7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (BioDeep_00000925335)

   


代谢物信息卡片


7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

化学式: C22H22N6O7S2 (546.0991342)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-]
InChI: InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13+



数据库引用编号

1 个数据库交叉引用编号

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相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Nabih A Baeshen, Abdulaziz O Albeshri, Naseebh N Baeshen, Roba Attar, Alaa Karkashan, Basma Abbas, Thamer A Bouback, Abdullah A Aljaddawi, Mohammed Y Refai, Hayam S Abdelkader, Abdullah Al Tamim, Abdullah Alowaifeer, Firoz Ahmed, Mohammed N Baeshen. In silico screening of some compounds derived from the desert medicinal plant Rhazya stricta for the potential treatment of COVID-19. Scientific reports. 2022 Jul; 12(1):11120. doi: 10.1038/s41598-022-15288-2. [PMID: 35778482]
  • Nikhil Sadashiv Shetty, Arvind Karikal, Sharanya Menon Radhakrishnan. Melioidosis: an unusual diagnosis for deep temporal and masticatory space infection following trauma. BMJ case reports. 2022 Jun; 15(6):. doi: 10.1136/bcr-2022-248866. [PMID: 35732363]
  • Petr Tůma, Martin Jaček, Blanka Sommerová, Pavel Dlouhý, Radka Jarošíková, Jitka Husáková, Veronika Wosková, Vladimíra Fejfarová. Monitoring of amoxicilline and ceftazidime in the microdialysate of diabetic foot and serum by capillary electrophoresis with contactless conductivity detection. Electrophoresis. 2022 06; 43(11):1129-1139. doi: 10.1002/elps.202100366. [PMID: 35072285]
  • Laetissia Amirouche, Alexandra Cerulli-Kanellopoulos, Sébastien Landry, Véronique C LeBlanc, Ghislain Léger. Ceftazidime-Induced Neurotoxicity in an 80-Year-Old Female With Renal Dysfunction: A Case Report. Journal of pharmacy practice. 2022 Jun; 35(3):482-487. doi: 10.1177/0897190021989931. [PMID: 33517818]
  • Elkin V Lemos-Luengas, Sixta Rentería-Valoyes, Paola Cárdenas-Isaza, Jorge A Ramos-Castaneda. In vitro activity of ceftazidime/avibactam against Gram-negative strains in Colombia 2014-2018. Journal of global antimicrobial resistance. 2022 Jun; 29(?):141-146. doi: 10.1016/j.jgar.2022.02.018. [PMID: 35257971]
  • Fernando L Gordillo Altamirano, Xenia Kostoulias, Dinesh Subedi, Denis Korneev, Anton Y Peleg, Jeremy J Barr. Phage-antibiotic combination is a superior treatment against Acinetobacter baumannii in a preclinical study. EBioMedicine. 2022 Jun; 80(?):104045. doi: 10.1016/j.ebiom.2022.104045. [PMID: 35537278]
  • Ben Vaknin, Nancy Bishouty, Amos Adler. Microbiological and clinical changes following the transition to the 2010 revised CLSI breakpoints for extended-spectrum cephalosporin in Enterobacterales. Diagnostic microbiology and infectious disease. 2022 May; 103(1):115654. doi: 10.1016/j.diagmicrobio.2022.115654. [PMID: 35219970]
  • G Bianco, M Boattini, A Bondi, S Comini, T Zaccaria, R Cavallo, C Costa. Outbreak of ceftazidime-avibactam resistant Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae in a COVID-19 intensive care unit, Italy: urgent need for updated diagnostic protocols of surveillance cultures. The Journal of hospital infection. 2022 04; 122(?):217-219. doi: 10.1016/j.jhin.2022.02.001. [PMID: 35139426]
  • Cornélie Fanton D'Andon, Patricia Correia, Josselin Rigaill, Benjamin Kably, Sophie Perinel-Ragey, Manon Launay. Ceftazidime dosing in obese patients: is it time for more?. Expert opinion on drug metabolism & toxicology. 2022 Apr; 18(4):277-284. doi: 10.1080/17425255.2022.2080052. [PMID: 35583387]
  • Gabriele Bianco, Matteo Boattini, Sara Comini, Roberto Casale, Marco Iannaccone, Rossana Cavallo, Cristina Costa. Occurrence of multi-carbapenemases producers among carbapenemase-producing Enterobacterales and in vitro activity of combinations including cefiderocol, ceftazidime-avibactam, meropenem-vaborbactam, and aztreonam in the COVID-19 era. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2022 Apr; 41(4):573-580. doi: 10.1007/s10096-022-04408-5. [PMID: 35061145]
  • Gabriele Arcari, Alessandra Oliva, Federica Sacco, Federica Maria Di Lella, Giammarco Raponi, Dario Tomolillo, Ambrogio Curtolo, Mario Venditti, Alessandra Carattoli. Interplay between Klebsiella pneumoniae producing KPC-31 and KPC-3 under treatment with high dosage meropenem: a case report. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2022 Mar; 41(3):495-500. doi: 10.1007/s10096-021-04388-y. [PMID: 34988712]
