OCTACHLORODIBENZO-p-DIOXIN (BioDeep_00000012130)

 

Secondary id: BioDeep_00001868165

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


octachlorodibenzo-4-Dioxin, 13C-labeled CPD

化学式: C12Cl8O2 (455.740654)
中文名称: 1,2,3,4,6,7,8,9-八氯二苯并-对-二恶英
谱图信息: 最多检出来源 Homo sapiens(blood) 83.33%

分子结构信息

SMILES: C12=C(C(=C(C(=C1Cl)Cl)Cl)Cl)OC3=C(O2)C(=C(C(=C3Cl)Cl)Cl)Cl
InChI: InChI=1S/C12Cl8O2/c13-1-2(14)6(18)10-9(5(1)17)21-11-7(19)3(15)4(16)8(20)12(11)22-10

描述信息

D009676 - Noxae > D013723 - Teratogens > D000072317 - Polychlorinated Dibenzodioxins

同义名列表

9 个代谢物同义名

octachlorodibenzo-4-Dioxin, 13C-labeled CPD; 1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin; OCTACHLORODIBENZO-p-DIOXIN; octachlorodibenzo-4-Dioxin; octachlorodibenzodioxin; Octachlorooxanthrene; PCDD 75; OCDD; 1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yin-Hui Leong, Nurul Izzati Azmi, Mohamed Isa Abdul Majid, Sheng Wen. Exposure and risk assessment of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dl-PCBs) for primiparous mothers and breastfed infants in Penang, Malaysia. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2021 Aug; 38(8):1416-1426. doi: 10.1080/19440049.2021.1922758. [PMID: 34014804]
  • Duk-Hee Lee, P Monica Lind, David R Jacobs, Samira Salihovic, Bert van Bavel, Lars Lind. Background exposure to persistent organic pollutants predicts stroke in the elderly. Environment international. 2012 Oct; 47(?):115-20. doi: 10.1016/j.envint.2012.06.009. [PMID: 22809777]
  • Lisa A Rodenburg, Songyan Du, Hui Lui, Jia Guo, Nicole Oseagulu, Donna E Fennell. Evidence for dechlorination of polychlorinated biphenyls and polychlorinated dibenzo-p-dioxins and -furans in wastewater collection systems in the New York metropolitan area. Environmental science & technology. 2012 Jun; 46(12):6612-20. doi: 10.1021/es300560q. [PMID: 22568653]
  • Monika Rönn, Lars Lind, Bert van Bavel, Samira Salihovic, Karl Michaëlsson, Pia Monica Lind. Circulating levels of persistent organic pollutants associate in divergent ways to fat mass measured by DXA in humans. Chemosphere. 2011 Oct; 85(3):335-43. doi: 10.1016/j.chemosphere.2011.06.095. [PMID: 21767864]
  • Hirokazu Uemura, Kokichi Arisawa, Mineyoshi Hiyoshi, Atsushi Kitayama, Hidenobu Takami, Fusakazu Sawachika, Satoru Dakeshita, Kentaro Nii, Hiroshi Satoh, Yoshio Sumiyoshi, Kenji Morinaga, Kazunori Kodama, Taka-ichiro Suzuki, Masaki Nagai, Tsuguyoshi Suzuki. Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population. Environmental health perspectives. 2009 Apr; 117(4):568-73. doi: 10.1289/ehp.0800012. [PMID: 19440495]
  • Makoto Hirako. Transfer and accumulation of persistent organochlorine compounds from bovine dams to newborn and suckling calves. Journal of agricultural and food chemistry. 2008 Aug; 56(15):6768-74. doi: 10.1021/jf8010118. [PMID: 18616264]
  • John E Elliott, Daniel A Guertin, Jennifer M E Balke. Chlorinated hydrocarbon contaminants in feces of river otters from the southern Pacific coast of Canada, 1998-2004. The Science of the total environment. 2008 Jul; 397(1-3):58-71. doi: 10.1016/j.scitotenv.2008.01.063. [PMID: 18433835]
  • Takashi Todaka, Hironori Hirakawa, Jumboku Kajiwara, Tsuguhide Hori, Kazuhiro Tobiishi, Daisuke Onozuka, Shizue Kato, Seiko Sasaki, Sonomi Nakajima, Yasuaki Saijo, Fumihiro Sata, Reiko Kishi, Takao Iida, Masutaka Furue. Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood and breast milk collected from 60 mothers in Sapporo City, Japan. Chemosphere. 2008 Jul; 72(8):1152-8. doi: 10.1016/j.chemosphere.2008.03.050. [PMID: 18474391]
