Testosterone cypionate (BioDeep_00000001995)
Main id: BioDeep_00000637361
代谢物信息卡片
17-(3-cyclopentyl-1-propionyl)-17beta-hydroxyandrost-4-en-3-one
化学式: C27H40O3 (412.297729)
中文名称: 环戊丙酸睾酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC(=O)C=C1CCC1C2CCC2(C)C(OC(=O)CCC3CCCC3)CCC12
InChI: InChI=1S/C27H40O3/c1-26-15-13-20(28)17-19(26)8-9-21-22-10-11-24(27(22,2)16-14-23(21)26)30-25(29)12-7-18-5-3-4-6-18/h17-18,21-24H,3-16H2,1-2H3/t21-,22-,23-,24-,26-,27-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2360 - Anabolic Steroid
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:9463
- KEGG: C08156
- KEGGdrug: D00957
- PubChem: 441404
- Metlin: METLIN2786
- DrugBank: DB13943
- ChEMBL: CHEMBL1201101
- CAS: 58-20-8
- PMhub: MS000001615
- MetaboLights: MTBLC9463
- PubChem: 10356
- LipidMAPS: LMST02020074
- 3DMET: B02147
- NIKKAJI: J22.726I
- RefMet: Testosterone cypionate
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kadden H Kothmann, Victoria Jacobsen, Emily Laffitte, Corinne Bromfield, Matthew Grizzaffi, Monica Jarboe, Andrea G Braundmeier-Fleming, Janice M Bahr, Romana A Nowak, Annie E Newell-Fugate. Virilizing doses of testosterone decrease circulating insulin levels and differentially regulate insulin signaling in liver and adipose tissue of females.
American journal of physiology. Endocrinology and metabolism.
2021 06; 320(6):E1107-E1118. doi:
10.1152/ajpendo.00281.2020. [PMID: 33900852] - Samuel R Denmeade, Hao Wang, Neeraj Agarwal, David C Smith, Michael T Schweizer, Mark N Stein, Vasileios Assikis, Przemyslaw W Twardowski, Thomas W Flaig, Russell Z Szmulewitz, Jeffrey M Holzbeierlein, Ralph J Hauke, Guru Sonpavde, Jorge A Garcia, Arif Hussain, Oliver Sartor, Shifeng Mao, Harry Cao, Wei Fu, Ting Wang, Rehab Abdallah, Su Jin Lim, Vanessa Bolejack, Channing J Paller, Michael A Carducci, Mark C Markowski, Mario A Eisenberger, Emmanuel S Antonarakis. TRANSFORMER: A Randomized Phase II Study Comparing Bipolar Androgen Therapy Versus Enzalutamide in Asymptomatic Men With Castration-Resistant Metastatic Prostate Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2021 04; 39(12):1371-1382. doi:
10.1200/jco.20.02759. [PMID: 33617303] - Alexander Justin Lin, Thomas Baranski, Deyali Chaterjee, Will Chapman, Gretchen Foltz, Hyun Kim. Androgen-receptor-positive hepatocellular carcinoma in a transgender teenager taking exogenous testosterone.
Lancet (London, England).
2020 07; 396(10245):198. doi:
10.1016/s0140-6736(20)31538-5. [PMID: 32682485] - Teri N Hreha, Christina A Collins, Allyssa L Daugherty, Joy Twentyman, Nitin Paluri, David A Hunstad. TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis.
Physiological reports.
2020 03; 8(6):e14401. doi:
10.14814/phy2.14401. [PMID: 32227630] - Teri N Hreha, Christina A Collins, Allyssa L Daugherty, Jessie M Griffith, Keith A Hruska, David A Hunstad. Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring.
Frontiers in immunology.
2020; 11(?):1641. doi:
10.3389/fimmu.2020.01641. [PMID: 32849562] - Mônica S Campos, João P A Silva, Danilo S Lima, Luis O Regasini, Mara Rúbia Marques, Manoel F Biancardi, Sebastião R Taboga, Fernanda C A Santos. Short-term exposure to chrysin promotes proliferative responses in the ventral male prostate and female prostate of adult gerbils.
International journal of experimental pathology.
2019 06; 100(3):192-201. doi:
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Steroids.
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Cell biology international.
2018 Sep; 42(9):1200-1211. doi:
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2018 Jun; 116(Pt B):360-368. doi:
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Frontiers in bioscience (Elite edition).
2018 03; 10(2):334-343. doi:
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Fitoterapia.
