N-acetylneuraminate (BioDeep_00000001628)
Secondary id: BioDeep_00000014329, BioDeep_00000260987
natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Volatile Flavor Compounds
代谢物信息卡片
(4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2, 3-trihydroxypropyl]oxane-2-carboxylic acid
化学式: C11H19NO9 (309.1059764)
中文名称: N-乙酰神经氨酸, 乙酰神经氨酸
谱图信息:
最多检出来源 Viridiplantae(plant) 75%
Reviewed
Last reviewed on 2024-09-13.
Cite this Page
N-acetylneuraminate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/n-acetylneuraminate (retrieved
2024-11-24) (BioDeep RN: BioDeep_00000001628). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O
InChI: InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)
描述信息
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID A018; [MS2] KO008824
KEIO_ID A018
N-Acetylneuraminic acid is a sialic acid monosaccharide ubiquitous on cell membrane glycoproteins and glycolipids of mammalian cell ganglioglycerides, which plays a biological role in neurotransmission, leukocyte vasodilation, and viral or bacterial infection.
同义名列表
13 个代谢物同义名
(4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2, 3-trihydroxypropyl]oxane-2-carboxylic acid; (4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid; 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid; Neuraminic acid, N-acetyl-; N-Acetyl-neuraminic acid; N-Acetylneuraminic acid; N-Acetylneuraminate; Neu5ac; N-Acetylneuraminic acid; NANA; Lactaminic acid; N-Acetylneuraminate; (-)-N-Acetylneuraminic acid
数据库引用编号
42 个数据库交叉引用编号
- ChEBI: CHEBI:17012
- KEGG: C00270
- PubChem: 439197
- PubChem: 3568
- PubChem: 906
- HMDB: HMDB0000230
- Metlin: METLIN24101
- ChEMBL: CHEMBL4280954
- ChEMBL: CHEMBL112030
- MeSH: N-Acetylneuraminic Acid
- CAS: 6918-20-3
- CAS: 131-48-6
- MoNA: PS047402
- MoNA: PS047410
- MoNA: PS047409
- MoNA: PS047411
- MoNA: KO000037
- MoNA: PS047401
- MoNA: KO008824
- MoNA: KO002072
- MoNA: KO002069
- MoNA: KO008826
- MoNA: KO000035
- MoNA: KO000038
- MoNA: KO002071
- MoNA: KO008825
- MoNA: KO000036
- MoNA: PR100695
- MoNA: PS047408
- MoNA: KO002068
- MoNA: KO000034
- MoNA: PS047407
- MoNA: KO002070
- PMhub: MS000000881
- KNApSAcK: C00019584
- PDB-CCD: SIA
- PDB-CCD: SLB
- 3DMET: B04658
- NIKKAJI: J10.009I
- RefMet: N-Acetylneuraminic acid
- medchemexpress: HY-I0400
- KNApSAcK: 17012
分类词条
相关代谢途径
Reactome(6)
BioCyc(0)
PlantCyc(0)
代谢反应
14 个相关的代谢反应过程信息。
Reactome(10)
- Metabolism of proteins:
EIF5A2 + NAD + SPM ⟶ 1,3-diaminopropane + H+ + H0ZKZ7 + NADH - Post-translational protein modification:
EIF5A2 + NAD + SPM ⟶ 1,3-diaminopropane + H+ + H0ZKZ7 + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
Fru(6)P + L-Gln ⟶ GlcN6P + L-Glu - Sialic acid metabolism:
ATP + ManNAc ⟶ ADP + ManNAc-6-P - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Sphingolipid metabolism:
H2O + dehydroepiandrosterone sulfate ⟶ DHEA + SO4(2-) - Glycosphingolipid metabolism:
H2O + dehydroepiandrosterone sulfate ⟶ DHEA + SO4(2-)
BioCyc(3)
- superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation:
N-acetyl-D-glucosamine-6-phosphate + H2O ⟶ D-glucosamine 6-phosphate + acetate - N-acetylneuraminate and N-acetylmannosamine degradation:
N-acetyl-D-mannosamine + ATP ⟶ N-acetyl-D-mannosamine-6-phosphate + ADP + H+ - N-acetylneuraminate biosynthesis II (bacteria):
N-acetyl-D-mannosamine + H2O + H+ + phosphoenolpyruvate ⟶ N-acetylneuraminate + phosphate
WikiPathways(0)
Plant Reactome(0)
INOH(1)
- Aminosugars metabolism ( Aminosugars metabolism ):
D-Fructose 6-phosphate + NH3 ⟶ D-Glucosamine 6-phosphate + H2O
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 3708 - Brassica napus: 10.3389/FNUT.2022.822033
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 5691 - Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wenliang Sun, Chao Han, Ruirui Ge, Xiaotong Jiang, Yu Wang, Yingchao Han, Ning Wang, Yanzhi Song, Mingshi Yang, Guoliang Chen, Yihui Deng. Sialic Acid Conjugate-Modified Cationic Liposomal Paclitaxel for Targeted Therapy of Lung Metastasis in Breast Cancer: What a Difference the Cation Content Makes.
Molecular pharmaceutics.
2024 Apr; 21(4):1625-1638. doi:
10.1021/acs.molpharmaceut.3c00767. [PMID: 38403951] - Michael J Currie, James S Davies, Mariafrancesca Scalise, Ashutosh Gulati, Joshua D Wright, Michael C Newton-Vesty, Gayan S Abeysekera, Ramaswamy Subramanian, Weixiao Y Wahlgren, Rosmarie Friemann, Jane R Allison, Peter D Mace, Michael D W Griffin, Borries Demeler, Soichi Wakatsuki, David Drew, Cesare Indiveri, Renwick C J Dobson, Rachel A North. Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
eLife.
2024 Feb; 12(?):. doi:
10.7554/elife.92307. [PMID: 38349818] - Tripti Halder, Bijit Saha, Namdev Dhas, Sanjeev Acharya, Niyati Acharya. Development and evaluation of multi-functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease.
