Cyanide (BioDeep_00000014358)
Main id: BioDeep_00000230894
PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
[(2R,3S,4R)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][(2R)-1-[3-[(1R,2R,3R,5Z,7S,10Z,12S,13S,15Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-24-id-3-yl]propanoylamino]propan-2-yl]phosphate
化学式: C63H88CoN14O14P (1354.5673717999998)
中文名称: 维生素B12
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3]
InChI: -1
描述信息
B - Blood and blood forming organs > B03 - Antianemic preparations > B03B - Vitamin b12 and folic acid > B03BA - Vitamin b12 (cyanocobalamin and analogues)
D018977 - Micronutrients > D014815 - Vitamins
Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].
Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].
同义名列表
10 个代谢物同义名
[(2R,3S,4R)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl][(2R)-1-[3-[(1R,2R,3R,5Z,7S,10Z,12S,13S,15Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-24-id-3-yl]propanoylamino]propan-2-yl]phosphate; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; Cyanocob(III)alamin; cyanocobalamin; Nascobal Gel; Vitamin�B12; vitamin B12; cobalt(3+); Cyanide; CN-Cbl
数据库引用编号
13 个数据库交叉引用编号
- KEGG: C02823
- KEGGdrug: D00166
- PubChem: 24892734
- PubChem: 16212801
- Metlin: METLIN245
- MeSH: Vitamin B 12
- CAS: 68-19-9
- ChEBI: CHEBI:17439
- PubChem: 5771
- KNApSAcK: C00001534
- NIKKAJI: J203.514F
- medchemexpress: HY-B0315
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-369
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ricco Tindjau, Jian-Yong Chua, Shao-Quan Liu. Co-culturing Propionibacterium freudenreichii and Bifidobacterium animalis subsp. lactis improves short-chain fatty acids and vitamin B12 contents in soy whey.
Food microbiology.
2024 Aug; 121(?):104525. doi:
10.1016/j.fm.2024.104525. [PMID: 38637087] - Yan Liu, Zemin Huang, Hongbin Qiu, Fan Tang, Fengyi Liu, Yiying Zhang, Shanjie Wang. The association between serum methylmalonic acid, cobalamin-related biomarkers, and long-term mortality risk in cancer survivors: a prospective cohort study.
The American journal of clinical nutrition.
2024 May; 119(5):1122-1132. doi:
10.1016/j.ajcnut.2024.02.009. [PMID: 38702109] - Mark Nijland, Solène N Lefebvre, Chancievan Thangaratnarajah, Dirk J Slotboom. Bidirectional ATP-driven transport of cobalamin by the mycobacterial ABC transporter BacA.
Nature communications.
2024 Mar; 15(1):2626. doi:
10.1038/s41467-024-46917-1. [PMID: 38521790] - Lin-Hui Yang, Meng-Zhen Liu, Zi-Lei Chen, Ling-Ling Tong, Dong-Sheng Guo. Lipidomic and transcriptomic analysis of the increase in eicosapentaenoic acid under cobalamin deficiency of Schizochytrium sp.
Biotechnology journal.
2024 Mar; 19(3):e2300612. doi:
10.1002/biot.202300612. [PMID: 38472102] - Yu Zhao, Jian Zhang, Nan Ma, Jinming Kong, Xueji Zhang. Vitamin B12-catalyzed electro-polymerization for ultrasensitive RNA detection.
Bioelectrochemistry (Amsterdam, Netherlands).
2024 Feb; 155(?):108578. doi:
10.1016/j.bioelechem.2023.108578. [PMID: 37742523] - Andrew P Sayer, Marcel Llavero-Pasquina, Katrin Geisler, Andre Holzer, Freddy Bunbury, Gonzalo I Mendoza-Ochoa, Andrew D Lawrence, Martin J Warren, Payam Mehrshahi, Alison G Smith. Conserved cobalamin acquisition protein 1 is essential for vitamin B12 uptake in both Chlamydomonas and Phaeodactylum.
Plant physiology.
2024 Jan; 194(2):698-714. doi:
10.1093/plphys/kiad564. [PMID: 37864825] - Rolland Mutumba, Hannah Pesu, Joseph Mbabazi, Eva Greibe, Ebba Nexo, Mette F Olsen, André Briend, Christian Mølgaard, Kim F Michaelsen, Christian Ritz, Suzanne Filteau, Ezekiel Mupere, Henrik Friis, Benedikte Grenov. Effect of lipid-based nutrient supplements on micronutrient status and hemoglobin among children with stunting: secondary analysis of a randomized, controlled trial in Uganda.
The American journal of clinical nutrition.
2024 Jan; ?(?):. doi:
10.1016/j.ajcnut.2024.01.018. [PMID: 38278366] - Bo Song, Jing Lu, Yanmei Hou, Tong Wu, Xiumei Tao, Dasong Liu, Yancong Wang, Joe M Regenstein, Xiaoming Liu, Peng Zhou. Proteomic Comparisons of Caprine Milk Whole Cream Buttermilk Whey and Cheese Whey Cream Buttermilk.
Journal of agricultural and food chemistry.
2024 Jan; 72(1):933-945. doi:
10.1021/acs.jafc.3c07405. [PMID: 38153029] - Chutikun Kanjanaruch, Kerri A Bochantin, Bethania J Dávila Ruiz, Jessica Syring, Yssi Entzie, Layla King, Pawel P Borowicz, Matthew S Crouse, Joel S Caton, Carl R Dahlen, Alison K Ward, Lawrence P Reynolds. One-carbon metabolite supplementation to nutrient-restricted beef heifers affects placental vascularity during early pregnancy.