  • D Chen, L Xiao, D Hong, Y Zhao, X Hu, S Shi, F Chen. Epidemiology of resistance of carbapenemase-producing Klebsiella pneumoniae to ceftazidime-avibactam in a Chinese hospital. Journal of applied microbiology. 2022 Jan; 132(1):237-243. doi: 10.1111/jam.15166. [PMID: 34053144]
  • Yu-Hsin Tang, Po-Liang Lu, Ho-Yin Huang, Ying-Chi Lin. Clinical effectiveness of beta-lactams versus fluoroquinolones as empirical therapy in patients with diabetes mellitus hospitalized for urinary tract infections: A retrospective cohort study. PloS one. 2022; 17(3):e0266416. doi: 10.1371/journal.pone.0266416. [PMID: 35358291]
  • Mustafa Sadek, Laurent Poirel, Manuel Dominguez Pino, Fernando D'Emidio, Stefano Pomponio, Patrice Nordmann. Evaluation of SuperCAZ/AVI® Medium for Screening Ceftazidime-avibactam Resistant Gram-negative Isolates. Diagnostic microbiology and infectious disease. 2021 Dec; 101(4):115475. doi: 10.1016/j.diagmicrobio.2021.115475. [PMID: 34419742]
  • Ammar A Hasnie, Mauricio Kahn, Robert Centor. Ur-Ine Trouble: A Case of Nephrolithiasis in A Patient with End-Stage Renal Disease. The American journal of medicine. 2021 11; 134(11):e553-e554. doi: 10.1016/j.amjmed.2021.05.017. [PMID: 34197788]
  • Kun Feng, Nan Jia, Peijuan Zhu, Serubbabel Sy, Yanfei Liu, Dandan Dong, Shixing Zhu, Jiayuan Zhang, Yuwei Liu, Frederico S Martins, Hugh Gong, Zhihua Lv, Mingming Yu, Sherwin K B Sy, Yuanqi Zhu. Aztreonam/avibactam effect on pharmacodynamic indices for mutant selection of Escherichia coli and Klebsiella pneumoniae harbouring serine- and New Delhi metallo-β-lactamases. The Journal of antimicrobial chemotherapy. 2021 10; 76(11):2875-2883. doi: 10.1093/jac/dkab292. [PMID: 34383928]
  • Johanna Berkhout, Maria J Melchers, Anita C van Mil, Claudia M Lagarde, Wright W Nichols, Johan W Mouton. Evaluation of the post-antibiotic effect in vivo for the combination of a β-lactam antibiotic and a β-lactamase inhibitor: ceftazidime-avibactam in neutropenic mouse thigh and lung infections. Journal of chemotherapy (Florence, Italy). 2021 Oct; 33(6):400-408. doi: 10.1080/1120009x.2021.1892365. [PMID: 33682636]
  • Véronique Goncette, Nathalie Layios, Julie Descy, Frédéric Frippiat. Continuous infusion, therapeutic drug monitoring and outpatient parenteral antimicrobial therapy with ceftazidime/avibactam: a retrospective cohort study. Journal of global antimicrobial resistance. 2021 09; 26(?):15-19. doi: 10.1016/j.jgar.2021.04.015. [PMID: 33989847]
  • Anil R Maharaj, Huali Wu, Kanecia O Zimmerman, William J Muller, Janice E Sullivan, Catherine M T Sherwin, Julie Autmizguine, Mobeen H Rathore, Chi D Hornik, Amira Al-Uzri, Elizabeth H Payne, Daniel K Benjamin, Christoph P Hornik. Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity. Paediatric drugs. 2021 Sep; 23(5):499-513. doi: 10.1007/s40272-021-00460-4. [PMID: 34302290]
  • Punit J Shah, Thuytram Tran, Francis Emelogu, Farheen Tariq. Aztreonam, Ceftazidime/Avibactam, and Colistin Combination for the Management of Carbapenemase-Producing Klebsiella Pneumoniae Bacteremia: A Case Report. Journal of pharmacy practice. 2021 Aug; 34(4):653-657. doi: 10.1177/0897190019882262. [PMID: 31698984]
  • Shawna J Hawkins, Sherry K Cox, Kurt K Sladky. Pharmacokinetics of ceftazidime in Northern leopard frogs (Lithobates pipiens) at two different doses and administration routes. American journal of veterinary research. 2021 Jul; 82(7):560-565. doi: 10.2460/ajvr.82.7.560. [PMID: 34166088]
  • Christina D McNeal, Clare A Ryan, Londa J Berghaus, Brenton C Credille, Chih-Ping Lo, Virginia R Fajt. Plasma disposition of ceftazidime in healthy neonatal foals following intravenous and intramuscular administration. Journal of veterinary pharmacology and therapeutics. 2021 Jul; 44(4):560-567. doi: 10.1111/jvp.12947. [PMID: 33511670]
  • Joan Bergman, Lainey Harvill, Shawna Hawkins, Kurt Sladky, Sherry Cox. Determination of ceftazidime in plasma by RP-HPLC and ultraviolet detection. Biomedical chromatography : BMC. 2021 Jul; 35(7):e5104. doi: 10.1002/bmc.5104. [PMID: 33629742]
  • Marianna Meschiari, Iacopo Franconi, Erica Bacca, Vincenzo Bianco, Gabriella Orlando, Gianluca Cuomo, Andrea Bedini, Cristina Mussini. Ceftazidime/avibactam and ceftolozane/tazobactam for the treatment of extensively drug-resistant Pseudomonas aeruginosa post-neurosurgical infections: three cases and a review of the literature. Infection. 2021 Jun; 49(3):549-553. doi: 10.1007/s15010-020-01539-9. [PMID: 33074365]
