Pentachloronitrobenzene (BioDeep_00000009834)
Secondary id: BioDeep_00001873653
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
1,2,3,4,5-pentachloro-6-nitrobenzene
化学式: C6Cl5NO2 (292.837169)
中文名称: 甲醇中五氯硝基苯溶液
谱图信息:
最多检出来源 Homo sapiens(blood) 94.74%
分子结构信息
SMILES: C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)[N+](=O)[O-]
InChI: InChI=1S/C6Cl5NO2/c7-1-2(8)4(10)6(12(13)14)5(11)3(1)9
描述信息
D016573 - Agrochemicals
D010575 - Pesticides
同义名列表
23 个代谢物同义名
1,2,3,4,5-pentachloro-6-nitrobenzene; 2,3,4,5,6-Pentachloronitrobenzene; Pentachloronitrobenzene; Nitropentachlorobenzene; Pentachlornitrobenzol; Terrachlor; Quintozene; Earthcide; Brassicol; Fungiclor; Terraclor; Phomasan; Batrilex; Tilcarex; Botrilex; Terrafun; Pentagen; Folosan; Avicol; Fartox; PKHNC; PCNB; Quintozene
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:34908
- KEGG: C14338
- PubChem: 6720
- HMDB: HMDB0256248
- Metlin: METLIN69976
- ChEMBL: CHEMBL468759
- Wikipedia: Pentachloronitrobenzene
- chemspider: 6464
- CAS: 82-68-8
- PMhub: MS000023653
- PubChem: 17395338
- NIKKAJI: J3.869E
- KNApSAcK: 34908
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ming Li, Guanghui Xu, Na Guo, Na Zheng, Weihua Dong, Xiao Li, Yong Yu. Influences and mechanisms of nanoparticles on pentachloronitrobenzene accumulation by earthworms.
Environmental science and pollution research international.
2021 Oct; 28(37):51471-51479. doi:
10.1007/s11356-021-14368-6. [PMID: 33983610] - Ling Zhao, Yan Li, Wenjie Ren, Yang Huang, Xiaomi Wang, Zhaocong Fu, Wenting Ma, Ying Teng, Yongming Luo. Pesticide residues in soils planted with Panax notoginseng in south China, and their relationships in Panax notoginseng and soil.
Ecotoxicology and environmental safety.
2020 Sep; 201(?):110783. doi:
10.1016/j.ecoenv.2020.110783. [PMID: 32534333] - Yanrong Kuai, Xiaobo Gao, Huixia Yang, Haiyan Luo, Yang Xu, Chenchen Liu, Haiying Yu, Yihan Wang, Chen Zhang, Xu Ma, Cailing Lu. Pentachloronitrobenzene alters progesterone production and primordial follicle recruitment in cultured granulosa cells and rat ovary†.
Biology of reproduction.
2020 02; 102(2):511-520. doi:
10.1093/biolre/ioz195. [PMID: 31616914] - Ming Li, Guanghui Xu, Rui Yu, Yang Wang, Yong Yu. Uptake and accumulation of pentachloronitrobenzene in pak choi and the human health risk.
Environmental geochemistry and health.
2020 Jan; 42(1):109-120. doi:
10.1007/s10653-019-00305-7. [PMID: 31037581] - Yue Geng, Linjie Jiang, Hongxin Jiang, Lu Wang, Yi Peng, Ce Wang, Xiaomeng Shi, Jing Gu, Yuehua Wang, Jiachao Zhu, Lihong Dai, Yaping Xu, Xiaowei Liu. Assessment of heavy metals, fungicide quintozene and its hazardous impurity residues in medical Panax notoginseng (Burk) F.H.Chen root.
Biomedical chromatography : BMC.
2019 Feb; 33(2):e4378. doi:
10.1002/bmc.4378. [PMID: 30176061] - Y Wang, C Wang, A Li, J Gao. Biodegradation of pentachloronitrobenzene by Arthrobacter nicotianae DH19.
Letters in applied microbiology.
2015 Oct; 61(4):403-10. doi:
10.1111/lam.12476. [PMID: 26250405] - Cora Lilia Alvarez, Stefania Somma, Robert H Proctor, Gaetano Stea, Giuseppina Mulè, Antonio F Logrieco, Virginia Fernandez Pinto, Antonio Moretti. Genetic diversity in Fusarium graminearum from a major wheat-producing region of Argentina.
Toxins.
2011 10; 3(10):1294-309. doi:
10.3390/toxins3101294. [PMID: 22069697] - Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
Toxicology.
2011 Feb; 280(3):77-87. doi:
10.1016/j.tox.2010.11.008. [PMID: 21115097] - Zi-Wu Guo, Shuang-Lin Chen, Jiang-Hua Xiao. Organochlorine pesticide residues in bamboo shoot.
