3,3',4,4',5-Pentachlorobiphenyl (BioDeep_00000009986)
Secondary id: BioDeep_00001873951
human metabolite blood metabolite Industrial Pollutants
代谢物信息卡片
3,4,5,3,4-Penta coplanar polychlorinated biphenyl
化学式: C12H5Cl5 (323.8834)
中文名称: 3,3,4,4,5-五氯联苯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1C2=CC(=C(C(=C2)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C12H5Cl5/c13-8-2-1-6(3-9(8)14)7-4-10(15)12(17)11(16)5-7/h1-5H
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:34317
- KEGG: C14573
- PubChem: 63090
- HMDB: HMDB0246010
- Metlin: METLIN70168
- ChEMBL: CHEMBL342696
- chemspider: 56775
- CAS: 57465-28-8
- PMhub: MS000023815
- PubChem: 17395573
- NIKKAJI: J164.843H
- KNApSAcK: 34317
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Manisha Agarwal, Katherine Roth, Zhao Yang, Rahul Sharma, Krishnarao Maddipati, Judy Westrick, Michael C Petriello. Loss of flavin-containing monooxygenase 3 modulates dioxin-like polychlorinated biphenyl 126-induced oxidative stress and hepatotoxicity.
Environmental research.
2024 Jun; 250(?):118492. doi:
10.1016/j.envres.2024.118492. [PMID: 38373550] - K Ronnie Rex, Paromita Chakraborty. Polychlorinated biphenyls in bovine milk from a typical informal electronic waste recycling and related source regions in southern India before and after the COVID-19 pandemic outbreak.
The Science of the total environment.
2024 Feb; 912(?):168879. doi:
10.1016/j.scitotenv.2023.168879. [PMID: 38013105] - Yu Xia, Dongliu Luo, Anqi Xu, Bing Zhao, Hongjin Lin, Haidong Yao, Shu Li. Insight into the mechanism of melatonin in attenuating PCB126-induced liver injury: Resistance to ROS-dependent NETs formation to alleviate inflammation and lipid metabolism dysfunction.
Ecotoxicology and environmental safety.
2024 Jan; 270(?):115923. doi:
10.1016/j.ecoenv.2023.115923. [PMID: 38171107] - Zeinab El Amine, Jean-François Mauger, Pascal Imbeault. Human Preadipocytes Differentiated under Hypoxia following PCB126 Exposure during Proliferation: Effects on Differentiation, Glucose Uptake and Adipokine Profile.
Cells.
2023 09; 12(18):. doi:
10.3390/cells12182326. [PMID: 37759548] - Belinda J Petri, Kellianne M Piell, Banrida Wahlang, Kimberly Z Head, Kalina Andreeva, Eric C Rouchka, Matthew C Cave, Carolyn M Klinge. Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease.
Environmental research.
2023 01; 216(Pt 3):114686. doi:
10.1016/j.envres.2022.114686. [PMID: 36341798] - Tyler C Gripshover, Banrida Wahlang, Kimberly Z Head, Jamie L Young, Jianzhu Luo, Muhammad T Mustafa, Irina A Kirpich, Matthew C Cave. The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol-associated liver disease.
Alcohol, clinical & experimental research.
2023 01; 47(1):60-75. doi:
10.1111/acer.14976. [PMID: 36377258] - Nazmin Akter Eti, Susanne Flor, Khursheed Iqbal, Regan L Scott, Violet E Klenov, Katherine N Gibson-Corley, Michael J Soares, Gabriele Ludewig, Larry W Robertson. PCB126 induced toxic actions on liver energy metabolism is mediated by AhR in rats.
Toxicology.
2022 01; 466(?):153054. doi:
10.1016/j.tox.2021.153054. [PMID: 34848246] - Shaniece Wauchope, Monika A Roy, William Irvine, Isaac Morrison, Eileen Brantley, Maxine Gossell-Williams, Alicia R Timme-Laragy, Rupika Delgoda. Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor.
Toxicology and applied pharmacology.
2021 05; 419(?):115502. doi:
10.1016/j.taap.2021.115502. [PMID: 33774063] - Pan Deng, Chunyan Wang, Banrida Wahlang, Travis Sexton, Andrew J Morris, Bernhard Hennig. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice.
Toxicology and applied pharmacology.
2020 12; 409(?):115301. doi:
10.1016/j.taap.2020.115301. [PMID: 33096110] - Monika A Roy, Perseverance R Duche, Alicia R Timme-Laragy. The sulfate metabolite of 3,3'-dichlorobiphenyl (PCB-11) impairs Cyp1a activity and increases hepatic neutral lipids in zebrafish larvae (Danio rerio).
