S-(1-Propenyl)-cysteine sulfoxide (BioDeep_00000000623)
Main id: BioDeep_00000019554
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
(2R)-2-Amino-3-[(1E)-prop-1-ene-1-sulphinyl]propanoic acid
化学式: C6H11NO3S (177.0459616)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=CS(=O)CC(C(=O)O)N
InChI: InChI=1S/C6H11NO3S/c1-2-3-11(10)4-5(7)6(8)9/h2-3,5H,4,7H2,1H3,(H,8,9)/b3-2+/t5-,11?/m0/s1
描述信息
S-(1-propenyl)-cysteine sulfoxide, also known as prensco, is a member of the class of compounds known as L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. S-(1-propenyl)-cysteine sulfoxide is soluble (in water) and a moderately acidic compound (based on its pKa). S-(1-propenyl)-cysteine sulfoxide can be found in a number of food items such as babassu palm, spirulina, elderberry, and cassava, which makes S-(1-propenyl)-cysteine sulfoxide a potential biomarker for the consumption of these food products.
D000970 - Antineoplastic Agents
D007004 - Hypoglycemic Agents
同义名列表
26 个代谢物同义名
(2R)-2-Amino-3-[(1E)-prop-1-ene-1-sulphinyl]propanoic acid; (2R)-2-Amino-3-((E)-prop-1-en-1-ylsulfinyl)propanoic acid; (2R)-2-amino-3-[(1E)-prop-1-ene-1-sulfinyl]propanoic acid; (2R)-2-Amino-3-((E)-prop-1-en-1-ylsulfinyl)propanoicacid; (2R)-2-amino-3-[(E)-prop-1-enyl]sulfinylpropanoic acid; (2R)-2-Amino-3-[(1E)-prop-1-ene-1-sulphinyl]propanoate; (2R)-2-Amino-3-[(1E)-prop-1-ene-1-sulfinyl]propanoate; L-Cysteine, S-(1E)-1-propen-1-yl-, S-oxide, [S(R)]-; S-[(E)-Prop-1-enyl]-L-cysteine S-oxide; S-(1-Propenyl)-cysteine sulphoxide; L-Alanine, 3-(1-propenylsulfinyl)-; S-(1-Propenyl)-cysteine sulfoxide; S-(2-propenyl)cysteine sulfoxide; 1-Propenyl-L-cysteine sulfoxide; s-propenyl-l-cysteine sulfoxide; 1-Propenylcysteine sulfoxide; alliin, (L-Ala)-(S)-isomer; alliin, (L-Ala)-(R)-isomer; S-allylcysteine sulfoxide; alliin, (L-Ala)-isomer; (R)-1-PeCSO; isoalliin; PRENCSO; 1-PeCSO; alliin; PCSO
数据库引用编号
16 个数据库交叉引用编号
- KEGG: C08295
- PubChem: 5281112
- HMDB: HMDB0302221
- Metlin: METLIN66892
- ChEMBL: CHEMBL464373
- MeSH: alliin
- KNApSAcK: C00001389
- foodb: FDB007929
- chemspider: 4444557
- CAS: 434322-95-9
- CAS: 16718-23-3
- CAS: 23315-20-0
- CAS: 3836-24-6
- medchemexpress: HY-111825A
- PubChem: 10493
- NIKKAJI: J570.765J
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wenhui Wu, Yang Xu, Yadi Zhang, Zhengjiao Yu, Yumeng Pang, Lei Qin, Yong Wang. [Cloning and functional analysis of AcFMO from onion during alliine biosynthesis].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology.
2024 Apr; 40(4):1076-1088. doi:
10.13345/j.cjb.230527. [PMID: 38658150] - Annalisa Chiavaroli, Fabrizio Masciulli, Cinzia Ingallina, Luisa Mannina, Maria Loreta Libero, Simonetta Cristina Di Simone, Alessandra Acquaviva, Nilofar, Lucia Recinella, Sheila Leone, Luigi Brunetti, Simone Carradori, Luca Cantò, Giustino Orlando, Gokhan Zengin, Abdullah Ibrahim Uba, Ugur Cakilcioğlu, Muzaffer Mukemre, Omer Elkiran, Maura Di Vito, Luigi Menghini, Claudio Ferrante. Comprehensive metabolite and biological profile of "Sulmona Red Garlic" ecotype's aerial bulbils.
