(7E)-7-[(Z)-(4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene)hydrazinylidene]-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol (BioDeep_00000929601)
代谢物信息卡片
化学式: C38H42N4O6 (650.3104)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=CCN1CCC23C4C(=NN=C5CCC6(C7CC8=C9C6(C5OC9=C(C=C8)O)CCN7CC=C)O)CCC2(C1CC1=C3C(=C(C=C1)O)O4)O
InChI: InChI=1S/C38H42N4O6/c1-3-15-41-17-13-35-29-21-5-7-25(43)31(29)47-33(35)23(9-11-37(35,45)27(41)19-21)39-40-24-10-12-38(46)28-20-22-6-8-26(44)32-30(22)36(38,34(24)48-32)14-18-42(28)16-4-2/h3-8,27-28,33-34,43-46H,1-2,9-20H2/b39-23-,40-24+
描述信息
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- E Dobek, K Górski, K Romanowicz, T Misztal. Different types of opioid receptors involved in the suppression of LH secretion in lactating sheep.
Animal reproduction science.
2013 Sep; 141(1-2):62-7. doi:
10.1016/j.anireprosci.2013.07.006. [PMID: 23953813] - K Górski, T Misztal, E Dobek, E Molik, K Romanowicz. Regulation of growth hormone secretion in nursing ewes: an involvement of μ-receptor subtype.
Reproduction in domestic animals = Zuchthygiene.
2012 Oct; 47(5):746-51. doi:
10.1111/j.1439-0531.2011.01953.x. [PMID: 22212243] - T Misztal, D Tomaszewska-Zaremba, K Górski, K Romanowicz. Opioid-salsolinol relationship in the control of prolactin release during lactation.
Neuroscience.
2010 Nov; 170(4):1165-71. doi:
10.1016/j.neuroscience.2010.08.011. [PMID: 20708656] - Juei-Tang Cheng, Ching-Chiu Huang, I-Min Liu, Thing-Fong Tzeng, Chih Jen Chang. Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats.
Diabetes.
2006 Mar; 55(3):819-25. doi:
10.2337/diabetes.55.03.06.db05-0934. [PMID: 16505249] - J Gutkowska, S Mukaddam-Daher, M Jankowski, P W Schiller. The cardiovascular and renal effects of the potent and highly selective mu opioid agonist [Dmt1]DALDA.
Journal of cardiovascular pharmacology.
2004 Dec; 44(6):651-8. doi:
10.1097/00005344-200412000-00005. [PMID: 15550783] - J T Cheng, I M Liu, T F Tzeng, C C Tsai, T Y Lai. Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2002 Oct; 34(10):570-6. doi:
10.1055/s-2002-35418. [PMID: 12439785] - Jaung-Geng Lin, Shih-Liang Chang, Juei-Tang Cheng. Release of beta-endorphin from adrenal gland to lower plasma glucose by the electroacupuncture at Zhongwan acupoint in rats.
Neuroscience letters.
2002 Jun; 326(1):17-20. doi:
10.1016/s0304-3940(02)00331-2. [PMID: 12052528] - J T Cheng, I M Liu, T C Chi, T F Tzeng, F H Lu, C J Chang. Plasma glucose-lowering effect of tramadol in streptozotocin-induced diabetic rats.
Diabetes.
2001 Dec; 50(12):2815-21. doi:
10.2337/diabetes.50.12.2815. [PMID: 11723065] - G Bonner, F Meng, H Akil. Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
European journal of pharmacology.
2000 Sep; 403(1-2):37-44. doi:
10.1016/s0014-2999(00)00578-1. [PMID: 10969141] - T Sasaki, K Arakawa, K Shimada, N Saito. The effects of highly selective opioid receptor antagonists on the release of arginine vasotocin induced by hyperosmotic stimulation and angiotensin II injection.
General and comparative endocrinology.
2000 Jun; 118(3):365-72. doi:
10.1006/gcen.2000.7470. [PMID: 10843787] - I M Liu, T C Chi, Y C Chen, F H Lu, J T Cheng. Activation of opioid mu-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats.
Neuroscience letters.
1999 Apr; 265(3):183-6. doi:
10.1016/s0304-3940(99)00226-8. [PMID: 10327161] - N Imai, M Kashiki, P D Woolf, C S Liang. Comparison of cardiovascular effects of mu- and delta-opioid receptor antagonists in dogs with congestive heart failure.
The American journal of physiology.
1994 Sep; 267(3 Pt 2):H912-7. doi:
10.1152/ajpheart.1994.267.3.h912. [PMID: 8092295] - R M Eisenberg. TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis.
Pharmacology, biochemistry, and behavior.
1994 Apr; 47(4):943-6. doi:
10.1016/0091-3057(94)90300-x. [PMID: 8029266] - R M Eisenberg. DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
The Journal of pharmacology and experimental therapeutics.
1993 Aug; 266(2):985-91. doi:
. [PMID: 8394926] - S Rivest, P M Plotsky, C Rivier. CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: possible involvement of opioid receptors.
Neuroendocrinology.
1993; 57(2):236-46. doi:
10.1159/000126365. [PMID: 8389996] - M H Baumann, J Rabii. Inhibition of suckling-induced prolactin release by mu- and kappa-opioid antagonists.
Brain research.
1991 Dec; 567(2):224-30. doi:
10.1016/0006-8993(91)90799-2. [PMID: 1667901] - S Sakamoto, C S Liang. Opiate receptor inhibition improves the blunted baroreflex function in conscious dogs with right-sided congestive heart failure.
Circulation.
1989 Oct; 80(4):1010-5. doi:
10.1161/01.cir.80.4.1010. [PMID: 2551535]