Chemosphere.
2020 Dec; 260(?):127609. doi:
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Gut microbes.
2020 11; 12(1):1-16. doi:
10.1080/19490976.2020.1848209. [PMID: 33295235] - Jessie B Hoffman, Michael C Petriello, Andrew J Morris, M Abdul Mottaleb, Yipeng Sui, Changcheng Zhou, Pan Deng, Chunyan Wang, Bernhard Hennig. Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice.
Environmental pollution (Barking, Essex : 1987).
2020 Jun; 261(?):114183. doi:
10.1016/j.envpol.2020.114183. [PMID: 32105967] - Ashlee E Williams, James Watt, Larry W Robertson, Gopi Gadupudi, Michele L Osborn, Michael J Soares, Khursheed Iqbal, Kim B Pedersen, Kartik Shankar, Shana Littleton, Cole Maimone, Nazmin A Eti, Larry J Suva, Martin J J Ronis. Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat Is Aryl Hydrocarbon Receptor Dependent.
Toxicological sciences : an official journal of the Society of Toxicology.
2020 05; 175(1):113-125. doi:
10.1093/toxsci/kfaa030. [PMID: 32119087] - Martin J Ronis, James Watt, Casey F Pulliam, Ashlee E Williams, Alexander W Alund, Ezazul Haque, Gopi S Gadupudi, Larry W Robertson. Skeletal toxicity resulting from exposure of growing male rats to coplanar PCB 126 is associated with disruption of calcium homeostasis and the GH-IGF-1 axis and direct effects on bone formation.
Archives of toxicology.
2020 02; 94(2):389-399. doi:
10.1007/s00204-019-02645-w. [PMID: 31820026] - Monika A Roy, Karilyn E Sant, Olivia L Venezia, Alix B Shipman, Stephen D McCormick, Panithi Saktrakulkla, Keri C Hornbuckle, Alicia R Timme-Laragy. The emerging contaminant 3,3'-dichlorobiphenyl (PCB-11) impedes Ahr activation and Cyp1a activity to modify embryotoxicity of Ahr ligands in the zebrafish embryo model (Danio rerio).
Environmental pollution (Barking, Essex : 1987).
2019 Nov; 254(Pt A):113027. doi:
10.1016/j.envpol.2019.113027. [PMID: 31421573] - Xinming Shen, Yongjiu Chen, Jie Zhang, Xu Yan, Wei Liu, Yifan Guo, Qiuli Shan, Sijin Liu. Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Environment international.
2019 07; 128(?):146-157. doi:
10.1016/j.envint.2019.04.058. [PMID: 31055201] - Banrida Wahlang, Jian Jin, Josiah E Hardesty, Kimberly Z Head, Hongxue Shi, K Cameron Falkner, Russell A Prough, Carolyn M Klinge, Matthew C Cave. Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2019 Jul; 129(?):64-76. doi:
10.1016/j.fct.2019.04.007. [PMID: 31026535] - Yulang Chi, Yi Lin, Yanyang Lu, Qiansheng Huang, Guozhu Ye, Sijun Dong. Gut microbiota dysbiosis correlates with a low-dose PCB126-induced dyslipidemia and non-alcoholic fatty liver disease.
The Science of the total environment.
2019 Feb; 653(?):274-282. doi:
10.1016/j.scitotenv.2018.10.387. [PMID: 30412872] - Jessie B Hoffman, Michael D Flythe, Bernhard Hennig. Environmental pollutant-mediated disruption of gut microbial metabolism of the prebiotic inulin.
Anaerobe.
2019 Feb; 55(?):96-102. doi:
10.1016/j.anaerobe.2018.11.008. [PMID: 30447394] - Pan Deng, Jazmyne Barney, Michael C Petriello, Andrew J Morris, Banrida Wahlang, Bernhard Hennig. Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction.
Chemosphere.
2019 Feb; 217(?):140-149. doi:
10.1016/j.chemosphere.2018.10.196. [PMID: 30415113] - Hongxue Shi, Jian Jan, Josiah E Hardesty, K Cameron Falkner, Russell A Prough, Appakalai N Balamurugan, Sri Prakash Mokshagundam, Suresh T Chari, Matthew C Cave. Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes.
Toxicology and applied pharmacology.