Food research international (Ottawa, Ont.).
2024 Jan; 175(?):113654. doi:
10.1016/j.foodres.2023.113654. [PMID: 38129017] - Ricarda Freke, Björn Heinemann, Samuel Edward Hakim, Claus-Peter Witte, Marco Herde, Tatjana M Hildebrandt, Jakob Franke. Isotope-guided metabolomics reveals divergent incorporation of valine into different flavor precursor classes in chives.
Chembiochem : a European journal of chemical biology.
2023 Feb; ?(?):e202300056. doi:
10.1002/cbic.202300056. [PMID: 36853993] - Meitong Liu, Jing Lu, Shuting Yang, Yuelin Chen, Jing Yu, Shuang Guan. Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Feb; 160(?):112811. doi:
10.1016/j.fct.2022.112811. [PMID: 34999177] - Xuqin Yang, Yiren Su, Jiaying Wu, Wen Wan, Huijian Chen, Xiaoying Cao, Junjuan Wang, Zhong Zhang, Youzhi Wang, Deliang Ma, G J Loake, Jihong Jiang. Parallel analysis of global garlic gene expression and alliin content following leaf wounding.
BMC plant biology.
2021 Apr; 21(1):174. doi:
10.1186/s12870-021-02948-0. [PMID: 33838642] - Costanza Ceccanti, Gabriele Rocchetti, Luigi Lucini, Gianluca Giuberti, Marco Landi, Stefano Biagiotti, Lucia Guidi. Comparative phytochemical profile of the elephant garlic (Allium ampeloprasum var. holmense) and the common garlic (Allium sativum) from the Val di Chiana area (Tuscany, Italy) before and after in vitro gastrointestinal digestion.
Food chemistry.
2021 Feb; 338(?):128011. doi:
10.1016/j.foodchem.2020.128011. [PMID: 32950006] - Sucheta Khubber, Reza Hashemifesharaki, Mehrdad Mohammadi, Seyed Mohammad Taghi Gharibzahedi. Garlic (Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19.
Nutrition journal.
2020 11; 19(1):124. doi:
10.1186/s12937-020-00643-8. [PMID: 33208167] - Yuya Nakayama, Hsin-Jung Ho, Miki Yamagishi, Hiroyuki Ikemoto, Michio Komai, Hitoshi Shirakawa. Cysteine Sulfoxides Enhance Steroid Hormone Production via Activation of the Protein Kinase A Pathway in Testis-Derived I-10 Tumor Cells.
Molecules (Basel, Switzerland).
2020 Oct; 25(20):. doi:
10.3390/molecules25204694. [PMID: 33066465] - Murugan Sesha Subramanian, Giri Nandagopal Ms, Syafinaz Amin Nordin, Karuppiah Thilakavathy, Narcisse Joseph. Prevailing Knowledge on the Bioavailability and Biological Activities of Sulphur Compounds from Alliums: A Potential Drug Candidate.
Molecules (Basel, Switzerland).
2020 Sep; 25(18):. doi:
10.3390/molecules25184111. [PMID: 32916777] - Maria Giovanna Lupo, Noemi Biancorosso, Elisa Brilli, Germano Tarantino, Maria Pia Adorni, Greta Vivian, Marika Salvalaio, Stefano Dall'Acqua, Stefania Sut, Cédric Neutel, Haixia Chen, Alessandro Bressan, Elisabetta Faggin, Marcello Rattazzi, Nicola Ferri. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line.
Nutrients.
2020 Feb; 12(2):. doi:
10.3390/nu12020436. [PMID: 32050453] - Li-Jun Yue, Xi-Yu Zhu, Rui-Sha Li, Hui-Jing Chang, Bing Gong, Chong-Chong Tian, Chang Liu, Yun-Xing Xue, Qing Zhou, Tian-Shu Xu, Dong-Jin Wang. S‑allyl‑cysteine sulfoxide (alliin) alleviates myocardial infarction by modulating cardiomyocyte necroptosis and autophagy.
International journal of molecular medicine.
2019 Nov; 44(5):1943-1951. doi:
10.3892/ijmm.2019.4351. [PMID: 31573046] - Iveta Štefanová, Jakub Zápal, Martin Moos, Marek Kuzma, Roman Kubec. Isoalliin-Derived Thiolanes Formed in Homogenized Onion.
