2,2',3,4,4',5',6-Heptabromodiphenyl ether (BioDeep_00000012108)

 

Secondary id: BioDeep_00001869300

human metabolite


代谢物信息卡片


1,2,3,5-Tetrabromo-4-(2,4,5-tribromophenoxy)-benzene

化学式: C12H3Br7O (715.4467)
中文名称: 2,2,3,4,4,5,6-七溴联苯醚
谱图信息: 最多检出来源 Homo sapiens(not specific) 50%

分子结构信息

SMILES: BrC1=CC(Br)=C(OC2=CC(Br)=C(Br)C=C2Br)C(Br)=C1Br
InChI: InChI=1S/C12H3Br7O/c13-4-1-6(15)9(3-5(4)14)20-12-8(17)2-7(16)10(18)11(12)19/h1-3H

描述信息

2,2,3,4,4,5,6-Heptabromodiphenyl ether is classified as a Food Contaminant (code WG) in the DFC.
Classified as a Food Contaminant (code WG) in the DFC
D005411 - Flame Retardants

同义名列表

8 个代谢物同义名

1,2,3,5-Tetrabromo-4-(2,4,5-tribromophenoxy)-benzene; 1,2,3,5-Tetrabromo-4-(2,4,5-tribromophenoxy)benzene; 2,2,3,4,4,5,6-heptabromodiphenyl ether; 2,2,3,4,4,5,6-HeptaBDE; PBDE 183; BDE 183; BDE-183; 2,2',3,4,4',5',6-Heptabromodiphenyl ether



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ling-Chuan Guo, Shengbing Yu, De Wu, Jinxu Huang, Tao Liu, Jianpeng Xiao, Weixiong Huang, Yanhong Gao, Xing Li, Weilin Zeng, Shannon Rutherford, Wenjun Ma, Yonghui Zhang, Lifeng Lin. Disruption of thyroid hormone regulated proteins and gene expression by polychlorinated biphenyls, polybrominated diphenyl ethers and new flame retardants in residents of an e-waste region. Environmental pollution (Barking, Essex : 1987). 2019 Nov; 254(Pt B):112925. doi: 10.1016/j.envpol.2019.07.093. [PMID: 31454572]
  • E Bizkarguenaga, A Iparraguirre, E Oliva, J B Quintana, R Rodil, L A Fernández, O Zuloaga, A Prieto. Uptake of polybrominated diphenyl ethers by carrot and lettuce crops grown in compost-amended soils. Environmental science and pollution research international. 2016 Feb; 23(4):3847-59. doi: 10.1007/s11356-015-5608-y. [PMID: 26498966]
  • Shirley Poon, Michael G Wade, Katarina Aleksa, Dorothea F K Rawn, Amanda Carnevale, Dean W Gaertner, Amy Sadler, François Breton, Gideon Koren, Sheila R Ernest, Claudia Lalancette, Bernard Robaire, Barbara F Hales, Cynthia G Goodyer. Hair as a biomarker of systemic exposure to polybrominated diphenyl ethers. Environmental science & technology. 2014 Dec; 48(24):14650-8. doi: 10.1021/es502789h. [PMID: 25387207]
  • K H Chiu, C-R Lin, H-W Huang, J Shiea, L L Liu. Toxic effects of two brominated flame retardants BDE-47 and BDE-183 on the survival and protein expression of the tubificid Monopylephorus limosus. Ecotoxicology and environmental safety. 2012 Oct; 84(?):46-53. doi: 10.1016/j.ecoenv.2012.06.022. [PMID: 22818847]
  • E G Sørmo, E Lie, A Ruus, H Gaustad, J U Skaare, B M Jenssen. Trophic level determines levels of brominated flame-retardants in coastal herring gulls. Ecotoxicology and environmental safety. 2011 Oct; 74(7):2091-8. doi: 10.1016/j.ecoenv.2011.06.012. [PMID: 21762987]
  • Jie Xu, Zishen Gao, Qiming Xian, Hongxia Yu, Jianfang Feng. Levels and distribution of polybrominated diphenyl ethers (PBDEs) in the freshwater environment surrounding a PBDE manufacturing plant in China. Environmental pollution (Barking, Essex : 1987). 2009 Jun; 157(6):1911-6. doi: 10.1016/j.envpol.2009.01.030. [PMID: 19233527]
  • Jenny Rattfelt Nyholm, Anna Norman, Leif Norrgren, Peter Haglund, Patrik L Andersson. Maternal transfer of brominated flame retardants in zebrafish (Danio rerio). Chemosphere. 2008 Sep; 73(2):203-8. doi: 10.1016/j.chemosphere.2008.04.033. [PMID: 18514256]
  • Ana Labandeira, Ethel Eljarrat, Damià Barceló. Congener distribution of polybrominated diphenyl ethers in feral carp (Cyprinus carpio) from the Llobregat River, Spain. Environmental pollution (Barking, Essex : 1987). 2007 Mar; 146(1):188-95. doi: 10.1016/j.envpol.2006.04.037. [PMID: 17010488]
  • Timo Hamers, Jorke H Kamstra, Edwin Sonneveld, Albertinka J Murk, Monique H A Kester, Patrik L Andersson, Juliette Legler, Abraham Brouwer. In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. Toxicological sciences : an official journal of the Society of Toxicology. 2006 Jul; 92(1):157-73. doi: 10.1093/toxsci/kfj187. [PMID: 16601080]
  • V L B Jaspers, A Covaci, S Voorspoels, T Dauwe, M Eens, P Schepens. Brominated flame retardants and organochlorine pollutants in aquatic and terrestrial predatory birds of Belgium: levels, patterns, tissue distribution and condition factors. Environmental pollution (Barking, Essex : 1987). 2006 Jan; 139(2):340-52. doi: 10.1016/j.envpol.2005.05.008. [PMID: 16005130]
  • Jae-Won Choi, T Susumu Fujimaki, Kimiyoshi Kitamura, Shunji Hashimoto, Hiroyasu Ito, Noriyuki Suzuki, Shin-ichi Sakai, Masatoshi Morita. Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue. Environmental science & technology. 2003 Mar; 37(5):817-21. doi: 10.1021/es0258780. [PMID: 12666907]
  • A Sjödin, D G Patterson, A Bergman. Brominated flame retardants in serum from U.S. blood donors. Environmental science & technology. 2001 Oct; 35(19):3830-3. doi: 10.1021/es010815n. [PMID: 11642440]
  • C Thomsen, E Lundanes, G Becher. Brominated flame retardants in plasma samples from three different occupational groups in Norway. Journal of environmental monitoring : JEM. 2001 Aug; 3(4):366-70. doi: 10.1039/b104304h. [PMID: 11523435]