7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (BioDeep_00000913961)
代谢物信息卡片
化学式: C14H15N5O5S2 (397.0515)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
InChI: InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7+
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Caizheng Li, Jiayu Sun, Jia Miao, Yongping Qin, Ying Wang, Rujia Yu, Yonghong Xiao. Using Monte Carlo simulation to determine optimal dosing regimen for cefetamet sodium for injection.
Journal of chemotherapy (Florence, Italy).
2016 Jun; 28(3):172-9. doi:
10.1179/1973947814y.0000000214. [PMID: 25252727] - Cai-Zheng Li, Jia-Yu Sun, Ying Wang, Yong-Ping Qin, Jia Miao. [Phase I clinical trial on the safety of injectable cefetamet sodium with a single dose in healthy volunteers].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2014 Jul; 45(4):637-41. doi:
NULL. [PMID: 25286691] - Keumhan Noh, Eunyoung Kim, Wonku Kang. Quantitative determination of cefetamet in human plasma by liquid chromatography-mass spectrometry.
Biomedical chromatography : BMC.
2011 Jul; 25(7):779-82. doi:
10.1002/bmc.1516. [PMID: 20845371] - Mara Aleksić, Ljiljana Milovanović, Vera Kapetanović. Adsorptive stripping voltammetric determination of cefetamet in human urine.
Journal of pharmaceutical and biomedical analysis.
2003 Aug; 32(4-5):957-66. doi:
10.1016/s0731-7085(03)00197-3. [PMID: 12899982] - W Zimmerli, S Sansano, B Wittke. Pharmacokinetics of cefetamet in plasma and skin blister fluid.
Antimicrobial agents and chemotherapy.
1996 Jan; 40(1):102-4. doi:
10.1128/aac.40.1.102. [PMID: 8787888] - T J Fitzgerald. Effects of cefetamet (Ro 15-8074) on Treponema pallidum and experimental syphilis.
Antimicrobial agents and chemotherapy.
1992 Mar; 36(3):598-602. doi:
10.1128/aac.36.3.598. [PMID: 1622168] - W L Hayton, R A Walstad, E Thurmann-Nielsen, T Kufaas, J Kneer, R J Ambros, H E Rugstad, E Monn, E Bodd, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in children.
Antimicrobial agents and chemotherapy.
1991 Apr; 35(4):720-5. doi:
10.1128/aac.35.4.720. [PMID: 2069377] - W L Hayton, J Kneer, R A Blouin, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with hepatic cirrhosis.
Antimicrobial agents and chemotherapy.
1990 Jul; 34(7):1318-22. doi:
10.1128/aac.34.7.1318. [PMID: 2386364] - J Kneer, Y K Tam, R A Blouin, F J Frey, E Keller, C Stathakis, B Luginbuehl, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with renal insufficiency.
Antimicrobial agents and chemotherapy.
1989 Nov; 33(11):1952-7. doi:
10.1128/aac.33.11.1952. [PMID: 2610506] - R A Blouin, J Kneer, K Stoeckel. Pharmacokinetics of intravenous cefetamet (Ro 15-8074) and oral cefetamet pivoxil (Ro 15-8075) in young and elderly subjects.
Antimicrobial agents and chemotherapy.
1989 Mar; 33(3):291-6. doi:
10.1128/aac.33.3.291. [PMID: 2729925] - K Stoeckel, Y K Tam, J Kneer. Pharmacokinetics of oral cefetamet pivoxil (Ro 15-8075) and intravenous cefetamet (Ro 15-8074) in humans: a review.
Current medical research and opinion.
1989; 11(7):432-41. doi:
10.1185/03007998909115930. [PMID: 2673663] - R Wyss, F Bucheli. Determination of cefetamet and its orally active ester, cefetamet pivoxyl, in biological fluids by high-performance liquid chromatography.
Journal of chromatography.
1988 Aug; 430(1):81-92. doi:
10.1016/s0378-4347(00)83136-9. [PMID: 3215964] - J R Koup, U C Dubach, R Brandt, R Wyss, K Stoeckel. Pharmacokinetics of cefetamet (Ro 15-8074) and cefetamet pivoxil (Ro 15-8075) after intravenous and oral doses in humans.
Antimicrobial agents and chemotherapy.
1988 Apr; 32(4):573-9. doi:
10.1128/aac.32.4.573. [PMID: 3377466] - N M Le Saux, L A Slaney, F A Plummer, A R Ronald, R C Brunham. In vitro activity of ceftriaxone, cefetamet (Ro 15-8074), ceftetrame (Ro 19-5247; T-2588), and fleroxacin (Ro 23-6240; AM-833) versus Neisseria gonorrhoeae and Haemophilus ducreyi.
Antimicrobial agents and chemotherapy.
1987 Jul; 31(7):1153-4. doi:
10.1128/aac.31.7.1153. [PMID: 2959199]
