2-Keto-3-deoxy-D-gluconic acid (BioDeep_00000004396)

 

Secondary id: BioDeep_00000014414, BioDeep_00001869094

human metabolite PANOMIX_OTCML-2023 Endogenous Volatile Flavor Compounds


代谢物信息卡片


4,5,6-trihydroxy-2-oxohexanoic acid

化学式: C6H10O6 (178.04773600000001)
中文名称: 2-酮-3-脱氧-d-葡萄糖酸
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 0.26%

分子结构信息

SMILES: C(C(C(CO)O)O)C(=O)C(=O)O
InChI: InChI=1S/C6H10O6/c7-2-5(10)3(8)1-4(9)6(11)12/h3,5,7-8,10H,1-2H2,(H,11,12)/t3-,5+/m0/s1

描述信息

同义名列表

7 个代谢物同义名

4,5,6-trihydroxy-2-oxohexanoic acid; 2-Keto-3-deoxy-D-gluconic acid; 2-Dehydro-3-deoxy-D-gluconate; 2-Keto-3-deoxy-D-gluconate; 2-Keto-3-deoxygluconate; 2-Keto-3-deoxy-D-gluconic acid; 2-Dehydro-3-deoxy-D-gluconate



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Joanne K Hobbs, Seunghyae M Lee, Melissa Robb, Fraser Hof, Christopher Barr, Kento T Abe, Jan-Hendrik Hehemann, Richard McLean, D Wade Abbott, Alisdair B Boraston. KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America. 2016 May; 113(22):6188-93. doi: 10.1073/pnas.1524214113. [PMID: 27185956]
  • Pengfei He, Kun Hao, Jochen Blom, Christian Rückert, Joachim Vater, Zichao Mao, Yixin Wu, Mingsheng Hou, Pengbo He, Yueqiu He, Rainer Borriss. Genome sequence of the plant growth promoting strain Bacillus amyloliquefaciens subsp. plantarum B9601-Y2 and expression of mersacidin and other secondary metabolites. Journal of biotechnology. 2012 Dec; 164(2):281-91. doi: 10.1016/j.jbiotec.2012.12.014. [PMID: 23357245]
  • Wilfred D Kepseu, Jacques-Alexandre Sepulchre, Sylvie Reverchon, William Nasser. Toward a quantitative modeling of the synthesis of the pectate lyases, essential virulence factors in Dickeya dadantii. The Journal of biological chemistry. 2010 Sep; 285(37):28565-76. doi: 10.1074/jbc.m110.114710. [PMID: 20581112]
  • François Collard, Didier Vertommen, Juliette Fortpied, Gregg Duester, Emile Van Schaftingen. Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1). Biochimie. 2007 Mar; 89(3):369-73. doi: 10.1016/j.biochi.2006.11.005. [PMID: 17175089]
  • Thierry Franza, Isabelle Michaud-Soret, Pierrette Piquerel, Dominique Expert. Coupling of iron assimilation and pectinolysis in Erwinia chrysanthemi 3937. Molecular plant-microbe interactions : MPMI. 2002 Nov; 15(11):1181-91. doi: 10.1094/mpmi.2002.15.11.1181. [PMID: 12423024]
  • V James, N Hugouvieux-Cotte-Pattat. Regulatory systems modulating the transcription of the pectinase genes of Erwinia chrysanthemi are conserved in Escherichia coli. Microbiology (Reading, England). 1996 Sep; 142 ( Pt 9)(?):2613-9. doi: 10.1099/00221287-142-9-2613. [PMID: 8828230]
  • E Fujii, H Iwase, I Ishii-Karakasa, Y Yajima, K Hotta. The presence of 2-keto-3-deoxygluconic acid and oxoaldehyde dehydrogenase activity in human erythrocytes. Biochemical and biophysical research communications. 1995 May; 210(3):852-7. doi: 10.1006/bbrc.1995.1736. [PMID: 7763257]
  • W Nasser, S Reverchon, J Robert-Baudouy. Purification and functional characterization of the KdgR protein, a major repressor of pectinolysis genes of Erwinia chrysanthemi. Molecular microbiology. 1992 Jan; 6(2):257-65. doi: 10.1111/j.1365-2958.1992.tb02007.x. [PMID: 1545709]