PMID: 25925070] - Emiko Okada, Yohei Fujiishi, Kazunori Narumi, Shoichi Kado, Yumi Wako, Kazufumi Kawasako, Kimiyuki Kaneko, Wakako Ohyama. Evaluation of repeated dose micronucleus assays of the liver and gastrointestinal tract using potassium bromate: a report of the collaborative study by CSGMT/JEMS.MMS.
Mutation research. Genetic toxicology and environmental mutagenesis.
2015 Mar; 780-781(?):94-9. doi:
10.1016/j.mrgentox.2014.03.002. [PMID: 24637080] - N E Scholpa, X Zhang, R T Kolli, B S Cummings. Epigenetic changes in p21 expression in renal cells after exposure to bromate.
Toxicological sciences : an official journal of the Society of Toxicology.
2014 Oct; 141(2):432-40. doi:
10.1093/toxsci/kfu138. [PMID: 25015661] - Katrina M Waters, Brian S Cummings, Harish Shankaran, Natalie E Scholpa, Thomas J Weber. ERK oscillation-dependent gene expression patterns and deregulation by stress response.
Chemical research in toxicology.
2014 Sep; 27(9):1496-503. doi:
10.1021/tx500085u. [PMID: 25068892] - Abdulmajeed A Al-Hoqbani, E S Abdel-Halim, Salem S Al-Deyab. Extraction of palm tree cellulose and its functionalization via graft copolymerization.
International journal of biological macromolecules.
2014 Sep; 70(?):275-83. doi:
10.1016/j.ijbiomac.2014.07.009. [PMID: 25020080] - Hajer Ben Saad, Imen Nasri, Awatef Elwej, Najeh Krayem, Raoudha Jarraya, Choumous Kallel, Najiba Zeghal, Ibtissem Ben Amara. A mineral and antioxidant-rich extract from the red marine Algae Alsidium corallinum exhibits cytoprotective effects against potassium bromate-induced erythrocyte oxidative damages in mice.
Biological trace element research.
2014 Jul; 160(1):85-96. doi:
10.1007/s12011-014-0025-5. [PMID: 24913101] - Mir Kaisar Ahmad, Samreen Amani, Riaz Mahmood. Potassium bromate causes cell lysis and induces oxidative stress in human erythrocytes.
Environmental toxicology.
2014 Feb; 29(2):138-45. doi:
10.1002/tox.20780. [PMID: 22012894] - Mir Kaisar Ahmad, Aijaz Ahmed Khan, Riaz Mahmood. Taurine ameliorates potassium bromate-induced kidney damage in rats.
Amino acids.
2013 Nov; 45(5):1109-21. doi:
10.1007/s00726-013-1563-4. [PMID: 23913267] - Darol E Dodd, Debra K Layko, Katherine E Cantwell, Gabrielle A Willson, Russell S Thomas. Subchronic toxicity evaluation of potassium bromate in Fischer 344 rats.
Environmental toxicology and pharmacology.
2013 Nov; 36(3):1227-34. doi:
10.1016/j.etap.2013.10.005. [PMID: 24200600] - Narendrababu Kolisetty, Don A Delker, Srinivasa Muralidhara, Richard J Bull, Joseph A Cotruvo, Jeff W Fisher, Brian S Cummings. Changes in mRNA and protein expression in the renal cortex of male and female F344 rats treated with bromate.
Archives of toxicology.
2013 Nov; 87(11):1911-1925. doi:
10.1007/s00204-013-1052-2. [PMID: 23588252] - Narendrababu Kolisetty, Richard J Bull, Srinivasa Muralidhara, Leah J Costyn, Don A Delker, Zhongxian Guo, Joseph A Cotruvo, Jeffrey W Fisher, Brian S Cummings. Association of brominated proteins and changes in protein expression in the rat kidney with subcarcinogenic to carcinogenic doses of bromate.
Toxicology and applied pharmacology.
2013 Oct; 272(2):391-8. doi:
10.1016/j.taap.2013.06.018. [PMID: 23811332] - Małgorzata Kujawska, Ewa Ignatowicz, Małgorzata Ewertowska, Teresa Adamska, Jarosław Markowski, Jadwiga Jodynis-Liebert. Attenuation of KBrO3-induced renal and hepatic toxicity by cloudy apple juice in rat.
