(+)-Pyridinoline (BioDeep_00000925253)
代谢物信息卡片
(+)-Pyridinoline
化学式: C18H29N4O8+ (429.1985294)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C(=C(C=[N+]1CC(CCC(C(=O)O)N)O)O)CC(C(=O)O)N)CCC(C(=O)O)N
InChI: InChI=1S/C18H28N4O8/c19-12(16(25)26)3-1-9-6-22(7-10(23)2-4-13(20)17(27)28)8-15(24)11(9)5-14(21)18(29)30/h6,8,10,12-14,23H,1-5,7,19-21H2,(H3-,24,25,26,27,28,29,30)/p+1/t10-,12+,13+,14+/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Qiang Li, Lansheng Hu, Zhijun Zhao, Li Ma, Jiquan Li, Liqing Xu, Jiming Wang. Serum changes in pyridinoline, type II collagen cleavage neoepitope and osteocalcin in early stage male brucellosis patients.
Scientific reports.
2020 10; 10(1):17190. doi:
10.1038/s41598-020-72565-8. [PMID: 33057028] - Abby Pritchard, Cara Robison, Tristin Nguyen, Brian D Nielsen. Silicon supplementation affects mineral metabolism but not bone density or strength in male broilers.
PloS one.
2020; 15(12):e0243007. doi:
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Journal of orthopaedic surgery and research.
2019 Oct; 14(1):328. doi:
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Planta medica.
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Journal of separation science.
2019 Apr; 42(8):1482-1488. doi:
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2019 Jan; 14(1):17. doi:
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Aviation, space, and environmental medicine.
2009 Feb; 80(2):88-93. doi:
10.3357/asem.2368.2009. [PMID: 19198193] - Jun Hashimoto, Patrick Garnero, Désirée van der Heijde, Nobuyuki Miyasaka, Kazuhiko Yamamoto, Shinichi Kawai, Tsutomu Takeuchi, Hideki Yoshikawa, Norihiro Nishimoto. A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs.
Modern rheumatology.
2009; 19(3):273-82. doi:
10.1007/s10165-009-0170-4. [PMID: 19452245] - Ruy Carrasco, Daniel J Lovell, Edward H Giannini, Carol J Henderson, Bin Huang, Sandy Kramer, Julie Ranz, James Heubi, David Glass. Biochemical markers of bone turnover associated with calcium supplementation in children with juvenile rheumatoid arthritis: results of a double-blind, placebo-controlled intervention trial.
Arthritis and rheumatism.
2008 Dec; 58(12):3932-40. doi:
10.1002/art.24041. [PMID: 19035501] - D A Martinez, P E Patterson-Buckendahl, A Lust, K M Shea-Rangel, T M Hoban-Higgins, C A Fuller, A C Vailas. A noninvasive analysis of urinary musculoskeletal collagen metabolism markers from rhesus monkeys subject to chronic hypergravity.
Journal of applied physiology (Bethesda, Md. : 1985).
2008 Oct; 105(4):1255-61. doi:
10.1152/japplphysiol.00573.2007. [PMID: 18653754] - Kageyama Yasunori, Takahashi Masaaki, Nagafusa Tetsuyuki, Kobayashi Hayato, Nagano Akira. Reduction of urinary levels of pyridinoline and deoxypyridinoline and serum levels of soluble receptor activator of NF-kappaB ligand by etanercept in patients with rheumatoid arthritis.
Clinical rheumatology.
2008 Sep; 27(9):1093-101. doi:
10.1007/s10067-008-0870-8. [PMID: 18338203] - C Heiss, L M Hoesel, M Pausch, S A Meissner, U Horas, O Kilian, U Wehr, W A Rambeck, R Schnettler. [Biochemical bone resorption markers during the healing of osteoporotic fractures].
Der Unfallchirurg.
2008 Sep; 111(9):695-702. doi:
10.1007/s00113-008-1465-1. [PMID: 18618089] - Hiroshi Ohshima, Chiaki Mukai. [Bone metabolism in human space flight and bed rest study].
Clinical calcium.
2008 Sep; 18(9):1245-53. doi:
clica080912451253. [PMID: 18758029] - Virginia Gargano, Mariangela Massaro, Ilaria Morra, Carmen Formisano, Costantino Di Carlo, Carmine Nappi. Effects of two low-dose combined oral contraceptives containing drospirenone on bone turnover and bone mineral density in young fertile women: a prospective controlled randomized study.