  • ChangDong Lin, Yue Li, YueBin Zhang, ZhaoYuan Liu, Xia Mu, Chenjian Gu, Jing Liu, Yutang Li, GuoHui Li, JianFeng Chen. Ceftazidime is a potential drug to inhibit SARS-CoV-2 infection in vitro by blocking spike protein-ACE2 interaction. Signal transduction and targeted therapy. 2021 05; 6(1):198. doi: 10.1038/s41392-021-00619-y. [PMID: 34006835]
  • Francesco Perrotta, Marco Paolo Perrini. Successful Treatment of Klebsiella pneumoniae NDM Sepsis and Intestinal Decolonization with Ceftazidime/Avibactam Plus Aztreonam Combination in a Patient with TTP Complicated by SARSCoV-2 Nosocomial Infection. Medicina (Kaunas, Lithuania). 2021 Apr; 57(5):. doi: 10.3390/medicina57050424. [PMID: 33924769]
  • Jie Zhou, Xiang You, Meng Ke, Lingling Ye, Wanhong Wu, Pinfang Huang, Cuihong Lin. Dosage Adjustment for Ceftazidime in Pediatric Patients With Renal Impairment Using Physiologically Based Pharmacokinetic Modeling. Journal of pharmaceutical sciences. 2021 04; 110(4):1853-1862. doi: 10.1016/j.xphs.2021.02.001. [PMID: 33556385]
  • Selina Schießer, Florian Hitzenbichler, Martin G Kees, Alexander Kratzer, Matthias Lubnow, Bernd Salzberger, Frieder Kees, Christoph Dorn. Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics: An Applicability Study in Intensive Care Unit Patients. Therapeutic drug monitoring. 2021 04; 43(2):264-270. doi: 10.1097/ftd.0000000000000827. [PMID: 33086362]
  • Kari E Musgrave, Christopher S Hanley, Mark G Papich. POPULATION PHARMACOKINETICS OF CEFTAZIDIME AFTER A SINGLE SUBCUTANEOUS INJECTION AND NORMAL ORAL AND CLOACAL BACTERIAL FLORA SURVEY IN EASTERN HELLBENDERS (CRYPTOBRANCHUS ALLEGANIENSIS ALLEGANIENSIS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2021 Apr; 52(1):90-96. doi: 10.1638/2020-0145. [PMID: 33827165]
  • Raja Amarendra Muthina, Naveen Kumar Koppara, Maria Bethasaida Manuel, Alekhya Naga Bommu, Sunnesh Reddy Anapalli, Sangeetha Lakshmi Boju, Ram Rapur, Siva Kumar Vishnubotla. Cerebral abscess and calvarial osteomyelitis caused by Burkholderia pseudomallei in a renal transplant recipient. Transplant infectious disease : an official journal of the Transplantation Society. 2021 Apr; 23(2):e13530. doi: 10.1111/tid.13530. [PMID: 33248011]
  • Ying Wang, Zhichao Du, Yongdong Chen, Yugang Liu, Zhitang Yang. Meta-analysis: combination of meropenem vs ceftazidime and amikacin for empirical treatment of cancer patients with febrile neutropenia. Medicine. 2021 Feb; 100(8):e24883. doi: 10.1097/md.0000000000024883. [PMID: 33663117]
  • Jeffrey R Strich, Emily Ricotta, Sarah Warner, Yi Ling Lai, Cumhur Y Demirkale, Samuel F Hohmann, Chanu Rhee, Michael Klompas, Tara Palmore, John H Powers, John P Dekker, Jennifer Adjemian, Roland Matsouaka, Christopher W Woods, Robert L Danner, Sameer S Kadri. Pharmacoepidemiology of Ceftazidime-Avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 02; 72(4):611-621. doi: 10.1093/cid/ciaa061. [PMID: 32107536]
  • Zana Rubic, Silvija Soprek, Marko Jelic, Anita Novak, Ivana Goic-Barisic, Marina Radic, Arjana Tambic-Andrasevic, Marija Tonkic. Molecular Characterization of β-Lactam Resistance and Antimicrobial Susceptibility to Possible Therapeutic Options of AmpC-Producing Multidrug-Resistant Proteus mirabilis in a University Hospital of Split, Croatia. Microbial drug resistance (Larchmont, N.Y.). 2021 Feb; 27(2):162-169. doi: 10.1089/mdr.2020.0002. [PMID: 32429775]
  • Calvina E L Estaleva, Tomas F Zimba, John Osei Sekyere, Usha Govinden, Hafizah Y Chenia, Gunnar S Simonsen, Bjørg Haldorsen, Sabiha Y Essack, Arnfinn Sundsfjord. High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique. BMC infectious diseases. 2021 Jan; 21(1):16. doi: 10.1186/s12879-020-05696-y. [PMID: 33407206]
  • Worapong Nasomsong, Parnrada Nulsopapon, Dhitiwat Changpradub, Manat Pongchaidecha, Supanun Pungcharoenkijkul, Piraporn Juntanawiwat, Waristha Simsiriporn, Wichai Santimaleeworagun. The Potential Use of Ceftazidime-Avibactam Against Carbapenem Resistant Klebsiella pneumoniae Clinical Isolates Harboring Different Carbapenemase Types in a Thai University Hospital. Drug design, development and therapy. 2021; 15(?):3095-3104. doi: 10.2147/dddt.s321147. [PMID: 34295150]