Journal of agricultural and food chemistry.
2019 Sep; 67(35):9895-9906. doi:
10.1021/acs.jafc.9b01384. [PMID: 31091093] - Juntong Yu, Hui Guo, Jinli Xie, Jianming Luo, Yuetong Li, Liu Liu, Shiyi Ou, Guangwen Zhang, Xichun Peng. The Alternate Consumption of Quercetin and Alliin in the Traditional Asian Diet Reshaped Microbiota and Altered Gene Expression of Colonic Epithelial Cells in Rats.
Journal of food science.
2019 Mar; 84(3):678-686. doi:
10.1111/1750-3841.14473. [PMID: 30768688] - Elham Zare, Amirhesam Alirezaei, Mahmood Bakhtiyari, Asieh Mansouri. Evaluating the effect of garlic extract on serum inflammatory markers of peritoneal dialysis patients: a randomized double-blind clinical trial study.
BMC nephrology.
2019 01; 20(1):26. doi:
10.1186/s12882-019-1204-6. [PMID: 30683061] - Nabarun Roy, P A Nazeem, T D Babu, P S Abida, Arunaksharan Narayanankutty, Ravisankar Valsalan, P A Valsala, Achuthan C Raghavamenon. EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide.
Interdisciplinary sciences, computational life sciences.
2018 Dec; 10(4):686-693. doi:
10.1007/s12539-017-0227-6. [PMID: 28349439] - Harumi Uto-Kondo, Ayumu Hase, Yusuke Yamaguchi, Ayaka Sakurai, Makoto Akao, Takeshi Saito, Hitomi Kumagai. S-Allyl-L-cysteine sulfoxide, a garlic odor precursor, suppresses elevation in blood ethanol concentration by accelerating ethanol metabolism and preventing ethanol absorption from gut.
Bioscience, biotechnology, and biochemistry.
2018 Apr; 82(4):724-731. doi:
10.1080/09168451.2018.1447357. [PMID: 29616890] - Baiqiang Zhai, Chuanhai Zhang, Yao Sheng, Changhui Zhao, Xiaoyun He, Wentao Xu, Kunlun Huang, Yunbo Luo. Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice.
Scientific reports.
2018 02; 8(1):3527. doi:
10.1038/s41598-018-21421-x. [PMID: 29476144] - Jing Lu, Bijun Cheng, Zhuoqun Meng, Baochen Fang, Tianjiao Li, Maocheng Sun, Meitong Liu, Shuang Guan. Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway.
Life sciences.
2018 Feb; 195(?):19-24. doi:
10.1016/j.lfs.2017.12.040. [PMID: 29305303] - Dandan Tao, Bing Zhou, Luyao Zhang, Xiaosong Hu, Xiaojun Liao, Yan Zhang. 'Laba' garlic processed by dense phase carbon dioxide: the relation between green colour generation and cellular structure, alliin consumption and alliinase activity.
Journal of the science of food and agriculture.
2016 Jul; 96(9):2969-75. doi:
10.1002/jsfa.7463. [PMID: 26374695] - Qing Chang, Yue'e Peng, Bin Shi, Conghui Dan, Yijun Yang, Qin Shuai. In situ Identification of Labile Precursor Compounds and their Short-lived Intermediates in Plants using in vivo Nanospray High-resolution Mass Spectrometry.
Phytochemical analysis : PCA.
2016 May; 27(3-4):184-90. doi:
10.1002/pca.2614. [PMID: 27313155] - Hirotaka Amano, Daichi Kazamori, Kenji Itoh. Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption.
The Journal of nutrition.
2016 Feb; 146(2):456S-459S. doi:
10.3945/jn.114.201749. [PMID: 26764325] - Ethiene Castellucci Estevam, Sharoon Griffin, Muhammad Jawad Nasim, Dariusz Zieliński, Justyna Aszyk, Magdalena Osowicka, Natalia Dawidowska, Rinaldi Idroes, Agnieszka Bartoszek, Claus Jacob. Inspired by Nature: The Use of Plant-derived Substrate/Enzyme Combinations to Generate Antimicrobial Activity in situ.
Natural product communications.