2019 01; 363(?):22-33. doi:
10.1016/j.taap.2018.10.011. [PMID: 30312631] - Robin Mesnage, Martina Biserni, Sucharitha Balu, Clément Frainay, Nathalie Poupin, Fabien Jourdan, Eva Wozniak, Theodoros Xenakis, Charles A Mein, Michael N Antoniou. Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126.
Archives of toxicology.
2018 08; 92(8):2533-2547. doi:
10.1007/s00204-018-2235-7. [PMID: 29947894] - Gopi S Gadupudi, Benjamin A Elser, Fabian A Sandgruber, Xueshu Li, Katherine N Gibson-Corley, Larry W Robertson. PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 06; 163(2):440-453. doi:
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Environmental pollution (Barking, Essex : 1987).
2018 Jun; 237(?):508-514. doi:
10.1016/j.envpol.2018.02.079. [PMID: 29522993] - Josiah E Hardesty, Laila Al-Eryani, Banrida Wahlang, K Cameron Falkner, Hongxue Shi, Jian Jin, Brad J Vivace, Brian P Ceresa, Russell A Prough, Matthew C Cave. Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 04; 162(2):622-634. doi:
10.1093/toxsci/kfy004. [PMID: 29329451] - Michael C Petriello, J Anthony Brandon, Jessie Hoffman, Chunyan Wang, Himi Tripathi, Ahmed Abdel-Latif, Xiang Ye, Xiangan Li, Liping Yang, Eun Lee, Sony Soman, Jazmyne Barney, Banrida Wahlang, Bernhard Hennig, Andrew J Morris. Dioxin-like PCB 126 Increases Systemic Inflammation and Accelerates Atherosclerosis in Lean LDL Receptor-Deficient Mice.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 04; 162(2):548-558. doi:
10.1093/toxsci/kfx275. [PMID: 29216392] - Hongyan Xu, Caixia Li, Pacharaporn Suklai, Qinghua Zeng, Raymond Chong, Zhiyuan Gong. Differential sensitivities to dioxin-like compounds PCB 126 and PeCDF between Tg(cyp1a:gfp) transgenic medaka and zebrafish larvae.
Chemosphere.
2018 Feb; 192(?):24-30. doi:
10.1016/j.chemosphere.2017.10.130. [PMID: 29091793] - R G Ahmed, A W El-Gareib, H M Shaker. Gestational 3,3',4,4',5-pentachlorobiphenyl (PCB 126) exposure disrupts fetoplacental unit: Fetal thyroid-cytokines dysfunction.
Life sciences.
2018 Jan; 192(?):213-220. doi:
10.1016/j.lfs.2017.11.033. [PMID: 29175438] - Banrida Wahlang, Jazmyne Barney, Brendan Thompson, Chunyan Wang, Omer M Hamad, Jessie B Hoffman, Michael C Petriello, Andrew J Morris, Bernhard Hennig. Editor's Highlight: PCB126 Exposure Increases Risk for Peripheral Vascular Diseases in a Liver Injury Mouse Model.
Toxicological sciences : an official journal of the Society of Toxicology.
2017 Dec; 160(2):256-267. doi:
10.1093/toxsci/kfx180. [PMID: 28973532] - L Manzini, S Halwachs, F Girolami, P Badino, W Honscha, C Nebbia. Interaction of mammary bovine ABCG2 with AFB1 and its metabolites and regulation by PCB 126 in a MDCKII in vitro model.
Journal of veterinary pharmacology and therapeutics.
2017 Dec; 40(6):591-598. doi:
10.1111/jvp.12397. [PMID: 28198024] - Izabela Kania-Korwel, Xianai Wu, Kai Wang, Hans-Joachim Lehmler. Identification of lipidomic markers of chronic 3,3',4,4',5-pentachlorobiphenyl (PCB 126) exposure in the male rat liver.
Toxicology.
2017 09; 390(?):124-134. doi:
10.1016/j.tox.2017.09.005. [PMID: 28890136] - Yu Bon Man, Ka Lai Chow, Guan Hua Xing, Janet Kit Yan Chan, Sheng Chun Wu, Ming Hung Wong. A pilot study on health risk assessment based on body loadings of PCBs of lactating mothers at Taizhou, China, the world's major site for recycling transformers.
Environmental pollution (Barking, Essex : 1987).
2017 Aug; 227(?):364-371. doi:
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Toxicology and applied pharmacology.
2017 04; 321(?):1-17. doi:
10.1016/j.taap.2017.02.006. [PMID: 28213091] - Natalie A Chapados, Marie-Pier Boucher. Liver metabolic disruption induced after a single exposure to PCB126 in rats.