Drug development research.
2024 Feb; 85(1):e22146. doi:
10.1002/ddr.22146. [PMID: 38349270] - Ricardo Zamudio Cañas, María Eugenia Jaramillo Flores, Verónica Vallejo Ruiz, Raúl Jacobo Delgado Macuil, Valentín López Gayou. Detection of Sialic Acid to Differentiate Cervical Cancer Cell Lines Using a Sambucus nigra Lectin Biosensor.
Biosensors.
2024 Jan; 14(1):. doi:
10.3390/bios14010034. [PMID: 38248411] - Ashok Kumar Jangid, Sungjun Kim, Hee Won Park, Hyun Jin Kim, Kyobum Kim. Ex Vivo Surface Decoration of Phenylboronic Acid onto Natural Killer Cells for Sialic Acid-Mediated Versatile Cancer Cell Targeting.
Biomacromolecules.
2024 Jan; 25(1):222-237. doi:
10.1021/acs.biomac.3c00916. [PMID: 38130077] - Shunfang Liu, Yaozhen He, Minding Feng, Yongtong Huang, Wenhao Wu, Jiu Wang. Targeted Delivery of Arctigenin Using Sialic Acid Conjugate-Modified Liposomes for the Treatment of Breast Cancer.
Molecules (Basel, Switzerland).
2024 Jan; 29(1):. doi:
10.3390/molecules29010278. [PMID: 38202860] - Xueying Tang, Jiashuo Zhang, Dezhi Sui, Qiongfen Yang, Tianyu Wang, Zihan Xu, Xiaoya Li, Xin Gao, Xinyang Yan, Xinrong Liu, Yanzhi Song, Yihui Deng. Simultaneous dendritic cells targeting and effective endosomal escape enhance sialic acid-modified mRNA vaccine efficacy and reduce side effects.
Journal of controlled release : official journal of the Controlled Release Society.
2023 12; 364(?):529-545. doi:
10.1016/j.jconrel.2023.11.008. [PMID: 37949317] - Reo Takeda, Ayaka Tabuchi, Yudai Nonaka, Ryotaro Kano, Mizuki Sudo, Yutaka Kano, Daisuke Hoshino. Cmah deficiency blunts cellular senescence in adipose tissues and improves whole-body glucose metabolism in aged mice.
Geriatrics & gerontology international.
2023 Nov; ?(?):. doi:
10.1111/ggi.14732. [PMID: 37968438] - Zhangyang Wang, Xiaoqun Nie, Fang Gao, Yanmin Tang, Yuanyuan Ma, Yiying Zhang, Yanqin Gao, Chen Yang, Jing Ding, Xin Wang. Increasing brain N-acetylneuraminic acid alleviates hydrocephalus-induced neurological deficits.
CNS neuroscience & therapeutics.
2023 11; 29(11):3183-3198. doi:
10.1111/cns.14253. [PMID: 37222223] - Yuna Guo, Pingping Wang, Liangyu Jiang, Chaowen Deng, Lei Zheng, Cong Song, Jianwei Jiao. Multifunctional Proximity Labeling Strategy for Lipid Raft-Specific Sialic Acid Tracking and Engineering.
Bioconjugate chemistry.
2023 Sep; ?(?):. doi:
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The journal of physical chemistry. B.
2023 08; 127(31):6940-6948. doi:
10.1021/acs.jpcb.3c02286. [PMID: 37523476] - Adam Wroński, Izabela Dobrzyńska, Szymon Sękowski, Wojciech Łuczaj, Ewa Olchowik-Grabarek, Elżbieta Skrzydlewska. Cannabidiol and Cannabigerol Modify the Composition and Physicochemical Properties of Keratinocyte Membranes Exposed to UVA.
International journal of molecular sciences.
2023 Aug; 24(15):. doi:
10.3390/ijms241512424. [PMID: 37569799] - Tomoko Kaburagi, Yuko Otsuka, Satoru Oshiro. Antiobesity Effect of N-Acetylneuraminic Acid by Enhancing Antioxidative Capacity in Mice Fed a High-Fat Diet.
Journal of medicinal food.
2023 Aug; 26(8):550-559. doi:
10.1089/jmf.2023.k.0016. [PMID: 37335945] - Yan Huang, Qiufang Zhang, Zhenzhen Guo, Guanhong Deng, Ruibin Chen, Yanfen Zheng. Potential noninvasive biomarkers for the malignant transformation of oral leukoplakia: A systematic review and meta-analysis.
Cancer medicine.
2023 May; ?(?):. doi:
10.1002/cam4.6095. [PMID: 37199052] - Geetanjali Negi, Anurag Sharma, Monika Chaudhary, Divya Gupta, Krishnan H Harshan, Nagma Parveen. SARS-CoV-2 Binding to Terminal Sialic Acid of Gangliosides Embedded in Lipid Membranes.
ACS infectious diseases.
2023 May; ?(?):. doi:
10.1021/acsinfecdis.3c00106. [PMID: 37145972] - Priyanka Bose, Manoj K Jaiswal, Sumit K Singh, Rakesh K Singh, Vinod K Tiwari. Growing impact of sialic acid-containing glycans in future drug discovery.
Carbohydrate research.
2023 May; 527(?):108804. doi:
10.1016/j.carres.2023.108804. [PMID: 37031650] - Xianmin Meng, Hongxia Zhang, Lingyan Chen, Mingqi Wang, Kaituo Zhang, Xinrong Liu, Yihui Deng, Yanzhi Song. Liposomal Doxorubicin: the Sphingomyelin/Cholesterol System Significantly Enhances the Antitumor Efficacy of Doxorubicin.
AAPS PharmSciTech.