Contraception.
2008 Jul; 78(1):10-5. doi:
10.1016/j.contraception.2008.01.016. [PMID: 18555812] - Rikke Andersen, Christian Mølgaard, Lene T Skovgaard, Christine Brot, Kevin D Cashman, Jette Jakobsen, Christel Lamberg-Allardt, Lars Ovesen. Effect of vitamin D supplementation on bone and vitamin D status among Pakistani immigrants in Denmark: a randomised double-blinded placebo-controlled intervention study.
The British journal of nutrition.
2008 Jul; 100(1):197-207. doi:
10.1017/s000711450789430x. [PMID: 18208636] - Cecilia Giunta, Nursel H Elçioglu, Beate Albrecht, Georg Eich, Céline Chambaz, Andreas R Janecke, Heather Yeowell, MaryAnn Weis, David R Eyre, Marius Kraenzlin, Beat Steinmann. Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13.
American journal of human genetics.
2008 Jun; 82(6):1290-305. doi:
10.1016/j.ajhg.2008.05.001. [PMID: 18513683] - Rudolph Schutte, Tim S Nawrot, Tom Richart, Lutgarde Thijs, Dirk Vanderschueren, Tatiana Kuznetsova, Etienne Van Hecke, Harry A Roels, Jan A Staessen. Bone resorption and environmental exposure to cadmium in women: a population study.
Environmental health perspectives.
2008 Jun; 116(6):777-83. doi:
10.1289/ehp.11167. [PMID: 18560534] - David A Stevenson, Elisabeth L Schwarz, David H Viskochil, Laurie J Moyer-Mileur, Mary Murray, Sean D Firth, Jacques L D'Astous, John C Carey, Marzia Pasquali. Evidence of increased bone resorption in neurofibromatosis type 1 using urinary pyridinium crosslink analysis.
Pediatric research.
2008 Jun; 63(6):697-701. doi:
10.1203/pdr.0b013e31816fee45. [PMID: 18317233] - Helen M Macdonald, Fiona E McGuigan, Susan A Lanham-New, William D Fraser, Stuart H Ralston, David M Reid. Vitamin K1 intake is associated with higher bone mineral density and reduced bone resorption in early postmenopausal Scottish women: no evidence of gene-nutrient interaction with apolipoprotein E polymorphisms.
The American journal of clinical nutrition.
2008 May; 87(5):1513-20. doi:
10.1093/ajcn/87.5.1513. [PMID: 18469278] - D Wernicke, A Voigt, A Müller, W A Schmidt, P Stiehl, G Hein. [Association between histopathologic type II synovitis and increased amounts of pyridinoline in synovial tissue samples in rheumatoid arthritis].
Zeitschrift fur Rheumatologie.
2008 May; 67(3):225-31. doi:
10.1007/s00393-008-0292-7. [PMID: 18369645] - Shailendra Kapoor. TGF-beta 1 and urinary excretion of pyridinium crosslinks: Two often overlooked risk factors for assessing risk of progression in patients with monoclonal gammopathy of undetermined significance.
Haematologica.
2008 Mar; 93(3):e38. doi:
10.3324/haematol.12760. [PMID: 18310534] - Kosei Hasegawa, Kyoko Kataoka, Masaru Inoue, Yoshiki Seino, Tsuneo Morishima, Hiroyuki Tanaka. Impaired pyridinoline cross-link formation in patients with osteogenesis imperfecta.
Journal of bone and mineral metabolism.
2008; 26(4):394-9. doi:
10.1007/s00774-007-0827-z. [PMID: 18600407] - Andreas Müller, C Bölzner, T Eidner, U C Smolenski, G E Hein. Factors modifying collagen catabolism in patients with ankylosing spondylitis.
European journal of medical research.
2007 Nov; 12(11):568-72. doi:
NULL. [PMID: 18024266] - Daniel Arens, Ilonka Sigrist, Mauro Alini, Peter Schawalder, Erich Schneider, Marcus Egermann. Seasonal changes in bone metabolism in sheep.
Veterinary journal (London, England : 1997).