Phytotherapy research : PTR.
2013 Aug; 27(8):1214-9. doi:
10.1002/ptr.4848. [PMID: 23042583] - Rahmat Ali Khan, Muhammad Rashid Khan, Sumaira Sahreen. Protective effects of Sonchus asper (L.) against KBrO₃-induced oxidative stress in rat testis.
Pakistan journal of pharmaceutical sciences.
2013 May; 26(3):567-70. doi:
NULL. [PMID: 23625431] - David A Brott, Patricia Bentley, Murali V P Nadella, Dale Thurman, Jim Fikes, Letitia Cheatham, Frank McGrath, Wenli Luo, Lewis B Kinter. Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent.
Toxicology.
2013 Jan; 303(?):133-8. doi:
10.1016/j.tox.2012.11.003. [PMID: 23159986] - Mir Kaisar Ahmad, Aijaz Ahmed Khan, Riaz Mahmood. Alterations in brush border membrane enzymes, carbohydrate metabolism and oxidative damage to rat intestine by potassium bromate.
Biochimie.
2012 Dec; 94(12):2776-82. doi:
10.1016/j.biochi.2012.09.001. [PMID: 22974983] - Rahmat Ali Khan, Muhammad Rashid Khan, Sumaira Sahreen. Protective effects of Sonchus asper against KBrO3 induced lipid peroxidation in rats.
Lipids in health and disease.
2012 Nov; 11(?):164. doi:
10.1186/1476-511x-11-164. [PMID: 23186106] - Rahmat Ali Khan, Muhamad Rashid Khan, Sumaira Sahreen. Protective effects of rutin against potassium bromate induced nephrotoxicity in rats.
BMC complementary and alternative medicine.
2012 Nov; 12(?):204. doi:
10.1186/1472-6882-12-204. [PMID: 23116356] - Alice Limonciel, Anja Wilmes, Lydia Aschauer, Robert Radford, Katarzyna M Bloch, Tara McMorrow, Walter Pfaller, Joost H van Delft, Craig Slattery, Michael P Ryan, Edward A Lock, Paul Jennings. Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.
Archives of toxicology.
2012 Nov; 86(11):1741-51. doi:
10.1007/s00204-012-0897-0. [PMID: 22760423] - Mir Kaisar Ahmad, Ashreeb Naqshbandi, Mohd Fareed, Riaz Mahmood. Oral administration of a nephrotoxic dose of potassium bromate, a food additive, alters renal redox and metabolic status and inhibits brush border membrane enzymes in rats.
Food chemistry.
2012 Sep; 134(2):980-5. doi:
10.1016/j.foodchem.2012.03.004. [PMID: 23107716] - Mir Kaisar Ahmad, Riaz Mahmood. Oral administration of potassium bromate, a major water disinfection by-product, induces oxidative stress and impairs the antioxidant power of rat blood.
Chemosphere.
2012 May; 87(7):750-6. doi:
10.1016/j.chemosphere.2011.12.073. [PMID: 22277885] - Robert Radford, Craig Slattery, Paul Jennings, Oliver Blacque, Oliver Blaque, Walter Pfaller, Hans Gmuender, Joost Van Delft, Michael P Ryan, Tara McMorrow. Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle.
American journal of physiology. Renal physiology.
2012 Apr; 302(8):F905-16. doi:
10.1152/ajprenal.00427.2011. [PMID: 22262483] - Muhammad Tauseef Sultan, Masood Sadiq Butt, Rabia Shabeer Ahmad, Imran Pasha, Atif Nisar Ahmad, Mir Muhammad Nasir Qayyum. Supplementation of Nigella sativa fixed and essential oil mediates potassium bromate induced oxidative stress and multiple organ toxicity.
Pakistan journal of pharmaceutical sciences.
2012 Jan; 25(1):175-81. doi:
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Analytica chimica acta.
2011 Apr; 690(2):234-9. doi:
10.1016/j.aca.2011.02.030. [PMID: 21435481] - Gordon P McCallum, Michelle Siu, J Nicole Sweeting, Peter G Wells. Methanol exposure does not produce oxidatively damaged DNA in lung, liver or kidney of adult mice, rabbits or primates.