2023 Feb; 24(2):64. doi:
10.1208/s12249-022-02489-1. [PMID: 36759405] - Petra Kranaster, Jonathan Blum, Jeremias E G A Dold, Valentin Wittmann, Marcel Leist. Use of metabolic glycoengineering and pharmacological inhibitors to assess lipid and protein sialylation on cells.
Journal of neurochemistry.
2023 Feb; 164(4):481-498. doi:
10.1111/jnc.15737. [PMID: 36504018] - Katerina V Djambazova, Martin Dufresne, Lukasz G Migas, Angela R S Kruse, Raf Van de Plas, Richard M Caprioli, Jeffrey M Spraggins. MALDI TIMS IMS of Disialoganglioside Isomers─GD1a and GD1b in Murine Brain Tissue.
Analytical chemistry.
2023 01; 95(2):1176-1183. doi:
10.1021/acs.analchem.2c03939. [PMID: 36574465] - Erhard Bieberich. Synthesis, Processing, and Function of N-Glycans in N-Glycoproteins.
Advances in neurobiology.
2023; 29(?):65-93. doi:
10.1007/978-3-031-12390-0_3. [PMID: 36255672] - Roger Sandhoff, Konrad Sandhoff. Neuronal Ganglioside and Glycosphingolipid (GSL) Metabolism and Disease : Cascades of Secondary Metabolic Errors Can Generate Complex Pathologies (in LSDs).
Advances in neurobiology.
2023; 29(?):333-390. doi:
10.1007/978-3-031-12390-0_12. [PMID: 36255681] - A V Poznyak, D A Kashirskikh, A Y Postnov, M A Popov, V N Sukhorukov, A N Orekhov. Sialic acid as the potential link between lipid metabolism and inflammation in the pathogenesis of atherosclerosis.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2023; 56(?):e12972. doi:
10.1590/1414-431x2023e12972. [PMID: 38088673] - Bertan Boran Bayrak, Gonul Yenidogan Kulak, Refiye Yanardag, Aysen Yarat. Short term deuterium depletion in drinking water reduced tumor induced oxidative stress in mice liver.
Pathology, research and practice.
2022 Dec; 240(?):154186. doi:
10.1016/j.prp.2022.154186. [PMID: 36327814] - Dileknur Topaloglu, Ismet Burcu Turkyilmaz, Refiye Yanardag. Gastroprotective effect of vitamin U in D-galactosamine-induced hepatotoxicity.
Journal of biochemical and molecular toxicology.
2022 Sep; 36(9):e23124. doi:
10.1002/jbt.23124. [PMID: 35670011] - Martin F Peter, Jan A Ruland, Peer Depping, Niels Schneberger, Emmanuele Severi, Jonas Moecking, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Jan Peter Siebrasse, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Ulrich Kubitscheck, Gavin H Thomas, Gregor Hagelueken. Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Nature communications.
2022 08; 13(1):4471. doi:
10.1038/s41467-022-31907-y. [PMID: 35927235] - Lauren Byrd-Leotis, Nan Jia, Yasuyuki Matsumoto, Dongli Lu, Yoshihiro Kawaoka, David A Steinhauer, Richard D Cummings. Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies.
Scientific reports.
2022 07; 12(1):12757. doi:
10.1038/s41598-022-16605-5. [PMID: 35882911] - Mengying Liu, Liane Z X Huang, Anthony A Smits, Christian Büll, Yoshiki Narimatsu, Frank J M van Kuppeveld, Henrik Clausen, Cornelis A M de Haan, Erik de Vries. Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions.
Nature communications.
2022 07; 13(1):4054. doi:
10.1038/s41467-022-31840-0. [PMID: 35831293] - Yaoming Chen, Yuting He, Xiaoxia Zhan, Dubo Chen, Pinning Feng, Yan Yan, Yichong Wang. Sialic Acid as a Suitable Marker of Clinical Disease Activity in Patients with Crohn's Disease.
Laboratory medicine.
2022 Jul; 53(4):381-385. doi:
10.1093/labmed/lmac006. [PMID: 35199160] - Lieh-Bang Liou, Ting-Yi Wang, I-Ju Liu, Han-Chung Wu, Po-Yuan Ke, Yao-Fan Fang, Yen-Fu Chen. α-2,6-sialic acid/IgG anti-dsDNA ratios correlate with human lupus disease activity and possible mechanisms: A pilot study.
Lupus.
2022 Jul; 31(8):927-938. doi:
10.1177/09612033221099766. [PMID: 35531921] - Hongbing Liu, Dongdong Liu, Muse Ji, Peifu Xiao, Yi Qin, Jiansong Zhao, Na Wang, Jingxin Gou, Tian Yin, Haibing He, Guoliang Chen, Yu Zhang, Xing Tang. Inflammation-targeted sialic acid-dexamethasone conjugates for reducing the side effects of glucocorticoids.
International journal of pharmaceutics.
2022 Jun; 622(?):121900. doi:
10.1016/j.ijpharm.2022.121900. [PMID: 35690305] - Kathia Antillon, Patrick A Ross, Mark P Farrell. Directing CAR NK Cells via the Metabolic Incorporation of CAR Ligands into Malignant Cell Glycans.
ACS chemical biology.
2022 06; 17(6):1505-1512. doi:
10.1021/acschembio.2c00173. [PMID: 35648806] - Junfang Wu, Mingming Zhao, Haoran Wei, Chenze Li, Dong Hu, Lemin Zheng, Dao Wen Wang. Neuraminidase inhibitor treatment is associated with decreased mortality in COVID-19 patients: a retrospective analysis.
European heart journal. Cardiovascular pharmacotherapy.
2022 06; 8(4):392-401. doi:
10.1093/ehjcvp/pvac018. [PMID: 35294004] - Dianne E van der Wal, Laura M Rey Gomez, Thomas Hueneburg, Claire Linnane, Denese C Marks. Changes in glycans on platelet microparticles released during storage of apheresis platelets are associated with phosphatidylserine externalization and phagocytosis.
Transfusion.