Journal of animal science.
2024 Jan; 102(?):. doi:
10.1093/jas/skae044. [PMID: 38407272] - Meryem Al Fatly, Monique T Mulder, Jeanine Roeters van Lennep, Henk J Blom, Kirsten A C Berk. The effect of diet-induced weight loss on circulating homocysteine levels in people with obesity and type 2 diabetes.
Nutrition journal.
2024 Jan; 23(1):2. doi:
10.1186/s12937-023-00908-y. [PMID: 38167024] - Xiaojuan Luo, Jieying Wang, Zhenhu Lin, Jiwei Zhao, Ke Cao, Jinlin Liu. Megaloblastic anemia and benign proteinuria: Clues to the diagnosis of Imerslund-Gräsbeck syndrome.
Pediatric blood & cancer.
2024 Jan; 71(1):e30731. doi:
10.1002/pbc.30731. [PMID: 37855200] - Joseph Boachie, Victor Zammit, Ponnusamy Saravanan, Antonysunil Adaikalakoteswari. Metformin Inefficiency to Lower Lipids in Vitamin B12 Deficient HepG2 Cells Is Alleviated via Adiponectin-AMPK Axis.
Nutrients.
2023 Dec; 15(24):. doi:
10.3390/nu15245046. [PMID: 38140305] - Ilia A Dereven'kov, Larissa A Maiorova, Oscar I Koifman, Denis S Salnikov. High Reactivity of Supermolecular Nanoentities of a Vitamin B12 Derivative in Langmuir-Schaefer Films Toward Gaseous Toxins.
Langmuir : the ACS journal of surfaces and colloids.
2023 12; 39(48):17240-17250. doi:
10.1021/acs.langmuir.3c02317. [PMID: 38050683] - Inés Domínguez-López, Rosa Casas, Gemma Chiva-Blanch, Miguel Ángel Martínez-González, Montserrat Fitó, Emilio Ros, Rosa M Lamuela-Raventós, Ramon Estruch. Serum vitamin B12 concentration is associated with improved memory in older individuals with higher adherence to the Mediterranean diet.
Clinical nutrition (Edinburgh, Scotland).
2023 12; 42(12):2562-2568. doi:
10.1016/j.clnu.2023.10.025. [PMID: 37948836] - Alessia Aureli, Rosanna Recupero, Michela Mariani, Melania Manco, Francesco Carlomagno, Sarah Bocchini, Mirella Nicodemo, Maria Rosaria Marchili, Stefano Cianfarani, Marco Cappa, Danilo Fintini. Low Levels of Serum Total Vitamin B12 Are Associated with Worse Metabolic Phenotype in a Large Population of Children, Adolescents and Young Adults, from Underweight to Severe Obesity.
International journal of molecular sciences.
2023 Nov; 24(23):. doi:
10.3390/ijms242316588. [PMID: 38068910] - Savitesh Kushwaha, Rachana Srivastava, Sanjay Kumar Bhadada, Nizamuddin Khan, Atreyo Mondal, Poonam Khanna. Interaction between micronutrients and lipid profile in prediabetes and diabetes among school-aged children (5-9 y) in India.
Nutrition (Burbank, Los Angeles County, Calif.).
2023 11; 115(?):112172. doi:
10.1016/j.nut.2023.112172. [PMID: 37611504] - Rebecca R Procknow, Kristopher J Kennedy, Maxwell Kluba, Lesley J Rodriguez, Michiko E Taga. Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches.
mBio.
2023 Oct; 14(5):e0158823. doi:
10.1128/mbio.01588-23. [PMID: 37823641] - Nicola A Gillies, Amber M Milan, David Cameron-Smith, Karen D Mumme, Cathryn A Conlon, Pamela R von Hurst, Crystal F Haskell-Ramsay, Beatrix Jones, Nicole C Roy, Jane Coad, Clare R Wall, Kathryn L Beck. Vitamin B and One-Carbon Metabolite Profiles Show Divergent Associations with Cardiometabolic Risk Markers but not Cognitive Function in Older New Zealand Adults: A Secondary Analysis of the REACH Study.
The Journal of nutrition.
2023 Oct; ?(?):. doi:
10.1016/j.tjnut.2023.10.012. [PMID: 37863266] - Marcelo Gomes Soares, Gabriel Cicalese Bevilaqua, Érika Maria Marcondes Tassi, Vivian Consuelo Reolon Schmidt. Fermented foods and beverages: a potential in situ vitamin B12 biofortification - a literature review.
International journal of food sciences and nutrition.
2023 Sep; 74(6):655-667. doi:
10.1080/09637486.2023.2248422. [PMID: 37612883] - Kinga Ilona Nyulas, Mariana Cornelia Tilinca, Sándor Pál, Erzsébet Májai Fogarasi, Mircea Dumitru Croitoru, Robert Gabriel Tripon, Zoltán Preg, Márta Germán-Salló, Zsuzsánna Simon-Szabó, Enikő Nemes-Nagy. Assessment of vitamin B12 levels and cardiovascular risk factors in metformin- and non-metformin-treated type 2 diabetic patients.
Pakistan journal of pharmaceutical sciences.