Toxicology and applied pharmacology.
2011 Jan; 250(2):147-53. doi:
10.1016/j.taap.2010.10.004. [PMID: 20950637] - James Keith Ellis, Toby James Athersuch, Rachel Cavill, Robert Radford, Craig Slattery, Paul Jennings, Tara McMorrow, Michael P Ryan, Timothy Mark David Ebbels, Hector Charles Keun. Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.
Molecular bioSystems.
2011 Jan; 7(1):247-57. doi:
10.1039/c0mb00146e. [PMID: 21103459] - Anne Platel, Véronique Gervais, Nicolas Sajot, Fabrice Nesslany, Daniel Marzin, Nancy Claude. Study of gene expression profiles in TK6 human cells exposed to DNA-oxidizing agents.
Mutation research.
2010 Jul; 689(1-2):21-49. doi:
10.1016/j.mrfmmm.2010.04.004. [PMID: 20466008] - Ali Entezam, Adihe Rachel Lokanga, Wei Le, Gloria Hoffman, Karen Usdin. Potassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse model.
Human mutation.
2010 May; 31(5):611-6. doi:
10.1002/humu.21237. [PMID: 20213777] - Xiaoling Zhang, Dilhara De Silva, Bin Sun, Jeffery Fisher, Richard J Bull, Joseph A Cotruvo, Brian S Cummings. Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells.
Toxicology.
2010 Feb; 269(1):13-23. doi:
10.1016/j.tox.2010.01.002. [PMID: 20067818] - Catherine C Priestley, Richard M Green, Michael D Fellows, Ann T Doherty, Nikolas J Hodges, Michael R O'Donovan. Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate.
Toxicology.
2010 Jan; 267(1-3):45-53. doi:
10.1016/j.tox.2009.10.012. [PMID: 19853637] - Magdalena Stasiak, Krzysztof Zasada, Andrzej Lewinski, Małgorzata Karbownik-Lewinska. Melatonin restores the basal level of lipid peroxidation in rat tissues exposed to potassium bromate in vitro.
Neuro endocrinology letters.
2010; 31(3):363-9. doi:
NULL. [PMID: 20588237] - Min Wei, Al-Salmy Hamoud, Takashi Yamaguchi, Anna Kakehashi, Keiichirou Morimura, Kenichiro Doi, Masahiko Kushida, Mitsuaki Kitano, Hideki Wanibuchi, Shoji Fukushima. Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold.
Toxicologic pathology.
2009 Dec; 37(7):983-91. doi:
10.1177/0192623309351720. [PMID: 19833912] - O B Oloyede, T O Sunmonu. Potassium bromate content of selected bread samples in Ilorin, Central Nigeria and its effect on some enzymes of rat liver and kidney.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Aug; 47(8):2067-70. doi:
10.1016/j.fct.2009.05.026. [PMID: 19481132] - Takashi Umemura, Masako Tasaki, Aki Kijima, Toshiya Okamura, Tomoki Inoue, Yuji Ishii, Yuta Suzuki, Norio Masui, Takehiko Nohmi, Akiyoshi Nishikawa. Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate.
Toxicology.
2009 Mar; 257(1-2):46-52. doi:
10.1016/j.tox.2008.12.007. [PMID: 19133310] - Magdalena Stasiak, Andrzej Lewiński, Małgorzata Karbownik-Lewińska. [Relationship between toxic effects of potassium bromate and endocrine glands].
Endokrynologia Polska.
2009 Jan; 60(1):40-50. doi:
". [PMID: 19224504] - Hongmei Yang, Yongsheng Wang, Ying Wang, Junhong Li, Xilin Xiao, Xuan Tan. Study on the interaction among pyronine Y, potassium bromate and naphthols by absorption, three-dimension fluorescence and resonance light scattering spectra and their application.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2008 Dec; 71(4):1290-5. doi:
10.1016/j.saa.2008.03.037. [PMID: 18499514] - Takashi Yamaguchi, Min Wei, Natsuko Hagihara, Masako Omori, Hideki Wanibuchi, Shoji Fukushima. Lack of mutagenic and toxic effects of low dose potassium bromate on kidneys in the Big Blue rat.
