2,2',3,3',6,6'-Hexachlorobiphenyl (BioDeep_00000009860)

 

Secondary id: BioDeep_00001874446

human metabolite blood metabolite Industrial Pollutants Volatile Flavor Compounds


代谢物信息卡片


1,2,4-trichloro-3-(2,3,6-trichlorophenyl)benzene

化学式: C12H4Cl6 (357.8444164)
中文名称: 多氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C(=C1Cl)C2=C(C=CC(=C2Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C12H4Cl6/c13-5-1-3-7(15)11(17)9(5)10-6(14)2-4-8(16)12(10)18/h1-4H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

6 个代谢物同义名

1,2,4-trichloro-3-(2,3,6-trichlorophenyl)benzene; 2,3,6,2,3,6-Hexachlorobiphenyl; 2,2,3,3,6,6-HEXACHLOROBIPHENYL; PCB-136; PCB 136; 2,2',3,3',6,6'-Hexachlorobiphenyl



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • J Sanz-Landaluze, M Pena-Abaurrea, R Muñoz-Olivas, C Cámara, L Ramos. Zebrafish (Danio rerio) eleutheroembryo-based procedure for assessing bioaccumulation. Environmental science & technology. 2015 Feb; 49(3):1860-9. doi: 10.1021/es504685c. [PMID: 25590991]
  • Xianai Wu, Christopher Barnhart, Pamela J Lein, Hans-Joachim Lehmler. Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice. Environmental science & technology. 2015 Jan; 49(1):616-25. doi: 10.1021/es504766p. [PMID: 25420130]
  • Guangshu Zhai, Dingfei Hu, Hans-Joachim Lehmler, Jerald L Schnoor. Enantioselective biotransformation of chiral PCBs in whole poplar plants. Environmental science & technology. 2011 Mar; 45(6):2308-16. doi: 10.1021/es1033662. [PMID: 21329345]
  • I Kania-Korwel, K C Hornbuckle, L W Robertson, H-J Lehmler. Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Feb; 46(2):637-44. doi: 10.1016/j.fct.2007.09.072. [PMID: 17950514]
  • Izabela Kania-Korwel, Keri C Hornbuckle, Larry W Robertson, Hans-Joachim Lehmler. Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. Environmental toxicology and chemistry. 2008 Feb; 27(2):299-305. doi: 10.1897/07-359r.1. [PMID: 18348647]
  • R J Aulerich, S J Bursian, W J Breslin, B A Olson, R K Ringer. Toxicological manifestations of 2,4,5,2',4',5'-, 2,3,6,2',3',6'-, and 3,4,5,3',4',5'-hexachlorobiphenyl and Aroclor 1254 in mink. Journal of toxicology and environmental health. 1985; 15(1):63-79. doi: 10.1080/15287398509530636. [PMID: 3920403]
  • L S Birnbaum. Distribution and excretion of 2,3,6,2',3',6'- and 2,4,5,2',4',5'-hexachlorobiphenyl in senescent rats. Toxicology and applied pharmacology. 1983 Sep; 70(2):262-72. doi: 10.1016/0041-008x(83)90102-3. [PMID: 6414105]
  • I G Sipes, M L Slocumb, H S Chen, D E Carter. 2,3,6,2',3',6'-hexachlorobiphenyl: distribution, metabolism, and excretion in the dog and the monkey. Toxicology and applied pharmacology. 1982 Feb; 62(2):317-24. doi: 10.1016/0041-008x(82)90130-2. [PMID: 6800067]
  • N M Morales, H B Matthews. In vivo binding of 2,3,6,2',3',6'-hexachlorobiphenyl and 2,4,5,2',4',5'-hexachlorobiphenyl to mouse liver macromolecules. Chemico-biological interactions. 1979 Sep; 27(1):99-110. doi: 10.1016/0009-2797(79)90153-4. [PMID: 113111]