2023 Sep; 36(5):1399-1405. doi:
". [PMID: 37869915] - Jennifer K Frediani, Asim A Lal, Esther Kim, Sharon L Leslie, David W Boorman, Vinita Singh. The role of diet and non-pharmacologic supplements in the treatment of chronic neuropathic pain: A systematic review.
Pain practice : the official journal of World Institute of Pain.
2023 Aug; ?(?):. doi:
10.1111/papr.13291. [PMID: 37654090] - Jennifer Scott, Jorge Amich. The role of methionine synthases in fungal metabolism and virulence.
Essays in biochemistry.
2023 Jul; ?(?):. doi:
10.1042/ebc20230007. [PMID: 37449444] - Christopher F Jensen. Vitamin B12 levels in children and adolescents on plant-based diets: a systematic review and meta-analysis.
Nutrition reviews.
2023 07; 81(8):951-966. doi:
10.1093/nutrit/nuac096. [PMID: 36413044] - Tattari Shalini, Raghu Pullakhandam, Santu Ghosh, Bharati Kulkarni, Hemalatha Rajkumar, Harshpal S Sachdev, Anura V Kurpad, Geereddy Bhanuprakash Reddy. Prevalence of Vitamin B12 and Folate Deficiencies in Indian Children and Adolescents.
Nutrients.
2023 Jul; 15(13):. doi:
10.3390/nu15133026. [PMID: 37447351] - Helena Ferreira, Marta Vasconcelos, Ana M Gil, Beatriz Oliveira, Elisete Varandas, Eugénia Vilela, Kimhuong Say, Joana Silveira, Elisabete Pinto. Impact of a daily legume-based meal on dietary and nutritional intake in a group of omnivorous adults.
Nutrition bulletin.
2023 06; 48(2):190-202. doi:
10.1111/nbu.12613. [PMID: 37070278] - Irena Ujianti, Imelda Rosalyn Sianipar, Ani Retno Prijanti, Irsan Hasan, Wawaimuli Arozal, Ahmad Aulia Jusuf, Heri Wibowo, Joedo Prihartono, Patwa Amani, Dewi Irawati Soeria Santoso. Effect of Roselle Flower Extract (Hibiscus sabdariffa Linn.) on Reducing Steatosis and Steatohepatitis in Vitamin B12 Deficiency Rat Model.
Medicina (Kaunas, Lithuania).
2023 May; 59(6):. doi:
10.3390/medicina59061044. [PMID: 37374248] - Aoi Yamamoto, Mahiro Seki, Kyohei Koseki, Yukinori Yabuta, Katsuhiko Shimizu, Jiro Arima, Fumio Watanabe, Tomohiro Bito. Production and characterization of cyanocobalamin-enriched tomato (Solanum lycopersicum) fruits grown using hydroponics.
Journal of the science of food and agriculture.
2023 May; 103(7):3685-3690. doi:
10.1002/jsfa.12297. [PMID: 36321533] - C L Girard, M Duplessis. Review - State of knowledge on the importance of folates and cobalamin for dairy cow metabolism.
Animal : an international journal of animal bioscience.
2023 Apr; ?(?):100834. doi:
10.1016/j.animal.2023.100834. [PMID: 37210233] - Hongbing Sun, Connie M Weaver. Trends in Diet Quality and Increasing Inadequacies of Micronutrients Vitamin C, Vitamin B12, Iron and Potassium in US Type 2 Diabetic Adults.
Nutrients.
2023 Apr; 15(8):. doi:
10.3390/nu15081980. [PMID: 37111200] - Arpita Das, Chyi-Huey Bai, Jung-Su Chang, Ya-Li Huang, Fan-Fen Wang, Yi-Chun Chen, Jane C-J Chao. Associations of Dietary Patterns and Vitamin D Levels with Iron Status in Pregnant Women: A Cross-Sectional Study in Taiwan.
Nutrients.
2023 Apr; 15(8):. doi:
10.3390/nu15081805. [PMID: 37111023] - Ali Niklewicz, A David Smith, Alison Smith, Andre Holzer, Andrew Klein, Andrew McCaddon, Anne M Molloy, Bruce H R Wolffenbuttel, Ebba Nexo, Helene McNulty, Helga Refsum, Jean-Louis Gueant, Marie-Joe Dib, Mary Ward, Michelle Murphy, Ralph Green, Kourosh R Ahmadi, Luciana Hannibal, Martin J Warren, P Julian Owen. The importance of vitamin B12 for individuals choosing plant-based diets.
European journal of nutrition.
2023 Apr; 62(3):1551-1559. doi:
10.1007/s00394-022-03025-4. [PMID: 36469110] - Fengping Sun, Liqin Chao, Junxia Zhang, Xiaoli Pan. Exercise combined with lysine-inositol vitamin B12 promotes height growth in children with idiopathic short stature.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
2023 Apr; 69-70(?):101535. doi:
10.1016/j.ghir.2023.101535. [PMID: 37245296] - Guangqing Liu, Huiying Wang, Baisong Tong, Yali Cui, Sibylle C Vonesch, Huina Dong, Dawei Zhang. An Efficient CRISPR/Cas12e System for Genome Editing in Sinorhizobium meliloti.
ACS synthetic biology.
2023 03; 12(3):898-903. doi:
10.1021/acssynbio.2c00629. [PMID: 36795971] - Seyedeh Fatemeh Hoseinlar, Masoud Nikanfar, Delara Laghousi, Masoud Darabi, Behrouz Shademan, Alireza Nourazarian. Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease.
