Psilocybine (BioDeep_00000002567)
Secondary id: BioDeep_00001867947
human metabolite blood metabolite
代谢物信息卡片
3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol dihydrogen phosphoric acid ester
化学式: C12H17N2O4P (284.0925892)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 0.69%
分子结构信息
SMILES: CN(C)CCC1=CNC2=C1C(=CC=C2)OP(=O)(O)O
InChI: InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)
描述信息
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D006213 - Hallucinogens
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
15 个代谢物同义名
3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol dihydrogen phosphoric acid ester; 3-(2-(Dimethylamino)ethyl)-1H-indol-4-ol dihydrogen phosphate ester; ({3-[2-(dimethylamino)ethyl]-1H-indol-4-yl}oxy)phosphonic acid; 3-(2-Dimethylaminoethyl)indol-4-yl dihydrogen phosphoric acid; 3-(2-Dimethylaminoethyl)indol-4-yl dihydrogen phosphate; O-Phosphoryl-4-hydroxy-N,N-dimethyltryptamine; 4-Phosphoryloxy-N,N-dimethyltryptamine; Psilocin phosphoric acid ester; Psilocin phosphate ester; Psilocybinum; Psilocibina; Psilocybine; Psilocibin; Psilocybin; Indocybin
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:8614
- KEGG: C07576
- PubChem: 10624
- HMDB: HMDB0256899
- Metlin: METLIN66689
- DrugBank: DB11664
- ChEMBL: CHEMBL194378
- Wikipedia: Psilocybin
- MeSH: Psilocybin
- KNApSAcK: C00051822
- chemspider: 10178
- CAS: 520-52-5
- PMhub: MS000003974
- PubChem: 9779
- PDB-CCD: X8Q
- NIKKAJI: J6.604D
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Esmaeel Ghasemi Gojani, Bo Wang, Dong-Ping Li, Olga Kovalchuk, Igor Kovalchuk. The Impact of Psilocybin on High Glucose/Lipid-Induced Changes in INS-1 Cell Viability and Dedifferentiation.
Genes.
2024 Jan; 15(2):. doi:
10.3390/genes15020183. [PMID: 38397173] - Alistair R McTaggart, Stephen McLaughlin, Jason C Slot, Kevin McKernan, Chris Appleyard, Tia L Bartlett, Matthew Weinert, Caine Barlow, Leon N Warne, Louise S Shuey, André Drenth, Timothy Y James. Domestication through clandestine cultivation constrained genetic diversity in magic mushrooms relative to naturalized populations.
Current biology : CB.
2023 12; 33(23):5147-5159.e7. doi:
10.1016/j.cub.2023.10.059. [PMID: 38052161] - Marco Pepe, Mohsen Hesami, Karla A de la Cerda, Melissa L Perreault, Tom Hsiang, Andrew Maxwell Phineas Jones. A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond.
Biotechnology advances.
2023 12; 69(?):108247. doi:
10.1016/j.biotechadv.2023.108247. [PMID: 37659744] - Lei-Qi Liu, Jing-Ze Chen, Wu-Sheng Fu, Cui-Ying Tang. [Determination of amanita peptide and tryptamine toxins in wild mushrooms by high performance liquid chromatography-tandem mass spectrometry].
Se pu = Chinese journal of chromatography.
2023 Nov; 41(11):976-985. doi:
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Pharmacological research.
2023 Jun; 194(?):106837. doi:
10.1016/j.phrs.2023.106837. [PMID: 37379962] - Matthew Meyer, Jason Slot. The evolution and ecology of psilocybin in nature.
Fungal genetics and biology : FG & B.
2023 06; 167(?):103812. doi:
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Fungal genetics and biology : FG & B.
2022 Dec; 165(?):103769. doi:
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International journal of environmental research and public health.
2022 05; 19(11):. doi:
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2022 05; 47(6):1180-1187. doi:
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Fungal biology.
2022 04; 126(4):308-319. doi:
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Clinical pharmacology and therapeutics.
2022 04; 111(4):886-895. doi:
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BMJ open.
2021 12; 11(12):e056091. doi:
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European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2021 09; 50(?):121-132. doi:
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Irish journal of psychological medicine.
2021 06; 38(2):93-98. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2021 04; 118(17):. doi:
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Cell reports.
2021 04; 35(4):109040. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2021 Feb; 1164(?):122486. doi:
10.1016/j.jchromb.2020.122486. [PMID: 33485158] - Faez Iqbal Khan, Fakhrul Hassan, Dakun Lai. In Silico Studies on Psilocybin Drug Derivatives Against SARS-CoV-2 and Cytokine Storm of Human Interleukin-6 Receptor.
Frontiers in immunology.
2021; 12(?):794780. doi:
10.3389/fimmu.2021.794780. [PMID: 35095870] - Martin K Madsen, Gitte M Knudsen. Plasma psilocin critically determines behavioral and neurobiological effects of psilocybin.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2021 01; 46(1):257-258. doi:
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European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2021 01; 42(?):1-11. doi:
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Journal of chromatographic science.
2020 Oct; 58(10):985-991. doi:
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Psychopharmacology.
2020 Oct; 237(10):3161-3171. doi:
10.1007/s00213-020-05601-0. [PMID: 32700023] - Janis Fricke, Robert Kargbo, Lars Regestein, Claudius Lenz, Gundela Peschel, Miriam A Rosenbaum, Alexander Sherwood, Dirk Hoffmeister. Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin.
Chemistry (Weinheim an der Bergstrasse, Germany).
2020 Jul; 26(37):8281-8285. doi:
10.1002/chem.202000134. [PMID: 32101345] - Anna Poliwoda, Katarzyna Zielińska, Piotr P Wieczorek. Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis.
Molecules (Basel, Switzerland).
2020 Mar; 25(7):. doi:
10.3390/molecules25071566. [PMID: 32235328] - Christopher B Germann. The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging.
Medical hypotheses.
2020 Jan; 134(?):109406. doi:
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Emma Honyiglo, Angélique Franchi, Nathalie Cartiser, Charline Bottinelli, Anne-Sophie Advenier, Fabien Bévalot, Laurent Fanton. Unpredictable Behavior Under the Influence of 'Magic Mushrooms': A Case Report and Review of the Literature.
Journal of forensic sciences.
2019 Jul; 64(4):1266-1270. doi:
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2019 06; 44(7):1328-1334. doi:
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Lancet (London, England).
2019 05; 393(10185):2023. doi:
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2019 Mar; 37(1):100-106. doi:
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Chembiochem : a European journal of chemical biology.
2018 10; 19(20):2160-2166. doi:
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ACS chemical neuroscience.
2018 10; 9(10):2304-2306. doi:
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Journal of psychopharmacology (Oxford, England).
2018 07; 32(7):770-778. doi:
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Psychopharmacology.
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Clinical pharmacokinetics.
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2014 Nov; 28(11):981-2. doi:
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Forensic science international.
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Scandinavian journal of clinical and laboratory investigation.
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International journal of legal medicine.
2013 May; 127(3):593-601. doi:
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International journal of legal medicine.
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The American journal of emergency medicine.
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Annales Academiae Medicae Stetinensis.
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Journal of analytical toxicology.
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International journal of legal medicine.
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Psychopharmacology.
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Forensic science international.
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Lab on a chip.
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The Journal of pharmacy and pharmacology.
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