Environmental science and pollution research international.
2017 Jan; 24(2):1854-1861. doi:
10.1007/s11356-016-7939-8. [PMID: 27796995] - Artur Radomyski, Elisa Giubilato, Philippe Ciffroy, Andrea Critto, Céline Brochot, Antonio Marcomini. Modelling ecological and human exposure to POPs in Venice lagoon - Part II: Quantitative uncertainty and sensitivity analysis in coupled exposure models.
The Science of the total environment.
2016 Nov; 569-570(?):1635-1649. doi:
10.1016/j.scitotenv.2016.07.057. [PMID: 27432731] - Saimi Tokunaga, Bruce R Woodin, John J Stegeman. Plant lignan secoisolariciresinol suppresses pericardial edema caused by dioxin-like compounds in developing zebrafish: Implications for suppression of morphological abnormalities.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2016 Oct; 96(?):160-6. doi:
10.1016/j.fct.2016.07.012. [PMID: 27427306] - Gopi S Gadupudi, Aloysius J Klingelhutz, Larry W Robertson. Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity.
Chemical research in toxicology.
2016 09; 29(9):1504-9. doi:
10.1021/acs.chemrestox.6b00172. [PMID: 27509375] - Karyne Bellehumeur, Dominique Lapointe, Steven J Cooke, Thomas W Moon. Exposure to sublethal levels of PCB-126 impacts fuel metabolism and swimming performance in rainbow trout.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
2016 Sep; 199(?):97-104. doi:
10.1016/j.cbpb.2016.01.005. [PMID: 26803990] - Xianai Wu, Jun Yang, Christophe Morisseau, Larry W Robertson, Bruce Hammock, Hans-Joachim Lehmler. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats.
Toxicological sciences : an official journal of the Society of Toxicology.
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The Journal of nutritional biochemistry.
2016 07; 33(?):145-53. doi:
10.1016/j.jnutbio.2016.03.016. [PMID: 27155921] - Rodrigo Azevedo Loiola, Fabyana Maria Dos Anjos, Ana Lúcia Shimada, Wesley Soares Cruz, Carine Cristiane Drewes, Stephen Fernandes Rodrigues, Karina Helena Morais Cardozo, Valdemir Melechco Carvalho, Ernani Pinto, Sandra Helena Farsky. Long-term in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans.
Scientific reports.
2016 06; 6(?):27882. doi:
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Environmental science and pollution research international.
2016 Feb; 23(3):2108-18. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2016 Jan; 149(1):98-110. doi:
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Toxicology.
2015 Dec; 338(?):1-7. doi:
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Marine biotechnology (New York, N.Y.).
2015 Dec; 17(6):831-40. doi:
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Scientific reports.
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Chemical research in toxicology.
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The Science of the total environment.
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Environmental science and pollution research international.
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Toxicology letters.
2014 Apr; 226(1):43-52. doi:
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The Journal of nutritional biochemistry.
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Environment international.
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Environmental health perspectives.
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Chemical research in toxicology.
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Archives of toxicology.
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Toxicology.
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Chemosphere.
2012 May; 87(9):1057-62. doi:
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Toxicology letters.
2012 Mar; 209(3):291-8. doi:
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PloS one.
2012; 7(5):e37103. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2011 Dec; 41(12):1031-43. doi:
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Toxicology.
2011 Sep; 287(1-3):113-23. doi:
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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2011 Jun; 154(1):42-55. doi:
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Environmental research.
2011 Apr; 111(3):337-47. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2011 Feb; 25(1):335-42. doi:
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Toxicologic pathology.
2010 Dec; 38(7):1037-50. doi:
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Environmental health perspectives.
2010 Dec; 118(12):1735-42. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2010 Sep; 117(1):36-44. doi:
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Environmental health : a global access science source.
2010 Aug; 9(?):51. doi:
10.1186/1476-069x-9-51. [PMID: 20731829] - Maria E Jönsson, Kai Gao, Jan A Olsson, Jared V Goldstone, Ingvar Brandt. Induction patterns of new CYP1 genes in environmentally exposed rainbow trout.
Aquatic toxicology (Amsterdam, Netherlands).
2010 Jul; 98(4):311-21. doi:
10.1016/j.aquatox.2010.03.003. [PMID: 20371123] - Bruno Soffientino, Diane E Nacci, Jennifer L Specker. Effects of the dioxin-like PCB 126 on larval summer flounder (Paralichthys dentatus).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2010 Jun; 152(1):9-17. doi:
10.1016/j.cbpc.2010.02.006. [PMID: 20170748] - Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa. A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Jan; 38(1):150-6. doi:
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Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2010; 45(8):932-7. doi:
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Bulletin of environmental contamination and toxicology.
