1-[5-[3-Amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]pyrrolidine-2,5-dione (BioDeep_00000913213)

   


代谢物信息卡片


1-[5-[3-Amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]pyrrolidine-2,5-dione

化学式: C22H37N3O15 (583.2224572)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)N(C1=O)C2C(C(C(OC2OC3C(OC(C(C3O)N)O)CO)CO)OC4C(C(C(C(O4)CO)O)O)N)O
InChI: InChI=1S/C22H37N3O15/c23-11-16(33)18(7(4-27)36-20(11)35)40-22-13(25-9(29)1-2-10(25)30)17(34)19(8(5-28)38-22)39-21-12(24)15(32)14(31)6(3-26)37-21/h6-8,11-22,26-28,31-35H,1-5,23-24H2

描述信息

同义名列表

1 个代谢物同义名

1-[5-[3-Amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]pyrrolidine-2,5-dione



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaodi Niu, Li Lin, Lu Liu, Hongsu Wang. Preparation of a novel glucose oxidase-N-succinyl chitosan nanospheres and its antifungal mechanism of action against Colletotrichum gloeosporioides. International journal of biological macromolecules. 2023 Feb; 228(?):681-691. doi: 10.1016/j.ijbiomac.2022.12.171. [PMID: 36549621]
  • Ying Wang, Tanushree Karmakar, Nilanjan Ghosh, Souvik Basak, Nanda Gopal Sahoo. Targeting mangiferin loaded N-succinyl chitosan-alginate grafted nanoparticles against atherosclerosis - A case study against diabetes mediated hyperlipidemia in rat. Food chemistry. 2022 Feb; 370(?):131376. doi: 10.1016/j.foodchem.2021.131376. [PMID: 34662793]
  • Siwen Li, Song Feng, Li Ding, Yuxi Liu, Qiuyun Zhu, Zhiyu Qian, Yueqing Gu. Nanomedicine engulfed by macrophages for targeted tumor therapy. International journal of nanomedicine. 2016 ; 11(?):4107-24. doi: 10.2147/ijn.s110146. [PMID: 27601898]
  • Qiao-ling Zhu, Yi Zhou, Min Guan, Xiao-feng Zhou, Shu-di Yang, Yang Liu, Wei-liang Chen, Chun-ge Zhang, Zhi-qiang Yuan, Chun Liu, Ai-jun Zhu, Xue-nong Zhang. Low-density lipoprotein-coupled N-succinyl chitosan nanoparticles co-delivering siRNA and doxorubicin for hepatocyte-targeted therapy. Biomaterials. 2014 Jul; 35(22):5965-76. doi: 10.1016/j.biomaterials.2014.03.088. [PMID: 24768047]
  • Chun-ge Zhang, Qiao-ling Zhu, Yi Zhou, Yang Liu, Wei-liang Chen, Zhi-Qiang Yuan, Shu-di Yang, Xiao-feng Zhou, Ai-jun Zhu, Xue-nong Zhang, Yong Jin. N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors. International journal of nanomedicine. 2014; 9(?):2919-32. doi: 10.2147/ijn.s59799. [PMID: 24966673]
  • Huiying Luo, He Su, Xiaopeng Wang, Lijuan Wang, Juan Li. N-Succinyl-chitosan nanoparticles induced mitochondria-dependent apoptosis in K562. Molecular and cellular probes. 2012 Aug; 26(4):164-9. doi: 10.1016/j.mcp.2012.03.006. [PMID: 22465598]
  • Huiying Luo, Juan Li, Xuan Chen. Potential role of N-Succinyl-Chitosan in immune reconstitution after umbilical cord blood transplantation in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2011 Dec; 65(8):578-84. doi: 10.1016/j.biopha.2010.01.011. [PMID: 20378302]
  • Xu-Jiang Zhu, Wei Yuan, Ping Li, Xia Liu, Jun-Quan He. Pharmacokinetics of a novel nifedipine and pH-sensitive N-succinyl chitosan/alginate hydrogel bead in rabbits. Drug development and industrial pharmacy. 2010 Dec; 36(12):1463-8. doi: 10.3109/03639045.2010.488644. [PMID: 20704460]
  • Huiying Luo, Juan Li, Xuan Chen. Antitumor effect of N-succinyl-chitosan nanoparticles on K562 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2010 Oct; 64(8):521-6. doi: 10.1016/j.biopha.2009.09.002. [PMID: 19926245]
  • Bo Lu, Yun-Xia Sun, Yun-Qiu Li, Xian-Zheng Zhang, Ren-Xi Zhuo. N-Succinyl-chitosan grafted with low molecular weight polyethylenimine as a serum-resistant gene vector. Molecular bioSystems. 2009 Jun; 5(6):629-37. doi: 10.1039/b822505b. [PMID: 19462020]
  • Yoshinori Kato, Hiraku Onishi, Yoshiharu Machida. N-succinyl-chitosan as a drug carrier: water-insoluble and water-soluble conjugates. Biomaterials. 2004 Feb; 25(5):907-15. doi: 10.1016/s0142-9612(03)00598-2. [PMID: 14609679]
  • Y Kato, H Onishi, Y Machida. Biological characteristics of lactosaminated N-succinyl-chitosan as a liver-specific drug carrier in mice. Journal of controlled release : official journal of the Controlled Release Society. 2001 Feb; 70(3):295-307. doi: 10.1016/s0168-3659(00)00356-4. [PMID: 11182200]
  • Y Kato, H Onishi, Y Machida. Biological fate of highly-succinylated N-succinyl-chitosan and antitumor characteristics of its water-soluble conjugate with mitomycin C at i.v. and i.p. administration into tumor-bearing mice. Biological & pharmaceutical bulletin. 2000 Dec; 23(12):1497-503. doi: 10.1248/bpb.23.1497. [PMID: 11145185]
  • Y Kato, H Onishi, Y Machida. Evaluation of N-succinyl-chitosan as a systemic long-circulating polymer. Biomaterials. 2000 Aug; 21(15):1579-85. doi: 10.1016/s0142-9612(00)00044-2. [PMID: 10885730]
  • K Kamiyama, H Onishi, Y Machida. Biodisposition characteristics of N-succinyl-chitosan and glycol-chitosan in normal and tumor-bearing mice. Biological & pharmaceutical bulletin. 1999 Feb; 22(2):179-86. doi: 10.1248/bpb.22.179. [PMID: 10077438]