  • Dennis Kühn, Carlos Metz, Frederik Seiler, Holger Wehrfritz, Sophie Roth, Mohammad Alqudrah, André Becker, Hendrik Bracht, Stefan Wagenpfeil, Mathias Hoffmann, Robert Bals, Ulrich Hübner, Jürgen Geisel, Philipp M Lepper, Sören L Becker. Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study. Critical care (London, England). 2020 11; 24(1):664. doi: 10.1186/s13054-020-03397-1. [PMID: 33239110]
  • Zhiqiang Wang, Ke Ma, Zhongju Chen, Zhiliang Guo, Guangyuan Zhao, Hui Guo, Lan Zhu, Gang Chen. Successful Treatment of Early Post-Transplant Bloodstream and Pulmonary Infection Caused by Carbapenem-Resistant Klebsiella pneumoniae With a Combination of Ceftazidime-Avibactam and Carbapenem: A Case Report. Transplantation proceedings. 2020 Nov; 52(9):2742-2746. doi: 10.1016/j.transproceed.2020.08.006. [PMID: 32861482]
  • Ting Li, Guang-Shing Cheng, Sudhakar N J Pipavath, Gregory A Kicska, Liangjin Liu, Paul E Kinahan, Wei Wu. The novel coronavirus disease (COVID-19) complicated by pulmonary embolism and acute respiratory distress syndrome. Journal of medical virology. 2020 10; 92(10):2205-2208. doi: 10.1002/jmv.26068. [PMID: 32470156]
  • Yesim Coskun, Serkan Atici. Successful Treatment of Pandrug-resistant Klebsiella pneumoniae Infection With Ceftazidime-avibactam in a Preterm Infant: A Case Report. The Pediatric infectious disease journal. 2020 09; 39(9):854-856. doi: 10.1097/inf.0000000000002807. [PMID: 32804464]
  • S Bui, A Facchin, P Ha, S Bouchet, S Leroux, F Nacka, M Fayon, E Jacqz-Aigrain. Population pharmacokinetics of ceftazidime in critically ill children: impact of cystic fibrosis. The Journal of antimicrobial chemotherapy. 2020 08; 75(8):2232-2239. doi: 10.1093/jac/dkaa170. [PMID: 32457995]
  • Upendo O Kibwana, Mtebe Majigo, Doreen Kamori, Joel Manyahi. High fecal carriage of extended Beta Lactamase producing Enterobacteriaceae among adult patients admitted in referral hospitals in Dar es Salaam, Tanzania. BMC infectious diseases. 2020 Jul; 20(1):557. doi: 10.1186/s12879-020-05272-4. [PMID: 32736605]
  • Martina Paldrychová, Eva Vaňková, Petra Kašparová, Eliška Sembolová, Olga Maťátková, Jan Masák, Vladimír Scholtz, Jaroslav Julák. Use of non-thermal plasma pre-treatment to enhance antibiotic action against mature Pseudomonas aeruginosa biofilms. World journal of microbiology & biotechnology. 2020 Jul; 36(8):108. doi: 10.1007/s11274-020-02891-6. [PMID: 32656596]
  • Arash Ghaffari-Rafi, Anthony C Netzel, Madeline Prat, Daniel T Miles. Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report. The American journal of case reports. 2020 Jun; 21(?):e923441. doi: 10.12659/ajcr.923441. [PMID: 32516303]
  • Ling Song, Zhiheng Yu, Yifan Xu, Xiaobei Li, Xuanlin Liu, Dongyang Liu, Tianyan Zhou. Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women. Biopharmaceutics & drug disposition. 2020 Jun; 41(6):248-267. doi: 10.1002/bdd.2243. [PMID: 32520400]
  • Romy D Zwittink, Diny van Zoeren-Grobben, Ingrid B Renes, Richard A van Lingen, Obbe F Norbruis, Rocio Martin, Liesbeth J Groot Jebbink, Jan Knol, Clara Belzer. Dynamics of the bacterial gut microbiota in preterm and term infants after intravenous amoxicillin/ceftazidime treatment. BMC pediatrics. 2020 05; 20(1):195. doi: 10.1186/s12887-020-02067-z. [PMID: 32380969]
  • Tommaso Giani, Alberto Antonelli, Samanta Sennati, Vincenzo Di Pilato, Adriana Chiarelli, Antonio Cannatelli, Christopher Gatsch, Francesco Luzzaro, Teresa Spanu, Stefania Stefani, Gian Maria Rossolini. Results of the Italian infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-IT): activity of ceftazidime/avibactam against Enterobacterales isolated from urine. The Journal of antimicrobial chemotherapy. 2020 04; 75(4):979-983. doi: 10.1093/jac/dkz547. [PMID: 31958125]
  • Vikas Gautam, Johan W Mouton, Marian T Ten Kate, Irma A J M Bakker-Woudenberg, Sebastian van Burgh, Nikolaos Strepis, Corné H W Klaassen, Wil Goessens. Cefpirome Treatment Results in Limited Selection of Stable Derepressed Enterobacter cloacae Mutants in the Intestinal Flora of Rats Treated for an Experimental Klebsiella pneumoniae Pulmonary Infection. Microbial drug resistance (Larchmont, N.Y.). 2020 Apr; 26(4):341-348. doi: 10.1089/mdr.2018.0473. [PMID: 31657651]
  • Pan Gao, Zonglai Liu, Han Yang, Ziqiu He, Zhi Zhang, Xiong Guo, Hongbo Zhang, Wei Ai, Dan Du. Ceftazidime-related urinary calculi in a young boy: a case report. The Journal of international medical research. 2020 Apr; 48(4):300060520921667. doi: 10.1177/0300060520921667. [PMID: 32351152]