2022 06; 62(6):1289-1301. doi:
10.1111/trf.16891. [PMID: 35467785] - Yuanfei Ge, Jinyong Wu, Min Pang, Dan Hu, Zhongkui Li, Xiangqin Wang, Lijie Sun, Xiangsong Chen, Jianming Yao. Novel carboxymethyl chitosan/N-acetylneuraminic acid hydrogel for the protection of Pediococcus pentosaceus.
Food research international (Ottawa, Ont.).
2022 06; 156(?):111355. doi:
10.1016/j.foodres.2022.111355. [PMID: 35650981] - Mbateudi Danjuma Ika, Mohammed Auwal Ibrahim, Abdullahi Balarabe Sallau, Abdulmalik Abdullahi Salman, Abubakar Muhammad Sani, Murtala Bindawa Isah. Variations in the Serum Sialic Acid Profiles of Malaria Patients in Zaria, Nigeria: A Cross-Sectional Study.
Acta parasitologica.
2022 Jun; 67(2):1010-1014. doi:
10.1007/s11686-021-00503-3. [PMID: 35000113] - Davide Ret, Linda Stefenatti, Alessio Gentile, Johanna Rohrhofer, Simone Knaus, Eva Untersmayr. DMTMM-mediated methylamidation for MALDI mass spectrometry analysis of N-glycans with structurally conserved sialic acid residues in biological fluids "via direttissima".
Talanta.
2022 May; 242(?):123326. doi:
10.1016/j.talanta.2022.123326. [PMID: 35193013] - Simon J L Petitjean, Wenzhang Chen, Melanie Koehler, Ravikumar Jimmidi, Jinsung Yang, Danahe Mohammed, Blinera Juniku, Megan L Stanifer, Steeve Boulant, Stéphane P Vincent, David Alsteens. Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection.
Nature communications.
2022 05; 13(1):2564. doi:
10.1038/s41467-022-30313-8. [PMID: 35538121] - Alan B Moran, Richard A Gardner, Manfred Wuhrer, Guinevere S M Lageveen-Kammeijer, Daniel I R Spencer. Sialic Acid Derivatization of Fluorescently Labeled N-Glycans Allows Linkage Differentiation by Reversed-Phase Liquid Chromatography-Fluorescence Detection-Mass Spectrometry.
Analytical chemistry.
2022 05; 94(18):6639-6648. doi:
10.1021/acs.analchem.1c02610. [PMID: 35482581] - Naazneen Khan, Aniruddha Sasmal, Zahra Khedri, Patrick Secrest, Andrea Verhagen, Saurabh Srivastava, Nissi Varki, Xi Chen, Hai Yu, Travis Beddoe, Adrienne W Paton, James C Paton, Ajit Varki. Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits.
The Journal of biological chemistry.
2022 05; 298(5):101900. doi:
10.1016/j.jbc.2022.101900. [PMID: 35398357] - Weiqi Hong, Jingyun Yang, Jun Zou, Zhenfei Bi, Cai He, Hong Lei, Xuemei He, Xue Li, Aqu Alu, Wenyan Ren, Zeng Wang, Xiaohua Jiang, Kunhong Zhong, Guowen Jia, Yun Yang, Wenhai Yu, Qing Huang, Mengli Yang, Yanan Zhou, Yuan Zhao, Dexuan Kuang, Junbin Wang, Haixuan Wang, Siyuan Chen, Min Luo, Ziqi Zhang, Tianqi Lu, Li Chen, Haiying Que, Zhiyao He, Qiu Sun, Wei Wang, Guobo Shen, Guangwen Lu, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Jiong Li, Xiangrong Song, Lunzhi Dai, Chong Chen, Jia Geng, Maling Gou, Lu Chen, Haohao Dong, Yong Peng, Canhua Huang, Zhiyong Qian, Wei Cheng, Changfa Fan, Yuquan Wei, Zhaoming Su, Aiping Tong, Shuaiyao Lu, Xiaozhong Peng, Xiawei Wei. Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells.
Cellular & molecular immunology.
2022 May; 19(5):577-587. doi:
10.1038/s41423-022-00845-6. [PMID: 35273357] - Luca Unione, María J Moure, Maria Pia Lenza, Iker Oyenarte, June Ereño-Orbea, Ana Ardá, Jesús Jiménez-Barbero. The SARS-CoV-2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View.
Angewandte Chemie (International ed. in English).
2022 04; 61(18):e202201432. doi:
10.1002/anie.202201432. [PMID: 35191576] - Jordan D Zehr, Sergei L Kosakovsky Pond, Darren P Martin, Kristina Ceres, Gary R Whittaker, Jean K Millet, Laura B Goodman, Michael J Stanhope. Recent Zoonotic Spillover and Tropism Shift of a Canine Coronavirus Is Associated with Relaxed Selection and Putative Loss of Function in NTD Subdomain of Spike Protein.
Viruses.
2022 04; 14(5):. doi:
10.3390/v14050853. [PMID: 35632597] - Elisabeth Gludovacz, Marlene Resch, Kornelia Schuetzenberger, Karin Petroczi, Daniel Maresch, Stefan Hofbauer, Bernd Jilma, Nicole Borth, Thomas Boehm. Glycosylation site Asn168 is important for slow in vivo clearance of recombinant human diamine oxidase heparin-binding motif mutants.
Glycobiology.
2022 04; 32(5):404-413. doi:
10.1093/glycob/cwab122. [PMID: 35088086] - Jiwon Hwang, Ye Rim Kim, Jung Yeon Park, Woo Hyun Nam, Jehan Kim, Jinhan Cho, Yongju Kim. Selective Anticancer Materials by Self-Assembly of Synthetic Amphiphiles Based on N-Acetylneuraminic Acid.
ACS applied materials & interfaces.
2022 Apr; 14(14):16100-16107. doi:
10.1021/acsami.2c02922. [PMID: 35377593] - Jordi L Tremoleda, Beverley Law. Success for our first Virtual LASA Annual Conference.
