[1-[(2,6-Dihydroxy-3,4,5-triphosphonooxycyclohexyl)oxy-hydroxyphosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] octadecanoate (BioDeep_00000914100)
代谢物信息卡片
[1-[(2,6-Dihydroxy-3,4,5-triphosphonooxycyclohexyl)oxy-hydroxyphosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] octadecanoate
化学式: C43H86O22P4 (1078.4560976)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)(O)OC1C(C(C(C(C1O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)O
InChI: InChI=1S/C43H86O22P4/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)61-35(33-59-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)34-60-69(57,58)65-40-38(46)41(62-66(48,49)50)43(64-68(54,55)56)42(39(40)47)63-67(51,52)53/h35,38-43,46-47H,3-34H2,1-2H3,(H,57,58)(H2,48,49,50)(H2,51,52,53)(H2,54,55,56)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sema Erisis, Marcel Hörning. Self-organization of PIP3 waves is controlled by the topology and curvature of cell membranes.
Biophysical journal.
2024 May; 123(9):1058-1068. doi:
10.1016/j.bpj.2024.03.022. [PMID: 38515298] - Mevlut Citir, Rainer Müller, Sebastian Hauke, Alexis Traynor-Kaplan, Carsten Schultz. Monitoring the cellular metabolism of a membrane-permeant photo-caged phosphatidylinositol 3,4,5-trisphosphate derivative.
Chemistry and physics of lipids.
2021 11; 241(?):105124. doi:
10.1016/j.chemphyslip.2021.105124. [PMID: 34509466] - Manuel Olazábal-Morán, Miriam Sánchez-Ortega, Laura Martínez-Muñoz, Carmen Hernández, Manuel S Rodríguez, Mario Mellado, Ana C Carrera. Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL.
Cells.
2021 10; 10(11):. doi:
10.3390/cells10112803. [PMID: 34831026] - Linda Truebestein, Harald Hornegger, Dorothea Anrather, Markus Hartl, Kaelin D Fleming, Jordan T B Stariha, Els Pardon, Jan Steyaert, John E Burke, Thomas A Leonard. Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Proceedings of the National Academy of Sciences of the United States of America.
2021 08; 118(33):. doi:
10.1073/pnas.2101496118. [PMID: 34385319] - Pinaki Chaudhuri, Andrew H Smith, Priya Putta, Linda M Graham, Michael A Rosenbaum. P110α and P110δ catalytic subunits of PI3 kinase regulate lysophosphatidylcholine-induced TRPC6 externalization.
American journal of physiology. Cell physiology.
2021 05; 320(5):C731-C741. doi:
10.1152/ajpcell.00425.2020. [PMID: 33625929] - Reeba Susan Jacob, Cédric Eichmann, Alessandro Dema, Davide Mercadante, Philipp Selenko. α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.
eLife.
2021 02; 10(?):. doi:
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Molecular & cellular proteomics : MCP.
2021; 20(?):100102. doi:
10.1016/j.mcpro.2021.100102. [PMID: 34048982] - Jaewoong Lee, Mark E Robinson, Ning Ma, Dewan Artadji, Mohamed A Ahmed, Gang Xiao, Teresa Sadras, Gauri Deb, Janet Winchester, Kadriye Nehir Cosgun, Huimin Geng, Lai N Chan, Kohei Kume, Teemu P Miettinen, Ye Zhang, Matthew A Nix, Lars Klemm, Chun Wei Chen, Jianjun Chen, Vishal Khairnar, Arun P Wiita, Andrei Thomas-Tikhonenko, Michael Farzan, Jae U Jung, David M Weinstock, Scott R Manalis, Michael S Diamond, Nagarajan Vaidehi, Markus Müschen. IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells.
Nature.
2020 12; 588(7838):491-497. doi:
10.1038/s41586-020-2884-6. [PMID: 33149299] - Agnès Ribes, Antoine Oprescu, Julien Viaud, Karim Hnia, Gaëtan Chicanne, Jean-Marie Xuereb, Sonia Severin, Marie-Pierre Gratacap, Bernard Payrastre. Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics.