  • Marco Coppi, Vincenzo Di Pilato, Francesco Monaco, Tommaso Giani, Pier Giulio Conaldi, Gian Maria Rossolini. Ceftazidime-Avibactam Resistance Associated with Increased bla KPC-3 Gene Copy Number Mediated by pKpQIL Plasmid Derivatives in Sequence Type 258 Klebsiella pneumoniae. Antimicrobial agents and chemotherapy. 2020 03; 64(4):. doi: 10.1128/aac.01816-19. [PMID: 31964792]
  • Ruta Petraitiene, Vidmantas Petraitis, Povilas Kavaliauskas, Bo Bo W Maung, Farehin Khan, Ethan Naing, Thein Aung, Vilma Zigmantaite, Ramune Grigaleviciute, Audrius Kucinskas, Rimantas Stakauskas, Benjamin N Georgiades, Chase A Mazur, Joshua A Hayden, Michael J Satlin, Thomas J Walsh. Pharmacokinetics and Efficacy of Ceftazidime-Avibactam in the Treatment of Experimental Pneumonia Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae in Persistently Neutropenic Rabbits. Antimicrobial agents and chemotherapy. 2020 03; 64(4):. doi: 10.1128/aac.02157-19. [PMID: 32015048]
  • L Zhao, X Li, X He, L Jian. Levofloxacin-ceftazidime administration regimens combat Pseudomonas aeruginosa in the hollow-fiber infection model simulating abnormal renal function in critically ill patients. BMC pharmacology & toxicology. 2020 03; 21(1):20. doi: 10.1186/s40360-020-0396-5. [PMID: 32131897]
  • Shampa Das, Diansong Zhou, Wright W Nichols, Andy Townsend, Paul Newell, Jianguo Li. Selecting the dosage of ceftazidime-avibactam in the perfect storm of nosocomial pneumonia. European journal of clinical pharmacology. 2020 Mar; 76(3):349-361. doi: 10.1007/s00228-019-02804-z. [PMID: 31836928]
  • Hasan Cenk Mirza, Elvan Hortaç, Aylin Altay Koçak, M Hamiyet Demirkaya, Buket Yayla, Aylin Üsküdar Güçlü, Ahmet Başustaoğlu. In vitro activity of ceftolozane-tazobactam and ceftazidime-avibactam against clinical isolates of meropenem-non-susceptible Pseudomonas aeruginosa: A two-centre study. Journal of global antimicrobial resistance. 2020 03; 20(?):334-338. doi: 10.1016/j.jgar.2019.09.016. [PMID: 31568882]
  • Pinpongsarn Triyawatanyu, Pajaree Chariyavilaskul, Weeraya Phaisal, Sadudee Peerapornratana, Talerngsak Kanjanabuch, Kearkiat Praditpornsilpa, Pisut Katavetin. Intraperitoneal cefazolin and ceftazidime during short-dwell exchange in peritoneal dialysis patients with peritonitis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2020 03; 40(2):179-184. doi: 10.1177/0896860819893820. [PMID: 32063189]
  • Paige Soukup, Andrew C Faust, Vindhya Edpuganti, William C Putnam, James A McKinnell. Steady-State Ceftazidime-Avibactam Serum Concentrations and Dosing Recommendations in a Critically Ill Patient Being Treated for Pseudomonas aeruginosa Pneumonia and Undergoing Continuous Venovenous Hemodiafiltration. Pharmacotherapy. 2019 12; 39(12):1216-1222. doi: 10.1002/phar.2338. [PMID: 31596506]
  • Ashley Ferro, Meryl Griffiths, Rona Smith, Andrew Fry. Acute kidney injury as the presenting complaint of ceftazidime-induced immune-mediated haemolysis. BMJ case reports. 2019 Nov; 12(11):. doi: 10.1136/bcr-2019-232884. [PMID: 31732539]
  • Thidarat Kitrungphaiboon, Pongpratch Puapatanakul, Piyatida Chuengsaman, Krittaya Tiskajornsiri, Guttiga Halue, Monchai Siribamrungwong, Saraporn Matayart, Kamonrat Chongthanakorn, Ussanee Poonvivatchaikarn, Chanchana Boonyakrai, Wanida Somboonsilp, Pisut Katavetin, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, David W Johnson, Talerngsak Kanjanabuch. Intraperitoneal Cefepime Monotherapy Versus Combination Therapy of Cefazolin Plus Ceftazidime for Empirical Treatment of CAPD-Associated Peritonitis: A Multicenter, Open-Label, Noninferiority, Randomized, Controlled Trial. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2019 11; 74(5):601-609. doi: 10.1053/j.ajkd.2019.05.011. [PMID: 31331757]
  • Muthana Al Sahlawi, Adrian Liew, Jeffrey Perl. Cefepime as Empirical Peritoneal Dialysis-Associated Peritonitis Treatment: Something to Dwell On?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2019 11; 74(5):579-582. doi: 10.1053/j.ajkd.2019.06.008. [PMID: 31515138]
  • Carolina Saffioti, Sebastiano Barco, Giuliana Cangemi, Alessio Mesini, Rosaria Casciaro, Federico Cresta, Carlo Castellani, Roberto Bandettini, Patrizia Morelli, Elio Castagnola. Ceftazidime plasma concentration in a patient with cystic fibrosis treated with ceftazidime/avibactam plus trimethoprim/sulfametoxazole for Bulkholderia cepacia reacutization. Journal of chemotherapy (Florence, Italy). 2019 Nov; 31(7-8):436-438. doi: 10.1080/1120009x.2019.1671654. [PMID: 31583970]