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2018 01; 19(1):76-86. doi:
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2012 Jan; 10(?):5. doi:
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2010 Dec; 91(6):537-45. doi:
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2010 May; 64(6):682-96. doi:
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Analytical and bioanalytical chemistry.
2009 Oct; 395(4):1075-87. doi:
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The American journal of cardiology.
2008 Mar; 101(5):618-24. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2008 Jan; 15(1-2):44-54. doi:
10.1016/j.phymed.2007.11.011. [PMID: 18068966] - S Kahl, T H Elsasser. Exogenous testosterone modulates tumor necrosis factor-alpha and acute phase protein responses to repeated endotoxin challenge in steers.
Domestic animal endocrinology.
2006 Nov; 31(4):301-11. doi:
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Treatments in endocrinology.
2005; 4(5):293-309. doi:
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Clinical calcium.
2004 May; 14(5):710-8. doi:
clica0405710718. [PMID: 15577031] - Ratna Chatterjee, Susan Wood, Hugh H McGarrigle, William R Lees, David J Ralph, Guy H Neild. A novel therapy with testosterone and sildenafil for erectile dysfunction in patients on renal dialysis or after renal transplantation.
The journal of family planning and reproductive health care.
2004 Apr; 30(2):88-90. doi:
10.1783/147118904322995438. [PMID: 15086991] - John L Ubels, Eric Veenstra, Jonathon Ditlev, Kyle Ingersoll. Interactions of testosterone and all-trans retinoic acid in regulation of androgen receptor expression in rat lacrimal gland.
Experimental eye research.
2003 Dec; 77(6):741-8. doi:
10.1016/j.exer.2003.07.006. [PMID: 14609562] - T C Phillips, R E Larsen, J Hernandez, L Strachan, D Samuelson, V M Shille, L F Archbald. Selective control of the estrous cycle of the dog through suppression of estrus and reduction of the length of anestrus.
Theriogenology.
2003 Mar; 59(5-6):1441-8. doi:
10.1016/s0093-691x(02)01183-4. [PMID: 12527090] - Paul J Perry, William R Yates, Richard D Williams, Arnold E Andersen, John H MacIndoe, Brian C Lund, Timothy L Holman. Testosterone therapy in late-life major depression in males.
The Journal of clinical psychiatry.
2002 Dec; 63(12):1096-101. doi:
10.4088/jcp.v63n1202. [PMID: 12523867] - R Chatterjee, P D Kottaridis, H H McGarrigle, D C Linch. Management of erectile dysfunction by combination therapy with testosterone and sildenafil in recipients of high-dose therapy for haematological malignancies.
Bone marrow transplantation.
2002 Apr; 29(7):607-10. doi:
10.1038/sj.bmt.1703421. [PMID: 11979311] - V Dumestre-Toulet, V Cirimele, B Ludes, S Gromb, P Kintz. Hair analysis of seven bodybuilders for anabolic steroids, ephedrine, and clenbuterol.
Journal of forensic sciences.
2002 Jan; 47(1):211-4. doi:
. [PMID: 12064656] - J S Kao, A Garg, M Mao-Qiang, D Crumrine, R Ghadially, K R Feingold, P M Elias. Testosterone perturbs epidermal permeability barrier homeostasis.
The Journal of investigative dermatology.
2001 Mar; 116(3):443-51. doi:
10.1046/j.1523-1747.2001.01281.x. [PMID: 11231319] - D R Goldstein, T Dobbs, B Krull, V J Plumb. Clenbuterol and anabolic steroids: a previously unreported cause of myocardial infarction with normal coronary arteriograms.
Southern medical journal.
1998 Aug; 91(8):780-4. doi:
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1998 Jan; 9(1):41-4. doi:
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The Journal of clinical endocrinology and metabolism.
1997 Nov; 82(11):3793-6. doi:
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Medicine and science in sports and exercise.
1997 May; 29(5):615-9. doi:
10.1097/00005768-199705000-00005. [PMID: 9140897] - E M Kouri, H G Pope, P S Oliva. Changes in lipoprotein-lipid levels in normal men following administration of increasing doses of testosterone cypionate.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.
1996 Jul; 6(3):152-7. doi:
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Magnesium research.
1996 Mar; 9(1):13-21. doi:
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Magnesium research.
1996 Mar; 9(1):23-31. doi:
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1995 Oct; 5(4):223-8. doi:
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Journal of pharmacological and toxicological methods.
1995 Aug; 33(4):187-95. doi:
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Circulation.
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Brain research.
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Magnesium research.
1994 Dec; 7(3-4):223-32. doi:
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The Journal of pediatrics.
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