Journal of the science of food and agriculture.
2011 Feb; 91(3):593-6. doi:
10.1002/jsfa.4233. [PMID: 21218497] - Heng Mei Hsuan, Baharuddin Salleh, Latiffah Zakaria. Molecular identification of Fusarium species in Gibberella fujikuroi species complex from rice, sugarcane and maize from Peninsular Malaysia.
International journal of molecular sciences.
2011; 12(10):6722-32. doi:
10.3390/ijms12106722. [PMID: 22072914] - Khosrow Chehri, Saeed Tamadoni Jahromi, Kasa R N Reddy, Saeed Abbasi, Baharuddin Salleh. Occurrence of Fusarium spp. and fumonisins in stored wheat grains marketed in Iran.
Toxins.
2010 12; 2(12):2816-23. doi:
10.3390/toxins2122816. [PMID: 22069576] - L Alborch, M R Bragulat, F J Cabañes. Comparison of two selective culture media for the detection of Fusarium infection in conventional and transgenic maize kernels.
Letters in applied microbiology.
2010 Mar; 50(3):270-5. doi:
10.1111/j.1472-765x.2009.02787.x. [PMID: 20070505] - Jian Xue, Lili Hao, Fei Peng. Residues of 18 organochlorine pesticides in 30 traditional Chinese medicines.
Chemosphere.
2008 Apr; 71(6):1051-5. doi:
10.1016/j.chemosphere.2007.11.014. [PMID: 18160094] - Lili Hao, Jian Xue. Multiresidue analysis of 18 organochlorine pesticides in traditional chinese medicine.
Journal of chromatographic science.
2006 Sep; 44(8):518-22. doi:
10.1093/chromsci/44.8.518. [PMID: 16959129] - J-M Durgnat, J Heuser, D Andrey, C Perrin. Quality and safety assessment of ginseng extracts by determination of the contents of pesticides and metals.
Food additives and contaminants.
2005 Dec; 22(12):1224-30. doi:
10.1080/02652030500199439. [PMID: 16356886] - Rajiv Bhatia, Rita Shiau, Myrto Petreas, June M Weintraub, Lili Farhang, Brenda Eskenazi. Organochlorine pesticides and male genital anomalies in the child health and development studies.
Environmental health perspectives.
2005 Feb; 113(2):220-4. doi:
10.1289/ehp.7382. [PMID: 15687061] - Stéphane Bayen, Yinhan Gong, Hong Soon Chin, Hian Kee Lee, Yong Eu Leong, Jeffrey Philip Obbard. Androgenic and estrogenic response of green mussel extracts from Singapore's coastal environment using a human cell-based bioassay.
Environmental health perspectives.
2004 Nov; 112(15):1467-71. doi:
10.1289/ehp.6990. [PMID: 15531429] - G I Souto, O S Correa, M S Montecchia, N L Kerber, N L Pucheu, M Bachur, A F García. Genetic and functional characterization of a Bacillus sp. strain excreting surfactin and antifungal metabolites partially identified as iturin-like compounds.
Journal of applied microbiology.
2004; 97(6):1247-56. doi:
10.1111/j.1365-2672.2004.02408.x. [PMID: 15546416] - S Gielen, R Aerts, B Seels. Development of a selective medium for the determination of the spore concentrations of Botrytis cinerea in the air.
Communications in agricultural and applied biological sciences.
2003; 68(4 Pt B):685-93. doi:
". [PMID: 15151304] - Vladimir Vujanovic, Chantal Hamel, Suha Jabaji-Hare, Marc St-Arnaud. Development of a selective myclobutanil agar (MBA) medium for the isolation of Fusarium species from asparagus fields.
Canadian journal of microbiology.
2002 Sep; 48(9):841-7. doi:
10.1139/w02-082. [PMID: 12455616] - H Huang. [Determination of residues of organic chloride pesticide in Chinese medicinal materials with capillary gas chromatography].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2001 Apr; 24(4):239-41. doi:
". [PMID: 12587153] - C Michielsen, S Boeren, I Rietjens, F van Mil, J Vos, N Bloksma. The mercapturic acid biotransformation pathway of hexachlorobenzene is not involved in the induction of splenomegaly, or skin and lung lesions in the Brown Norway rat.
Archives of toxicology.
2000 Dec; 74(10):609-17. doi:
10.1007/s002040000166. [PMID: 11201668] - D E Wedge, D G Nagle. A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens.
Journal of natural products.
2000 Aug; 63(8):1050-4. doi:
10.1021/np990628r. [PMID: 10978195] - G L Larsen, J K Huwe, J E Bakke. Intermediary metabolism of pentachloronitrobenzene in the control and germ-free rat and rat with cannulated bile ducts.
Xenobiotica; the fate of foreign compounds in biological systems.
