Tifluadom (BioDeep_00000008879)
Secondary id: BioDeep_00001876710
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C22H20FN3OS (393.13110420000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C(CN=C(C2=CC=CC=C21)C3=CC=CC=C3F)CNC(=O)C4=CSC=C4
InChI: InChI=1S/C22H20FN3OS/c1-26-16(13-25-22(27)15-10-11-28-14-15)12-24-21(17-6-2-4-8-19(17)23)18-7-3-5-9-20(18)26/h2-11,14,16H,12-13H2,1H3,(H,25,27)
描述信息
C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D045283 - Natriuretic Agents > D004232 - Diuretics
Same as: D02694
同义名列表
6 个代谢物同义名
N-{[5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl}thiophene-3-carboximidate; N-{[5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl}thiophene-3-carboxamide; 1-Methyl-2-(3-thienylcarbonyl)aminomethyl-5-(2-fluorophenyl)-H-2,3-dihydro-1,4-benzodiazepine; Titfluadom; Tifluadom; Tifluadom
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:9591
- KEGG: C11797
- PubChem: 115208
- HMDB: HMDB0259086
- Metlin: METLIN69227
- ChEMBL: CHEMBL169703
- chemspider: 103084
- CAS: 83386-35-0
- CAS: 81656-30-6
- PMhub: MS000022583
- PubChem: 13961
- NIKKAJI: J33.075B
- RefMet: Tifluadom
- KNApSAcK: 9591
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- C D Soulard, S Guerif, A Payne, S G Dahl. Differential effects of fedotozine compared to other kappa agonists on diuresis in rats.
The Journal of pharmacology and experimental therapeutics.
1996 Dec; 279(3):1379-85. doi:
. [PMID: 8968362] - R M Craft, L A Dykstra. Agonist and antagonist activity of kappa opioids in the squirrel monkey: I. Antinociception and urine output.
The Journal of pharmacology and experimental therapeutics.
1992 Jan; 260(1):327-33. doi:
. [PMID: 1309876] - K R Borkowski. Studies on the adrenomedullary dependence of kappa-opioid agonist-induced diuresis in conscious rats.
British journal of pharmacology.
1989 Dec; 98(4):1151-6. doi:
10.1111/j.1476-5381.1989.tb12659.x. [PMID: 2558758] - H C Jackson, I Kitchen. Effects of opioid agonists on urine production in neonatal rats.
The Journal of pharmacy and pharmacology.
1989 Apr; 41(4):281-3. doi:
10.1111/j.2042-7158.1989.tb06455.x. [PMID: 2568475] - H Ureta, L F López, A Pérez, J P Huidobro-Toro. Kappa-opiate-induced diuresis and changes in blood pressure: demonstration of receptor stereoselectivity using (+)- and (-)-tifluadom.
European journal of pharmacology.
1987 Mar; 135(3):289-95. doi:
10.1016/0014-2999(87)90677-7. [PMID: 3034631] - T P Blackburn, K R Borkowski, J Friend, M J Rance. On the mechanisms of kappa-opioid-induced diuresis.
British journal of pharmacology.
1986 Nov; 89(3):593-8. doi:
10.1111/j.1476-5381.1986.tb11160.x. [PMID: 3542107] - A G Hayes, B R Stewart. Effect of mu and kappa opioid receptor agonists on rat plasma corticosterone levels.
European journal of pharmacology.
1985 Oct; 116(1-2):75-9. doi:
10.1016/0014-2999(85)90186-4. [PMID: 2996912]