2015 Oct; 10(10):1733-8. doi:
. [PMID: 26669114] - Naoko Yoshimoto, Misato Onuma, Shinya Mizuno, Yuka Sugino, Ryo Nakabayashi, Shinsuke Imai, Tadamitsu Tsuneyoshi, Shin-ichiro Sumi, Kazuki Saito. Identification of a flavin-containing S-oxygenating monooxygenase involved in alliin biosynthesis in garlic.
The Plant journal : for cell and molecular biology.
2015 Sep; 83(6):941-51. doi:
10.1111/tpj.12954. [PMID: 26345717] - Wen-Qing Li, Hua Zhou, Mei-Yun Zhou, Xing-Peng Hu, Shi-Yi Ou, Ri-An Yan, Xiao-Jian Liao, Xue-Song Huang, Liang Fu. Characterization of phenolic constituents inhibiting the formation of sulfur-containing volatiles produced during garlic processing.
Journal of agricultural and food chemistry.
2015 Jan; 63(3):787-94. doi:
10.1021/jf505982f. [PMID: 25579175] - Su-Chen Ho, Min-Sheng Su. Evaluating the anti-neuroinflammatory capacity of raw and steamed garlic as well as five organosulfur compounds.
Molecules (Basel, Switzerland).
2014 Oct; 19(11):17697-714. doi:
10.3390/molecules191117697. [PMID: 25365295] - Nathalie Bernaert, Marc De Loose, Erik Van Bockstaele, Bart Van Droogenbroeck. Antioxidant changes during domestic food processing of the white shaft and green leaves of leek (Allium ampeloprasum var. porrum).
Journal of the science of food and agriculture.
2014 Apr; 94(6):1168-74. doi:
10.1002/jsfa.6389. [PMID: 24105673] - Michał Majewski. Allium sativum: facts and myths regarding human health.
Roczniki Panstwowego Zakladu Higieny.
2014; 65(1):1-8. doi:
. [PMID: 24964572] - Weng Ieong Tou, Su-Sen Chang, Dongchuan Wu, Ted Weita Lai, Yu Tian Wang, Chung Y Hsu, Calvin Yu-Chian Chen. Molecular level activation insights from a NR2A/NR2B agonist.
Journal of biomolecular structure & dynamics.
2014; 32(5):683-93. doi:
10.1080/07391102.2013.787371. [PMID: 23600691] - James D Kean, David Camfield, Jerome Sarris, Marni Kras, Richard Silberstein, Andrew Scholey, Con Stough. A randomized controlled trial investigating the effects of PCSO-524, a patented oil extract of the New Zealand green lipped mussel (Perna canaliculus), on the behaviour, mood, cognition and neurophysiology of children and adolescents (aged 6-14 years) experiencing clinical and sub-clinical levels of hyperactivity and inattention: study protocol ACTRN12610000978066.
Nutrition journal.
2013 Jul; 12(?):100. doi:
10.1186/1475-2891-12-100. [PMID: 23866813] - Nathalie Bernaert, Dorrit Wouters, Luc De Vuyst, Domien De Paepe, Hervé De Clercq, Erik Van Bockstaele, Marc De Loose, Bart Van Droogenbroeck. Antioxidant changes of leek (Allium ampeloprasum var. porrum) during spontaneous fermentation of the white shaft and green leaves.
Journal of the science of food and agriculture.
2013 Jul; 93(9):2146-53. doi:
10.1002/jsfa.6020. [PMID: 23408379] - Teresa Lavecchia, Giuseppina Rea, Amina Antonacci, Maria T Giardi. Healthy and adverse effects of plant-derived functional metabolites: the need of revealing their content and bioactivity in a complex food matrix.
Critical reviews in food science and nutrition.
2013; 53(2):198-213. doi:
10.1080/10408398.2010.520829. [PMID: 23072533] - Laurian Vlase, Marcel Parvu, Elena Alina Parvu, Anca Toiu. Chemical constituents of three Allium species from Romania.
Molecules (Basel, Switzerland).
2012 Dec; 18(1):114-27. doi:
10.3390/molecules18010114. [PMID: 23344191] - Nathalie Bernaert, Lien Goetghebeur, Hervé De Clercq, Marc De Loose, Els Daeseleire, Els Van Pamel, Erik Van Bockstaele, Bart Van Droogenbroeck. Influence of cultivar and harvest time on the amounts of isoalliin and methiin in leek (Allium ampeloprasum var. porrum).