Clinical laboratory.
2023 Mar; 69(3):. doi:
10.7754/clin.lab.2022.220614. [PMID: 36912305] - Denia Cai Shi, Chunlin Long, Ella Vardeman, Edward J Kennelly, Michael A Lawton, Rong Di. Potential Anti-Alzheimer Properties of Mogrosides in Vitamin B12-Deficient Caenorhabditis elegans.
Molecules (Basel, Switzerland).
2023 Feb; 28(4):. doi:
10.3390/molecules28041826. [PMID: 36838815] - Wen-Long Sun, Sha Hua, Xin-Yu Li, Liang Shen, Hao Wu, Hong-Fang Ji. Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin.
Nature communications.
2023 01; 14(1):477. doi:
10.1038/s41467-023-36079-x. [PMID: 36717576] - Sophie Ketter, Benesh Joseph. Gd3+-Trityl-Nitroxide Triple Labeling and Distance Measurements in the Heterooligomeric Cobalamin Transport Complex in the Native Lipid Bilayers.
Journal of the American Chemical Society.
2023 01; 145(2):960-966. doi:
10.1021/jacs.2c10080. [PMID: 36599418] - Xun Pei, Junjie Yao, Simiao Ran, Haifei Lu, Shuo Yang, Yini Zhang, Miyuan Wang, Heyuan Shi, Aihua Tan. Association of serum water-soluble vitamin exposures with the risk of metabolic syndrome: results from NHANES 2003-2006.
Frontiers in endocrinology.
2023; 14(?):1167317. doi:
10.3389/fendo.2023.1167317. [PMID: 37251666] - Erika Castaño-Moreno, Ana María Ronco, Paola Casanello. Metabolic Interaction Between Folate, Vitamin B12, and Polyunsaturated Fatty Acids in Pregnancy.
Advances in experimental medicine and biology.
2023; 1428(?):83-98. doi:
10.1007/978-3-031-32554-0_4. [PMID: 37466770] - Maximilian Andreas Storz, Alexander Müller, Lisa Niederreiter, Amy M Zimmermann-Klemd, Martin Suarez-Alvarez, Stefanie Kowarschik, Monique Strittmatter, Evelyn Schlachter, Cristian Pasluosta, Roman Huber, Luciana Hannibal. A cross-sectional study of nutritional status in healthy, young, physically-active German omnivores, vegetarians and vegans reveals adequate vitamin B12 status in supplemented vegans.
Annals of medicine.
2023; 55(2):2269969. doi:
10.1080/07853890.2023.2269969. [PMID: 37851870] - Beatriz Marques de Brito, Vinícius de Menezes Campos, Félix Jesus Neves, Luiz Roberto Ramos, Luciana Yuki Tomita. Vitamin B12 sources in non-animal foods: a systematic review.
Critical reviews in food science and nutrition.
2023; 63(26):7853-7867. doi:
10.1080/10408398.2022.2053057. [PMID: 35343314] - Zachary F Hallberg, Erica C Seth, Kersh Thevasundaram, Michiko E Taga. Comparative Analysis of Corrinoid Profiles across Host-Associated and Environmental Samples.
Biochemistry.
2022 12; 61(24):2791-2796. doi:
10.1021/acs.biochem.2c00367. [PMID: 36037062] - Farnaz Pouriayevali, Marziyeh Tavalaee, Taghi Taktaz-Hafshejani, Maurizio Dattilio, Mohammad H Nasr-Esfahani. Overlapping sperm damages from vitamin B or D deficiency in mice: Insights into the role of clinical supplementations.
Andrologia.
2022 Dec; 54(11):e14592. doi:
10.1111/and.14592. [PMID: 36123798] - Larissa Balabanova, Iuliia Pentekhina, Olga Nedashkovskaya, Anton Degtyarenko, Valeria Grigorchuk, Yulia Yugay, Elena Vasyutkina, Olesya Kudinova, Aleksandra Seitkalieva, Lubov Slepchenko, Oksana Son, Liudmila Tekutyeva, Yury Shkryl. Shift of Choline/Betaine Pathway in Recombinant Pseudomonas for Cobalamin Biosynthesis and Abiotic Stress Protection.
International journal of molecular sciences.
2022 Nov; 23(22):. doi:
10.3390/ijms232213934. [PMID: 36430408] - Sotirios Vasileiadis, Chiara Perruchon, Benjamin Scheer, Lorenz Adrian, Nicole Steinbach, Marco Trevisan, Patricia Plaza-Bolaños, Ana Agüera, Antonis Chatzinotas, Dimitrios G Karpouzas. Nutritional inter-dependencies and a carbazole-dioxygenase are key elements of a bacterial consortium relying on a Sphingomonas for the degradation of the fungicide thiabendazole.
Environmental microbiology.
2022 11; 24(11):5105-5122. doi:
10.1111/1462-2920.16116. [PMID: 35799498] - Chang-Woo Lee, Joon-Soo Jin, Seungwon Kwon, Chul Jin, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho. Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis.
Complementary therapies in clinical practice.
2022 Nov; 49(?):101657. doi:
10.1016/j.ctcp.2022.101657. [PMID: 36007447] - Kristopher J Kennedy, Florian J Widner, Olga M Sokolovskaya, Lina V Innocent, Rebecca R Procknow, Kenny C Mok, Michiko E Taga. Cobalamin Riboswitches Are Broadly Sensitive to Corrinoid Cofactors to Enable an Efficient Gene Regulatory Strategy.
mBio.