2010 Jan; 84(1):66-70. doi:
10.1007/s00128-009-9890-6. [PMID: 19806282] - Nancy B Hopf, Martha A Waters, Avima M Ruder, Mary M Prince. Development of a retrospective job exposure matrix for PCB-exposed workers in capacitor manufacturing.
Journal of occupational health.
2010; 52(4):199-208. doi:
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Toxicology letters.
2009 Jun; 187(2):63-8. doi:
10.1016/j.toxlet.2009.01.030. [PMID: 19429246] - Daniela Cocchi, Giovanni Tulipano, Alessandra Colciago, Valeria Sibilia, Francesca Pagani, Daniela Viganò, Tiziana Rubino, Daniela Parolaro, Patrizia Bonfanti, Anita Colombo, Fabio Celotti. Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring.
Toxicology and applied pharmacology.
2009 Jun; 237(2):127-36. doi:
10.1016/j.taap.2009.03.008. [PMID: 19327374] - Zuzana Majkova, Eric Smart, Michal Toborek, Bernhard Hennig. Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent.
Toxicology and applied pharmacology.
2009 May; 237(1):1-7. doi:
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Environmental health perspectives.
2009 Apr; 117(4):568-73. doi:
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Journal of toxicology and environmental health. Part A.
2009; 72(3-4):164-72. doi:
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Chemico-biological interactions.
2008 Nov; 176(2-3):71-8. doi:
10.1016/j.cbi.2008.08.007. [PMID: 18786521] - Edwin M Foekema, Charlotte M Deerenberg, Albertinka J Murk. Prolonged ELS test with the marine flatfish sole (Solea solea) shows delayed toxic effects of previous exposure to PCB 126.
Aquatic toxicology (Amsterdam, Netherlands).
2008 Nov; 90(3):197-203. doi:
10.1016/j.aquatox.2008.08.015. [PMID: 18945500] - Richard M Green, Nikolas J Hodges, J Kevin Chipman, Michael R O'Donovan, Mark Graham. Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls.
Mutagenesis.
2008 Nov; 23(6):457-63. doi:
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Toxicology.
2008 May; 247(1):55-60. doi:
10.1016/j.tox.2008.02.002. [PMID: 18367304] - Shu Zhang, Craig Rowlands, Stephen Safe. Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay.
Toxicology and applied pharmacology.
2008 Mar; 227(2):196-206. doi:
10.1016/j.taap.2007.10.019. [PMID: 18048071] - Jason Matthews, Björn Wihlén, Nina Heldring, Laura MacPherson, Luisa Helguero, Eckardt Treuter, Lars-Arne Haldosén, Jan-Ake Gustafsson. Co-planar 3,3',4,4',5-pentachlorinated biphenyl and non-co-planar 2,2',4,6,6'-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor alpha to aryl hydrocarbon receptor target genes.
The Biochemical journal.
2007 Sep; 406(2):343-53. doi:
10.1042/bj20070585. [PMID: 17511620] - Duk-Hee Lee, David R Jacobs, Miquel Porta. Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder.
Journal of epidemiology and community health.
2007 Jul; 61(7):591-6. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2007 Jun; 97(2):308-17. doi:
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The Tohoku journal of experimental medicine.
2007 Jun; 212(2):151-7. doi:
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Toxicology and applied pharmacology.
2007 May; 221(1):29-41. doi:
10.1016/j.taap.2007.02.017. [PMID: 17445853] - Suzanne Côté, Pierre Ayotte, Sylvie Dodin, Claudine Blanchet, Gert Mulvad, Henning S Petersen, Suzanne Gingras, Eric Dewailly. Plasma organochlorine concentrations and bone ultrasound measurements: a cross-sectional study in peri-and postmenopausal Inuit women from Greenland.
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2006 Dec; 5(?):33. doi:
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National Toxicology Program technical report series.
2006 Nov; ?(531):1-218. doi:
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National Toxicology Program technical report series.
2006 Sep; ?(526):1-180. doi:
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National Toxicology Program technical report series.
2006 Aug; ?(530):1-258. doi:
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National Toxicology Program technical report series.
2006 May; ?(529):4-168. doi:
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Life sciences.
2006 Apr; 78(19):2219-25. doi:
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