Chlorofluoromethane (BioDeep_00000012786)

 

Secondary id: BioDeep_00001868574

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


chloro(fluoro)methane

化学式: CH2ClF (67.98290539999999)
中文名称: 氯氟甲烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(F)Cl
InChI: InChI=1S/CH2ClF/c2-1-3/h1H2

描述信息

同义名列表

5 个代谢物同义名

chloro(fluoro)methane; Fluorochloromethane; CHLOROFLUOROMETHANE; Chlorofluoromethane; Chlorofluoromethane



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ole D Wolthers, Ewan G Walters. Short-term lower leg growth in 5- to 11-year-old asthmatic children using beclomethasone dipropionate inhalers with chlorofluorocarbon or hydrofluoroalkane propellants: a 9-week, open-label, randomized, crossover, noninferiority study. Clinical therapeutics. 2011 Aug; 33(8):1069-76. doi: 10.1016/j.clinthera.2011.06.015. [PMID: 21784529]
  • Karine L Clearie, Peter A Williamson, Karen Meldrum, Michael Gillen, Lars-Goran Carlsson, Marie Carlholm, Jan Ekelund, Brian J Lipworth. Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide. British journal of clinical pharmacology. 2011 Apr; 71(4):504-13. doi: 10.1111/j.1365-2125.2010.03857.x. [PMID: 21395643]
  • Jonathan Baillie. 'Virgin gas' ban demands user rethink. Health estate. 2010 May; 64(5):43-6. doi: ". [PMID: 20527592]
  • Laila M E Sabik, Reem A Abbas, Mahmoud M Ismail, Safwat El-Refaei. Cardiotoxicity of Freon among refrigeration services workers: comparative cross-sectional study. Environmental health : a global access science source. 2009 Jul; 8(?):31. doi: 10.1186/1476-069x-8-31. [PMID: 19594908]
  • Jean Bousquet, Gianluigi Poli, Daniela Acerbi, Raffaella Monno, Steven Ramael, Fabrice Nollevaux. Systemic exposure and implications for lung deposition with an extra-fine hydrofluoroalkane beclometasone dipropionate/formoterol fixed combination. Clinical pharmacokinetics. 2009; 48(6):347-58. doi: 10.2165/00003088-200948060-00001. [PMID: 19650674]
  • C Main, J Shepherd, R Anderson, G Rogers, J Thompson-Coon, Z Liu, D Hartwell, E Loveman, C Green, M Pitt, K Stein, P Harris, G K Frampton, M Smith, A Takeda, A Price, K Welch, M Somerville. Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in children under the age of 12 years. Health technology assessment (Winchester, England). 2008 May; 12(20):1-174, iii. doi: 10.3310/hta12200. [PMID: 18485272]
  • Kenneth T Kim, Henry Milgrom, Y Kellie Yoon, Arden L Levy, Paul Matz, Michael J Welch, Anthony Cahn, David A Collins, Steven Kathman, Rashmi Mehta, Sheng-Fang Su, Robert L Kunka. Systemic exposure and urinary cortisol effects of fluticasone propionate formulated with hydrofluoroalkane in 4- to 11-year-olds with asthma. Journal of clinical pharmacology. 2008 Jan; 48(1):108-16. doi: 10.1177/0091270007309704. [PMID: 18094223]
  • William R Lumry, Michael M Conway, Craig F LaForce, David S Pearlman, Catherine A Scott, Nancy E Herje, Wei W Wu, Courtney Crim. Fluticasone propionate hydrofluoroalkane inhalation aerosol in patients receiving inhaled corticosteroids. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2006 Jan; 96(1):51-9. doi: 10.1016/s1081-1206(10)61040-x. [PMID: 16440533]
  • George P Chrousos, Lisa Ghaly, Arthur Shedden, Domenic G Iezzoni, Alan G Harris. Effects of mometasone furoate dry powder inhaler and beclomethasone dipropionate hydrofluoroalkane and chlorofluorocarbon on the hypothalamic-pituitary-adrenal axis in asthmatic subjects. Chest. 2005 Jul; 128(1):70-7. doi: 10.1378/chest.128.1.70. [PMID: 16002918]
  • Matthias Freiwald, Anagnostis Valotis, Andreas Kirschbaum, Monika McClellan, Thomas Mürdter, Peter Fritz, Godehard Friedel, Michael Thomas, Petra Högger. Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model. Respiratory research. 2005 Feb; 6(?):21. doi: 10.1186/1465-9921-6-21. [PMID: 15727687]
  • C M Houghton, S J Langley, S D Singh, J Holden, A P Monici Preti, D Acerbi, G Poli, A Woodcock. Comparison of bronchoprotective and bronchodilator effects of a single dose of formoterol delivered by hydrofluoroalkane and chlorofluorocarbon aerosols and dry powder in a double blind, placebo-controlled, crossover study. British journal of clinical pharmacology. 2004 Oct; 58(4):359-66. doi: 10.1111/j.1365-2125.2004.02172.x. [PMID: 15373928]