Mutation research.
2008 Mar; 652(1):1-11. doi:
10.1016/j.mrgentox.2007.11.004. [PMID: 18243045] - Li Bao, Xin-Sheng Yao, Daniel Tsi, Chin-Chin Yau, Chew-Sern Chia, Hajime Nagai, Hiroshi Kurihara. Protective effects of bilberry (Vaccinium myrtillus L.) extract on KBrO3-induced kidney damage in mice.
Journal of agricultural and food chemistry.
2008 Jan; 56(2):420-5. doi:
10.1021/jf072640s. [PMID: 18092757] - Paweł Jałoszyński, Soichiro Murata, Yasuhiro Shinkai, Satoru Takahashi, Yoshito Kumagai, Susumu Nishimura, Masayuki Yamamoto. Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.
Biochemical and biophysical research communications.
2007 Dec; 364(4):966-71. doi:
10.1016/j.bbrc.2007.10.123. [PMID: 17971305] - Shunji Ueno, Takashige Kashimoto, Nobuyuki Susa, Kensuke Shiho, Takashi Seki, Nobuhiko Ito, Shino Takeda-Homma, Yoshikazu Nishimura, Masayasu Sugiyama. Estimation of hydroxyl radical generation by salicylate hydroxylation method in kidney of mice exposed to ferric nitrilotriacetate and potassium bromate.
Free radical research.
2007 Nov; 41(11):1246-52. doi:
10.1080/10715760701644019. [PMID: 17907000] - Antoine Etou Mongo. Study by scanning electron microscopy of mixture of cereal proteins fractions (maize and wheat) from bread doughs prepared at high temperature in the presence of oxidants.
Pakistan journal of biological sciences : PJBS.
2007 Aug; 10(16):2670-5. doi:
10.3923/pjbs.2007.2670.2675. [PMID: 19070080] - Monica Ropolo, Paolo Degan, Mara Foresta, Mariarosaria D'Errico, Denise Lasigliè, Eugenia Dogliotti, Gianluigi Casartelli, Simonetta Zupo, Alessandro Poggi, Guido Frosina. Complementation of the oxidatively damaged DNA repair defect in Cockayne syndrome A and B cells by Escherichia coli formamidopyrimidine DNA glycosylase.
Free radical biology & medicine.
2007 Jun; 42(12):1807-17. doi:
10.1016/j.freeradbiomed.2007.03.008. [PMID: 17512460] - Angela Mally, Alexander Amberg, Gordon C Hard, Wolfgang Dekant. Are 4-hydroxy-2(E)-nonenal derived mercapturic acids and (1)H NMR metabonomics potential biomarkers of chemically induced oxidative stress in the kidney?.
Toxicology.
2007 Feb; 230(2-3):244-55. doi:
10.1016/j.tox.2006.11.068. [PMID: 17184893] - Małgorzata Karbownik, Magdalena Stasiak, Arkadiusz Zygmunt, Krzysztof Zasada, Andrzej Lewiński. Protective effects of melatonin and indole-3-propionic acid against lipid peroxidation, caused by potassium bromate in the rat kidney.
Cell biochemistry and function.
2006 Nov; 24(6):483-9. doi:
10.1002/cbf.1321. [PMID: 16397908] - Francesca Mattioli, Antonietta Martelli, Marzia Gosmar, Claudia Garbero, Valeria Manfredi, Emanuela Varaldo, Gian Carlo Torre, Giovanni Brambilla. DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid.
Mutation research.
2006 Oct; 609(2):146-53. doi:
10.1016/j.mrgentox.2006.06.028. [PMID: 16942904] - Hiroshi Nishioka, Hajime Fujii, Buxiang Sun, Okezie I Aruoma. Comparative efficacy of oligonol, catechin and (-)-epigallocatechin 3-O-gallate in modulating the potassium bromate-induced renal toxicity in rats.
Toxicology.
2006 Sep; 226(2-3):181-7. doi:
10.1016/j.tox.2006.06.017. [PMID: 16916569] - Takashi Umemura, Keita Kanki, Yuichi Kuroiwa, Yuji Ishii, Keita Okano, Takehiko Nohmi, Akiyoshi Nishikawa, Masao Hirose. In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate.