  • Duk-Hee Lee, David R Jacobs, Miquel Porta. Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder. Journal of epidemiology and community health. 2007 Jul; 61(7):591-6. doi: 10.1136/jech.2006.054700. [PMID: 17568050]
  • James Dahlgren, Harpreet Takhar, Arnold Schecter, Reynold Schmidt, Randy Horsak, Olaf Paepke, Raphael Warshaw, Alexander Lee, Pamela Anderson-Mahoney. Residential and biological exposure assessment of chemicals from a wood treatment plant. Chemosphere. 2007 Apr; 67(9):S279-85. doi: 10.1016/j.chemosphere.2006.05.109. [PMID: 17234249]
  • Duk-Hee Lee, In-Kyu Lee, Kyungeun Song, Michael Steffes, William Toscano, Beth A Baker, David R Jacobs. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes care. 2006 Jul; 29(7):1638-44. doi: 10.2337/dc06-0543. [PMID: 16801591]
  • Mary S Wolff, Susan L Teitelbaum, Paul J Lioy, Regina M Santella, Richard Y Wang, Robert L Jones, Kathleen L Caldwell, Andreas Sjödin, Wayman E Turner, Wei Li, Panos Georgopoulos, Gertrud S Berkowitz. Exposures among pregnant women near the World Trade Center site on 11 September 2001. Environmental health perspectives. 2005 Jun; 113(6):739-48. doi: 10.1289/ehp.7694. [PMID: 15929898]
  • Shinji Kumagai, Hajime Oda, Takeo Tabuchi, Susumu Akasaka, Hiroshi Kosaka, Jin Yoshida, Shigeki Koda, Ippei Mouri. [Relationships between dioxin concentrations in deposited dust and those in serum of workers at municipal waste incineration plants]. Sangyo eiseigaku zasshi = Journal of occupational health. 2004 Jan; 46(1):1-9. doi: 10.1539/sangyoeisei.46.1. [PMID: 15024837]
  • James Dahlgren, Raphael Warshaw, Randy D Horsak, Frank M Parker, Harpreet Takhar. Exposure assessment of residents living near a wood treatment plant. Environmental research. 2003 Jun; 92(2):99-109. doi: 10.1016/s0013-9351(02)00064-6. [PMID: 12854689]
  • G Andreas Moser, Michael S McLachlan. Modeling digestive tract absorption and desorption of lipophilic organic contaminants in humans. Environmental science & technology. 2002 Aug; 36(15):3318-25. doi: 10.1021/es015853l. [PMID: 12188360]
  • S Kumagai, S Koda, T Miyakita, M Ueno. Polychlorinated dibenzo-p-dioxin and dibenzofuran concentrations in serum samples of workers at intermittently burning municipal waste incinerators in Japan. Occupational and environmental medicine. 2002 Jun; 59(6):362-8. doi: 10.1136/oem.59.6.362. [PMID: 12040109]
  • P Isosaari, T Tuhkanen, T Vartiainen. Use of olive oil for soil extraction and ultraviolet degradation of polychlorinated dibenzo-p-dioxins and dibenzofurans. Environmental science & technology. 2001 Mar; 35(6):1259-65. doi: 10.1021/es000190d. [PMID: 11347942]
  • H L Keller, D C Borger, L B Willett. Uptake and excretion of organochlorine compounds in neonatal calves. Journal of animal science. 2001 Jan; 79(1):155-66. doi: 10.2527/2001.791155x. [PMID: 11204696]
  • J K Huwe, V J Feil, R G Zaylskie, T O Tiernan. An investigation of the in vivo formation of octachlorodibenzo-p-dioxin. Chemosphere. 2000 May; 40(9-11):957-62. doi: 10.1016/s0045-6535(99)00339-2. [PMID: 10739032]
  • L Hardell, G Lindström, G Liljegren, P Dahl, A Magnuson. Increased concentrations of octachlorodibenzo-p-dioxin in cases with breast cancer--results from a case-control study. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 1996 Oct; 5(5):351-7. doi: 10.1097/00008469-199610000-00007. [PMID: 8972254]