  • Paul B Eckburg, Troy Lister, Susannah Walpole, Tim Keutzer, Luke Utley, John Tomayko, Ellen Kopp, Nicholas Farinola, Scott Coleman. Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β-Lactam Antibiotics in Healthy Subjects. Antimicrobial agents and chemotherapy. 2019 09; 63(9):. doi: 10.1128/aac.00892-19. [PMID: 31262767]
  • Temilolu Idowu, Derek Ammeter, Gilbert Arthur, George G Zhanel, Frank Schweizer. Potentiation of β-lactam antibiotics and β-lactam/β-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin-cyclam conjugates. The Journal of antimicrobial chemotherapy. 2019 09; 74(9):2640-2648. doi: 10.1093/jac/dkz228. [PMID: 31139830]
  • Janni S Mortensen, Berit P Jensen, Mei Zhang, Matthew Doogue. Preanalytical Stability of Piperacillin, Tazobactam, Meropenem, and Ceftazidime in Plasma and Whole Blood Using Liquid Chromatography-Tandem Mass Spectrometry. Therapeutic drug monitoring. 2019 08; 41(4):538-543. doi: 10.1097/ftd.0000000000000650. [PMID: 31306394]
  • Li Zhou, Xiao Tong, Pradeep Sharma, Hongmei Xu, Nidal Al-Huniti, Diansong Zhou. Physiologically based pharmacokinetic modelling to predict exposure differences in healthy volunteers and subjects with renal impairment: Ceftazidime case study. Basic & clinical pharmacology & toxicology. 2019 Aug; 125(2):100-107. doi: 10.1111/bcpt.13209. [PMID: 30739396]
  • Valentina Viaggi, Beatrice Pini, Silvia Tonolo, Francesco Luzzaro, Luigi Principe. In vitro activity of ceftazidime/avibactam against clinical isolates of ESBL-producing Enterobacteriaceae in Italy. Journal of chemotherapy (Florence, Italy). 2019 Jul; 31(4):195-201. doi: 10.1080/1120009x.2019.1620406. [PMID: 31130090]
  • Valeria Daccò, Laura Claut, Stefania Piconi, Luca Castellazzi, Francesca Garbarino, Antonio Teri, Carla Colombo. Successful ceftazidime-avibactam treatment of post-surgery Burkholderia multivorans genomovar II bacteremia and brain abscesses in a young lung transplanted woman with cystic fibrosis. Transplant infectious disease : an official journal of the Transplantation Society. 2019 Jun; 21(3):e13082. doi: 10.1111/tid.13082. [PMID: 30892778]
  • Jamie L Miller, Peter N Johnson, Bryan P White, Stephen B Neely, Hala Chaaban, Netsanet Kassa, Robert C Welliver. Impact of Ceftazidime Use on Susceptibility Patterns in the Neonatal Intensive Care Unit. The Pediatric infectious disease journal. 2019 06; 38(6):605-607. doi: 10.1097/inf.0000000000002255. [PMID: 30489466]
  • Pier Giorgio Cojutti, Natalia Maximova, Giulia Schillani, William Hope, Federico Pea. Population pharmacokinetics of continuous-infusion ceftazidime in febrile neutropenic children undergoing HSCT: implications for target attainment for empirical treatment against Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy. 2019 06; 74(6):1648-1655. doi: 10.1093/jac/dkz065. [PMID: 30838391]
  • G Spoletini, C Etherington, N Shaw, I J Clifton, M Denton, P Whitaker, D G Peckham. Use of ceftazidime/avibactam for the treatment of MDR Pseudomonas aeruginosa and Burkholderia cepacia complex infections in cystic fibrosis: a case series. The Journal of antimicrobial chemotherapy. 2019 05; 74(5):1425-1429. doi: 10.1093/jac/dky558. [PMID: 30649419]
  • Poonam Giri, Harilal Patel, Nuggehally R Srinivas. Review of Clinical Pharmacokinetics of Avibactam, A Newly Approved non-β lactam β-lactamase Inhibitor Drug, In Combination Use With Ceftazidime. Drug research. 2019 May; 69(5):245-255. doi: 10.1055/a-0748-5548. [PMID: 30296806]
  • Nicola Peruzzu, Silvio Borrelli, Antonella Netti, Toni De Stefano, Carlo Vita, Maria Sabatino, Michela Salzano, Giuseppe Conte, Luca De Nicola, Roberto Minutolo, Carlo Garofalo. [Infected hepatic cyst in ADPKD patient in peritoneal dialysis]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 2019 Apr; 36(2):. doi: NULL. [PMID: 30983178]
  • Jianguo Li, Mark Lovern, Michelle L Green, Joannellyn Chiu, Diansong Zhou, Craig Comisar, Yuan Xiong, Jeremy Hing, Merran MacPherson, James G Wright, Todd Riccobene, Timothy J Carrothers, Shampa Das. Ceftazidime-Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups. Clinical and translational science. 2019 03; 12(2):151-163. doi: 10.1111/cts.12585. [PMID: 30221827]
  • Bela Kocsis, Akos Toth, Daniel Gulyas, Balazs Ligeti, Katalin Katona, Laszlo Rokusz, Dora Szabo. Acquired qnrVC1 and blaNDM-1 resistance markers in an international high-risk Pseudomonas aeruginosa ST773 clone. Journal of medical microbiology. 2019 Mar; 68(3):336-338. doi: 10.1099/jmm.0.000927. [PMID: 30667355]