Cancer science.
2006 Sep; 97(9):829-35. doi:
10.1111/j.1349-7006.2006.00248.x. [PMID: 16805826] - Tsuyoshi Arai, Vincent P Kelly, Osamu Minowa, Tetsuo Noda, Susumu Nishimura. The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA.
Toxicology.
2006 Apr; 221(2-3):179-86. doi:
10.1016/j.tox.2006.01.004. [PMID: 16494984] - Don Delker, Gary Hatch, James Allen, Bobby Crissman, Michael George, David Geter, Steve Kilburn, Tanya Moore, Gail Nelson, Barbara Roop, Ralph Slade, Adam Swank, William Ward, Anthony DeAngelo. Molecular biomarkers of oxidative stress associated with bromate carcinogenicity.
Toxicology.
2006 Apr; 221(2-3):158-65. doi:
10.1016/j.tox.2005.12.011. [PMID: 16442688] - Takashi Umemura, Yuji Kurokawa. Etiology of bromate-induced cancer and possible modes of action-studies in Japan.
Toxicology.
2006 Apr; 221(2-3):154-7. doi:
10.1016/j.tox.2006.01.007. [PMID: 16473452] - Naghma Khan, Sarwat Sultana. Modulatory effect of Ficus racemosa: diminution of potassium bromate-induced renal oxidative injury and cell proliferation response.
Basic & clinical pharmacology & toxicology.
2005 Nov; 97(5):282-8. doi:
10.1111/j.1742-7843.2005.pto_163.x. [PMID: 16236139] - Naghma Khan, Sarwat Sultana. Inhibition of potassium bromate-induced renal oxidative stress and hyperproliferative response by Nymphaea alba in Wistar rats.
Journal of enzyme inhibition and medicinal chemistry.
2005 Jun; 20(3):275-83. doi:
10.1080/14756360400028119. [PMID: 16119199] - Malgorzata Karbownik, Magdalena Stasiak, Krzysztof Zasada, Arkadiusz Zygmunt, Andrzej Lewinski. Comparison of potential protective effects of melatonin, indole-3-propionic acid, and propylthiouracil against lipid peroxidation caused by potassium bromate in the thyroid gland.
Journal of cellular biochemistry.
2005 May; 95(1):131-8. doi:
10.1002/jcb.20404. [PMID: 15723291] - Kevin S McDorman, Brian F Pachkowski, Jun Nakamura, Douglas C Wolf, James A Swenberg. Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products.
Chemico-biological interactions.
2005 Apr; 152(2-3):107-17. doi:
10.1016/j.cbi.2005.02.003. [PMID: 15840384] - Kyong-Son Min, Fumio Morishita, Noriko Tetsuchikawahara, Satomi Onosaka. Induction of hepatic and renal metallothionein synthesis by ferric nitrilotriacetate in mice: the role of MT as an antioxidant.
Toxicology and applied pharmacology.
2005 Apr; 204(1):9-17. doi:
10.1016/j.taap.2004.08.014. [PMID: 15781289] - Liang Ding, Jin-huan Shan, Xiu-mei Wang, Zi-hua Yao, Yu Wang. [Spectrophotometry determination of trace selenium(IV) in Chinese herbal medicine by catalytic kinetics. I. RDB and potassium bromate].
Guang pu xue yu guang pu fen xi = Guang pu.
2004 Nov; 24(11):1419-21. doi:
". [PMID: 15762493] - Naghma Khan, Sarwat Sultana. Abrogation of potassium bromate-induced renal oxidative stress and subsequent cell proliferation response by soy isoflavones in Wistar rats.
Toxicology.
2004 Sep; 201(1-3):173-84. doi:
10.1016/j.tox.2004.04.012. [PMID: 15297031] - Takashi Umemura, Yasuki Kitamura, Keita Kanki, Satoshi Maruyama, Kazushi Okazaki, Takayoshi Imazawa, Tetsuji Nishimura, Ryuichi Hasegawa, Akiyoshi Nishikawa, Masao Hirose. Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate.