Laboratory animals.
2022 04; 56(2):201-203. doi:
10.1177/00236772221081776. [PMID: 35511490] - Anne Trappe, Florian Füssl, Silvia Millán-Martín, Rachel Ronan, Izabella Zaborowska, Jonathan Bones. Correlative N-glycan and charge variant analysis of cetuximab expressed in murine, chinese hamster and human expression systems.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2022 Apr; 1194(?):123186. doi:
10.1016/j.jchromb.2022.123186. [PMID: 35240429] - Mengxia Cheng, Hong Shu, Maohua Yang, Guoquan Yan, Lei Zhang, Liang Wang, Wenning Wang, Haojie Lu. Fast Discrimination of Sialylated N-Glycan Linkage Isomers with One-Step Derivatization by Microfluidic Capillary Electrophoresis-Mass Spectrometry.
Analytical chemistry.
2022 03; 94(11):4666-4676. doi:
10.1021/acs.analchem.1c04760. [PMID: 35258917] - Pelin Uysal, Duygu Teksoz, Hulya Aksan, Sinem Durmus, Lebriz Uslu-Besli, Caglar Cuhadaroglu, Remise Gelisgen, Gonul Simsek, Hafize Uzun. Relationship between serum sialic acid levels and prolidase activity with airflow obstruction in patients with COPD.
Medicine.
2022 Mar; 101(11):. doi:
10.1097/md.0000000000028949. [PMID: 35356903] - Juan Li, Ting Wu, Xiucui Zhang, Yiping Du, Bo Wei, Junxue Wang. Clinical application of liver diseases diagnosis using ultrahigh-sensitive liquid chromatography-mass spectrometry for sialic acids detection.
Journal of chromatography. A.
2022 Mar; 1666(?):462837. doi:
10.1016/j.chroma.2022.462837. [PMID: 35123166] - Jack Cheeseman, Concepcion Badia, Rebecca I Thomson, Gunter Kuhnle, Richard A Gardner, Daniel I R Spencer, Helen M I Osborn. Quantitative Standards of 4-O-Acetyl- and 9-O-Acetyl-N-Acetylneuraminic Acid for the Analysis of Plasma and Serum.
Chembiochem : a European journal of chemical biology.
2022 03; 23(5):e202100662. doi:
10.1002/cbic.202100662. [PMID: 34874597] - Mark T Anderson, Stephanie D Himpsl, Lindsay A Mitchell, Leandra G Kingsley, Elizabeth P Snider, Harry L T Mobley. Identification of distinct capsule types associated with Serratia marcescens infection isolates.
PLoS pathogens.
2022 03; 18(3):e1010423. doi:
10.1371/journal.ppat.1010423. [PMID: 35353877] - Soracha E Ward, Jamie M O'Sullivan, Alan B Moran, Daniel I R Spencer, Richard A Gardner, Jyotika Sharma, Judicael Fazavana, Marco Monopoli, Thomas A J McKinnon, Alain Chion, Sandra Haberichter, James S O'Donnell. Sialylation on O-linked glycans protects von Willebrand factor from macrophage galactose lectin-mediated clearance.
Haematologica.
2022 03; 107(3):668-679. doi:
10.3324/haematol.2020.274720. [PMID: 33763999] - David E Scheim. A Deadly Embrace: Hemagglutination Mediated by SARS-CoV-2 Spike Protein at Its 22 N-Glycosylation Sites, Red Blood Cell Surface Sialoglycoproteins, and Antibody.
International journal of molecular sciences.
2022 Feb; 23(5):. doi:
10.3390/ijms23052558. [PMID: 35269703] - Mijung Oh, Dae-In Ha, Chaeyeon Son, Jeong Gu Kang, Heeyoun Hwang, Su Bin Moon, Minjeong Kim, Jihae Nam, Jung Soo Kim, Sang Yong Song, Yong-Sam Kim, Sangwoo Park, Jong Shin Yoo, Jeong-Heon Ko, Kyoungsook Park. Defect in cytosolic Neu2 sialidase abrogates lipid metabolism and impairs muscle function in vivo.
Scientific reports.
2022 02; 12(1):3216. doi:
10.1038/s41598-022-07033-6. [PMID: 35217678] - Huiling Dong, Yanan Gao, Xuefei Huang, Xuanjun Wu. Synthesis of sialic acid conjugates of the clinical near-infrared dye as next-generation theranostics for cancer phototherapy.
Journal of materials chemistry. B.
2022 02; 10(6):927-934. doi:
10.1039/d1tb02693c. [PMID: 35060591] - Berna Aslan Çetin, Pelin Ocal, Tulay Irez, Ezel Uslu, Kübra Irmak, Suat Karataş. The Association Between Follicular Fluid Sialic Acid Levels, Oocyte Quality, and Pregnancy Rates.
Reproductive sciences (Thousand Oaks, Calif.).
2022 02; 29(2):633-638. doi:
10.1007/s43032-021-00688-y. [PMID: 34264515] - Riham Abdel-Hamid Haroun, Waleed H Osman, Asmaa M Eessa. Evaluation of serum total sialic acid in moderate COVID-19 patients with and without gastrointestinal tract manifestations.
Tissue & cell.
2022 Feb; 74(?):101679. doi:
10.1016/j.tice.2021.101679. [PMID: 34801789] - Youxia Liu, Hongfen Li, Huyan Yu, Fanghao Wang, Junya Jia, Tiekun Yan. Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy.
BMC nephrology.
2022 01; 23(1):25. doi:
10.1186/s12882-021-02657-8. [PMID: 35016642] - Esther Llop, Rosa Peracaula. Lectin Affinity Chromatography for the Discovery of Novel Cancer Glycobiomarkers: A Case Study with PSA Glycoforms and Prostate Cancer.
Methods in molecular biology (Clifton, N.J.).