2022 10; 13(5):e0112122. doi:
10.1128/mbio.01121-22. [PMID: 35993747] - Huynh Thi Ngoc Mi, Santipap Chaiyasarn, Bekir Engin Eser, Steven R Susanto Tan, Supawadee Burapan, Jaehong Han. Allyl Aryl Ether Cleavage by Blautia sp. MRG-PMF1 Cocorrinoid O-Demethylase.
Microbiology spectrum.
2022 10; 10(5):e0330522. doi:
10.1128/spectrum.03305-22. [PMID: 36197289] - Adarsha Gupta, Max J H Worthington, Justin M Chalker, Munish Puri. Integration of the Exogenous Tuning of Thraustochytrid Fermentation and Sulfur Polymerization of Single-Cell Oil for Developing Plant-like Oils.
Marine drugs.
2022 Oct; 20(10):. doi:
10.3390/md20100655. [PMID: 36286478] - Chun Gan, Xindi Zhou, Dan Chen, Huan Chi, Jiawen Qiu, Hui You, Yaxi Chen, Mo Wang, Haiping Yang, Wei Jiang, Qiu Li. Novel pathogenic variants in CUBN uncouple proteinuria from renal function.
Journal of translational medicine.
2022 10; 20(1):480. doi:
10.1186/s12967-022-03706-y. [PMID: 36266725] - B William Ogunkolade, Antonysunil Adaikalakoteswari, Shirleny Romualdo Cardoso, Rob Lowe, Nisha Patel, Vardhman Rakyan, Sarah Finer, Martin Wabitsch, Ponnusamy Saravanan, Gyanendra Tripathi, Elena Bochukova, Graham A Hitman. An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes.
Epigenetics.
2022 10; 17(10):1219-1233. doi:
10.1080/15592294.2021.2003043. [PMID: 34818986] - Michelle Cora. Black Cohosh Herbal Extract and Hematologic Alterations in B6C3F1/N Mice.
Toxicologic pathology.
2022 10; 50(7):886-889. doi:
10.1177/01926233221133549. [PMID: 36373576] - Rui Wang, Yan Bai, Yu Yang. Effects of dietary supplementation of different levels of vitamin B12 on the liver metabolism of laying hens.
Journal of the science of food and agriculture.
2022 Oct; 102(13):5787-5794. doi:
10.1002/jsfa.11928. [PMID: 35411555] - Aakriti Singh, Ganesh Yadagiri, Aaqib Javaid, Krishna Kumar Sharma, Anurag Verma, Om Prakash Singh, Shyam Sundar, Shyam Lal Mudavath. Hijacking the intrinsic vitamin B12 pathway for the oral delivery of nanoparticles, resulting in enhanced in vivo anti-leishmanial activity.
Biomaterials science.
2022 Sep; 10(19):5669-5688. doi:
10.1039/d2bm00979j. [PMID: 36017751] - Shenlu Qin, Yihan Wang, Lili Li, Junli Liu, Congmei Xiao, Duo Duan, Wanyu Hao, Chunxia Qin, Jie Chen, Luxia Yao, Runshuai Zhang, Jia You, Ju-Sheng Zheng, Enzhi Shen, Lianfeng Wu. Early-life vitamin B12 orchestrates lipid peroxidation to ensure reproductive success via SBP-1/SREBP1 in Caenorhabditis elegans.
Cell reports.
2022 09; 40(12):111381. doi:
10.1016/j.celrep.2022.111381. [PMID: 36130518] - Justyna Godos, Francesca Giampieri, Wahidah H Al-Qahtani, Francesca Scazzina, Marialaura Bonaccio, Giuseppe Grosso. Ultra-Processed Food Consumption and Relation with Diet Quality and Mediterranean Diet in Southern Italy.
International journal of environmental research and public health.
2022 09; 19(18):. doi:
10.3390/ijerph191811360. [PMID: 36141629] - Wei Chen, Zhihua Si, Yanping Bi, Bing Yang. An unusual case of subacute combined degeneration due to nitrous oxide abuse, which relapsed after bariatric surgery: A case report.
Medicine.
2022 Sep; 101(35):e30442. doi:
10.1097/md.0000000000030442. [PMID: 36107547] - Zhehui Chen, Hui Dong, Yupeng Liu, Ruxuan He, Jinqing Song, Ying Jin, Mengqiu Li, Yi Liu, Xueqin Liu, Hui Yan, Jianguang Qi, Fang Wang, Huijie Xiao, Hong Zheng, Lulu Kang, Dongxiao Li, Yao Zhang, Yanling Yang. Late-onset cblC deficiency around puberty: a retrospective study of the clinical characteristics, diagnosis, and treatment.
Orphanet journal of rare diseases.
2022 09; 17(1):330. doi:
10.1186/s13023-022-02471-x. [PMID: 36056359] - Eva Kiessling, Florian Peters, Lynn J A Ebner, Luca Merolla, Marijana Samardzija, Matthias R Baumgartner, Christian Grimm, D Sean Froese. HIF1 and DROSHA are involved in MMACHC repression in hypoxia.
Biochimica et biophysica acta. General subjects.
2022 09; 1866(9):130175. doi:
10.1016/j.bbagen.2022.130175. [PMID: 35636712] - Sebastian Gude, Gordon J Pherribo, Michiko E Taga. A Salvaging Strategy Enables Stable Metabolite Provisioning among Free-Living Bacteria.
mSystems.