  • Louis-Philippe Boulet, André Cartier, Pierre Ernst, Pierre Larivée, Michel Laviolette. Safety and efficacy of HFA-134a beclomethasone dipropionate extra-fine aerosol over six months. Canadian respiratory journal. 2004 Mar; 11(2):123-30. doi: 10.1155/2004/823084. [PMID: 15045043]
  • S P Vyas, M E Kannan, Sanyog Jain, V Mishra, Paramjit Singh. Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages. International journal of pharmaceutics. 2004 Jan; 269(1):37-49. doi: 10.1016/j.ijpharm.2003.08.017. [PMID: 14698575]
  • Silvia Bortolato, Alberta Zanovello, Massimo Rugge, Maurizio Brotto, Sandra Marini, Pier Giovanni Gervasi, Maurizio Manno. Trifluoroacetylated proteins in liver and plasma of guinea pigs treated with HCFC-123 and halothane. Toxicology letters. 2003 Sep; 144(1):35-47. doi: 10.1016/s0378-4274(03)00228-5. [PMID: 12919722]
  • Vijay Joguparthi, Philip Breen, Cesar Compadre, Xiang Zhou, Larry Gann, F Charles Hiller, Paula Anderson. Effect of propellant on the pharmacokinetics and pharmacodynamics of inhaled albuterol in asthmatic subjects. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 2003; 16(1):47-53. doi: 10.1089/089426803764928356. [PMID: 12737684]
  • Anjuli Nayak, Robert Lanier, Steven Weinstein, Patti Stampone, Michael Welch. Efficacy and safety of beclomethasone dipropionate extrafine aerosol in childhood asthma: a 12-week, randomized, double-blind, placebo-controlled study. Chest. 2002 Dec; 122(6):1956-65. doi: 10.1378/chest.122.6.1956. [PMID: 12475833]
  • V Vondra, K Sladek, J Kotasová, M Terl, A Rossetti, L Cantini. A new HFA-134a propellant in the administration of inhaled BDP via the Jet spacer: controlled clinical trial vs the conventional CFC. Respiratory medicine. 2002 Oct; 96(10):784-9. doi: 10.1053/rmed.2002.1348. [PMID: 12412977]
  • Arno Nolting, Wattanaporn Abramowitz. Multiple-dose proportionality study of flunisolide hydrofluoroalkane. Allergy and asthma proceedings. 2002 Sep; 23(5):311-8. doi: NULL. [PMID: 12476540]
  • J Bousquet, L Cantini. Clinical studies in asthmatics with a new non-extra fine HFA formulation of beclometasone dipropionate (BDP Modulite). Respiratory medicine. 2002 Aug; 96 Suppl D(?):S17-27. doi: 10.1016/s0954-6111(02)80020-8. [PMID: 12201078]
  • Stanley J Szefler, Richard J Martin, Tonya Sharp King, Homer A Boushey, Reuben M Cherniack, Vernon M Chinchilli, Timothy J Craig, Myrna Dolovich, Jeffrey M Drazen, Joanne K Fagan, John V Fahy, James E Fish, Jean G Ford, Elliot Israel, James Kiley, Monica Kraft, Stephen C Lazarus, Robert F Lemanske, Elizabeth Mauger, Stephen P Peters, Christine A Sorkness. Significant variability in response to inhaled corticosteroids for persistent asthma. The Journal of allergy and clinical immunology. 2002 Mar; 109(3):410-8. doi: 10.1067/mai.2002.122635. [PMID: 11897984]
  • Arno Nolting, Suryanarayana Sista, Wattanaporn Abramowitz. Single-dose study to compare the pharmacokinetics of HFA flunisolide and CFC flunisolide. Journal of pharmaceutical sciences. 2002 Feb; 91(2):424-32. doi: 10.1002/jps.10030. [PMID: 11835202]
  • A Nolting, S Sista, W Abramowitz. Flunisolide HFA vs flunisolide CFC: pharmacokinetic comparison in healthy volunteers. Biopharmaceutics & drug disposition. 2001 Dec; 22(9):373-82. doi: 10.1002/bdd.274. [PMID: 11870676]
  • P Fireman, B M Prenner, W Vincken, M Demedts, S J Mol, R M Cohen. Long-term safety and efficacy of a chlorofluorocarbon-free beclomethasone dipropionate extrafine aerosol. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2001 May; 86(5):557-65. doi: 10.1016/s1081-1206(10)62905-5. [PMID: 11379808]
  • E D Bateman, V Silins, M Bogolubov. Clinical equivalence of salmeterol/fluticasone propionate in combination (50/100 microg twice daily) when administered via a chlorofluorocarbon-free metered dose inhaler or dry powder inhaler to patients with mild-to-moderate asthma. Respiratory medicine. 2001 Feb; 95(2):136-46. doi: 10.1053/rmed.2000.1008. [PMID: 11217910]
  • J Richards, P Hirst, G Pitcairn, S Mahashabde, W Abramowitz, A Nolting, S P Newman. Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 2001; 14(2):197-208. doi: 10.1089/08942680152484126. [PMID: 11681651]