2022; 2370(?):301-313. doi:
10.1007/978-1-0716-1685-7_15. [PMID: 34611876] - Ravi Vattepu, Sunny Lyn Sneed, Robert M Anthony. Sialylation as an Important Regulator of Antibody Function.
Frontiers in immunology.
2022; 13(?):818736. doi:
10.3389/fimmu.2022.818736. [PMID: 35464485] - Attilio Cavezzi, Roberto Menicagli, Emidio Troiani, Salvatore Corrao. COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis.
F1000Research.
2022; 11(?):102. doi:
10.12688/f1000research.108667.2. [PMID: 35340277] - May E Montasser, Cristopher V Van Hout, Lawrence Miloscio, Alicia D Howard, Avraham Rosenberg, Myrasol Callaway, Biao Shen, Ning Li, Adam E Locke, Niek Verweij, Tanima De, Manuel A Ferreira, Luca A Lotta, Aris Baras, Thomas J Daly, Suzanne A Hartford, Wei Lin, Yuan Mao, Bin Ye, Derek White, Guochun Gong, James A Perry, Kathleen A Ryan, Qing Fang, Gannie Tzoneva, Evangelos Pefanis, Charleen Hunt, Yajun Tang, Lynn Lee, Carole Sztalryd-Woodle, Braxton D Mitchell, Matthew Healy, Elizabeth A Streeten, Simeon I Taylor, Jeffrey R O'Connell, Aris N Economides, Giusy Della Gatta, Alan R Shuldiner. Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen.
Science (New York, N.Y.).
2021 Dec; 374(6572):1221-1227. doi:
10.1126/science.abe0348. [PMID: 34855475] - Damla Yildiz, Suat Ekin, Sahin Sahinalp. Evaluations of Antioxidant Enzyme Activities, Total Sialic Acid and Trace Element Levels in Coronary Artery Bypass Grafting Patients.
Brazilian journal of cardiovascular surgery.
2021 12; 36(6):769-779. doi:
10.21470/1678-9741-2020-0162. [PMID: 34236781] - Junfeng Huang, Danqing Wang, Richard David Shipman, Zexin Zhu, Yuan Liu, Lingjun Li. Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC material.
Analytical and bioanalytical chemistry.
2021 Dec; 413(29):7295-7303. doi:
10.1007/s00216-021-03433-1. [PMID: 34155551] - V C Divya, Balasubramanian Saravanakarthikeyan. In silico exploration of enzymes involved in sialic acid biosynthesis and their possible role in SARS-CoV-2 infection.
Journal of oral biosciences.
2021 12; 63(4):416-419. doi:
10.1016/j.job.2021.08.004. [PMID: 34506921] - Marta Bally, Stephan Block, Fredrik Höök, Göran Larson, Nagma Parveen, Gustaf E Rydell. Physicochemical tools for studying virus interactions with targeted cell membranes in a molecular and spatiotemporally resolved context.
Analytical and bioanalytical chemistry.
2021 Dec; 413(29):7157-7178. doi:
10.1007/s00216-021-03510-5. [PMID: 34490501] - Hendrik Hessefort, Angelina Gross, Simone Seeleithner, Markus Hessefort, Tanja Kirsch, Lukas Perkams, Klaus Ole Bundgaard, Karen Gottwald, David Rau, Christopher Günther Franz Graf, Elisabeth Rozanski, Sascha Weidler, Carlo Unverzagt. Chemical and Enzymatic Synthesis of Sialylated Glycoforms of Human Erythropoietin.
Angewandte Chemie (International ed. in English).
2021 12; 60(49):25922-25932. doi:
10.1002/anie.202110013. [PMID: 34523784] - Rabia Javeed, Dilshad Hussain, Fahmida Jabeen, Muhammad Salman Sajid, Batool Fatima, Muhammad Naeem Ashiq, Muhammad Najam-Ul-Haq. Apo-H (beta-2-glycoprotein) intact N-glycan analysis by MALDI-TOF-MS using sialic acid derivatization.
Analytical and bioanalytical chemistry.
2021 Dec; 413(30):7441-7449. doi:
10.1007/s00216-021-03701-0. [PMID: 34686894] - Yan Liu, Bin Wang, Qi-Zhang Liang, Fang-Shu Shi, Chun-Miao Ji, Xiao-Lian Yang, Yong-Le Yang, Pan Qin, Ruiai Chen, Yao-Wei Huang. Roles of Two Major Domains of the Porcine Deltacoronavirus S1 Subunit in Receptor Binding and Neutralization.
Journal of virology.
2021 11; 95(24):e0111821. doi:
10.1128/jvi.01118-21. [PMID: 34549985] - Nobuhiko Okamoto, Tatsuyuki Ohto, Takashi Enokizono, Yoshinao Wada, Tomohiro Kohmoto, Issei Imoto, Yoshimi Haga, Junichi Seino, Tadashi Suzuki. Siblings with MAN1B1-CDG Showing Novel Biochemical Profiles.
Cells.
2021 11; 10(11):. doi:
10.3390/cells10113117. [PMID: 34831340] - Anoopjit Singh Kooner, Sandra Diaz, Hai Yu, Abhishek Santra, Ajit Varki, Xi Chen. Chemoenzymatic Synthesis of Sialosides Containing 7-N- or 7,9-Di-N-acetyl Sialic Acid as Stable O-Acetyl Analogues for Probing Sialic Acid-Binding Proteins.
The Journal of organic chemistry.
2021 11; 86(21):14381-14397. doi:
10.1021/acs.joc.1c01091. [PMID: 34636559] - Chenze Li, Mingming Zhao, Lei Xiao, Haoran Wei, Zheng Wen, Dong Hu, Bo Yu, Yang Sun, Jianing Gao, Xiaoqing Shen, Qi Zhang, Huanhuan Cao, Jin Huang, Wei Huang, Ke Li, Man Huang, Li Ni, Ting Yu, Liang Ji, Yangkai Xu, Gang Liu, Matthew C Konerman, Lemin Zheng, Dao Wen Wang. Prognostic Value of Elevated Levels of Plasma N-Acetylneuraminic Acid in Patients With Heart Failure.