2007 Nov; 174(3):585-91. doi:
10.1016/j.tvjl.2006.10.001. [PMID: 17141541] - Steven Young-Min, Tim Cawston, Nicola Marshall, David Coady, Stephan Christgau, Tore Saxne, Simon Robins, Ian Griffiths. Biomarkers predict radiographic progression in early rheumatoid arthritis and perform well compared with traditional markers.
Arthritis and rheumatism.
2007 Oct; 56(10):3236-47. doi:
10.1002/art.22923. [PMID: 17907159] - Graeme Jones, Terry Dwyer, Kristen L Hynes, Venkat Parameswaran, Ray Udayan, Timothy M Greenaway. A prospective study of urinary electrolytes and bone turnover in adolescent males.
Clinical nutrition (Edinburgh, Scotland).
2007 Oct; 26(5):619-23. doi:
10.1016/j.clnu.2007.06.014. [PMID: 17904253] - Selahattin Kumru, Azer A Yildiz, Bayram Yilmaz, Suleyman Sandal, Bilgin Gurates. Effects of aromatase inhibitors letrozole and anastrazole on bone metabolism and steroid hormone levels in intact female rats.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2007 Oct; 23(10):556-61. doi:
10.1080/09513590701557119. [PMID: 17952760] - Tom R Hill, David McCarthy, Jette Jakobsen, Christel Lamberg-Allardt, Mairead Kiely, Kevin D Cashman. Seasonal changes in vitamin D status and bone turnover in healthy Irish postmenopausal women.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2007 Sep; 77(5):320-5. doi:
10.1024/0300-9831.77.5.320. [PMID: 18453316] - Andreas Ludwig Reiter, Andreas Volk, Jens Vollmar, Bernd Fromm, Hans Juergen Gerner. Changes of basic bone turnover parameters in short-term and long-term patients with spinal cord injury.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society.
2007 Jun; 16(6):771-6. doi:
10.1007/s00586-006-0163-3. [PMID: 16830131] - I N G Springer, J Wiltfang, A Dunsche, G C Lier, M Bartsch, P H Warnke, E L Barth, H Terheyden, Paul A J Russo, N Czech, Y Acil. A new method of monitoring osteomyelitis.
International journal of oral and maxillofacial surgery.
2007 Jun; 36(6):527-32. doi:
10.1016/j.ijom.2007.01.001. [PMID: 17418531] - Jun Iwamoto, Tsuyoshi Takeda, Yoshihiro Sato, James K Yeh. Additive effect of vitamin K2 and risedronate on long bone mass in hypophysectomized young rats.
Experimental animals.
2007 Apr; 56(2):103-10. doi:
10.1538/expanim.56.103. [PMID: 17460355] - Robert J A Frost, Carolin Sonne, Uli Wehr, Hans-Ulrich Stempfle. Effects of calcium supplementation on bone loss and fractures in congestive heart failure.
European journal of endocrinology.
2007 Mar; 156(3):309-14. doi:
10.1530/eje-06-0614. [PMID: 17322490] - Hatice Altundal, Hakan Sayrak, Ertuğrul Yurtsever, Kamil Göker. Inhibitory effect of alendronate on bone resorption of autogenous free bone grafts in rats.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
2007 Mar; 65(3):508-16. doi:
10.1016/j.joms.2005.11.054. [PMID: 17307600] - V Camozzi, A Tossi, E Simoni, F Pagani, C M Francucci, L Moro. Role of biochemical markers of bone remodeling in clinical practice.
Journal of endocrinological investigation.
2007; 30(6 Suppl):13-7. doi:
NULL. [PMID: 17721068] - Chwan-Li Shen, James S Williams, Ming-Chien Chyu, Robert L Paige, Allen L Stephens, Katherine B Chauncey, Fiona R Prabhu, Lee T Ferris, James K Yeh. Comparison of the effects of Tai Chi and resistance training on bone metabolism in the elderly: a feasibility study.
The American journal of Chinese medicine.
2007; 35(3):369-81. doi:
10.1142/s0192415x07004898. [PMID: 17597496] - Sun Hee Do, Sung-Yong Hwa, Won-Il Jeong, Ji-Won Lee, Hyun-Jung Kim, In-Seon Lee, Kyu-Shik Jeong. ENA Actimineral Resource A restores bone loss and bone quality in ovariectomized rats.