Journal of agricultural and food chemistry.
2012 Nov; 60(44):10910-9. doi:
10.1021/jf302132a. [PMID: 23020262] - Xavier Lieben Louis, Ryan Murphy, Sijo Joseph Thandapilly, Liping Yu, Thomas Netticadan. Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide.
BMC complementary and alternative medicine.
2012 Aug; 12(?):140. doi:
10.1186/1472-6882-12-140. [PMID: 22931510] - Radu Vasile Bagiu, Brigitha Vlaicu, Monica Butnariu. Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae).
International journal of molecular sciences.
2012; 13(2):1426-1436. doi:
10.3390/ijms13021426. [PMID: 22408399] - Christian Starkenmann, Yvan Niclass, Myriam Troccaz. Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar).
Journal of agricultural and food chemistry.
2011 Sep; 59(17):9457-65. doi:
10.1021/jf202082f. [PMID: 21854077] - Jing Wang, Yanping Cao, Chengtao Wang, Baoguo Sun. Low-frequency and low-intensity ultrasound accelerates alliinase-catalysed synthesis of allicin in freshly crushed garlic.
Journal of the science of food and agriculture.
2011 Aug; 91(10):1766-72. doi:
10.1002/jsfa.4377. [PMID: 21480265] - Sekh Abdul Nasim, Bhupinder Dhir, Rashmi Kapoor, Samar Fatima, Mahmooduzzafar, Abdul Mujib. Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats.
Pharmaceutical biology.
2011 Apr; 49(4):416-21. doi:
10.3109/13880209.2010.521163. [PMID: 21391887] - Elke Bloem, Silvia Haneklaus, Ewald Schnug. Influence of fertilizer practices on S-containing metabolites in garlic (Allium sativum L.) under field conditions.
Journal of agricultural and food chemistry.
2010 Oct; 58(19):10690-6. doi:
10.1021/jf102009j. [PMID: 20828155] - Raquel Ruiz, M P García, A Lara, L A Rubio. Garlic derivatives (PTS and PTS-O) differently affect the ecology of swine faecal microbiota in vitro.
Veterinary microbiology.
2010 Jul; 144(1-2):110-7. doi:
10.1016/j.vetmic.2009.12.025. [PMID: 20080364] - Eleftherios Touloupakis, Demetrios F Ghanotakis. Nutraceutical use of garlic sulfur-containing compounds.
Advances in experimental medicine and biology.
2010; 698(?):110-21. doi:
10.1007/978-1-4419-7347-4_9. [PMID: 21520707] - S A Nasim, A Mujib, K Rashmi, F Samar, A Junaid, Mahmooduzzafar. Improved alliin yield in somatic embryos of Allium sativum L. (cv. Yamuna safed) as analyzed by HPTLC.
Acta biologica Hungarica.
2009 Dec; 60(4):441-54. doi:
10.1556/abiol.60.2009.4.10. [PMID: 20015835] - Roman Kubec, Eva Dadáková. Chromatographic methods for determination of S-substituted cysteine derivatives--a comparative study.
Journal of chromatography. A.
2009 Oct; 1216(41):6957-63. doi:
10.1016/j.chroma.2009.08.032. [PMID: 19733357] - Sejeong Kook, Gun-Hee Kim, Kiheon Choi. The antidiabetic effect of onion and garlic in experimental diabetic rats: meta-analysis.
Journal of medicinal food.
2009 Jun; 12(3):552-60. doi:
10.1089/jmf.2008.1071. [PMID: 19627203] - S A Nasim, B Dhir, F Samar, K Rashmi, Mahmooduzzafa, A Mujib. Sulphur treatment alters the therapeutic potency of alliin obtained from garlic leaf extract.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Apr; 47(4):888-92. doi:
10.1016/j.fct.2009.01.024. [PMID: 19271323] - T Sangeetha, S Darlin Quine. Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats.
Journal of applied toxicology : JAT.
2008 Jul; 28(5):710-6. doi:
10.1002/jat.1330. [PMID: 18172887] - Miguel Aguilar, Francisco Rincón. Improving knowledge of garlic paste greening through the design of an experimental strategy.