Circulation. Heart failure.
2021 11; 14(11):e008459. doi:
10.1161/circheartfailure.121.008459. [PMID: 34711067] - Heinz Läubli, Kunio Kawanishi, Cijo George Vazhappilly, Rachel Matar, Maxime Merheb, Shoib Sarwar Siddiqui. Tools to study and target the Siglec-sialic acid axis in cancer.
The FEBS journal.
2021 11; 288(21):6206-6225. doi:
10.1111/febs.15647. [PMID: 33251699] - Guillermo Landa, Laura G Miranda-Calderon, Victor Sebastian, Silvia Irusta, Gracia Mendoza, Manuel Arruebo. Selective point-of-care detection of pathogenic bacteria using sialic acid functionalized gold nanoparticles.
Talanta.
2021 Nov; 234(?):122644. doi:
10.1016/j.talanta.2021.122644. [PMID: 34364453] - Nuria Carrillo, May C Malicdan, Petcharat Leoyklang, Joseph A Shrader, Galen Joe, Christina Slota, John Perreault, John D Heiss, Bradley Class, Chia-Ying Liu, Kennan Bradley, Colleen Jodarski, Carla Ciccone, Claire Driscoll, Rebecca Parks, Scott Van Wart, Levent Bayman, Christopher S Coffey, Melanie Quintana, Scott M Berry, Marjan Huizing, William A Gahl. Safety and efficacy of N-acetylmannosamine (ManNAc) in patients with GNE myopathy: an open-label phase 2 study.
Genetics in medicine : official journal of the American College of Medical Genetics.
2021 11; 23(11):2067-2075. doi:
10.1038/s41436-021-01259-x. [PMID: 34257421] - Zhengliang L Wu, James M Ertelt. Fluorescent glycan fingerprinting of SARS2 spike proteins.
Scientific reports.
2021 10; 11(1):20428. doi:
10.1038/s41598-021-98919-4. [PMID: 34650101] - Viktoria Dotz, Alessia Visconti, Hannah J Lomax-Browne, Florent Clerc, Agnes L Hipgrave Ederveen, Nicholas R Medjeral-Thomas, H Terence Cook, Matthew C Pickering, Manfred Wuhrer, Mario Falchi. O- and N-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function.
Journal of the American Society of Nephrology : JASN.
2021 10; 32(10):2455-2465. doi:
10.1681/asn.2020081208. [PMID: 34127537] - Wenjuan Du, Erik de Vries, Frank J M van Kuppeveld, Mikhail Matrosovich, Cornelis A M de Haan. Second sialic acid-binding site of influenza A virus neuraminidase: binding receptors for efficient release.
The FEBS journal.
2021 10; 288(19):5598-5612. doi:
10.1111/febs.15668. [PMID: 33314755] - Tomomi Ichimiya, Masatoshi Okamatsu, Takaaki Kinoshita, Daiki Kobayashi, Osamu Ichii, Naoki Yamamoto, Yoshihiro Sakoda, Hiroshi Kida, Hiroto Kawashima, Kazuo Yamamoto, Sayaka Takase-Yoden, Shoko Nishihara. Sulfated glycans containing NeuAcα2-3Gal facilitate the propagation of human H1N1 influenza A viruses in eggs.
Virology.
2021 10; 562(?):29-39. doi:
10.1016/j.virol.2021.06.008. [PMID: 34246113] - Lauren Byrd-Leotis, Yi Lasanajak, Thomas Bowen, Kelly Baker, Xuezheng Song, Mehul S Suthar, Richard D Cummings, David A Steinhauer. SARS-CoV-2 and other coronaviruses bind to phosphorylated glycans from the human lung.
Virology.
2021 10; 562(?):142-148. doi:
10.1016/j.virol.2021.07.012. [PMID: 34325286] - Shuo Wang, Xiaoxue Lai, Cong Li, Meng Chen, Miao Hu, Xinrong Liu, Yanzhi Song, Yihui Deng. Sialic acid-conjugate modified doxorubicin nanoplatform for treating neutrophil-related inflammation.
Journal of controlled release : official journal of the Controlled Release Society.
2021 09; 337(?):612-627. doi:
10.1016/j.jconrel.2021.07.044. [PMID: 34332025] - Haiyan Gao, Yueqi Qin, Jie Zeng, Qing Yang, Tian Jia. Dietary intervention with sialylated lactulose affects the immunomodulatory activities of mice.
Journal of dairy science.
2021 Sep; 104(9):9494-9504. doi:
10.3168/jds.2021-20327. [PMID: 34176623] - Sarah J Meyer, Marie Steffensen, Andreas Acs, Thomas Weisenburger, Charlotte Wadewitz, Thomas H Winkler, Lars Nitschke. CD22 Controls Germinal Center B Cell Receptor Signaling, Which Influences Plasma Cell and Memory B Cell Output.
Journal of immunology (Baltimore, Md. : 1950).
2021 08; 207(4):1018-1032. doi:
10.4049/jimmunol.2100132. [PMID: 34330755] - Hai Yu, Madhusudhan Reddy Gadi, Yuanyuan Bai, Libo Zhang, Lei Li, Jun Yin, Peng G Wang, Xi Chen. Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains.
The Journal of organic chemistry.
2021 07; 86(13):8672-8682. doi:
10.1021/acs.joc.1c00450. [PMID: 34152144] - J Ma, S Gong, Y He, W Gao, W Hao, X Lan. Effects of oral sialic acid on gut development, liver function and gut microbiota in mice.
Letters in applied microbiology.
2021 Jul; 73(1):20-25. doi:
10.1111/lam.13447. [PMID: 33386625] - Daniel Musikant, Romina Higa, Cristina E Rodríguez, Martin M Edreira, Oscar Campetella, Alicia Jawerbaum, María S Leguizamón. Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection.