2022 08; 7(4):e0028822. doi:
10.1128/msystems.00288-22. [PMID: 35924847] - Portia Keabetswe Lekhanya, Kabelo Mokgalaboni. Exploring the effectiveness of vitamin B12 complex and alpha-lipoic acid as a treatment for diabetes mellitus/neuropathy: a protocol for systematic review and meta-analysis of randomised controlled trials.
BMJ open.
2022 08; 12(8):e065630. doi:
10.1136/bmjopen-2022-065630. [PMID: 36008079] - Elena Leoni Theiss, Lea Victoria Griebsch, Anna Andrea Lauer, Daniel Janitschke, Vincent Konrad Johannes Erhardt, Elodie Christiane Haas, Konstantin Nicolas Kuppler, Juliane Radermacher, Oliver Walzer, Dorothea Portius, Heike Sabine Grimm, Tobias Hartmann, Marcus Otto Walter Grimm. Vitamin B12 Attenuates Changes in Phospholipid Levels Related to Oxidative Stress in SH-SY5Y Cells.
Cells.
2022 08; 11(16):. doi:
10.3390/cells11162574. [PMID: 36010649] - Mehmet A Dundar, Yasemin A Torun, Feyza Cetin, Hatice T Oz. Endothelium-derived Microparticles Are Increased in Teenagers With Cobalamin Deficiency.
Journal of pediatric hematology/oncology.
2022 08; 44(6):e918-e922. doi:
10.1097/mph.0000000000002286. [PMID: 34387625] - Antonio José Guillot, Pablo Merino-Gutiérrez, Andrea Bocchino, Conor O'Mahony, Rosa Maria Giner, Maria Carmen Recio, Teresa Maria Garrigues, Ana Melero. Exploration of Microneedle-assisted skin delivery of cyanocobalamin formulated in ultraflexible lipid vesicles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2022 Aug; 177(?):184-198. doi:
10.1016/j.ejpb.2022.06.015. [PMID: 35787430] - Xiao Chen, Jiaxi Yang, Hui Zhang, Yuhui Huang, Yaying Cao, Shiyu Yan, Geng Zong, Yan Zheng, Xiaofeng Wang, Changzheng Yuan. Plasma folate levels in relation to cognitive impairment: a community-based cohort of older adults in China.
European journal of nutrition.
2022 Aug; 61(5):2837-2845. doi:
10.1007/s00394-022-02825-y. [PMID: 35303753] - David S H Bell. Metformin-induced vitamin B12 deficiency can cause or worsen distal symmetrical, autonomic and cardiac neuropathy in the patient with diabetes.
Diabetes, obesity & metabolism.
2022 08; 24(8):1423-1428. doi:
10.1111/dom.14734. [PMID: 35491956] - Fang Liu, Yuanyuan Wu, Zhi Li, Ruihua Wan. Identification of MMACHC and ZEB2 mutations causing coexistent cobalamin C disease and Mowat-Wilson syndrome in a 2-year-old girl.
Clinica chimica acta; international journal of clinical chemistry.
2022 Aug; 533(?):31-39. doi:
10.1016/j.cca.2022.06.004. [PMID: 35709987] - Pierce Marsden, Aakriti A Sharma, Joe-Anthony Rotella. Review article: Clinical manifestations and outcomes of chronic nitrous oxide misuse: A systematic review.
Emergency medicine Australasia : EMA.
2022 08; 34(4):492-503. doi:
10.1111/1742-6723.13997. [PMID: 35695047] - Friederike I Tam, Ilektra Chocholi, Inger Hellerhoff, Malina Kloepfer, Kerstin Weidner, Veit Roessner, Peter Mirtschink, David M Poitz, Stefan Ehrlich. Liver and vitamin B12 parameters in patients with anorexia nervosa before and after short-term weight restoration.
Psychiatry research.
2022 08; 314(?):114673. doi:
10.1016/j.psychres.2022.114673. [PMID: 35751997] - Jeliyah Clark, Paige Bommarito, Miroslav Stýblo, Marisela Rubio-Andrade, Gonzalo G García-Vargas, Mary V Gamble, Rebecca C Fry. Maternal serum concentrations of one-carbon metabolism factors modify the association between biomarkers of arsenic methylation efficiency and birth weight.
Environmental health : a global access science source.
2022 Jul; 21(1):68. doi:
10.1186/s12940-022-00875-7. [PMID: 35836250] - Marsha E Samson, Lorraine F Yeung, Charles E Rose, Yan Ping Qi, Christopher A Taylor, Krista S Crider. Vitamin B-12 malabsorption and renal function are critical considerations in studies of folate and vitamin B-12 interactions in cognitive performance: NHANES 2011-2014.
The American journal of clinical nutrition.
2022 07; 116(1):74-85. doi:
10.1093/ajcn/nqac065. [PMID: 35584808] - Freddy Bunbury, Evelyne Deery, Andrew P Sayer, Vaibhav Bhardwaj, Ellen L Harrison, Martin J Warren, Alison G Smith. Exploring the onset of B12 -based mutualisms using a recently evolved Chlamydomonas auxotroph and B12 -producing bacteria.
Environmental microbiology.
2022 07; 24(7):3134-3147. doi:
10.1111/1462-2920.16035. [PMID: 35593514] - A Boussetta, M Jellouli, R Maamouri, A Talbi, H Skhiri, T Gargah. Acute renal failure in a 7-year-old boy: do not miss rare and treatable cause.