1998 Oct; 28(10):973-84. doi:
10.1080/004982598239038. [PMID: 9849644] - M Shun, X Lu. [The preventing and control of ginseng Rhizoctonia solani with nymexazol].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
1997 Feb; 20(2):56-8. doi:
". [PMID: 12572480] - J To-Figueras, J Gómez-Catalán, M Rodamilans, J Corbella. Studies on sex differences in excretion of sulphur derivatives of hexachlorobenzene and pentachloronitrobenzene by rats.
Toxicology letters.
1991 Apr; 56(1-2):87-94. doi:
10.1016/0378-4274(91)90093-l. [PMID: 2017788] - I Scheunert, F Korte, D Reiml. [Studies on the administration of plant pesticides on the plant/soil system in lysimeters using 14C-marked substances with special reference to leaching behavior].
Schriftenreihe des Vereins fur Wasser-, Boden- und Lufthygiene.
1987; 68(?):313-34. doi:
". [PMID: 3589544] - M Ando, S Hirano, Y Itoh. Transfer of hexachlorobenzene (HCB) from mother to newborn baby through placenta and milk.
Archives of toxicology.
1985 Jan; 56(3):195-200. doi:
10.1007/bf00333426. [PMID: 3977600] - G Renner, P T Nguyen. Biotransformation of derivatives of the fungicides pentachloronitrobenzene and hexachlorobenzene in mammals.
Xenobiotica; the fate of foreign compounds in biological systems.
1984 Sep; 14(9):693-704. doi:
10.3109/00498258409151467. [PMID: 6516442] - A G Smith, J E Francis. Evidence for the active renal secretion of S-pentachlorophenyl-N-acetyl-L-cysteine by female rats.
Biochemical pharmacology.
1983 Dec; 32(24):3797-801. doi:
10.1016/0006-2952(83)90152-1. [PMID: 6661253] - M Kamal, I Scheunert, F Körte. Mass balance of 14C-pentachloronitrobenzene and metabolites in a closed, aerated soil-plant or soil-system.
Bulletin of environmental contamination and toxicology.
1983 Nov; 31(5):559-65. doi:
10.1007/bf01605475. [PMID: 6640153] - P W Aschbacher, V J Feil. Metabolism of pentachloronitrobenzene by goats and sheep.
Journal of agricultural and food chemistry.
1983 Nov; 31(6):1150-8. doi:
10.1021/jf00120a005. [PMID: 6655138] - P L La Celle, B D Smith. Biochemical factors influencing erythrocyte deformability and capillary entrance phenomena.
Scandinavian journal of clinical and laboratory investigation. Supplementum.
1981; 156(?):145-9. doi:
10.3109/00365518109097447. [PMID: 6948376] - G Renner. Metabolic studies on pentachloronitrobenzene (PCNB) in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
1980 Jul; 10(7-8):537-50. doi:
10.3109/00498258009033788. [PMID: 7445521] - J S Dunn, P B Bush, N H Booth, R L Farrell, D M Thomason, D D Goetsch. Tissue residues from feeding pentachloronitrobenzene (quintozene) to White Leghorn chickens.
American journal of veterinary research.
1979 Sep; 40(9):1227-30. doi:
. [PMID: 525926] - J S Dunn, P B Bush, N H Booth, R L Farrell, D M Thomason, D D Goetsch. Effect of pentachloronitrobenzene upon egg production, hatchability, and residue accumulation in the tissues of White Leghorn hens.
Toxicology and applied pharmacology.
1979 May; 48(3):425-33. doi:
10.1016/0041-008x(79)90426-5. [PMID: 473189] - W F Müller, I Scheunert, K Rozman, W Kögel, D Freitag, E Richter, F Coulston, F Korte. Comparative metabolism of hexachlorobenzene and pentachloronitrobenzene in plants, rats, and rhesus monkeys.
Ecotoxicology and environmental safety.
1978 Dec; 2(3-4):437-45. doi:
10.1016/s0147-6513(78)80017-7. [PMID: 109270] - J S Dunn, N H Booth, P B Bush, R L Farrell, D Thomason, D D Goetsch. The accumulation and elimination of tissue residues after feeding pentachloronitrobenzene to White Leghorn cockerels.
Poultry science.
1978 Nov; 57(6):1533-8. doi:
10.3382/ps.0571533. [PMID: 751034] - L E ST JOHN, J W AMMERING, D G WAGNER, R G WARNER, D J LISK. FATE OF 4,6-DINITRO-2-ISOBUTYLPHENOL, 2-CHLORO-4,6-BIS-(ETHYLAMINO)-S-TRIAZINE, AND PENTACHLORONITROBENZENE IN THE DAIRY COW.
Journal of dairy science.
1965 Apr; 48(?):502-3. doi:
10.3168/jds.s0022-0302(65)88263-7. [PMID: 14282452]