Biochimie.
2021 Jul; 186(?):82-93. doi:
10.1016/j.biochi.2021.04.005. [PMID: 33891967] - Kayla Templeton, Meiby Ramos, Jacqueline Rose, Bryan Le, Qingwen Zhou, Amin Cressman, Stephanie Ferreyra, Carlito B Lebrilla, Fernando Antonio Fierro. Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival.
International journal of molecular sciences.
2021 Jun; 22(13):. doi:
10.3390/ijms22136868. [PMID: 34206740] - Sonia Di Gaetano, Domenica Capasso, Pietro Delre, Luciano Pirone, Michele Saviano, Emilia Pedone, Giuseppe Felice Mangiatordi. More Is Always Better Than One: The N-Terminal Domain of the Spike Protein as Another Emerging Target for Hampering the SARS-CoV-2 Attachment to Host Cells.
International journal of molecular sciences.
2021 Jun; 22(12):. doi:
10.3390/ijms22126462. [PMID: 34208755] - Marjan Huizing, Mary E Hackbarth, David R Adams, Melissa Wasserstein, Marc C Patterson, Steven U Walkley, William A Gahl. Free sialic acid storage disorder: Progress and promise.
Neuroscience letters.
2021 06; 755(?):135896. doi:
10.1016/j.neulet.2021.135896. [PMID: 33862140] - Andreas Reif, Kevin Lam, Sascha Weidler, Marie Lott, Irene Boos, Juliane Lokau, Christian Bretscher, Manuel Mönnich, Lukas Perkams, Marina Schmälzlein, Christopher Graf, Jan-Patrick Fischer, Carolin Lechner, Kerstin Hallstein, Stefan Becker, Michael Weyand, Clemens Steegborn, Gerhard Schultheiss, Stefan Rose-John, Christoph Garbers, Carlo Unverzagt. Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance.
Angewandte Chemie (International ed. in English).
2021 06; 60(24):13380-13387. doi:
10.1002/anie.202101496. [PMID: 33756033] - Tanya R McKitrick, Steffen M Bernard, Alexander J Noll, Bernard C Collins, Christoffer K Goth, Alyssa M McQuillan, Jamie Heimburg-Molinaro, Brantley R Herrin, Ian A Wilson, Max D Cooper, Richard D Cummings. Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins.
Communications biology.
2021 06; 4(1):674. doi:
10.1038/s42003-021-02199-7. [PMID: 34083726] - Scott Van Wart, Donald E Mager, Cindy J Bednasz, Marjan Huizing, Nuria Carrillo. Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy.
Drugs in R&D.
2021 Jun; 21(2):189-202. doi:
10.1007/s40268-021-00343-6. [PMID: 33893973] - Lufeng Bai, Qiuyu Xie, Min Xia, Kunjing Gong, Na Wang, Yuqing Chen, Minghui Zhao. The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H.
Journal of cellular and molecular medicine.
2021 05; 25(9):4316-4325. doi:
10.1111/jcmm.16492. [PMID: 33788378] - Yu-Jen Chang, Cheng-Yun Yeh, Ju-Chien Cheng, Yu-Qi Huang, Kai-Cheng Hsu, Yu-Feng Lin, Chih-Hao Lu. Potent sialic acid inhibitors that target influenza A virus hemagglutinin.
Scientific reports.
2021 04; 11(1):8637. doi:
10.1038/s41598-021-87845-0. [PMID: 33883588] - Ilona Dudka, Angelika Chachaj, Agata Sebastian, Wojciech Tański, Hans Stenlund, Gerhard Gröbner, Andrzej Szuba. Metabolomic profiling reveals plasma GlycA and GlycB as a potential biomarkers for treatment efficiency in rheumatoid arthritis.
Journal of pharmaceutical and biomedical analysis.
2021 Apr; 197(?):113971. doi:
10.1016/j.jpba.2021.113971. [PMID: 33639525] - Jinho Lee, Kyung Don Ju, Hyo Jin Kim, Bodokhsuren Tsogbadrakh, Hyunjin Ryu, Eunjeong Kang, Minjung Kang, Jaeseok Yang, Hee Gyung Kang, Curie Ahn, Kook-Hwan Oh. Soluble α-klotho anchors TRPV5 to the distal tubular cell membrane independent of FGFR1 by binding TRPV5 and galectin-1 simultaneously.
American journal of physiology. Renal physiology.
2021 04; 320(4):F559-F568. doi:
10.1152/ajprenal.00044.2021. [PMID: 33615893] - Liqi Liu, Zi Li, Jianfang Zhou, Jian Lu, Xiyan Li, Jia Liu, Ning Xiao, Dayan Wang. The effect of single amino acid substitution at position 220 in the hemagglutinin glycoprotein on avian influenza H7N9 candidate vaccine virus.
Virus genes.
2021 Apr; 57(2):164-171. doi:
10.1007/s11262-021-01827-y. [PMID: 33606171] - Freda E-C Jen, Margaret R Ketterer, Evgeny A Semchenko, Christopher J Day, Kate L Seib, Michael A Apicella, Michael P Jennings. The Lst Sialyltransferase of Neisseria gonorrhoeae Can Transfer Keto-Deoxyoctanoate as the Terminal Sugar of Lipooligosaccharide: a Glyco-Achilles Heel That Provides a New Strategy for Vaccines to Prevent Gonorrhea.
mBio.
2021 03; 12(2):. doi:
10.1128/mbio.03666-20. [PMID: 33758087] - Katarzyna Sołkiewicz, Hubert Krotkiewski, Marcin Jędryka, Ewa M Kratz. Variability of serum IgG sialylation and galactosylation degree in women with advanced endometriosis.
Scientific reports.
2021 03; 11(1):5586. doi:
10.1038/s41598-021-85200-x. [PMID: 33692455]