Journal of nephrology.
2022 Jul; 35(6):1731-1735. doi:
10.1007/s40620-021-01190-z. [PMID: 34773602] - Sunmin Park, Sunna Kang, Da Sol Kim. Folate and vitamin B-12 deficiencies additively impaire memory function and disturb the gut microbiota in amyloid-β infused rats.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2022 Jul; 92(3-4):169-181. doi:
10.1024/0300-9831/a000624. [PMID: 31841076] - Özen Taş, Tugba Kontbay, Ozlem Dogan, Engin Kose, Merih Berberoglu, Zeynep Siklar, Leyla Tumer, Fatma Tuba Eminoglu. Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?.
Klinische Padiatrie.
2022 Jul; 234(4):221-227. doi:
10.1055/a-1702-2614. [PMID: 35114702] - Merve Çebi, Barış Metin, Nevzat Tarhan. The association between vitamin B12 and plasma homocysteine levels with episodic memory and the volume of memory related brain structures in middle-aged individuals: a retrospective correlational study.
Brain structure & function.
2022 Jul; 227(6):2103-2109. doi:
10.1007/s00429-022-02499-6. [PMID: 35499579] - Sjoerd N Duim, L Tom Vlasveld, Stephanie T P Mezger, Alma M A Mingels, Christian R B Ramakers, Douwe de Boer, Sandra G Heil, Ebba Nexo, André P van Rossum. "Macro transcobalamin causing raised vitamin B12: Case-based laboratory investigation".
Annals of clinical biochemistry.
2022 07; 59(4):302-307. doi:
10.1177/00045632221087132. [PMID: 35352974] - Jing Luan, Hui Zou, Yazhou Cui, Jing Wang, Zhenzhong Han, Genglin Zhang, Jinxiang Han. Generation of induced pluripotent stem cells named SMBCi019-A from a methylmalonic acidemia patient carrying the MMACHC mutations.
Stem cell research.
2022 07; 62(?):102821. doi:
10.1016/j.scr.2022.102821. [PMID: 35660814] - Hanie Matin, Farzaneh Taghian, Ahmad Chitsaz. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2022 Jul; 43(7):4413-4424. doi:
10.1007/s10072-021-05843-6. [PMID: 35112219] - Mohammad Sadegh Hesamian, Vahid Shaygannejad, Marjan Golabi, Omid Mirmosayyeb, Alireza Andalib, Nahid Eskandari. The Role of Cobalamin on Interleukin 10, Osteopontin, and Related MicroRNAs in Multiple Sclerosis.
Iranian journal of allergy, asthma, and immunology.
2022 Jun; 21(3):332-343. doi:
10.18502/ijaai.v21i3.9806. [PMID: 35822683] - Scott Ailliet, Rik Vandenberghe, Toon Schiemsky, Lode Van Overbeke, Philippe Demaerel, Wouter Meersseman, David Cassiman, Pieter Vermeersch. A case of vitamin B12 deficiency neurological syndrome in a young adult due to late-onset cobalamin C (CblC) deficiency: a diagnostic challenge.
Biochemia medica.
2022 Jun; 32(2):020802. doi:
10.11613/bm.2022.020802. [PMID: 35464742] - Christopher J Cifelli, Sanjiv Agarwal, Victor L Fulgoni Iii. Association between Intake of Total Dairy and Individual Dairy Foods and Markers of Folate, Vitamin B6 and Vitamin B12 Status in the U.S. Population.
Nutrients.
2022 Jun; 14(12):. doi:
10.3390/nu14122441. [PMID: 35745171] - Zhe Ding, Lihui Luo, Shaohui Guo, Qing Shen, Yueying Zheng, Shengmei Zhu. Non-Linear Association between Folate/Vitamin B12 Status and Cognitive Function in Older Adults.
Nutrients.
2022 Jun; 14(12):. doi:
10.3390/nu14122443. [PMID: 35745173] - Mengru Li, Xiaotian Chen, Yi Zhang, Hongyan Chen, Dingmei Wang, Chao Cao, Yuan Jiang, Xiangyuan Huang, Yalan Dou, Yin Wang, Xiaojing Ma, Wei Sheng, Weili Yan, Guoying Huang. RBC Folate and Serum Folate, Vitamin B-12, and Homocysteine in Chinese Couples Prepregnancy in the Shanghai Preconception Cohort.
The Journal of nutrition.
2022 06; 152(6):1496-1506. doi:
10.1093/jn/nxac050. [PMID: 35259272] - Hussam Ibrahim, Shihao Yin, Satyanarayana Moru, Yunjiao Zhu, Michael J Castellano, Liang Dong. In Planta Nitrate Sensor Using a Photosensitive Epoxy Bioresin.
ACS applied materials & interfaces.
2022 Jun; 14(22):25949-25961. doi:
10.1021/acsami.2c01988. [PMID: 35638646] - Andreas S Papazoglou, Dimitrios V Moysidis, Christos Tsagkaris, Ioannis Vouloagkas, Efstratios Karagiannidis, Anastasios Kartas, Nikolaos Vlachopoulos, Georgios Konstantinou, Georgios Sofidis, Nikolaos Stalikas, Eleftherios Panteris, Olga Deda, Nikolaos Otountzidis, Haralambos Karvounis, Helen Gika, Georgios Theodoridis, Georgios Sianos. Impact of religious fasting on metabolic and hematological profile in both dyslipidemic and non-dyslipidemic fasters.