The Biochemical journal.
2020 11; 477(22):4327-4342. doi:
10.1042/bcj20190402. [PMID: 33242335] - Narendra Thapa, Mo Chen, Hudson T Horn, Suyong Choi, Tianmu Wen, Richard A Anderson. Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4.
Nature cell biology.
2020 11; 22(11):1357-1370. doi:
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The Biochemical journal.
2020 10; 477(19):3791-3801. doi:
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ACS chemical biology.
2020 07; 15(7):1913-1920. doi:
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Science advances.
2020 07; 6(30):eaba5672. doi:
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2020 04; 10(1):6617. doi:
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2020 03; 97(3):226-236. doi:
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Cell reports.
2019 11; 29(7):2028-2040.e8. doi:
10.1016/j.celrep.2019.10.039. [PMID: 31722215] - Rachel M Furlong, Andrew Lindsay, Karen E Anderson, Phillip T Hawkins, Aideen M Sullivan, Cora O'Neill. The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3.
Journal of cell science.
2019 10; 132(20):. doi:
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Cell reports.
2019 05; 27(7):1979-1990.e7. doi:
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Molecular biology of the cell.
2019 03; 30(5):622-635. doi:
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2019 02; 27(2):371-380.e3. doi:
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FEBS letters.
2019 02; 593(4):395-405. doi:
10.1002/1873-3468.13326. [PMID: 30636036] - Yoshibumi Ueda, Tatsuhito Ii, Yuki Aono, Naotoshi Sugimoto, Seiichi Shinji, Hiroshi Yoshida, Moritoshi Sato. Membrane Dynamics Induced by a Phosphatidylinositol 3,4,5-Trisphosphate Optogenetic Tool.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2019 Jan; 35(1):57-63. doi:
10.2116/analsci.18sdp06. [PMID: 30393242] - Colin D H Ratcliffe, Nadeem Siddiqui, Paula P Coelho, Nancy Laterreur, Tumini N Cookey, Nahum Sonenberg, Morag Park. HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1.
The Journal of cell biology.
2019 01; 218(1):285-298. doi:
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Cell death and differentiation.
2019 01; 26(2):321-331. doi:
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Nutrients.
2018 Sep; 10(10):. doi:
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Molecular cell.
2018 09; 71(6):1092-1104.e5. doi:
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Journal of microbiology and biotechnology.
2018 Aug; 28(8):1401-1411. doi:
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Development (Cambridge, England).
2018 05; 145(11):. doi:
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American journal of physiology. Cell physiology.
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Proceedings of the National Academy of Sciences of the United States of America.
2018 04; 115(17):E3940-E3949. doi:
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Analytical biochemistry.
2018 04; 547(?):66-76. doi:
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Molecules (Basel, Switzerland).
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Biophysical journal.
2018 01; 114(1):126-136. doi:
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PloS one.
2018; 13(2):e0192667. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2017 12; 114(52):13720-13725. doi:
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Biophysical journal.
2017 Dec; 113(11):2396-2405. doi:
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The Journal of cell biology.
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The Journal of biological chemistry.
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Cellular signalling.
2017 07; 35(?):37-47. doi:
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Biochemistry.
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Molecular and cellular biology.
2017 04; 37(7):. doi:
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Nature cell biology.
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Endocrinology.
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Bioorganic & medicinal chemistry letters.
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Journal of human genetics.
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Oncotarget.
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Journal of cell science.
2017 01; 130(2):444-452. doi:
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The Journal of biological chemistry.
2017 Jan; 292(1):251-263. doi:
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The Journal of cell biology.
2017 Jan; 216(1):247-263. doi:
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Methods in enzymology.
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Science signaling.
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Nature cell biology.
2016 Dec; 18(12):1324-1335. doi:
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