Cancer science.
2004 May; 95(5):393-8. doi:
10.1111/j.1349-7006.2004.tb03221.x. [PMID: 15132765] - Naghma Khan, Sonia Sharma, Sarwat Sultana. Attenuation of potassium bromate-induced nephrotoxicity by coumarin (1,2-benzopyrone) in Wistar rats: chemoprevention against free radical-mediated renal oxidative stress and tumor promotion response.
Redox report : communications in free radical research.
2004; 9(1):19-28. doi:
10.1179/135100004225003860. [PMID: 15035824] - Alexander Prange, Barbara Birzele, Johannes Krämer, Hartwig Modrow, Reinhold Chauvistré, Josef Hormes, Peter Köhler. Characterization of sulfur speciation in low molecular weight subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values using x-ray absorption near-edge structure (XANES) spectroscopy.
Journal of agricultural and food chemistry.
2003 Dec; 51(25):7431-8. doi:
10.1021/jf034457e. [PMID: 14640595] - Kevin S McDorman, Michelle J Hooth, Thomas B Starr, Douglas C Wolf. Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products.
Toxicology.
2003 May; 187(1):1-12. doi:
10.1016/s0300-483x(03)00004-0. [PMID: 12679048] - Naghma Khan, Sonia Sharma, Sarwat Sultana. Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress.
Human & experimental toxicology.
2003 Apr; 22(4):193-203. doi:
10.1191/0960327103ht349oa. [PMID: 12755470] - Jinhee Choi, Dae-Yong Kim, Jin-Won Hyun, Sun-Hee Yoon, Eun-Mi Choi, Ki-Baik Hahm, Kwang-Ho Rhee, Myung-Hee Chung. Measurement of oxidative damage at individual gene levels by quantitative PCR using 8-hydroxyguanine glycosylase (OGG1).
Mutation research.
2003 Feb; 523-524(?):225-35. doi:
10.1016/s0027-5107(02)00339-1. [PMID: 12628521] - Yih-Horng Shiao, Sonie I Kamata, Leeanne M Li, Michelle J Hooth, Anthony B DeAngelo, Lucy M Anderson, Douglas C Wolf. Mutations in the VHL gene from potassium bromate-induced rat clear cell renal tumors.
Cancer letters.
2002 Dec; 187(1-2):207-14. doi:
10.1016/s0304-3835(02)00407-x. [PMID: 12359370] - Tsuyoshi Arai, Vincent P Kelly, Osamu Minowa, Tetsuo Noda, Susumu Nishimura. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.
Carcinogenesis.
2002 Dec; 23(12):2005-10. doi:
10.1093/carcin/23.12.2005. [PMID: 12507922] - Satoshi Watanabe, Shin-ichi Togashi, Tetsuya Fukui. Contribution of nitric oxide to potassium bromate-induced elevation of methaemoglobin concentration in mouse blood.
Biological & pharmaceutical bulletin.
2002 Oct; 25(10):1315-9. doi:
10.1248/bpb.25.1315. [PMID: 12392086] - E Olaunde Farombi, Modupe C Alabi, Temitope O Akuru. Kolaviron modulates cellular redox status and impairment of membrane protein activities induced by potassium bromate (KBrO(3)) in rats.
Pharmacological research.
2002 Jan; 45(1):63-8. doi:
10.1006/phrs.2001.0907. [PMID: 11820864] - M Murata, Y Bansho, S Inoue, K Ito, S Ohnishi, K Midorikawa, S Kawanishi. Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.
Chemical research in toxicology.
2001 Jun; 14(6):678-85. doi:
10.1021/tx000209q. [PMID: 11409938] - L M Crosby, K S Hyder, A B DeAngelo, T B Kepler, B Gaskill, G R Benavides, L Yoon, K T Morgan. Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells.
Toxicology and applied pharmacology.
2000 Dec; 169(3):205-21. doi:
10.1006/taap.2000.9049. [PMID: 11133343] - J L Parsons, J K Chipman. The role of glutathione in DNA damage by potassium bromate in vitro.
Mutagenesis.
2000 Jul; 15(4):311-6. doi:
10.1093/mutage/15.4.311. [PMID: 10887209]