Sativan (BioDeep_00000008135)

human metabolite PANOMIX_OTCML-2023 Endogenous

代谢物信息卡片

3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol

化学式: C17H18O4 (286.1205028)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 0.38%

分子结构信息

SMILES: C1(O)=CC2OC[C@@]([H])(C3=CC=C(OC)C=C3OC)CC=2C=C1
InChI: InChI=1S/C17H18O4/c1-19-14-5-6-15(17(9-14)20-2)12-7-11-3-4-13(18)8-16(11)21-10-12/h3-6,8-9,12,18H,7,10H2,1-2H3

描述信息

Sativan, also known as sativin or (-)-sativan, is a member of the class of compounds known as 4-o-methylated isoflavonoids. 4-o-methylated isoflavonoids are isoflavonoids with methoxy groups attached to the C4 atom of the isoflavonoid backbone. Isoflavonoids are natural products derived from 3-phenylchromen-4-one. Sativan is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Sativan can be found in pulses, which makes sativan a potential biomarker for the consumption of this food product.
Sativan is found in pulses. Phytoalexin of Medicago species, Trifolium species and Trigonella specie

同义名列表

7 个代谢物同义名

3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol; 7-Hydroxy-2,4-dimethoxyisoflavan; 2-O-Methylvestitol; Sativin (alfalfa); (-)-Sativan; Sativan; Sativin

数据库引用编号

17 个数据库交叉引用编号

ChEBI: CHEBI:115
KEGG: C10526
PubChem: 596401
PubChem: 170570
HMDB: HMDB0030521
Metlin: METLIN48270
LipidMAPS: LMPK12080025
MetaCyc: CPD-9367
KNApSAcK: C00002570
foodb: FDB030084
chemspider: 518443
CAS: 41743-86-6
CAS: 71831-00-0
PMhub: MS000021696
PubChem: 12709
3DMET: B03927
NIKKAJI: J451.759H

分类词条

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(3)

vestitol and sativan biosynthesis: (-)-medicarpin + H⁺ + NADPH ⟶ (-)-vestitol + NADP⁺
vestitol and sativan biosynthesis: (-)-medicarpin + H⁺ + NADPH ⟶ (-)-vestitol + NADP⁺
vestitol and sativan biosynthesis: (-)-medicarpin + H⁺ + NADPH ⟶ (-)-vestitol + NADP⁺

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

162666 - Baphia nitida: 10.1016/0031-9422(92)80205-S
390503 - Caragana tibetica: 10.1248/CPB.53.1204
500182 - Centrolobium tomentosum: 10.1016/S0031-9422(00)97984-6
1954552 - Deguelia amazonica: 10.1016/S0031-9422(00)98664-3
47101 - Galega officinalis: 10.1016/S0024-3205(00)00435-5
167663 - Gliricidia sepium: 10.1021/NP980002L
9606 - Homo sapiens: -
47247 - Lotus corniculatus: 10.1016/S0031-9422(00)94374-7
3877 - Medicago: 10.1038/242125A0
3879 - Medicago sativa: 10.1021/NP50063A026
455371 - Spatholobus suberectus: 10.3184/174751918X15386515371813
185975 - Wisteria brachybotrys: 10.1248/BPB.20.865

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Hyung-In Moon, Eun Ju Kim, Joongku Lee, Hyeong-Kyu Lee, Jin Ho Chung. The effect of sativan from Viola verecunda A. Gray on the expressions of matrix metalloproteinase-1 caused by ultraviolet irradiated cultured primary human skin fibroblasts. Journal of ethnopharmacology. 2006 Mar; 104(1-2):12-7. doi: 10.1016/j.jep.2005.08.060. [PMID: 16207520]
J C Le Bail, Y Champavier, A J Chulia, G Habrioux. Effects of phytoestrogens on aromatase, 3beta and 17beta-hydroxysteroid dehydrogenase activities and human breast cancer cells. Life sciences. 2000 Feb; 66(14):1281-91. doi: 10.1016/s0024-3205(00)00435-5. [PMID: 10755463]