  • George G Zhanel, Alyssa R Golden, Sheryl Zelenitsky, Karyn Wiebe, Courtney K Lawrence, Heather J Adam, Temilolu Idowu, Ronald Domalaon, Frank Schweizer, Michael A Zhanel, Philippe R S Lagacé-Wiens, Andrew J Walkty, Ayman Noreddin, Joseph P Lynch Iii, James A Karlowsky. Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli. Drugs. 2019 Feb; 79(3):271-289. doi: 10.1007/s40265-019-1055-2. [PMID: 30712199]
  • Jason M Pogue, Robert A Bonomo, Keith S Kaye. Ceftazidime/Avibactam, Meropenem/Vaborbactam, or Both? Clinical and Formulary Considerations. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2019 01; 68(3):519-524. doi: 10.1093/cid/ciy576. [PMID: 30020449]
  • Dejenie Shiferaw Teklu, Abebe Aseffa Negeri, Melese Hailu Legese, Tesfaye Legesse Bedada, Hiwot Ketema Woldemariam, Kassu Desta Tullu. Extended-spectrum beta-lactamase production and multi-drug resistance among Enterobacteriaceae isolated in Addis Ababa, Ethiopia. Antimicrobial resistance and infection control. 2019; 8(?):39. doi: 10.1186/s13756-019-0488-4. [PMID: 30815254]
  • Gary E Stein, Curtis L Smith, Amy Scharmen, James M Kidd, Christopher Cooper, Joseph Kuti, Subhashis Mitra, David P Nicolau, Daniel H Havlichek. Pharmacokinetic and Pharmacodynamic Analysis of Ceftazidime/Avibactam in Critically Ill Patients. Surgical infections. 2019 Jan; 20(1):55-61. doi: 10.1089/sur.2018.141. [PMID: 30351195]
  • Tiago J Carvalho, Patrícia Quadros Branco, Ana Rita Martins, Augusta Gaspar. Chryseobacterium indologenes peritonitis in a peritoneal dialysis patient. BMJ case reports. 2018 Dec; 11(1):. doi: 10.1136/bcr-2018-227713. [PMID: 30567209]
  • Monique R Bidell, Thomas P Lodise. Suboptimal Clinical Response Rates with Newer Antibiotics Among Patients with Moderate Renal Impairment: Review of the Literature and Potential Pharmacokinetic and Pharmacodynamic Considerations for Observed Findings. Pharmacotherapy. 2018 12; 38(12):1205-1215. doi: 10.1002/phar.2184. [PMID: 30289995]
  • Richard Dimelow, James G Wright, Merran MacPherson, Paul Newell, Shampa Das. Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers. Drugs in R&D. 2018 Sep; 18(3):221-230. doi: 10.1007/s40268-018-0241-0. [PMID: 30054895]
  • A J Cerreta, G A Lewbart, D R Dise, M G Papich. Population pharmacokinetics of ceftazidime after a single intramuscular injection in wild turtles. Journal of veterinary pharmacology and therapeutics. 2018 Aug; 41(4):495-501. doi: 10.1111/jvp.12500. [PMID: 29517112]
  • Honghong Wang, Xingang Li, Shusen Sun, Guifu Mao, Ping Xiao, Chan Fu, Zhuoxin Liang, Min Zheng, Yuling Huang, Haihong Tang, Renhao Ou, Ni Yang, Xi Ling, Zhigang Zhao. Population Pharmacokinetics and Dosing Simulations of Ceftazidime in Chinese Neonates. Journal of pharmaceutical sciences. 2018 05; 107(5):1416-1422. doi: 10.1016/j.xphs.2017.12.018. [PMID: 29274818]
  • Eris Cani, Farzad Moussavi, Eric Ocheretyaner, Roopali Sharma, Clinton Brown, Brandon Eilertson. Carbapenem-resistant Klebsiella pneumoniae vertebral osteomyelitis in a renal transplant recipient treated with ceftazidime-avibactam. Transplant infectious disease : an official journal of the Transplantation Society. 2018 Apr; 20(2):e12837. doi: 10.1111/tid.12837. [PMID: 29359842]
  • María García-Castillo, Sergio García-Fernández, Rosa Gómez-Gil, Cristina Pitart, Marina Oviaño, Irene Gracia-Ahufinger, Jazmín Díaz-Regañón, Marta Tato, Rafael Cantón. Activity of ceftazidime-avibactam against carbapenemase-producing Enterobacteriaceae from urine specimens obtained during the infection-carbapenem resistance evaluation surveillance trial (iCREST) in Spain. International journal of antimicrobial agents. 2018 Mar; 51(3):511-515. doi: 10.1016/j.ijantimicag.2018.01.011. [PMID: 29371104]
  • Marco Falcone, Pierluigi Viale, Giusy Tiseo, Manjunath Pai. Pharmacokinetic drug evaluation of avibactam + ceftazidime for the treatment of hospital-acquired pneumonia. Expert opinion on drug metabolism & toxicology. 2018 Mar; 14(3):331-340. doi: 10.1080/17425255.2018.1434142. [PMID: 29373935]
  • Bülent Şengül, Şükrü Beydemir. The interactions of cephalosporins on polyol pathway enzymes from sheep kidney. Archives of physiology and biochemistry. 2018 Feb; 124(1):35-44. doi: 10.1080/13813455.2017.1358749. [PMID: 28758816]