Molecular and cellular biochemistry.
2007 Jan; 295(1-2):35-43. doi:
10.1007/s11010-006-9269-5. [PMID: 16838105] - Satyawan B Jadhav, P S Narayana Murthy, M M Singh, G K Jain. Distribution of lovastatin to bone and its effect on bone turnover in rats.
The Journal of pharmacy and pharmacology.
2006 Nov; 58(11):1451-8. doi:
10.1211/jpp.58.11.0005. [PMID: 17132207] - Fusako Teramoto, Kazuhito Rokutan, Yasuko Sugano, Kazuyuki Oku, Eriko Kishino, Koki Fujita, Kozo Hara, Kyouichi Kishi, Masao Fukunaga, Tetsuro Morita. Long-term administration of 4G-beta-D-galactosylsucrose (lactosucrose) enhances intestinal calcium absorption in young women: a randomized, placebo-controlled 96-wk study.
Journal of nutritional science and vitaminology.
2006 Oct; 52(5):337-46. doi:
10.3177/jnsv.52.337. [PMID: 17190104] - Peter Oelzner, Gabriele Lehmann, Thorsten Eidner, Sybille Franke, Andreas Müller, Gunter Wolf, Gert Hein. Hypercalcemia in rheumatoid arthritis: relationship with disease activity and bone metabolism.
Rheumatology international.
2006 Aug; 26(10):908-15. doi:
10.1007/s00296-005-0095-y. [PMID: 16404562] - Pavel Spacek, Milan Adam. Pentosidine in osteoarthritis: HPLC determination in body fluids and in tissues.
Rheumatology international.
2006 Aug; 26(10):923-7. doi:
10.1007/s00296-006-0105-8. [PMID: 16575610] - Heli T Viljakainen, Anette Palssa, Merja Kärkkäinen, Jette Jakobsen, Kevin D Cashman, Christian Mølgaard, Christel Lamberg-Allardt. A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls - a cross-sectional study.
The British journal of nutrition.
2006 Jul; 96(1):124-30. doi:
10.1079/bjn20061719. [PMID: 16870000] - D T Shaw, D W Rozeboom, G M Hill, M W Orth, D S Rosenstein, J E Link. Impact of supplement withdrawal and wheat middling inclusion on bone metabolism, bone strength, and the incidence of bone fractures occurring at slaughter in pigs.
Journal of animal science.
2006 May; 84(5):1138-46. doi:
10.2527/2006.8451138x. [PMID: 16612016] - Patrizia Tosi, Elena Zamagni, Claudia Cellini, Raffaele Parente, Delia Cangini, Paola Tacchetti, Giulia Perrone, Michela Ceccolini, Paola Boni, Sante Tura, Michele Baccarani, Michele Cavo. First-line therapy with thalidomide, dexamethasone and zoledronic acid decreases bone resorption markers in patients with multiple myeloma.
European journal of haematology.
2006 May; 76(5):399-404. doi:
10.1111/j.0902-4441.2005.t01-1-ejh2520.x. [PMID: 16480429] - Bruce A Watkins, Yong Li, Mark F Seifert. Dietary ratio of n-6/n-3 PUFAs and docosahexaenoic acid: actions on bone mineral and serum biomarkers in ovariectomized rats.
The Journal of nutritional biochemistry.
2006 Apr; 17(4):282-9. doi:
10.1016/j.jnutbio.2005.05.012. [PMID: 16102959] - Agnieszka Rusińska, Danuta Chlebna-Sokół. Insulin-like growth factor-I and mineral metabolism markers in children with idiopathic decrease in bone mass.
Clinica chimica acta; international journal of clinical chemistry.
2006 Apr; 366(1-2):257-63. doi:
10.1016/j.cca.2005.10.014. [PMID: 16330010] - Chwan-Li Shen, James K Yeh, Jahan Rasty, Yong Li, Bruce A Watkins. Protective effect of dietary long-chain n-3 polyunsaturated fatty acids on bone loss in gonad-intact middle-aged male rats.
The British journal of nutrition.
2006 Mar; 95(3):462-8. doi:
10.1079/bjn20051664. [PMID: 16512931]