Journal of agricultural and food chemistry.
2007 Dec; 55(25):10266-74. doi:
10.1021/jf072075t. [PMID: 18001035] - I Chung, S H Kwon, S-T Shim, K H Kyung. Synergistic antiyeast activity of garlic oil and allyl alcohol derived from alliin in garlic.
Journal of food science.
2007 Nov; 72(9):M437-40. doi:
10.1111/j.1750-3841.2007.00545.x. [PMID: 18034739] - Hui Wang, Jingming Li, Zhengfu Wang, Xue Zhang, Yuanying Ni. Modified method for rapid quantitation of S-alk(en)yl-L-cysteine sulfoxide in yellow onions (Allium cepa L.).
Journal of agricultural and food chemistry.
2007 Jul; 55(14):5429-35. doi:
10.1021/jf070298d. [PMID: 17579424] - T Sangeetha, S Darlin Quine. Preventive effect of S-allyl cysteine sulfoxide (alliin) on lysosomal hydrolases and membrane-bound ATPases in isoproterenol-induced myocardial infarction in Wistar rats.
Journal of biochemical and molecular toxicology.
2007; 21(3):118-24. doi:
10.1002/jbt.20166. [PMID: 17623887] - Makoto Ichikawa, Nagatoshi Ide, Kazuhisa Ono. Changes in organosulfur compounds in garlic cloves during storage.
Journal of agricultural and food chemistry.
2006 Jun; 54(13):4849-54. doi:
10.1021/jf060083o. [PMID: 16787038] - Jill Hughes, Hamish A Collin, Angela Tregova, A Brian Tomsett, Richard Cosstick, Meriel G Jones. Effect of low storage temperature on some of the flavour precursors in garlic (Allium sativum).
Plant foods for human nutrition (Dordrecht, Netherlands).
2006 Jun; 61(2):81-5. doi:
10.1007/s11130-006-0018-4. [PMID: 16804741] - T Sangeetha, S Darlin Quine. Antilipoperoxidative and antioxidant effects of S-allyl cysteine sulfoxide on isoproterenol-induced myocardial infarction in Wistar rats.
Journal of biochemical and molecular toxicology.
2006; 20(4):167-73. doi:
10.1002/jbt.20132. [PMID: 16906521] - Lip Yong Chung. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide.
Journal of medicinal food.
2006; 9(2):205-13. doi:
10.1089/jmf.2006.9.205. [PMID: 16822206] - Fiona H Fry, Neal Okarter, Camilla Baynton-Smith, Michael J Kershaw, Nicholas J Talbot, Claus Jacob. Use of a substrate/alliinase combination to generate antifungal activity in situ.
Journal of agricultural and food chemistry.
2005 Feb; 53(3):574-80. doi:
10.1021/jf048481j. [PMID: 15686404] - Meriel G Jones, Jill Hughes, Angela Tregova, Jonothan Milne, A Brian Tomsett, Hamish A Collin. Biosynthesis of the flavour precursors of onion and garlic.
Journal of experimental botany.
2004 Aug; 55(404):1903-18. doi:
10.1093/jxb/erh138. [PMID: 15234988] - N Yamada, A Hattori, T Hayashi, T Nishikawa, H Fukuda, T Fujino. Improvement of scopolamine-induced memory impairment by Z-ajoene in the water maze in mice.
Pharmacology, biochemistry, and behavior.
2004 Aug; 78(4):787-91. doi:
10.1016/j.pbb.2004.05.017. [PMID: 15301936] - J Auger, W Yang, I Arnault, F Pannier, M Potin-Gautier. High-performance liquid chromatographic-inductively coupled plasma mass spectrometric evidence for Se-"alliins" in garlic and onion grown in Se-rich soil.
Journal of chromatography. A.
2004 Apr; 1032(1-2):103-7. doi:
10.1016/j.chroma.2003.11.077. [PMID: 15065784] - Michael Keusgen, Martina Jünger, Ingo Krest, Michael J Schöning. Development of a biosensor specific for cysteine sulfoxides.
Biosensors & bioelectronics.
2003 May; 18(5-6):805-12. doi:
10.1016/s0956-5663(03)00045-9. [PMID: 12706595] - A Helen, K Krishnakumar, P L Vijayammal, K T Augusti. A comparative study of antioxidants S-allyl cysteine sulfoxide and vitamin E on the damages induced by nicotine in rats.