  • Wanhong Lu, Bonnie Ching-Ha Kwan, Kai Ming Chow, Wing-Fai Pang, Chi Bon Leung, Philip Kam-To Li, Cheuk Chun Szeto. Peritoneal dialysis-related peritonitis caused by Pseudomonas species: Insight from a post-millennial case series. PloS one. 2018; 13(5):e0196499. doi: 10.1371/journal.pone.0196499. [PMID: 29746497]
  • Mohammad Khursheed Siddiqi, Parvez Alam, Sumit Kumar Chaturvedi, Saima Nusrat, Mohammad Rehan Ajmal, Ali Saber Abdelhameed, Rizwan Hasan Khan. Probing the interaction of cephalosporin antibiotic-ceftazidime with human serum albumin: A biophysical investigation. International journal of biological macromolecules. 2017 Dec; 105(Pt 1):292-299. doi: 10.1016/j.ijbiomac.2017.07.036. [PMID: 28693993]
  • Nadine Pinder, Thorsten Brenner, Stefanie Swoboda, Markus A Weigand, Torsten Hoppe-Tichy. Therapeutic drug monitoring of beta-lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-UV. Journal of pharmaceutical and biomedical analysis. 2017 Sep; 143(?):86-93. doi: 10.1016/j.jpba.2017.05.037. [PMID: 28578254]
  • Uraib Sharaha, Eladio Rodriguez-Diaz, Klaris Riesenberg, Irving J Bigio, Mahmoud Huleihel, Ahmad Salman. Using Infrared Spectroscopy and Multivariate Analysis to Detect Antibiotics' Resistant Escherichia coli Bacteria. Analytical chemistry. 2017 09; 89(17):8782-8790. doi: 10.1021/acs.analchem.7b01025. [PMID: 28731324]
  • Ruud R G Bueters, Annelies Jeronimus-Klaasen, Roger J M Brüggemann, Lambertus P van den Heuvel, Michiel F Schreuder. Early postnatal gentamicin and ceftazidime treatment in normal and food restricted neonatal wistar rats: Implications for kidney development. Birth defects research. 2017 Sep; 109(15):1228-1235. doi: 10.1002/bdr2.1071. [PMID: 28696058]
  • R Y Tang, B M Cheong. Multiple bilateral renal abscesses in a previously healthy young patient. The Medical journal of Malaysia. 2017 08; 72(4):250-251. doi: NULL. [PMID: 28889140]
  • Eric Wenzler, Kristen L Bunnell, Susan C Bleasdale, Scott Benken, Larry H Danziger, Keith A Rodvold. Pharmacokinetics and Dialytic Clearance of Ceftazidime-Avibactam in a Critically Ill Patient on Continuous Venovenous Hemofiltration. Antimicrobial agents and chemotherapy. 2017 07; 61(7):. doi: 10.1128/aac.00464-17. [PMID: 28416553]
  • Alexander R Shaw, Bruce A Mueller. Antibiotic Dosing in Continuous Renal Replacement Therapy. Advances in chronic kidney disease. 2017 07; 24(4):219-227. doi: 10.1053/j.ackd.2017.05.004. [PMID: 28778361]
  • Rong Xu, Zhikai Yang, Zhen Qu, Huan Wang, Xue Tian, David W Johnson, Jie Dong. Intraperitoneal Vancomycin Plus Either Oral Moxifloxacin or Intraperitoneal Ceftazidime for the Treatment of Peritoneal Dialysis-Related Peritonitis: A Randomized Controlled Pilot Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2017 Jul; 70(1):30-37. doi: 10.1053/j.ajkd.2016.11.008. [PMID: 28027794]
  • Sadudee Peerapornratana, Pajaree Chariyavilaskul, Talerngsak Kanjanabuch, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Pisut Katavetin. Short-Dwell Cycling Intraperitoneal Cefazolin Plus Ceftazidime in Peritoneal Dialysis Patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2017 Mar; 37(2):218-224. doi: 10.3747/pdi.2015.00300. [PMID: 27738089]
  • Aleksandra Hernik, Ewelina Szczepanek-Parulska, Bogusz Falkowski, Hanna Komarowska, Michał Drews, Marek Ruchała. A diabetic patient with suppurative thyroiditis due to Salmonella enterica complicated by acute kidney injury. Polish archives of internal medicine. 2017 02; 127(2):131-132. doi: 10.20452/pamw.3957. [PMID: 28267139]
  • Henri Merdjan, Antoine Tarral, Shampa Das, Jianguo Li. Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients With Renal Impairment. Journal of clinical pharmacology. 2017 02; 57(2):211-218. doi: 10.1002/jcph.793. [PMID: 27402250]
  • Esther Ríos, María Carmen López, Iciar Rodríguez-Avial, Esther Culebras, Juan José Picazo. Detection of Escherichia coli ST131 clonal complex (ST705) and Klebsiella pneumoniae ST15 among faecal carriage of extended-spectrum β-lactamase- and carbapenemase-producing Enterobacteriaceae. Journal of medical microbiology. 2017 Feb; 66(2):169-174. doi: 10.1099/jmm.0.000399. [PMID: 27902381]
  • Goran Hauser, Ivana Blažević, Nermin Salkić, Goran Poropat, Vanja Giljača, Zlatko Bulić, Davor Štimac. Diclofenac sodium versus ceftazidime for preventing pancreatitis after endoscopic retrograde cholangiopancreatography: a prospective, randomized, controlled trial. Surgical endoscopy. 2017 02; 31(2):602-610. doi: 10.1007/s00464-016-5004-9. [PMID: 27317032]