European journal of clinical nutrition.
2022 Jun; 76(6):891-898. doi:
10.1038/s41430-021-01053-7. [PMID: 34853413] - Ulf Wike Ljungblad, Henriette Astrup, Lars Mørkrid, Helle Borgstrøm Hager, Morten Lindberg, Erik A Eklund, Anne-Lise Bjørke-Monsen, Terje Rootwelt, Trine Tangeraas. Breastfed Infants With Spells, Tremor, or Irritability: Rule Out Vitamin B12 Deficiency.
Pediatric neurology.
2022 06; 131(?):4-12. doi:
10.1016/j.pediatrneurol.2022.03.003. [PMID: 35439713] - William D Wood, Ayah Elmaghrabi, Garrett Gotway, Matthias T F Wolf. The roles of homocysteinemia and methylmalonic acidemia in kidney injury in atypical hemolytic uremic syndrome caused by cobalamin C deficiency.
Pediatric nephrology (Berlin, Germany).
2022 06; 37(6):1415-1418. doi:
10.1007/s00467-021-05372-6. [PMID: 34854955] - Melda Kangalgil, Ayhan Şahinler, Ayşe Özfer Özçelik. Maternal micronutrient status and its association with sociodemographic, maternal, and dietary factors in a cross-sectional study.
The journal of obstetrics and gynaecology research.
2022 Jun; 48(6):1328-1336. doi:
10.1111/jog.15237. [PMID: 35332609] - Ahu Yorulmaz, Yildiz Hayran, Ahmet Kagan Ozdemir, Orhan Sen, Ilgaz Genc, Gunes Gur Aksoy, Basak Yalcin. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium.
Journal of cosmetic dermatology.
2022 Jun; 21(6):2610-2617. doi:
10.1111/jocd.14413. [PMID: 34449961] - Peng Zou, Xiaoping Zhang, Rui Zhang, Jun-Song Yang, Lei Chu, Xiang-Fu Wang, Jian-Min Wei, Xin Chai, Yuan-Ting Zhao, Bo Liao. The feasibility and safety of cocktail treatment of triple anti-inflammatory agents loaded with gelatin sponge promotes early recovery after posterior percutaneous endoscopic cervical discectomy.
Journal of orthopaedic surgery and research.
2022 May; 17(1):290. doi:
10.1186/s13018-022-03178-2. [PMID: 35619183] - Valentin Lacombe, Guy Lenaers, Geoffrey Urbanski. Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins' Synthesis in Solid Cancers.
Nutrients.
2022 May; 14(10):. doi:
10.3390/nu14102058. [PMID: 35631199] - Adela Čorejová, Tomáš Fazekaš, Daniela Jánošíková, Juraj Repiský, Veronika Pospíšilová, Maria Miková, Drahomíra Rauová, Daniela Ostatníková, Ján Kyselovič, Anna Hrabovská. Improvement of the Clinical and Psychological Profile of Patients with Autism after Methylcobalamin Syrup Administration.
Nutrients.
2022 May; 14(10):. doi:
10.3390/nu14102035. [PMID: 35631176] - Odunayo Ifeoluwa Sobowale, Moududur Rahman Khan, Anjan Kumar Roy, Rubhana Raqib, Faruk Ahmed. Prevalence and Risk Factors of Vitamin B12 Deficiency among Pregnant Women in Rural Bangladesh.
Nutrients.
2022 May; 14(10):. doi:
10.3390/nu14101993. [PMID: 35631134] - Tesfaye Madebo, Mitra Bemanian, Jørn Henrik Vold, Ranadip Chowdhury, Christer Frode Aas, Karl Trygve Druckrey-Fiskaaen, Kjell Arne Johansson, Lars Thore Fadnes. Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway.
Nutrients.
2022 May; 14(9):. doi:
10.3390/nu14091941. [PMID: 35565908] - Srivats S Narayanan, Madhavi Murali, Jacob C Lucas, Kevin J Sykes. Micronutrients in tinnitus: A National Health and Nutrition Examination Survey analysis.
American journal of otolaryngology.
2022 May; 43(3):103460. doi:
10.1016/j.amjoto.2022.103460. [PMID: 35429847] - Edouard Berling, Guillaume Fargeot, Karine Aure, Tuan Huy Tran, Nathalie Kubis, Pierre Lozeron, Adrien Zanin. Nitrous oxide-induced predominantly motor neuropathies: a follow-up study.
Journal of neurology.
2022 May; 269(5):2720-2726. doi:
10.1007/s00415-021-10858-2. [PMID: 34741241] - Dimitrios Kazantzis, Panagiotis Theodossiadis, Christos Kroupis, George Theodossiadis, Irini Chatziralli. Vitamin B12 and Folate as Risk Factors for Retinal Vein Occlusion: A Meta-Analysis.
Klinische Monatsblatter fur Augenheilkunde.
2022 May; 239(5):709-716. doi:
10.1055/a-1473-5897. [PMID: 34000749] - Michel Boutin, Nancy Presse, David Allard, Tristan Martineau, Pierrette Gaudreau, Christiane Auray-Blais. Methylmalonic acid analysis using urine filter paper samples to screen for metabolic vitamin B12 deficiency in older adults.
Bioanalysis.
2022 May; 14(9):615-626. doi:
10.4155/bio-2022-0007. [PMID: 35546317]