Pharmacology.
2003 Mar; 67(3):113-7. doi:
10.1159/000067796. [PMID: 12571405] - Michael Keusgen, Hartwig Schulz, Janina Glodek, Ingo Krest, Hans Krüger, Nadine Herchert, Joachim Keller. Characterization of some Allium hybrids by aroma precursors, aroma profiles, and alliinase activity.
Journal of agricultural and food chemistry.
2002 May; 50(10):2884-90. doi:
10.1021/jf011331d. [PMID: 11982415] - N Gupta, T D Porter. Garlic and garlic-derived compounds inhibit human squalene monooxygenase.
The Journal of nutrition.
2001 Jun; 131(6):1662-7. doi:
10.1093/jn/131.6.1662. [PMID: 11385050] - Y Itakura, M Ichikawa, Y Mori, R Okino, M Udayama, T Morita. How to distinguish garlic from the other Allium vegetables.
The Journal of nutrition.
2001 03; 131(3s):963S-7S. doi:
10.1093/jn/131.3.963s. [PMID: 11238797] - P Milka, I Krest, M Keusgen. Immobilization of alliinase on porous aluminum oxide.
Biotechnology and bioengineering.
2000 Aug; 69(3):344-8. doi:
10.1002/1097-0290(20000805)69:3<344::aid-bit13>3.0.co;2-d. [PMID: 10861415] - R Kubec, M Svobodová, J Velísek. Gas chromatographic determination of S-alk(en)ylcysteine sulfoxides.
Journal of chromatography. A.
1999 Nov; 862(1):85-94. doi:
10.1016/s0021-9673(99)00902-4. [PMID: 10588342] - I Das, J Hirani, S Sooranna. Arginine is not responsible for the activation of nitric oxide synthase by garlic.
Journal of ethnopharmacology.
1996 Jul; 53(1):5-9. doi:
10.1016/0378-8741(96)01416-x. [PMID: 8807470] - K T Augusti, C G Sheela. Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats.
Experientia.
1996 Feb; 52(2):115-20. doi:
10.1007/bf01923354. [PMID: 8608811] - C G Sheela, K T Augusti. Effects of S-allyl cysteine sulfoxide isolated from Allium sativum Linn and gugulipid on some enzymes and fecal excretions of bile acids and sterols in cholesterol fed rats.
Indian journal of experimental biology.
1995 Oct; 33(10):749-51. doi:
NULL. [PMID: 8575806] - C G Sheela, K T Augusti. Antiperoxide effects of S-allyl cysteine sulphoxide isolated from Allium sativum Linn and gugulipid in cholesterol diet fed rats.
Indian journal of experimental biology.
1995 May; 33(5):337-41. doi:
". [PMID: 7558192] - A Rabinkov, X Z Zhu, G Grafi, G Galili, D Mirelman. Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning.
Applied biochemistry and biotechnology.
1994 Sep; 48(3):149-71. doi:
10.1007/bf02788739. [PMID: 7979352] - G Lachmann, D Lorenz, W Radeck, M Steiper. [The pharmacokinetics of the S35 labeled labeled garlic constituents alliin, allicin and vinyldithiine].
Arzneimittel-Forschung.
1994 Jun; 44(6):734-43. doi:
NULL. [PMID: 8053972] - C G Sheela, K T Augusti. Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn.
Indian journal of experimental biology.
1992 Jun; 30(6):523-6. doi:
. [PMID: 1506036] - P N Kourounakis, E A Rekka. Effect on active oxygen species of alliin and Allium sativum (garlic) powder.
Research communications in chemical pathology and pharmacology.
1991 Nov; 74(2):249-52. doi:
". [PMID: 1667340] - S Knasmüller, R de Martin, G Domjan, A Szakmary. Studies on the antimutagenic activities of garlic extract.
Environmental and molecular mutagenesis.
1989; 13(4):357-65. doi:
10.1002/em.2850130413. [PMID: 2661224] - G R Fenwick, A B Hanley. Allium species poisoning.
The Veterinary record.
1985 Jan; 116(1):28. doi:
10.1136/vr.116.1.28. [PMID: 3984170]